作者: 脆弱么 時間: 2025-3-21 22:42 作者: dominant 時間: 2025-3-22 01:05
Deferoxamine reduces brain swelling in a rat model of hippocampal intracerebral hemorrhageorrhage (ICH). There were 2 parts to the experiments in this study. In the first part, male Sprague-Dawley rats received a 10-μL infusion of either packed red blood cells (RBC), lysed RBC, hemoglobin, ferrous iron, or saline, into the hippocampus. In the second part, rats received a 10-μL infusion o作者: Gustatory 時間: 2025-3-22 04:43
The antioxidant effects of melatonin after intracerebral hemorrhage in ratsr and indirect antioxidant, the objective of this study was to evaluate whether melatonin administration would attenuate oxidative stress, brain edema, and neurological deficits in a rat model of ICH. Animals were assigned into groups consisting of sham (needle trauma), vehicle, and melatonin (15 or作者: 使出神 時間: 2025-3-22 10:58
Poly(ADP-ribose) polymerase activation and brain edema formation by hemoglobin after intracerebral hollowing ICH are not well-understood. We have found that hemoglobin plays an important role in edema development after ICH. In this study, we sought to explore the mechanism of brain edema formation caused by hemoglobin..Hemoglobin was infused into the right basal ganglia of male Sprague-Dawley rats作者: EVICT 時間: 2025-3-22 14:22
Induction of autophagy in rat hippocampus and cultured neurons by iron this study, we examined whether iron can induce autophagy in the hippocampus and in cultured neurons..For in vivo studies, rats received an infusion of either saline or ferrous iron into the right hippocampus and were killed 1, 3, or 7 days later for Western blot analysis of microtubule-associated 作者: EVICT 時間: 2025-3-22 18:32
Effects of superoxide dismutase and catalase derivates on intracerebral hemorrhage-induced brain injn injuries, especially those associated with ischemia/ reperfusion. In this study, we investigated effects of these enzymatic antioxidants on intracerebral hemorrhage (ICH)-induced brain injury..A total of 65 male Sprague-Dawley rats (300-380g) were divided into a sham group, an untreated ICH group,作者: 厚顏無恥 時間: 2025-3-22 23:42
Metallothionein and brain injury after intracerebral hemorrhage genomics study has shown that brain MT-1 and MT-2 mRNA levels are upregulated following intracerebral hemorrhage (ICH) in rats. Our study examines whether brain MT-1 and MT-2 protein levels are increased after ICH. We also investigated the effect of exogenous MT-1 in perihematomal edema formation .作者: 橢圓 時間: 2025-3-23 03:22
Intracerebral hemorrhage injury mechanisms: glutamate neurotoxicity, thrombin, and Srcse utilization (LCGU) studies performed to address this issue demonstrate increased LCGU within hours around an ICH that is blocked by NMDA and AMPA glutamate receptor antagonists. Local injections of NMDA or AMPA increased LCGU whereas glutamate did not, suggesting an ICH effect on glutamate uptake作者: 大溝 時間: 2025-3-23 08:33
Increase in brain thrombin activity after experimental intracerebral hemorrhage perihematomal zone and examined the role of thrombin in ICH-induced brain tissue loss..There were 2 experiments in this study. In the first part, adult male Sprague-Dawley rats received 100 μL of either autologous whole blood or saline. The rats were killed at 1 h or 24 h later for thrombin activit作者: fatty-streak 時間: 2025-3-23 12:45
Concomitant intracerebral infusion of tissue plasminogen activator and thrombin leads to brain injurmbin cause brain injury when infused concomitantly with tissue plasminogen activator (tPA), which is used clinically to facilitate evacuation of intracerebral hematomas. In this study, we examined the effects of intracerebral infusion of tPA and thrombin, individually and in combination..Rats were i作者: sperse 時間: 2025-3-23 17:54 作者: Predigest 時間: 2025-3-23 19:33 作者: 退出可食用 時間: 2025-3-23 23:59
Blood-brain barrier function in intracerebral hemorrhagemark of ICH-induced brain injury. Such disruption contributes to edema formation, the influx of leukocytes, and the entry of potentially neuroactive agents into the perihematomal brain, all of which may contribute to brain injury. A range of factors have been implicated in inducing BBB disruption, i作者: Consequence 時間: 2025-3-24 04:50 作者: OREX 時間: 2025-3-24 09:48 作者: interrogate 時間: 2025-3-24 14:16
https://doi.org/10.1007/978-3-662-09482-2aldehyde, and superoxide dismutase, indicating a potent oxidizing environment. BOX concentrations increased from 0.084 ± 0.01 in fresh blood to 22.24 ± 4.28 in hematoma at 72h, and were 11.22 ±1.90 in adjacent white matter (nmol/g). Similar chemical and analytical results are seen in ICH in vivo, in作者: 1分開 時間: 2025-3-24 17:20 作者: esoteric 時間: 2025-3-24 21:03 作者: coddle 時間: 2025-3-25 00:22 作者: 敏捷 時間: 2025-3-25 06:25 作者: APRON 時間: 2025-3-25 08:56 作者: Pamphlet 時間: 2025-3-25 13:00
Oliver Günther,Johannes Lambertsne caused significant neuronal death at days 1 and 3, and resulted in significant brain tissue loss at day 28. These results suggest that thrombin inhibition in the acute phase may reduce ICH-induced brain damage.作者: pellagra 時間: 2025-3-25 16:15
Medullary Tractotomy for Facial Pain,of thrombin + tPA markedly increased Evans blue tissue content in ipsilateral brain samples (. < 0.05). Fluoro-Jade-stained sections from thrombin+ tPA group demonstrated significantly higher cell death counts (. < 0.01). Significant neurological deficit was revealed in thrombin+ tPA group in foreli作者: Initiative 時間: 2025-3-25 22:03 作者: 權宜之計 時間: 2025-3-26 01:21 作者: Kaleidoscope 時間: 2025-3-26 05:51 作者: 序曲 時間: 2025-3-26 10:04 作者: 忍受 時間: 2025-3-26 13:35
Bilirubin oxidation products, oxidative stress, and intracerebral hemorrhagealdehyde, and superoxide dismutase, indicating a potent oxidizing environment. BOX concentrations increased from 0.084 ± 0.01 in fresh blood to 22.24 ± 4.28 in hematoma at 72h, and were 11.22 ±1.90 in adjacent white matter (nmol/g). Similar chemical and analytical results are seen in ICH in vivo, in作者: Indurate 時間: 2025-3-26 20:14
Deferoxamine reduces brain swelling in a rat model of hippocampal intracerebral hemorrhagen swelling (6.14 ± 0.45 vs. 7.11 ± 0.58mm. in the vehicle group, p<0.05). In addition, deferoxamine reduced hemoglobin-induced DNA damage. These results indicate that iron has a key role in hemoglobin-induced brain swelling. Deferoxamine may be a useful treatment for ICH patients.作者: 雪上輕舟飛過 時間: 2025-3-27 00:21
The antioxidant effects of melatonin after intracerebral hemorrhage in ratsoring and brain water content in the right basal ganglia was without significant difference between any treatment regimens (15 or 150mg=kg of melatonin) or time points of drug administration (15 min or 3 h post-ICH). Therefore, melatonin reduced oxidative stress but did not change extent of brain ed作者: 碎片 時間: 2025-3-27 04:33
Induction of autophagy in rat hippocampus and cultured neurons by irong showed an accumulation of MDC in cultured neurons exposed to ferrous iron..These results indicate that autophagy is induced by iron in neurons and that iron-induced autophagy may contribute to brain injury after ICH.作者: FLAT 時間: 2025-3-27 08:17 作者: 無法解釋 時間: 2025-3-27 10:50
Intracerebral hemorrhage injury mechanisms: glutamate neurotoxicity, thrombin, and Srcnd ICH and improved behavioral function following ICH. This data leads us to suggest our hypothesis, that ICH, possibly via thrombin activation of protease-activated receptors, activates Src that phosphorylates NMDA receptors and other proteins that mediate injury after ICH.作者: Oratory 時間: 2025-3-27 16:31
Increase in brain thrombin activity after experimental intracerebral hemorrhagene caused significant neuronal death at days 1 and 3, and resulted in significant brain tissue loss at day 28. These results suggest that thrombin inhibition in the acute phase may reduce ICH-induced brain damage.作者: cunning 時間: 2025-3-27 19:01 作者: 使習慣于 時間: 2025-3-27 23:16 作者: 譏笑 時間: 2025-3-28 02:12 作者: diathermy 時間: 2025-3-28 08:45 作者: alabaster 時間: 2025-3-28 13:56
Treatment of stroke and intracerebral hemorrhage with cellular and pharmacological restorative therahis endogenous restorative brain plasticity process to potentiate functional recovery. The logic of restorative therapy is to treat intact or marginally compromised tissue and not injured or dying tissue. Thus, these treatments can be made available for all neurological injury. Once demonstrated to 作者: 修正案 時間: 2025-3-28 15:34
Cerebral Hemorrhage978-3-211-09469-3Series ISSN 0065-1419 Series E-ISSN 2197-8395 作者: Dawdle 時間: 2025-3-28 19:15
Liang-Fu Zhou,Xian-Cheng Chen,Yi-Cheng LuIncludes supplementary material: 作者: spinal-stenosis 時間: 2025-3-28 23:10
Acta Neurochirurgica Supplementhttp://image.papertrans.cn/c/image/223301.jpg作者: 發(fā)微光 時間: 2025-3-29 05:51
,Klassen und Instanzen — Der Rechner lebt!,role in ICH-induced brain injury. Iron overload occurs in the brain after ICH in rats. Intracerebral infusion of iron causes brain edema and neuronal death..Deferoxamine, an iron chelator, is an FDA-approved drug for the treatment of acute iron intoxication and chronic iron overload due to transfusi作者: Semblance 時間: 2025-3-29 08:56
https://doi.org/10.1007/978-3-662-09482-2ons. We report facile production of bilirubin oxidation products (BOXes) via hemoglobin=Fenton reaction under conditions approximating putative in vivo conditions seen following ICH..Using a mixture of human hemoglobin, physiological buffers, uncon-jugated solubilized bilirubin, and molecular oxygen作者: GENUS 時間: 2025-3-29 11:45
Tonny A. Springer,Ferdinand D. Veldkamporrhage (ICH). There were 2 parts to the experiments in this study. In the first part, male Sprague-Dawley rats received a 10-μL infusion of either packed red blood cells (RBC), lysed RBC, hemoglobin, ferrous iron, or saline, into the hippocampus. In the second part, rats received a 10-μL infusion o作者: defuse 時間: 2025-3-29 16:06
Tonny A. Springer,Ferdinand D. Veldkampr and indirect antioxidant, the objective of this study was to evaluate whether melatonin administration would attenuate oxidative stress, brain edema, and neurological deficits in a rat model of ICH. Animals were assigned into groups consisting of sham (needle trauma), vehicle, and melatonin (15 or作者: 單獨 時間: 2025-3-29 22:42 作者: 綁架 時間: 2025-3-30 00:41
https://doi.org/10.1007/978-3-662-12627-1 this study, we examined whether iron can induce autophagy in the hippocampus and in cultured neurons..For in vivo studies, rats received an infusion of either saline or ferrous iron into the right hippocampus and were killed 1, 3, or 7 days later for Western blot analysis of microtubule-associated 作者: OUTRE 時間: 2025-3-30 06:44 作者: Interferons 時間: 2025-3-30 08:34
Exchange Rate Policy in Eastern Europe genomics study has shown that brain MT-1 and MT-2 mRNA levels are upregulated following intracerebral hemorrhage (ICH) in rats. Our study examines whether brain MT-1 and MT-2 protein levels are increased after ICH. We also investigated the effect of exogenous MT-1 in perihematomal edema formation .作者: nonradioactive 時間: 2025-3-30 15:09
Oliver Günther,Johannes Lambertsse utilization (LCGU) studies performed to address this issue demonstrate increased LCGU within hours around an ICH that is blocked by NMDA and AMPA glutamate receptor antagonists. Local injections of NMDA or AMPA increased LCGU whereas glutamate did not, suggesting an ICH effect on glutamate uptake作者: Lineage 時間: 2025-3-30 17:33
Oliver Günther,Johannes Lamberts perihematomal zone and examined the role of thrombin in ICH-induced brain tissue loss..There were 2 experiments in this study. In the first part, adult male Sprague-Dawley rats received 100 μL of either autologous whole blood or saline. The rats were killed at 1 h or 24 h later for thrombin activit作者: 基因組 時間: 2025-3-31 00:13
Medullary Tractotomy for Facial Pain,mbin cause brain injury when infused concomitantly with tissue plasminogen activator (tPA), which is used clinically to facilitate evacuation of intracerebral hematomas. In this study, we examined the effects of intracerebral infusion of tPA and thrombin, individually and in combination..Rats were i作者: Exploit 時間: 2025-3-31 03:42
Falx and Parasagittal Meningiomas,interleukin-1 beta (IL-1β) are 2 major proinflammatory cytokines. In this study, we investigated whether thrombin stimulates TNF-a and IL-1β secretion ., and whether microglial inhibition reduces ICH-induced brain injury ...There were 2 parts to this study. In the first part, cultured rat microglial作者: Munificent 時間: 2025-3-31 08:35
https://doi.org/10.1007/978-3-662-12637-0utrophil infiltration contribute to brain injury after ICH. In this study, we investigated the effects of aging on activation of the complement cascade and neutrophil influx following ICH..Male Sprague-Dawley rats (3 or 18 months old) received an infusion of 100 mL autologous blood into right caudat作者: armistice 時間: 2025-3-31 09:35
Symphyse und obere Schambein?stemark of ICH-induced brain injury. Such disruption contributes to edema formation, the influx of leukocytes, and the entry of potentially neuroactive agents into the perihematomal brain, all of which may contribute to brain injury. A range of factors have been implicated in inducing BBB disruption, i作者: 記憶法 時間: 2025-3-31 16:13 作者: BOLUS 時間: 2025-3-31 19:15
