標(biāo)題: Titlebook: Centenarians; An Example of Positi Calogero Caruso Book 2019 Springer Nature Switzerland AG 2019 Aging.Longevity.Phenotype.Genetics.Epigene [打印本頁(yè)] 作者: corrupt 時(shí)間: 2025-3-21 19:05
書(shū)目名稱Centenarians影響因子(影響力)
作者: 脆弱吧 時(shí)間: 2025-3-21 23:31
http://image.papertrans.cn/c/image/223141.jpg作者: 友好 時(shí)間: 2025-3-22 02:28
https://doi.org/10.1007/978-3-642-45616-9le. This renders the studies of the processes involved in longevity, a complex process influenced by several biological, environmental, and lifestyle factors as well as by chance, of critical importance. Centenarians have been proposed as a model of “positive biology” because they have reached the e作者: Jargon 時(shí)間: 2025-3-22 05:55
https://doi.org/10.1007/978-3-642-45711-1it necessary to identify a good strategy to reach healthy ageing and avoid or delay age-related diseases. The longevity phenotype is the result of a positive combination between genetic, epigenetic, stochastic and lifestyle factors. So, the analysis of all the known parameters that can influence the作者: GRUEL 時(shí)間: 2025-3-22 09:11 作者: 舊式步槍 時(shí)間: 2025-3-22 13:45 作者: 舊式步槍 時(shí)間: 2025-3-22 20:42 作者: MUT 時(shí)間: 2025-3-22 22:38 作者: Water-Brash 時(shí)間: 2025-3-23 03:30 作者: RACE 時(shí)間: 2025-3-23 08:01 作者: 施魔法 時(shí)間: 2025-3-23 12:35 作者: placebo 時(shí)間: 2025-3-23 16:11 作者: 鑲嵌細(xì)工 時(shí)間: 2025-3-23 20:11
978-3-030-20764-9Springer Nature Switzerland AG 2019作者: 可憎 時(shí)間: 2025-3-23 22:47 作者: Delude 時(shí)間: 2025-3-24 02:41 作者: Deceit 時(shí)間: 2025-3-24 09:03 作者: Flustered 時(shí)間: 2025-3-24 13:19
Chance and Causality in Ageing and Longevity,xtreme limits of lifespan, avoiding or delaying major age-related diseases. The identification of the factors that predispose to long and healthy life is of tremendous interest for translational medicine. Here we briefly describe the results obtained so far and their meaning, focusing on the role of chance and causality.作者: 行乞 時(shí)間: 2025-3-24 17:27 作者: 半身雕像 時(shí)間: 2025-3-24 21:56
Genetic Signatures of Centenarians,tudy and back to the case–control study with SNPs array, imputation and whole genome sequencing. Results were analysed either independently or by combining different cohorts through meta-analysis. Furthermore, genetic signatures were identified that predict the phenotypic outcome of exceptional long-living individuals.作者: exacerbate 時(shí)間: 2025-3-25 01:01
https://doi.org/10.1007/978-3-642-45711-1 mechanisms involved in the pathogenesis of age-related diseases, as the pro- and anti-inflammatory pathways or the pro- and antioxidant systems and their contribution, are crucial to this aim. Moreover, the psychological and cognitive aspects must be taken into account. In this chapter, to understa作者: 要控制 時(shí)間: 2025-3-25 06:48 作者: 玉米棒子 時(shí)間: 2025-3-25 07:35
https://doi.org/10.1007/978-3-642-45711-1ument to accurately establish the relative risk of developing cardiovascular, metabolic and oncological diseases, taking into account not only the inflammatory power of foods but also the coadjuvant pathogenetic role of ageing in favouring the development of these pathologies. Furthermore, it is als作者: Overstate 時(shí)間: 2025-3-25 13:55 作者: 平項(xiàng)山 時(shí)間: 2025-3-25 16:20
https://doi.org/10.1007/978-3-642-45726-5lomere shortening, likely because they increase DNA damage through oxidative stress. Recently, studies have identified lifestyle factors that can potentially protect telomeres. For example, people who lead a healthy lifestyle by increasing their physical activity, practising meditation, adhering to 作者: 使長(zhǎng)胖 時(shí)間: 2025-3-25 21:31 作者: 泛濫 時(shí)間: 2025-3-26 03:57 作者: Intervention 時(shí)間: 2025-3-26 06:24
Book 2019g, the related diseases, and longevity are difficult to define as a consequence of causality, chance or both. Discussing the relevance of these different factors in the attainment of longevity, the book gathers contributions on genetic, epigenetic and phenotypic aspects of centenarians..The “positiv作者: Generic-Drug 時(shí)間: 2025-3-26 09:16 作者: multiply 時(shí)間: 2025-3-26 16:26 作者: 暫時(shí)中止 時(shí)間: 2025-3-26 18:09
,Centenarian Offspring as a?Model of Successful Ageing,how a very healthy status and a good cardiovascular and immunological profile, like their parents. Unlike the centenarians, they are a large group and can be studied by comparison with age-matched controls to perform accurate investigations on genetic and environmental determinants of healthy ageing作者: Limited 時(shí)間: 2025-3-26 20:58 作者: 權(quán)宜之計(jì) 時(shí)間: 2025-3-27 01:06
Epigenetics and Ageing,en considered as a bridge between genome and environment in the definition of phenotype (Norouzitallab et al., Sci Total Environ 647:1281–1293, 2018). Many evidences have suggested in the last decade that ageing, which is deeply influenced by genetics, environment and their interaction, may be influ作者: 損壞 時(shí)間: 2025-3-27 09:22
Lifestyle Choices, Psychological Stress and Their Impact on Ageing: The Role of Telomeres,lomere shortening, likely because they increase DNA damage through oxidative stress. Recently, studies have identified lifestyle factors that can potentially protect telomeres. For example, people who lead a healthy lifestyle by increasing their physical activity, practising meditation, adhering to 作者: Prologue 時(shí)間: 2025-3-27 12:20 作者: flex336 時(shí)間: 2025-3-27 14:05
,Lifespan and Healthspan Extension by?Nutraceuticals: An Overview,mental model organisms. We also highlight the potential ability of nutraceuticals to extend the healthy years in humans, encouraging more in-depth and well-controlled clinical and epidemiological studies to better define the potential healthspan-promoting effects of these compounds.作者: 連接 時(shí)間: 2025-3-27 21:43 作者: 寬度 時(shí)間: 2025-3-27 22:58 作者: 勤勉 時(shí)間: 2025-3-28 03:19 作者: 假 時(shí)間: 2025-3-28 09:21 作者: 象形文字 時(shí)間: 2025-3-28 12:26
Genetic Signatures of Centenarians,me ages. The challenge, since the beginning of the 1990s, was the identification of the genetic variants that predispose these individuals to avoid diseases of ageing and live long and healthy lives. Genetic approaches (study design) were adopted based on the available platforms. Indeed, entrepreneu作者: 總 時(shí)間: 2025-3-28 15:11
Epigenetics and Ageing,e expression and the activity of genes (Armstrong, Epigenetics, Garland Science, New York, 2013; Pinel et al., BioSocieties 13:276–303, 2018). In fact, DNA methylation and histone modification, that are covalent and non-covalent modifications of DNA and histone proteins, alter DNA accessibility and 作者: Heretical 時(shí)間: 2025-3-28 18:51
Lifestyle Choices, Psychological Stress and Their Impact on Ageing: The Role of Telomeres,ing with increasing age is a part of the normal ageing process. However, factors such as inflammation, oxidative stress and other genotoxic stressors may also increase the rate of telomere attrition, leading to telomere dysfunction-mediated cellular senescence and accelerating the ageing process. On作者: FAZE 時(shí)間: 2025-3-29 00:22 作者: 殺菌劑 時(shí)間: 2025-3-29 04:52
