標(biāo)題: Titlebook: Cellular Drug Delivery; Principles and Pract D. Robert Lu,Svein ?ie Book 2004 Springer Science+Business Media New York 2004 biology.cancer. [打印本頁(yè)] 作者: bankrupt 時(shí)間: 2025-3-21 17:10
書目名稱Cellular Drug Delivery影響因子(影響力)
書目名稱Cellular Drug Delivery影響因子(影響力)學(xué)科排名
書目名稱Cellular Drug Delivery網(wǎng)絡(luò)公開(kāi)度
書目名稱Cellular Drug Delivery網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書目名稱Cellular Drug Delivery被引頻次
書目名稱Cellular Drug Delivery被引頻次學(xué)科排名
書目名稱Cellular Drug Delivery年度引用
書目名稱Cellular Drug Delivery年度引用學(xué)科排名
書目名稱Cellular Drug Delivery讀者反饋
書目名稱Cellular Drug Delivery讀者反饋學(xué)科排名
作者: cortex 時(shí)間: 2025-3-21 21:39
Cellular Structure, Function, and Membrane Transportal active ingredients to elucidating the biological mechanisms of site-specific interactions, the science of cellular drug delivery is a complex, integral part of the treatment and prevention of life-threatening illnesses. Every year, new information is made available from many different research ar作者: deceive 時(shí)間: 2025-3-22 02:31 作者: fleeting 時(shí)間: 2025-3-22 07:06
Augmentation of Cell-Mediated Immunity to Virustibody responses, viral infection may require additional defense mechanisms known as cell-mediated immunity. Unlike bacteria and fungi, virus replication requires host-cell machinery, including mechanisms of DNA, RNA, and protein synthesis. Therefore, after initial viral infection of host cells and 作者: FADE 時(shí)間: 2025-3-22 11:48
Development of Nonviral DNA Delivery Systems established antiviral immunity in many patients and the rapid induction of an adaptive immune response in na?ve patients continues to block many attempts to introduce DNA by viral vectors. Nonviral delivery strategies avoid the problems of viral-coat proteins, but encountered new challenges of low 作者: biosphere 時(shí)間: 2025-3-22 16:08
Nucleic Acid Cellular Delivery generated much enthusiasm from researchers and the lay public. Even though the potential for medical advances exists, there are still obstacles that must be overcome before this gene-therapy paradigm becomes a viable option. One of the more substantial obstacles is the delivery vector for the nucle作者: biosphere 時(shí)間: 2025-3-22 20:45
TAT and TAT-Like Peptides for Protein Transduction and Intracellular Drug Deliverynological breakthroughs such as combinatorial chemistry, computer-assisted drug design, robotic screening, and molecular cloning have made thousands of small compounds and macromolecules such as proteins and nucleic acids available for therapeutic consideration. Despite this progress, two major obst作者: MAG 時(shí)間: 2025-3-22 21:20
Carrier-Mediated Mechanisms for Cellular Drug Transportntry of nutrients; facilitate uptake and release of hormones, neurotransmitters, and various signaling molecules; participate in transfer of nucleic acids across the cell membrane; and participate in secretion of proteins, lipids, and carbohydrates into and beyond the cytoplasmic membrane. These mem作者: jarring 時(shí)間: 2025-3-23 03:43 作者: 不確定 時(shí)間: 2025-3-23 08:57 作者: intertwine 時(shí)間: 2025-3-23 10:50
Targeted Drug Delivery to Tumor Cells Using Colloidal Carriersanticancer drugs and genes. Tumors are an uncontrolled mass of proliferations of a single malignant cell arising from mutations, which are either inherited or caused by environmental factors .. In order to reach the tumor cells, systemically administered drugs have to overcome a number of obstacles,作者: Traumatic-Grief 時(shí)間: 2025-3-23 14:18
Biological Protein Nanostructures and Targeted Drug Deliverylar complexes or organelles within a cell while avoiding drug loading in nontargeted cells. Targeted delivery of drugs to specific cells involves the specific interactions between drugs or drug carriers and the cell-surface proteins through ligand—receptor interactions or antigen—antibody interactio作者: 我的巨大 時(shí)間: 2025-3-23 20:37
Formulation Considerations for DNA-Based Therapeuticscurrently considered incurable, e.g., cancer, cystic fibrosis (CF), severe combined immunodeficiency (SCID), and acquired immune deficiency syndrome (AIDS) .. Considering the tremendous promise of DNA-delivery technology, in addition to the extensive genetic information now available from the Human 作者: Microaneurysm 時(shí)間: 2025-3-23 23:56
Cationic Microparticles and Emulsions As Effective Delivery Systems for Immune Stimulatory CpG DNAeviously .. However, the particles used in early studies were nondegradable and therefore, were not appropriate for development as vaccine adjuvants for human use. In addition, antigens were often chemically conjugated to the nondegradable particles, adding an extra level of complexity and making co作者: 壓碎 時(shí)間: 2025-3-24 04:45 作者: Mechanics 時(shí)間: 2025-3-24 10:11 作者: 招惹 時(shí)間: 2025-3-24 13:54
https://doi.org/10.1007/978-3-322-97110-4e of the global market has been more than 10%. The large market size allows big pharmaceutical companies to invest heavily in research and development (R&D). In 2002 alone, the combined R&D budget of Pfizer, Pharmacia, Merck, Eli Lilly, and Bristol-Myers Squibb was more than $16 billion. Despite an 作者: debris 時(shí)間: 2025-3-24 15:43
Die Darstellung organisierter Interessenal active ingredients to elucidating the biological mechanisms of site-specific interactions, the science of cellular drug delivery is a complex, integral part of the treatment and prevention of life-threatening illnesses. Every year, new information is made available from many different research ar作者: gangrene 時(shí)間: 2025-3-24 21:52 作者: Arroyo 時(shí)間: 2025-3-25 01:43 作者: Humble 時(shí)間: 2025-3-25 07:11
https://doi.org/10.1007/978-3-322-97216-3 established antiviral immunity in many patients and the rapid induction of an adaptive immune response in na?ve patients continues to block many attempts to introduce DNA by viral vectors. Nonviral delivery strategies avoid the problems of viral-coat proteins, but encountered new challenges of low 作者: Anthrp 時(shí)間: 2025-3-25 07:46 作者: grandiose 時(shí)間: 2025-3-25 14:59 作者: 巨碩 時(shí)間: 2025-3-25 16:41
Der lange Weg vom DDR- zum Bundesbürgerntry of nutrients; facilitate uptake and release of hormones, neurotransmitters, and various signaling molecules; participate in transfer of nucleic acids across the cell membrane; and participate in secretion of proteins, lipids, and carbohydrates into and beyond the cytoplasmic membrane. These mem作者: agglomerate 時(shí)間: 2025-3-25 21:00
Zur Mentalit?t der ostdeutschen Jugend of structurally unrelated large lipophilic compounds from the cell, providing what is often known as multiple drug resistance (MDR) .. MDR is characterized by active efflux or pumping of xenobiotics and pharmaceuticals via transmembrane proteins acting as hydrophobic “vacuum cleaners” .,.. The MDR1作者: Brain-Waves 時(shí)間: 2025-3-26 00:10
Der lange Weg vom DDR- zum Bundesbürgerrally the case, even when the site of drug action is beyond the gastrointestinal tract (GI), requiring the drug to be systemically available. For systemic drug availability, drug dosing via the oral route requires the drug to exhibit sufficient gastrointestinal absorption. Two components of drug abs作者: 展覽 時(shí)間: 2025-3-26 06:20 作者: faddish 時(shí)間: 2025-3-26 11:37
https://doi.org/10.1007/978-3-322-97626-0lar complexes or organelles within a cell while avoiding drug loading in nontargeted cells. Targeted delivery of drugs to specific cells involves the specific interactions between drugs or drug carriers and the cell-surface proteins through ligand—receptor interactions or antigen—antibody interactio作者: 排斥 時(shí)間: 2025-3-26 16:40
https://doi.org/10.1007/978-3-322-97664-2currently considered incurable, e.g., cancer, cystic fibrosis (CF), severe combined immunodeficiency (SCID), and acquired immune deficiency syndrome (AIDS) .. Considering the tremendous promise of DNA-delivery technology, in addition to the extensive genetic information now available from the Human 作者: construct 時(shí)間: 2025-3-26 20:09 作者: 不透氣 時(shí)間: 2025-3-27 00:29
Literaturwissenschaft / Kulturwissenschaftes or gene transcripts involved in pathogenesis. Several clinical trials have demonstrated the therapeutic value and low toxicity of ODNs .. Because ODNs, like most biopharmaceuticals, are highly susceptible to degradation in the gastrointestinal environment and only poorly absorbed through biomembr作者: 共棲 時(shí)間: 2025-3-27 01:28
Literaturwissenschaft / Kulturwissenschaftpproaches: (1) an antigen- or epitope-based strategy, designed to influence the immune system by interaction with lymphocytes that express only receptors specific for such antigens (e.g., vaccines); or (2) the use of agents that decrease or increase immunity by acting via nonantigen specific recepto作者: Offensive 時(shí)間: 2025-3-27 05:54
https://doi.org/10.1007/978-1-59259-745-1biology; cancer; cancer therapy; delivery; development; drug; drug delivery; drug resistance; future; researc作者: eustachian-tube 時(shí)間: 2025-3-27 12:27 作者: 射手座 時(shí)間: 2025-3-27 15:22 作者: 結(jié)合 時(shí)間: 2025-3-27 20:31 作者: Migratory 時(shí)間: 2025-3-28 01:28
Carrier-Mediated Mechanisms for Cellular Drug Transportbrane-transport proteins also represent key targets for therapeutic applications. Implementation of membrane transporters as therapeutic targets for drug delivery requires an understanding of their normal physiological role and the means by which they recognize ligands at the molecular level.作者: 裝勇敢地做 時(shí)間: 2025-3-28 03:37 作者: HEAVY 時(shí)間: 2025-3-28 09:14 作者: 改變 時(shí)間: 2025-3-28 12:57 作者: Benzodiazepines 時(shí)間: 2025-3-28 15:36 作者: 無(wú)彈性 時(shí)間: 2025-3-28 20:52
Literaturwissenschaft / Kulturwissenschaftluenced in a manner depending on antigen-specific recognition. This finding, combined with advances in target discovery and validation catalyzed by the elucidation of the human genetic map, has resulted in an unprecedented world-wide effort in designing safer drugs or therapeutic strategies that give the concept of vaccination a new meaning.作者: 商業(yè)上 時(shí)間: 2025-3-29 02:06
Human Intestinal Cellular Characteristics and Drug Permeabilitymphasis on the enterocyte and the in vitro Caco-2 cell model. Included is a discussion of the lipid plasma membrane, in vitro drug permeability and its relation to in vivo permeability, and a discussion of future research directions.作者: largesse 時(shí)間: 2025-3-29 03:42 作者: 賞錢 時(shí)間: 2025-3-29 09:35 作者: 挑剔小責(zé) 時(shí)間: 2025-3-29 14:27
https://doi.org/10.1007/978-3-322-97228-6t of drug-delivery systems because of their poly anionic nature and their lack of resistance to metabolic degradation. Historically, the major theme in the design of modern nucleic acid delivery systems is to mimic the viral method of nucleic acid transfer.作者: 有權(quán) 時(shí)間: 2025-3-29 17:58 作者: 參考書目 時(shí)間: 2025-3-29 20:39
https://doi.org/10.1007/978-3-322-97626-0mplexes to lead to the therapeutic effect. In the biological systems, these interactions generally occur on various types of biological nanostructures of protein origin. Understanding and utilization of these biological nanostructures could lead to significant improvement in drug targeting and drug carriers.作者: Nonthreatening 時(shí)間: 2025-3-30 01:58 作者: Instinctive 時(shí)間: 2025-3-30 04:22
Nucleic Acid Cellular Deliveryt of drug-delivery systems because of their poly anionic nature and their lack of resistance to metabolic degradation. Historically, the major theme in the design of modern nucleic acid delivery systems is to mimic the viral method of nucleic acid transfer.作者: 大包裹 時(shí)間: 2025-3-30 09:37
Targeted Drug Delivery to Tumor Cells Using Colloidal Carriersistration to the tumor cells, drug resistance, and toxicity of the anticancer drugs to normal cells .. The high interstitial pressure and absence of lymphatic drainage were also reported to cause problems in distribution of the drug in the solid tumor ..作者: 犬儒主義者 時(shí)間: 2025-3-30 13:09 作者: AWL 時(shí)間: 2025-3-30 20:21
cellular level. On the principles side, the authors discuss the broad spectrum of cellular delivery, ranging from coverage of cell-mediated immunity, gene delivery, and protein targeting, to cellular drug transport, cellular drug permeability, and a variety of carrier system related to targeted drug作者: 失眠癥 時(shí)間: 2025-3-30 20:58
Was sind ?Organisierte Interessen“?on is known as the cell cycle, which involves four major events: cell growth, DNA replication, chromosome segregation into two identical sets, and cell division. The entire process can be divided into two fundamental parts: interphase (including G., S, G2 phases) and mitosis (M phase) ., as illustrated in Fig. 1.作者: seduce 時(shí)間: 2025-3-31 02:25 作者: Slit-Lamp 時(shí)間: 2025-3-31 08:00
Book 2004 authors discuss the broad spectrum of cellular delivery, ranging from coverage of cell-mediated immunity, gene delivery, and protein targeting, to cellular drug transport, cellular drug permeability, and a variety of carrier system related to targeted drug delivery. On the practice side, the author作者: Mawkish 時(shí)間: 2025-3-31 12:50 作者: 新陳代謝 時(shí)間: 2025-3-31 15:57 作者: 相符 時(shí)間: 2025-3-31 18:05 作者: Alveoli 時(shí)間: 2025-3-31 22:17
Cellular Structure, Function, and Membrane Transportbrane structure, transport inside the cell, passive transport through the membranes, and other membrane properties are discussed in Subheading 2, as well as how these membranes serve as a major barrier to the drug-delivery process. Finally, Subheading 3 describes receptor proteins, how they function作者: chapel 時(shí)間: 2025-4-1 03:10 作者: stratum-corneum 時(shí)間: 2025-4-1 06:18
TAT and TAT-Like Peptides for Protein Transduction and Intracellular Drug Delivery that are hydrophilic and those of high molecular weight, to pass through the cell membrane and enter cells. The cell membrane imposes a significant physical barrier to the entrance of drug molecules into cells. The current strategy for overcoming the first obstacle is to develop drugs that are cell
