標(biāo)題: Titlebook: Chemical Mixtures and Combined Chemical and Nonchemical Stressors; Exposure, Toxicity, Cynthia V. Rider,Jane Ellen Simmons Book 2018 Sprin [打印本頁] 作者: Nonchalant 時間: 2025-3-21 17:19
書目名稱Chemical Mixtures and Combined Chemical and Nonchemical Stressors影響因子(影響力)
書目名稱Chemical Mixtures and Combined Chemical and Nonchemical Stressors影響因子(影響力)學(xué)科排名
書目名稱Chemical Mixtures and Combined Chemical and Nonchemical Stressors網(wǎng)絡(luò)公開度
書目名稱Chemical Mixtures and Combined Chemical and Nonchemical Stressors網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Chemical Mixtures and Combined Chemical and Nonchemical Stressors被引頻次
書目名稱Chemical Mixtures and Combined Chemical and Nonchemical Stressors被引頻次學(xué)科排名
書目名稱Chemical Mixtures and Combined Chemical and Nonchemical Stressors年度引用
書目名稱Chemical Mixtures and Combined Chemical and Nonchemical Stressors年度引用學(xué)科排名
書目名稱Chemical Mixtures and Combined Chemical and Nonchemical Stressors讀者反饋
書目名稱Chemical Mixtures and Combined Chemical and Nonchemical Stressors讀者反饋學(xué)科排名
作者: DOSE 時間: 2025-3-21 21:32 作者: Outspoken 時間: 2025-3-22 01:12
Considerations for Measuring Exposure to Chemical Mixturesdied with regard to environmental occurrence and to toxicity. If a commercial chemical standard does not exist for a given chemical, then little to no quantitative data likely exists for that chemical. This chapter discusses exposures to organic chemical mixtures, lists necessary considerations for 作者: extemporaneous 時間: 2025-3-22 05:18 作者: 把手 時間: 2025-3-22 12:34 作者: neutralize 時間: 2025-3-22 15:59 作者: neutralize 時間: 2025-3-22 18:06
Adverse Outcome Pathways to Support the Assessment of Chemical Mixtures the use of less costly alternative techniques. The adverse outcome pathway (AOP) concept has emerged as a scaffold for organizing mechanistic information from these methods. Two main elements – key events (KEs) and key event relationships (KERs) – are utilized to describe the underlying mechanism o作者: 厚顏 時間: 2025-3-22 21:58 作者: LIEN 時間: 2025-3-23 02:51 作者: sclera 時間: 2025-3-23 09:14
Mixtures: Contrasting Perspectives from Toxicology and Epidemiologyinto the commonalities and differences in the viewpoint and methods that toxicologists and epidemiologists use to investigate health effects of mixtures. Ways in which these two important disciplines can work together are suggested.作者: sorbitol 時間: 2025-3-23 11:57 作者: DRAFT 時間: 2025-3-23 14:20
Physiologically Based Pharmacokinetic Modeling of Chemical Mixturesdosimetry simulations in risk assessment and in pharmaceutical sciences. Because this tool can use chemical and physiological information/data from different sources (i.e., in vitro, in vivo, in silico), it is also being increasingly used for mixture exposures, especially for mixtures containing che作者: Champion 時間: 2025-3-23 19:52
Mixture Experimental Designhere has been considerable progress over the past decades, further improvement is necessary both in the development and application of experimental designs to yield data suitable for quantitative analytic methods and in the implementation of appropriate statistical analyses. This chapter reviews the作者: eucalyptus 時間: 2025-3-24 01:12 作者: 許可 時間: 2025-3-24 05:53 作者: ADJ 時間: 2025-3-24 08:39 作者: 嬉耍 時間: 2025-3-24 13:03
Book 2018k associated with combined exposures.?This book will provide an introduction to key issues and multiple options for evaluating both the toxicity of mixtures as well as the risk associated with exposure to mixtures.?Additionally, promising tools adapted from other disciplines will be discussed in the作者: Peculate 時間: 2025-3-24 17:19 作者: creditor 時間: 2025-3-24 19:04 作者: 障礙 時間: 2025-3-25 00:15 作者: STIT 時間: 2025-3-25 05:08
Lecture Notes in Electrical Engineering concentrations of the chemicals or their metabolites or adducts in human specimens). In this chapter, we will discuss the suitability of biomonitoring data for evaluating exposures to mixtures of environmental chemicals.作者: 詞匯記憶方法 時間: 2025-3-25 07:44
Federico Marangoni,Gernot Krammerwn approach. Considering the numerous perspectives and approaches, mixture terminology has been particularly challenging. In this introductory chapter, we lay the groundwork for the book by providing a rationale for the study of mixtures, defining important terms, and describing the flow of the book.作者: Permanent 時間: 2025-3-25 15:11 作者: COUCH 時間: 2025-3-25 17:32
Kent L. Granzin,Kenneth D. Bahnents. As such, tests for departure from additivity in mixtures should accommodate both nonlinear relationships and efficient experimental designs. In this chapter, we illustrate the strategy using three different basic assumptions about the underlying response surface from single chemical data.作者: Commodious 時間: 2025-3-25 22:45 作者: insurgent 時間: 2025-3-26 02:42 作者: 投票 時間: 2025-3-26 05:00 作者: forbid 時間: 2025-3-26 08:55
s for prioritizing mixtures for study.Surveys what is known In this book, both basic and advanced concepts are discussed for considering mixtures from initial exposure characterization through evaluation of risk associated with combined exposures.?This book will provide an introduction to key issues作者: AVOW 時間: 2025-3-26 13:32
https://doi.org/10.1007/BFb0060247tion study” (EWAS) analytic approach to identify a number of environmental exposures in human disease. With the advent of high-throughput environmental exposure information (e.g., exposome), methods such as EWAS will be instrumental to accelerate discovery in disease.作者: 松緊帶 時間: 2025-3-26 19:25 作者: 直覺好 時間: 2025-3-26 23:16 作者: Condyle 時間: 2025-3-27 01:22 作者: 施加 時間: 2025-3-27 09:12
Adverse Outcome Pathways to Support the Assessment of Chemical Mixturesconsidering mechanistic data in a mixtures assessment. The use of this concept provides a means to allow more specificity when deciding whether to use dose addition, independent action or integrated addition risk assessment methodologies. Furthermore, AOPs enable novel approaches for determining che作者: Initial 時間: 2025-3-27 09:26
Dose-Response Modelingoice of functional form used to describe how the mean response changes as dose increases as well as the evaluation of how well the chosen form fits the data at hand. The chapter also points out that proper modeling of the variability inherent in the structure of the data is crucial to efficient stat作者: 建筑師 時間: 2025-3-27 16:45 作者: Exuberance 時間: 2025-3-27 20:18
Mixture Experimental Designtatistical mixture designs such as the isobologram and the fixed ratio ray. General considerations are provided that will aid in the development of both experimental design and analysis strategies that address the question(s) being asked.作者: membrane 時間: 2025-3-27 23:55 作者: 繁榮中國 時間: 2025-3-28 04:57 作者: 允許 時間: 2025-3-28 07:02
Chemical Mixtures and Combined Chemical and Nonchemical StressorsExposure, Toxicity, 作者: 繁榮地區(qū) 時間: 2025-3-28 10:56 作者: nostrum 時間: 2025-3-28 16:17
a significant challenge. This book will be an essential resource for researchers and professionals in the fields of toxicology, epidemiology, exposure science,risk assessment, and statistics.978-3-030-09617-5978-3-319-56234-6作者: Promotion 時間: 2025-3-28 22:25 作者: 逃避責(zé)任 時間: 2025-3-29 02:41
https://doi.org/10.1007/978-3-319-32817-1 biomonitoring data, highlighting the need for integrated modeling tools that allow the functional link among exposure, internal dose and biomonitoring data. Extrapolation of exposure estimates from individual data to population exposure through advanced probabilistic techniques and agent-based mode作者: 貿(mào)易 時間: 2025-3-29 05:13
Wenzhu Zhang,Ran Wang,Ting Yuan,Zhigang Wuconsidering mechanistic data in a mixtures assessment. The use of this concept provides a means to allow more specificity when deciding whether to use dose addition, independent action or integrated addition risk assessment methodologies. Furthermore, AOPs enable novel approaches for determining che作者: evasive 時間: 2025-3-29 10:07 作者: incisive 時間: 2025-3-29 13:17
Product Dispossession: A Conceptual Approached to explore mechanisms of joint action. In general, the steps for investigating joint toxicity using additivity models include (1) deciding on which additivity model(s) to apply (e.g., dose addition, independent action, or both), (2) collecting dose-response data on individual chemicals?and the mi作者: Ardent 時間: 2025-3-29 19:20
https://doi.org/10.1007/978-3-319-13084-2tatistical mixture designs such as the isobologram and the fixed ratio ray. General considerations are provided that will aid in the development of both experimental design and analysis strategies that address the question(s) being asked.作者: mastoid-bone 時間: 2025-3-29 21:18
Lecture Notes in Electrical Engineeringce system for binary mixtures allows the hazard index to be modified to incorporate toxicological interactions. Relative potency factors are applied in a dose addition formula and are developed for chemicals that have good evidence of toxicological similarity, e.g., chemicals that share a common adv作者: indifferent 時間: 2025-3-30 00:54
Yajun Cai,Yilong Zhang,Huanhuan Wu, the risk assessment could be based on surrogate toxicity information obtained from testing a sufficiently similar mixture. Biostatistical approaches for evaluating whether mixtures are sufficiently similar are included here as potential approaches that may, with further evaluation, prove useful in作者: obsolete 時間: 2025-3-30 07:38 作者: Flinch 時間: 2025-3-30 08:45
Cynthia V. Rider,Jane Ellen SimmonsPresents the available mixture models in a clear and simple way, allowing readers to apply tools to their own research.Includes novel methods for prioritizing mixtures for study.Surveys what is known 作者: 軌道 時間: 2025-3-30 13:55
http://image.papertrans.cn/c/image/224364.jpg作者: bleach 時間: 2025-3-30 20:02 作者: FACT 時間: 2025-3-30 23:17
Lecture Notes in Electrical Engineeringbecause human exposure does not occur under controlled conditions of dose-response evaluations in animal studies, exposure assessment is complex. Three main tools have been used to assess human exposures: history/questionnaire information, environmental monitoring, and biomonitoring (i.e., measuring作者: sebaceous-gland 時間: 2025-3-31 00:59
