標(biāo)題: Titlebook: Chemotherapy of Viral Infections; Paul E. Came,Lawrence A. Caliguiri Book 1982 Springer-Verlag Berlin Heidelberg 1982 Arzneitherapie.Infec [打印本頁] 作者: 迅速 時(shí)間: 2025-3-21 17:51
書目名稱Chemotherapy of Viral Infections影響因子(影響力)
書目名稱Chemotherapy of Viral Infections影響因子(影響力)學(xué)科排名
書目名稱Chemotherapy of Viral Infections網(wǎng)絡(luò)公開度
書目名稱Chemotherapy of Viral Infections網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Chemotherapy of Viral Infections被引頻次
書目名稱Chemotherapy of Viral Infections被引頻次學(xué)科排名
書目名稱Chemotherapy of Viral Infections年度引用
書目名稱Chemotherapy of Viral Infections年度引用學(xué)科排名
書目名稱Chemotherapy of Viral Infections讀者反饋
書目名稱Chemotherapy of Viral Infections讀者反饋學(xué)科排名
作者: hypotension 時(shí)間: 2025-3-21 22:54
Purinescephalitis. While ara-A is not without certain toxic side effects, these are negligible when compared with those of previous antiviral nucleosides, particularly when the compound is given systemically. The approval of this drug for clinical use marked a great stride forward in antiviral chemotherapy作者: maculated 時(shí)間: 2025-3-22 01:34
Interferon and Its Inducersnovel insights into the regulation of gene expression in eukaryotic cells as well as into the pathophysiology of viral diseases. Thus, interferon research represents an important and rapidly advancing area of biomedical research today.作者: 有斑點(diǎn) 時(shí)間: 2025-3-22 05:08 作者: 公式 時(shí)間: 2025-3-22 09:57
Guanidineuanidine. Replication of Sindbis and Semliki Forest viruses of the . genus of the togavirus family (. 1970) and two plant viruses, tobacco necrosis (. 1968) and tobacco mosaic virus (TMV; . 1975) are sensitive to the inhibitor.作者: 節(jié)省 時(shí)間: 2025-3-22 12:59
Phosphonoacetic Acid in normal cells, and these functions serve to give the virus a selective advantage for replication. These virus-specific molecules can provide a target for selective attack on a virus-infected cell since they are absent in normal cells. The herpesviruses induce a new DNA polymerase in infected cell作者: 節(jié)省 時(shí)間: 2025-3-22 18:29
Natural Productslorey came the antibiotic age with all its glowing promise. The search for other natural substances was not as intense as that for synthetic antibacterial agents or antibiotics. Nevertheless, there were individuals who attempted to uncover antiviral agents in the plant, animal, or marine world. It i作者: 機(jī)制 時(shí)間: 2025-3-22 22:10 作者: 拋射物 時(shí)間: 2025-3-23 03:19
https://doi.org/10.1007/978-3-642-37688-7cephalitis. While ara-A is not without certain toxic side effects, these are negligible when compared with those of previous antiviral nucleosides, particularly when the compound is given systemically. The approval of this drug for clinical use marked a great stride forward in antiviral chemotherapy作者: 和平主義者 時(shí)間: 2025-3-23 08:53
Black Holes in General Relativity,novel insights into the regulation of gene expression in eukaryotic cells as well as into the pathophysiology of viral diseases. Thus, interferon research represents an important and rapidly advancing area of biomedical research today.作者: 人類的發(fā)源 時(shí)間: 2025-3-23 10:11 作者: 急急忙忙 時(shí)間: 2025-3-23 17:42 作者: 解開 時(shí)間: 2025-3-23 20:21 作者: Intercept 時(shí)間: 2025-3-23 23:39 作者: Cupidity 時(shí)間: 2025-3-24 04:17
Pathogenesis of Viral Infectionsin cell culture) with some information on the course and outcome of infection (insofar as it can be studied) in the whole animal. A comprehensive review of molecular virologic studies would be so diverse that it would be beyond the scope of this chapter and would probably be superfluous for the majo作者: 無畏 時(shí)間: 2025-3-24 08:35
Pyrimidine Nucleosides with Selective Antiviral Activity” agents, of which several are pyrimidine nucleosides, can effectively inhibit the replication of herpes simplex viruses with little or no host cell toxicity (Fig. 1). Although the exact mechanisms of action of those compounds may not be fully elucidated, it is clear that their selectivity is depend作者: arcane 時(shí)間: 2025-3-24 13:23
Purinesffective as antiviral agents, and are the only class of antiviral drugs which have ultimately reached the hands of practicing physicians for widespread clinical use against herpesvirus. Although the pyrimidine nucleoside, 5-iodo-2′-deoxyuridine (idoxuridine, IdUrd), was the first of these to do so, 作者: 珊瑚 時(shí)間: 2025-3-24 16:33 作者: 共棲 時(shí)間: 2025-3-24 21:22 作者: 姑姑在炫耀 時(shí)間: 2025-3-25 02:55 作者: 放肆的我 時(shí)間: 2025-3-25 04:05
Immunotherapy and Immunoregulationeen recognized for centuries. In eighteenth century Europe, variolation was practiced as a crude form of immunization to protect against smallpox. This eventually led to Jenner’s acclaimed experiments in which he successfully used vaccine for the first time, employing a “l(fā)ive, attentuated virus” for作者: MARS 時(shí)間: 2025-3-25 09:35
Guanidinenitial discovery, mutants that were either resistant to or dependent upon guanidine were described (. et al. 1963; . et al. 1963). In general, growth of many members of the Picornaviridae family, which comprises a large number of lipid-free animal viruses that contain single-stranded RNA genomes, is作者: 大看臺(tái) 時(shí)間: 2025-3-25 13:59 作者: BIBLE 時(shí)間: 2025-3-25 15:54
Arildone: A ,-Diketoneiral activity with promising results. One of these compounds, arildone, was extensively studied and shown to be active against a wide variety of DNA and RNA viruses in vitro. In addition, arildone was shown to be effective against herpesvirus infections in vivo. Arildone and its metabolites were wel作者: 圍巾 時(shí)間: 2025-3-25 22:52 作者: Nerve-Block 時(shí)間: 2025-3-26 03:34 作者: barium-study 時(shí)間: 2025-3-26 06:00
Rifamycinsa an aliphatic ansa chain. Originally, a mixture of five compounds, designated rifamycins A–E, was isolated from the fermentation broth of . (. et al. 1959 a, b). It was subsequently found that one of the compounds, rifamycin B, was produced almost exclusively when sodium diethylbarbiturate was pres作者: 得意人 時(shí)間: 2025-3-26 11:14 作者: LANCE 時(shí)間: 2025-3-26 12:41
0171-2004 the basic disciplines of virology, immunology, and pharmacology continue to advance the understanding of the pathogenesis and control of virus diseases. At the same time, the rational development of antiviral agents is attracting, to an increasing extent, the interest of workers in other discipline作者: Inoperable 時(shí)間: 2025-3-26 17:41 作者: hysterectomy 時(shí)間: 2025-3-26 22:05 作者: 原告 時(shí)間: 2025-3-27 04:01
https://doi.org/10.1007/978-3-642-36478-5ost’s immune response to virus infection can play several roles: it can provide both short- and long-term assistance in combating the infection, but also may be at least partially responsible for development of disease symptoms.作者: 褪色 時(shí)間: 2025-3-27 08:36 作者: 前奏曲 時(shí)間: 2025-3-27 09:57 作者: Libido 時(shí)間: 2025-3-27 15:49 作者: Watemelon 時(shí)間: 2025-3-27 21:30 作者: adj憂郁的 時(shí)間: 2025-3-28 00:30
Yi Deng,Akshay Rajhans,A. Agung Juliusf cutaneous herpetic infections in humans. Currently, arildone is undergoing clinical trials for herpesvirus infections in the United States, Asia, and Europe. This review summarizes the current state of knowledge concerning the antiviral activity and possible mode of action of arildone.作者: 暫停,間歇 時(shí)間: 2025-3-28 03:31 作者: Neutral-Spine 時(shí)間: 2025-3-28 07:22
Arildone: A ,-Diketonef cutaneous herpetic infections in humans. Currently, arildone is undergoing clinical trials for herpesvirus infections in the United States, Asia, and Europe. This review summarizes the current state of knowledge concerning the antiviral activity and possible mode of action of arildone.作者: 谷物 時(shí)間: 2025-3-28 14:03
The Thiosemicarbazones structure and antiviral activity. Furthermore, these compounds were the first to be effective in humans and placed in clinical medicine Finally, there are no other compounds known which appear able to block the genetic expression of such a wide variety of viruses.作者: 祖?zhèn)髫?cái)產(chǎn) 時(shí)間: 2025-3-28 14:42 作者: propose 時(shí)間: 2025-3-28 21:38 作者: Radiculopathy 時(shí)間: 2025-3-28 23:29
Measurement and the Quantum World,” agents, of which several are pyrimidine nucleosides, can effectively inhibit the replication of herpes simplex viruses with little or no host cell toxicity (Fig. 1). Although the exact mechanisms of action of those compounds may not be fully elucidated, it is clear that their selectivity is depend作者: vocation 時(shí)間: 2025-3-29 03:34
https://doi.org/10.1007/978-3-642-37688-7ffective as antiviral agents, and are the only class of antiviral drugs which have ultimately reached the hands of practicing physicians for widespread clinical use against herpesvirus. Although the pyrimidine nucleoside, 5-iodo-2′-deoxyuridine (idoxuridine, IdUrd), was the first of these to do so, 作者: 著名 時(shí)間: 2025-3-29 09:58 作者: mettlesome 時(shí)間: 2025-3-29 15:13
Rahul Johari,Neelima Gupta,Sandhya Anejaces to be synthesized; although a number of random events had to take place before their potential was realized. The thiosemicarbazones were the first compounds to be found active in virus-infected animals. They were also the focus of the first systematic studies on the relationship between chemical作者: 縱欲 時(shí)間: 2025-3-29 18:12
Black Holes in General Relativity,by a wide variety of RNA-containing or DNA-containing viruses. In addition to a marked antiviral effect, interferons cause numerous changes in the phenotype of target cells, including a reduction in the rate of cell proliferation and alterations in the structure and function of the cell surface, the作者: Connotation 時(shí)間: 2025-3-29 20:55
https://doi.org/10.1007/978-3-642-38939-9een recognized for centuries. In eighteenth century Europe, variolation was practiced as a crude form of immunization to protect against smallpox. This eventually led to Jenner’s acclaimed experiments in which he successfully used vaccine for the first time, employing a “l(fā)ive, attentuated virus” for作者: decode 時(shí)間: 2025-3-30 02:42 作者: Exclude 時(shí)間: 2025-3-30 04:38
https://doi.org/10.1007/978-3-642-39937-4 placed on the effects of these compounds in the virus-infected and uninfected organism. Several reviews on the subject have appeared in the last two decades (. and . 1963 a; . and . 1966; . and . 1972; . and . 1973). I shall not deal in any detail with the effects of halogenated ribofuranosyl-benzi作者: 我不明白 時(shí)間: 2025-3-30 10:59
Yi Deng,Akshay Rajhans,A. Agung Juliusiral activity with promising results. One of these compounds, arildone, was extensively studied and shown to be active against a wide variety of DNA and RNA viruses in vitro. In addition, arildone was shown to be effective against herpesvirus infections in vivo. Arildone and its metabolites were wel作者: 懶惰民族 時(shí)間: 2025-3-30 12:57 作者: Prognosis 時(shí)間: 2025-3-30 19:55
https://doi.org/10.1007/978-3-642-40916-5s such as rauwolfia alkaloids, opium, belladonna, and digitalis continue to be used in modern medicine. With the exception of antibiotics, the use of natural substances in the area of infectious disease has not met with the success apparent in other areas of human disease. Until Pasteur, Koch, Semme作者: Carcinogen 時(shí)間: 2025-3-30 22:25
https://doi.org/10.1007/978-3-642-41002-4a an aliphatic ansa chain. Originally, a mixture of five compounds, designated rifamycins A–E, was isolated from the fermentation broth of . (. et al. 1959 a, b). It was subsequently found that one of the compounds, rifamycin B, was produced almost exclusively when sodium diethylbarbiturate was pres作者: 積習(xí)難改 時(shí)間: 2025-3-31 02:01
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/c/image/224976.jpg作者: Landlocked 時(shí)間: 2025-3-31 06:15 作者: Verify 時(shí)間: 2025-3-31 12:57
https://doi.org/10.1007/978-3-642-37688-7United States. However, despite the demonstrated efficacy of this compound in the prophylaxis (and more recently in the treatment) of influenza A virus infections, it has never been widely employed and its recommended use remains the subject of considerable controversy (. 1978).
