標題: Titlebook: Challenges and Opportunities for Respiratory Syncytial Virus Vaccines; Larry J. Anderson,Barney S. Graham Book 2013 The Editor(s) (if appl [打印本頁] 作者: 冠軍 時間: 2025-3-21 19:39
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書目名稱Challenges and Opportunities for Respiratory Syncytial Virus Vaccines網絡公開度學科排名
書目名稱Challenges and Opportunities for Respiratory Syncytial Virus Vaccines被引頻次
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書目名稱Challenges and Opportunities for Respiratory Syncytial Virus Vaccines讀者反饋
書目名稱Challenges and Opportunities for Respiratory Syncytial Virus Vaccines讀者反饋學科排名
作者: 波動 時間: 2025-3-22 00:11 作者: 靦腆 時間: 2025-3-22 02:29 作者: 用不完 時間: 2025-3-22 08:27
Structure and Function of Respiratory Syncytial Virus Surface Glycoproteins (F), control the initial phases of infection. G targets the ciliated cells of the airways, and F causes the virion membrane to fuse with the target cell membrane. The F protein is the major target for antiviral drug development, and both G and F glycoproteins are the antigens targeted by neutralizi作者: excrete 時間: 2025-3-22 10:33
Respiratory Syncytial Virus and Reactive Airway Diseaseg, either by causing bronchiolitis or by inducing acute exacerbations of asthma. There has been a long-standing interest in whether severe RSV bronchiolitis in infancy is a risk factor for the development of asthma later in childhood. While epidemiologic studies have suggested that such a link exist作者: 建筑師 時間: 2025-3-22 13:39
Human Genetics and Respiratory Syncytial Virus Disease: Current Findings and Future Approachesvere bronchiolitis and pneumonia. Although there are several known risk factors for severe RSV disease, namely, premature birth, chronic lung disease, congenital heart disease, and T cell immunodeficiency, the majority of young children who develop severe RSV disease are otherwise healthy children. 作者: 建筑師 時間: 2025-3-22 19:19 作者: 網絡添麻煩 時間: 2025-3-22 23:11 作者: 粗糙濫制 時間: 2025-3-23 02:40
Respiratory Syncytial Virus Mechanisms to Interfere with Type 1 Interferonsection by these viruses triggers the innate antiviral response of the host, mainly type I interferon (IFN). Essentially all other viruses of this family produce IFN suppressor functions by co-transcriptional RNA editing. In contrast, RSV has evolved two unique nonstructural proteins, NS1 and NS2, to作者: panorama 時間: 2025-3-23 06:36
Host Gene Expression and Respiratory Syncytial Virus Infectioncell response screening that enable genome-wide analysis of cell factors involved in viral replication and disease. Application of both experimental and computational biology approaches have led to crucial insights into virus infection, its life cycle, and host gene targets for disease intervention.作者: 樹上結蜜糖 時間: 2025-3-23 12:45
Consequences of Immature and Senescent Immune Responses for Infection with Respiratory Syncytial Viriated morbidity and mortality. While other factors play a role in the risk these groups assume, shortcomings of the immune response make a substantial contribution to the predisposition to severe disease. Ineffectual antibody production with misdirected cytokine responses and excess inflammation in 作者: 流浪者 時間: 2025-3-23 17:05
Respiratory Syncytial Virus Disease: Prevention and Treatmenter the past decade, the most significant advance in the prevention of RSV disease has been the development of high-titered antibody products. Infection control is the only other strategy to prevent RSV disease. A humanized monoclonal antibody directed against the fusion (F) protein palivizumab, (Syn作者: 地殼 時間: 2025-3-23 20:21
Live-Attenuated Respiratory Syncytial Virus Vaccinesuse vaccine-associated enhanced RSV disease; (2) they broadly stimulate innate, humoral, and cellular immunity, both systemically and locally in the respiratory tract; (3) they are delivered intranasally; and (4) they replicate in the upper respiratory tract of young infants despite the presence of 作者: Prognosis 時間: 2025-3-24 00:21 作者: 可商量 時間: 2025-3-24 06:23 作者: 冰河期 時間: 2025-3-24 09:36
Challenges and Opportunities for Respiratory Syncytial Virus Vaccines978-3-642-38919-1Series ISSN 0070-217X Series E-ISSN 2196-9965 作者: nerve-sparing 時間: 2025-3-24 14:04 作者: HUMID 時間: 2025-3-24 16:25 作者: 災難 時間: 2025-3-24 19:50
Internationale Gerontologische Gespr?cheily in terms of the number of genes and proteins. It is also relatively divergent and distinct from the prototype members of the family. In the past 30?years, we have seen a tremendous increase in our understanding of the molecular biology of RSV based on a succession of advances involving molecular作者: BOLUS 時間: 2025-3-24 23:37
https://doi.org/10.1007/978-3-642-85417-0tract illness in infants <1?year of age. RSV also causes repeat infections and significant disease throughout life. In addition to the young child, persons with compromised immune, pulmonary or cardiac systems, and the elderly have significant risk from infection. Though RSV causes the full spectrum作者: TRACE 時間: 2025-3-25 05:17
Partnerschaft und Sexualit?t im Alters. Circulating viruses have been classified into two antigenic groups (A and B) that correlate with well-delineated genetic groups. Most sequence and antigenic differences (both inter- and intra-groups) accumulate in two hypervariable segments of the G-protein gene. Sequences of the G gene have been作者: foppish 時間: 2025-3-25 11:07
Partnerschaft und Sexualit?t im Alter (F), control the initial phases of infection. G targets the ciliated cells of the airways, and F causes the virion membrane to fuse with the target cell membrane. The F protein is the major target for antiviral drug development, and both G and F glycoproteins are the antigens targeted by neutralizi作者: 施舍 時間: 2025-3-25 11:40 作者: Ossification 時間: 2025-3-25 16:11 作者: Hallmark 時間: 2025-3-25 21:20 作者: Fallibility 時間: 2025-3-26 00:32
Partnerschaft, Sexualit?t und Fruchtbarkeitf CD4 and CD8 T cells play a critical role in terminating an acute RSV infection whereas antibodies can provide protection from re-infection. Despite eliciting an immune response that mediates clearance of the virus, immunity to the virus appears to wane over time and individuals remain susceptible 作者: 樸素 時間: 2025-3-26 05:58 作者: 貪婪地吃 時間: 2025-3-26 11:41
https://doi.org/10.1007/978-3-540-48845-3cell response screening that enable genome-wide analysis of cell factors involved in viral replication and disease. Application of both experimental and computational biology approaches have led to crucial insights into virus infection, its life cycle, and host gene targets for disease intervention.作者: 罵人有污點 時間: 2025-3-26 12:51 作者: Prosaic 時間: 2025-3-26 17:13
Kommunikation I: Wie sage ich es?,er the past decade, the most significant advance in the prevention of RSV disease has been the development of high-titered antibody products. Infection control is the only other strategy to prevent RSV disease. A humanized monoclonal antibody directed against the fusion (F) protein palivizumab, (Syn作者: Iniquitous 時間: 2025-3-26 22:32
,Das Konfliktgespr?ch: Wie l?sen wir es?,use vaccine-associated enhanced RSV disease; (2) they broadly stimulate innate, humoral, and cellular immunity, both systemically and locally in the respiratory tract; (3) they are delivered intranasally; and (4) they replicate in the upper respiratory tract of young infants despite the presence of 作者: acrobat 時間: 2025-3-27 02:12
Absprachen: Wie setzen wir es um?,op a licensed vaccine is not due to lack of effort, as numerous vaccine candidates have been characterized in preclinical and clinical studies spanning five decades. The vaccine candidates thus far explored can be generally divided into four categories: (1) whole inactivated virus, (2) replication c作者: 哀悼 時間: 2025-3-27 06:52 作者: Delectable 時間: 2025-3-27 12:05
https://doi.org/10.1007/978-3-642-38919-1Epidemiology; Pathogenesis; RSV; Virology; Virus infection; vaccines; infectious diseases作者: Indurate 時間: 2025-3-27 14:35
978-3-662-52155-7The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE作者: offense 時間: 2025-3-27 20:49 作者: 薄荷醇 時間: 2025-3-28 00:55
C. Br?hler,V. Weiss,W. Meyh?fertment of immune cells as well as promote anti-viral responses. In this review, we summarize the results of numerous studies that have characterized the innate immune responses that contribute to the RSV-induced responses and may be important considerations for the development of efficacious vaccine strategies.作者: 摻假 時間: 2025-3-28 05:27
https://doi.org/10.1007/978-3-540-48845-3ene discovery and transcriptome profiling for respiratory syncytial virus (RSV) are discussed in the context of biological relevance for disease intervention in the clinical setting and vaccine development.作者: Obligatory 時間: 2025-3-28 07:18
Respiratory Syncytial Virus and Reactive Airway Diseasegesting that instead of being causal, severe RSV infection may instead be a marker of a predisposing factor for asthma. In this chapter, we will explore the evidence that RSV infection leads to RAD in infants and adults, and how these different forms of RAD may be linked.作者: 歡騰 時間: 2025-3-28 11:22
Innate Immune Responses to Respiratory Syncytial Virus Infectiontment of immune cells as well as promote anti-viral responses. In this review, we summarize the results of numerous studies that have characterized the innate immune responses that contribute to the RSV-induced responses and may be important considerations for the development of efficacious vaccine strategies.作者: Spartan 時間: 2025-3-28 17:13
Host Gene Expression and Respiratory Syncytial Virus Infectionene discovery and transcriptome profiling for respiratory syncytial virus (RSV) are discussed in the context of biological relevance for disease intervention in the clinical setting and vaccine development.作者: 細節(jié) 時間: 2025-3-28 21:40
Book 2013imal and tissue culture models of RSV infection. It is designed to organize the critical information relevant to RSV vaccine development, facilitate the assimilation of data, and speed progress toward producing a safe and effective vaccine. .作者: ALIEN 時間: 2025-3-29 01:48 作者: Infinitesimal 時間: 2025-3-29 03:41
Structure and Function of Respiratory Syncytial Virus Surface Glycoproteinsng antibodies induced by infection. In this chapter, we review the structure and function of the RSV surface glycoproteins, including recent X-ray crystallographic data of the F glycoprotein in its pre- and postfusion conformations, and discuss how this information informs antigen selection and vaccine development.作者: 饑荒 時間: 2025-3-29 10:26 作者: 離開真充足 時間: 2025-3-29 14:41
C. Br?hler,V. Weiss,W. Meyh?ferr functions. While the mechanism of action of NS1 and NS2 is a subject of active research, their effect on adaptive immunity is also being recognized. In this review, we discuss various aspects of NS1 and NS2 function with implications for vaccine design.作者: Asymptomatic 時間: 2025-3-29 16:38 作者: synovium 時間: 2025-3-29 23:18 作者: 調整校對 時間: 2025-3-30 02:10
Respiratory Syncytial Virus Mechanisms to Interfere with Type 1 Interferonsr functions. While the mechanism of action of NS1 and NS2 is a subject of active research, their effect on adaptive immunity is also being recognized. In this review, we discuss various aspects of NS1 and NS2 function with implications for vaccine design.作者: excrete 時間: 2025-3-30 06:13
Consequences of Immature and Senescent Immune Responses for Infection with Respiratory Syncytial Vire better understood. Preventative approaches to decreasing the burden of disease are preferable to therapeutic intervention and effective vaccination strategies will need to target the strengths of the immune responses in these populations.作者: 招募 時間: 2025-3-30 09:18 作者: 預示 時間: 2025-3-30 15:23 作者: 推遲 時間: 2025-3-30 17:21 作者: grandiose 時間: 2025-3-31 00:44 作者: Leaven 時間: 2025-3-31 04:24
Respiratory Syncytial Virus: Virology, Reverse Genetics, and Pathogenesis of Diseasethis complication. However, development of subunit or other protein-based vaccines for pediatric use is hampered by the possibility of enhanced disease and the difficulty of reliably demonstrating its absence in preclinical studies.作者: 否決 時間: 2025-3-31 06:27
Clinical and Epidemiologic Features of Respiratory Syncytial Virusan be a serious nosocomial pathogen in high risk individuals but nosocomial transmission that can often be prevented with meticulous attention to good infection control practices. High risk groups include the premature infants and persons of any age with compromised cardiac, pulmonary, or immune sys
