標(biāo)題: Titlebook: Cerebral Ischemia and Basic Mechanisms; Alexander Hartmann,Frank Yatsu,Wolfgang Kuschinsky Conference proceedings 1994 Springer-Verlag Ber [打印本頁] 作者: culinary 時(shí)間: 2025-3-21 19:43
書目名稱Cerebral Ischemia and Basic Mechanisms影響因子(影響力)
書目名稱Cerebral Ischemia and Basic Mechanisms影響因子(影響力)學(xué)科排名
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書目名稱Cerebral Ischemia and Basic Mechanisms網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Cerebral Ischemia and Basic Mechanisms被引頻次
書目名稱Cerebral Ischemia and Basic Mechanisms被引頻次學(xué)科排名
書目名稱Cerebral Ischemia and Basic Mechanisms年度引用
書目名稱Cerebral Ischemia and Basic Mechanisms年度引用學(xué)科排名
書目名稱Cerebral Ischemia and Basic Mechanisms讀者反饋
書目名稱Cerebral Ischemia and Basic Mechanisms讀者反饋學(xué)科排名
作者: Metamorphosis 時(shí)間: 2025-3-21 21:41
Aspects of Acid-Base Homeostasis in Ischemiant to assess the events occurring in the extracellular fluid as it is the neuronal microenvironment where neurotransmitters and drugs are available to receptors. This chapter concentrates on new data related to changes detected in the extracellular fluid.作者: 間接 時(shí)間: 2025-3-22 03:11 作者: 討好女人 時(shí)間: 2025-3-22 07:42
Otfrid Foerster · Arzt und Naturforscher explanations for these results include differences in vulnerability between human and animal neurons, lower dose tolerance due to coexisting cardiovascular disease, and insensitivity in methods of detecting modest neuronal protection in humans.作者: Limited 時(shí)間: 2025-3-22 09:21 作者: visual-cortex 時(shí)間: 2025-3-22 16:53 作者: visual-cortex 時(shí)間: 2025-3-22 20:19
https://doi.org/10.1007/978-3-662-25227-7nt to assess the events occurring in the extracellular fluid as it is the neuronal microenvironment where neurotransmitters and drugs are available to receptors. This chapter concentrates on new data related to changes detected in the extracellular fluid.作者: 拱形大橋 時(shí)間: 2025-3-23 01:01
https://doi.org/10.1007/978-3-662-25234-5resonance (NMR) spectroscopy which allow an image of the energy metabolism of brain to be obtained noninvasively. First, the paper outlines the techniques used for localization and their reliability. These are then illustrated with example from brain observations.作者: 窗簾等 時(shí)間: 2025-3-23 03:47 作者: 跳動 時(shí)間: 2025-3-23 07:08 作者: 褪色 時(shí)間: 2025-3-23 11:20 作者: Kinetic 時(shí)間: 2025-3-23 17:40
https://doi.org/10.1007/978-3-662-28348-6list but think about how to make use of these negative experiences as examples of methodological errors which should not be repeated. Thus, studies with a poor diagnostic characterization of patients due to the lack of a computed tomography (CT) scan and trials carried out using insufficient sample sizes should never be performed.作者: Melodrama 時(shí)間: 2025-3-23 18:06
Effects of Extracellular Acidosis on Glial Cell Intracellular pH: Evidence for a Glial Spatial H+-Bumic subjects - where lactic acid may accumulate to 20–30 mM and higher concentrations (Rehncrona et al. 1980; Katsura et al. 1991). Tissue pH may drop to pH 5.5 (Chopp et al. 1988). In consequence, acidosis has since long been suspected as a mediator of brain damage (Siesj? 1981).作者: 恭維 時(shí)間: 2025-3-24 02:03 作者: 事物的方面 時(shí)間: 2025-3-24 03:44
What Are We Learning from Clinical Trials in Acute Cerebral Ischemia?list but think about how to make use of these negative experiences as examples of methodological errors which should not be repeated. Thus, studies with a poor diagnostic characterization of patients due to the lack of a computed tomography (CT) scan and trials carried out using insufficient sample sizes should never be performed.作者: Arteriography 時(shí)間: 2025-3-24 06:44
Conference proceedings 1994ational conference on Cerebral Ischemia and Basic Mechanisms held in Bad Schachen/Lake Constance, Germany in June 1992. The enormous progress in research recently on the basic mechanisms associated with cerebral ischemia has provided greater insight into the pathophysiological mechanisms of reduced 作者: avarice 時(shí)間: 2025-3-24 11:11 作者: 拖網(wǎng) 時(shí)間: 2025-3-24 18:34
https://doi.org/10.1007/978-3-662-26794-3tracellular messengers and mitochondrial metabolism [31]. Experimental studies of cerebral ischemia in animal models have shown that pretreatment with the calcium entry antagonist nimodipine results in protection of the brain from cerbral infarction by preventing calcium entry into ischemic neurones and glia [1].作者: MAPLE 時(shí)間: 2025-3-24 22:53
Otfrid Foerster · Arzt und Naturforscher delay providing a potential window of opportunity for therapeutic intervention. Thus, understanding these processes seems to offer hope for the more effective treatment of brain ischemia and stroke [13].作者: Altitude 時(shí)間: 2025-3-24 23:47
Uncoupling of Flow and Metabolism in Early Ischemic Strokel setting, however, is extremely difficult since most routine examinations do not yield evidence for viability of tissue, and regional studies of physiologic variables, for example, by positron emission tomography (PET) are prevented in most instances by their logistic complexity.作者: Diverticulitis 時(shí)間: 2025-3-25 05:16
Calcium Channel Blockers Prevent Delayed Cerebral Ischemia After Intracranial Aneurysmal Subarachnoitracellular messengers and mitochondrial metabolism [31]. Experimental studies of cerebral ischemia in animal models have shown that pretreatment with the calcium entry antagonist nimodipine results in protection of the brain from cerbral infarction by preventing calcium entry into ischemic neurones and glia [1].作者: Disk199 時(shí)間: 2025-3-25 09:04 作者: BOOR 時(shí)間: 2025-3-25 11:44 作者: 時(shí)代錯(cuò)誤 時(shí)間: 2025-3-25 17:38 作者: compose 時(shí)間: 2025-3-25 20:08 作者: 委托 時(shí)間: 2025-3-26 00:24 作者: 復(fù)習(xí) 時(shí)間: 2025-3-26 06:36
W. Ried,B. Jerosch,J. F. Willemstatus are the regulation of intracellular pH (pHj) and calcium (Ca2+j) [6]. For example, a rise in pHj heralds the onset of increased cellular activity while a fall in pHi is associated with a reduction in vital processes in numerous cell types [5]. Furthermore, a rise in Ca.+. is a ubiquitous trigg作者: Peculate 時(shí)間: 2025-3-26 09:31
https://doi.org/10.1007/978-3-662-25231-4d axons. We have been interested in the pathophysiology of CNS axonal injury and have developed a reliable model system for studying the basic mechanisms of injury to CNS-myelinated axons caused by anoxia (Stys et al. 1990a; Ransom et al. 1993). The nonsynaptic ionic mechanisms which are critical in作者: 身心疲憊 時(shí)間: 2025-3-26 15:16
Recovery from Motor Stroke: Different Patterns of Functional Reorganisation in Individual Patientsramidal tract is not completely disrupted, preserved corticospinal tract fibres with a different destination under normal conditions may bypass the interruption of efferent traffic from the motor cortex and may subserve the transport of information for fractionated finger movements to the hand and f作者: 不安 時(shí)間: 2025-3-26 19:52 作者: constitute 時(shí)間: 2025-3-26 21:06
Anoxic Injury of Central Myelinated Axons: Nonsynaptic Ionic Mechanismsd axons. We have been interested in the pathophysiology of CNS axonal injury and have developed a reliable model system for studying the basic mechanisms of injury to CNS-myelinated axons caused by anoxia (Stys et al. 1990a; Ransom et al. 1993). The nonsynaptic ionic mechanisms which are critical in作者: Legend 時(shí)間: 2025-3-27 02:46 作者: 遭受 時(shí)間: 2025-3-27 08:00
Uncoupling of Flow and Metabolism in Early Ischemic Stroketive for different therapeutic approaches: one short period during which improvement of perfusion is successful in reversing functional deficits and preventing morphological damage, and a probably longer period during which the progressive infarction could be ameliorated by intervention with ongoing作者: Motilin 時(shí)間: 2025-3-27 11:20 作者: 并置 時(shí)間: 2025-3-27 14:33
Head Injuries: A Target for Neuroprotection and the increasing frequency with which younger patients are injured. There is evidence from several sources that ischaemic brain damage is the most important component of secondary brain damage either due to cerebral compression, or from poor oxygenation and perfusion, due to post-traumatic lung o作者: Enliven 時(shí)間: 2025-3-27 19:48 作者: padding 時(shí)間: 2025-3-27 21:57
Aspects of Acid-Base Homeostasis in Ischemia damage resulting from inadequate oxygen supply to the brain or head trauma (see Rosner and Becker 1984 for review). Intracellular acidosis has been extensively investigated and nuclear magnetic resonance spectroscopy has provided new insights (Siesjo 1985; Allen et al. 1988), but it is also importa作者: guardianship 時(shí)間: 2025-3-28 03:42 作者: PIZZA 時(shí)間: 2025-3-28 09:06 作者: 勤勞 時(shí)間: 2025-3-28 13:55
In Vivo Nuclear Magnetic Resonance Observation of Cerebral Metabolismlular environment to a greater and greater degree. Position emission tomography (PET) and single photon emission computed tomography (SPECT) have provided important information on cerebral blood flow, metabolism, and receptor distributions. Here we review the recent improvements in nuclear magnetic 作者: Priapism 時(shí)間: 2025-3-28 17:36
Effects of Extracellular Acidosis on Glial Cell Intracellular pH: Evidence for a Glial Spatial H+-Buseizures,, and head injury (Siesjo 1981). A marked decrease in brain tissue pH has been demonstrated in cerebral ischemia - even more so in hyperglycemic subjects - where lactic acid may accumulate to 20–30 mM and higher concentrations (Rehncrona et al. 1980; Katsura et al. 1991). Tissue pH may drop作者: amyloid 時(shí)間: 2025-3-28 18:46
Calcium Channel Blockers Prevent Delayed Cerebral Ischemia After Intracranial Aneurysmal Subarachnoirough endothelial and ischemic neuronal cell membranes [9, 30]. It is well known that when Ca. ions enter vascular smooth muscle, contraction results, but if calcium entry is blocked by calcium antagonists, vascular dilatation occurs. It is also well known that when extracellular Ca2+ moves into isc作者: 終止 時(shí)間: 2025-3-29 00:21
Monosialoganglioside GM1 in Experimental Models of Strokelevels of glutamate accumulate in the interstitial fluid during an ischemic/traumatic episode [3] and, through the activation of ionotropic glutamate receptors, initiate a cascade of cellular events which ultimately lead to irreversible cell damage. These cellular events contributing to excitotoxici作者: 有效 時(shí)間: 2025-3-29 06:27
What Are We Learning from Clinical Trials in Acute Cerebral Ischemia?chemia, such as osmotics, steroids, vasodilators, hemodilution, which have all systematically failed. We would rather not elaborate that discouraging list but think about how to make use of these negative experiences as examples of methodological errors which should not be repeated. Thus, studies wi作者: acquisition 時(shí)間: 2025-3-29 11:15
Threshold of Calcium Influx After Global and Focal Ischemia: Implications for the Window of Therapeuum [13, 14]. Activation of calcium-dependent enzymes such as protein kinase C, calmodulin (CaM) kinase II, calpain I, calcineurin, and phospholipase A2 is believed to play a major role in neuronal excitotoxicity [2, 4, 5, 16]. In addition, therapeutic intervention with agents which target either vol作者: frivolous 時(shí)間: 2025-3-29 12:30 作者: 確認(rèn) 時(shí)間: 2025-3-29 16:12
Oberrheinische Studien Band III but this depends to some extent on the definition of the term; it is useful and less nihilistic to take a broader view. In the past two decades much evidence has accumulated on the many parameters which define this window, or rather these windows.作者: 偉大 時(shí)間: 2025-3-29 20:10
https://doi.org/10.1007/978-3-662-24747-1tive for different therapeutic approaches: one short period during which improvement of perfusion is successful in reversing functional deficits and preventing morphological damage, and a probably longer period during which the progressive infarction could be ameliorated by intervention with ongoing作者: Incise 時(shí)間: 2025-3-30 01:01 作者: locus-ceruleus 時(shí)間: 2025-3-30 07:48 作者: Foam-Cells 時(shí)間: 2025-3-30 08:36 作者: Debate 時(shí)間: 2025-3-30 12:23 作者: multiply 時(shí)間: 2025-3-30 17:38
W. Ried,B. Jerosch,J. F. Willems in the behavior of these cells. Astrocytes are either transformed into so–called “reactive species” after a reduction in blood flow [1, 33], or they are destroyed by the process, along with other brain cell elements [1]. Reactive astrocytosis is a process that may influence mechanisms by which the 作者: 業(yè)余愛好者 時(shí)間: 2025-3-30 22:12 作者: 憂傷 時(shí)間: 2025-3-31 03:32
https://doi.org/10.1007/978-3-662-25234-5lular environment to a greater and greater degree. Position emission tomography (PET) and single photon emission computed tomography (SPECT) have provided important information on cerebral blood flow, metabolism, and receptor distributions. Here we review the recent improvements in nuclear magnetic 作者: 土產(chǎn) 時(shí)間: 2025-3-31 06:09 作者: AMBI 時(shí)間: 2025-3-31 10:37
https://doi.org/10.1007/978-3-662-26794-3rough endothelial and ischemic neuronal cell membranes [9, 30]. It is well known that when Ca. ions enter vascular smooth muscle, contraction results, but if calcium entry is blocked by calcium antagonists, vascular dilatation occurs. It is also well known that when extracellular Ca2+ moves into isc
