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標(biāo)題: Titlebook: Cell Impairment in Aging and Development; Vincent J. Cristofalo,Emma Hole?ková Book 1975 The Editor(s) (if applicable) and The Author(s), [打印本頁]

作者: charity    時間: 2025-3-21 17:30
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作者: 首創(chuàng)精神    時間: 2025-3-21 23:50
https://doi.org/10.1007/b100384mparatively more attention has been directed towards the limited division potential of human fibroblasts than to limits in specific functional capability of this or other cell types with time in culture (1). This may be understandable when one considers the dearth of information concerning factors,
作者: tangle    時間: 2025-3-22 03:29

作者: 網(wǎng)絡(luò)添麻煩    時間: 2025-3-22 04:53

作者: 失望未來    時間: 2025-3-22 11:38

作者: Antioxidant    時間: 2025-3-22 13:03

作者: Antioxidant    時間: 2025-3-22 17:38

作者: 重疊    時間: 2025-3-23 00:38
https://doi.org/10.1007/b100384 shown age-associated increases in glycogen content (1), lipid synthesis (2), lipid content (3), the number of lysosomes (4,5) and the specific activities of lysosomal enzymes (6–8). In addition, age related decreases in the specific activities of transketolase and 6-phosphogluconate dehydrogenase h
作者: chuckle    時間: 2025-3-23 02:09

作者: Conquest    時間: 2025-3-23 06:16
G. Bosco,A. Carena,V. Curri,P. Poggioliniotype. Conversely, abnormal cells survive indefinately (1). Several biochemical parameters have been studied in the past 10 years though very few of those studied have dealt with cell-surface integrity (2). However it is feasible to conceive that modifications of cell surface components would impair
作者: 舉止粗野的人    時間: 2025-3-23 09:51

作者: fodlder    時間: 2025-3-23 17:13

作者: aqueduct    時間: 2025-3-23 20:13
Optical Networks and Technologies in various neuromuscular diseases. In some of them, as in Duchenne myopathy, its activity is significantly increased (1). In human tissues, the highest activity was found in muscle, heart and brain. Very low activity was detected in uterus, gall bladder, pylorus, adrenal and thyroid glands (2) and
作者: 可轉(zhuǎn)變    時間: 2025-3-24 02:07
Andrea Spaccapietra,Giovanni Razzettaet al. (1) and Moore et al.(2) a great number of lymphoblastoid lines have been derived. With the aim of contributing to the clarification of this problem a study was conducted of five long-term suspension cultures of leukocytes established in our laboratory from different material. These lines are
作者: insidious    時間: 2025-3-24 06:15

作者: CAMP    時間: 2025-3-24 08:09
Schahram Dustdar,Stephan Haslingeran be tested by comparing cells from the crypts and different levels on the villus in the small intestine. We know from the work of Lesher’s group (1) that the transit time from crypt base to villus tip in the mouse jejunum is just over 50 hr in both 1-year-old and 2 1/2-year-old animals, of which a
作者: Vsd168    時間: 2025-3-24 12:23
Anna Francesca Pattaro,Francesco Schiavone biophysical changes, which occur during the life-span of an individual. These changes are arranged into changes during prenatal development, postnatal development, adolescence and senescence. Ageing takes place at different levels; at the level of the organism, organ and tissue, which includes cell
作者: eucalyptus    時間: 2025-3-24 15:28
https://doi.org/10.1007/978-1-4757-0731-1aging; attention; bone; cell; cells; development; fat; kidney; retina; tissue; tumor
作者: Insatiable    時間: 2025-3-24 19:27

作者: GLARE    時間: 2025-3-25 01:21

作者: 可轉(zhuǎn)變    時間: 2025-3-25 05:27
Cell Impairment in Aging and Development978-1-4757-0731-1Series ISSN 0065-2598 Series E-ISSN 2214-8019
作者: 中世紀(jì)    時間: 2025-3-25 09:11
https://doi.org/10.1007/b100384evidence indicates that it may be possible to use cultured cells as an . model system for cellular aging, several critical questions need to be resolved before any true parallel can be drawn between the . phenomenon and the . process.
作者: wall-stress    時間: 2025-3-25 12:35

作者: transplantation    時間: 2025-3-25 17:05

作者: bile648    時間: 2025-3-25 23:25

作者: Meditate    時間: 2025-3-26 04:10
Time-Lapse Cinemicrophotographic Studies of Cell Division Patterns of Human Diploid Fibroblasts (WIes to study aging at the cellular level. The decline in proliferative capacity of diploid fibroblasts with increasing . age has been attributed to a gradual increase in the proportion of non-dividing cells (3,4,5,8).
作者: 清澈    時間: 2025-3-26 04:57
Creatinephosphokinase in Human Diploid Cell Lines, in various neuromuscular diseases. In some of them, as in Duchenne myopathy, its activity is significantly increased (1). In human tissues, the highest activity was found in muscle, heart and brain. Very low activity was detected in uterus, gall bladder, pylorus, adrenal and thyroid glands (2) and lung.
作者: 過時    時間: 2025-3-26 09:46
Springer Series in Optical SciencesSeveral years ago, during the course of our studies on lysosomes in aging human diploid cells, we observed a small but consistent increase in the lifespan of cultures grown in the presence of 14μM hydrocortisone (HC).
作者: gastritis    時間: 2025-3-26 13:56

作者: 粘    時間: 2025-3-26 18:12
The Effect of Hydrocortisone on DNA Synthesis and Cell Division during Aging ,,Several years ago, during the course of our studies on lysosomes in aging human diploid cells, we observed a small but consistent increase in the lifespan of cultures grown in the presence of 14μM hydrocortisone (HC).
作者: monogamy    時間: 2025-3-26 23:32

作者: Bernstein-test    時間: 2025-3-27 04:29

作者: 尊敬    時間: 2025-3-27 07:28

作者: 熱心    時間: 2025-3-27 13:27
,Do Hyperplastoid Cell Lines “Differentiate Themselves to Death”?,the case of human diploid somatic cells, it is probable that some thousands of such clones have been followed in many different laboratories and to the best of our knowledge, all of them eventually stop growing, unless they are induced to undergo malignant transformation. Curiously, much less is kno
作者: 油氈    時間: 2025-3-27 17:20
,On the Ageing of Intermitotic Cells — Investigations on Enterocytes and Hepatocytes,ofuscin, mitochondria, lysosomes, molecular arrangements between DNA and histones, contents of RNA and pattern of enzymes. But it is questionable up to now: Is there an ageing process of intermitotic cells too? At first we have to distinguish between ageing processes starting in single cells and suc
作者: 漂泊    時間: 2025-3-27 19:54
Springer Series in Optical Sciencesent cell types and the effects of ageing on disease processes. Perhaps the most obvious omission is that of a session primarily concerned with the molecular basis of ageing. It seems to me that the time has come for us to change the title of our group, to the ECBO Study Group on cell and molecular m
作者: GENRE    時間: 2025-3-28 01:06
https://doi.org/10.1007/b100384the case of human diploid somatic cells, it is probable that some thousands of such clones have been followed in many different laboratories and to the best of our knowledge, all of them eventually stop growing, unless they are induced to undergo malignant transformation. Curiously, much less is kno
作者: Frequency-Range    時間: 2025-3-28 04:39
Anna Francesca Pattaro,Francesco Schiavoneofuscin, mitochondria, lysosomes, molecular arrangements between DNA and histones, contents of RNA and pattern of enzymes. But it is questionable up to now: Is there an ageing process of intermitotic cells too? At first we have to distinguish between ageing processes starting in single cells and suc
作者: Metamorphosis    時間: 2025-3-28 08:11

作者: FID    時間: 2025-3-28 14:21
,Cell Ageing: Chairman’s Introduction,s which led to the formation of the group took place here at an earlier meeting organised by Dr. Hole?kova in 1969. This was followed by a meeting in Norwich (U.K.) in 1972. A comparison of the programme of today’s meeting with those of the two earlier meetings is instructive in that it gives a guid
作者: 羅盤    時間: 2025-3-28 15:33

作者: MUMP    時間: 2025-3-28 19:47

作者: triptans    時間: 2025-3-29 00:53

作者: 使顯得不重要    時間: 2025-3-29 03:27

作者: prosthesis    時間: 2025-3-29 08:27
Time-Lapse Cinemicrophotographic Studies of Cell Division Patterns of Human Diploid Fibroblasts (WIes to study aging at the cellular level. The decline in proliferative capacity of diploid fibroblasts with increasing . age has been attributed to a gradual increase in the proportion of non-dividing cells (3,4,5,8).
作者: 你敢命令    時間: 2025-3-29 13:32

作者: 可耕種    時間: 2025-3-29 17:54
Alterations in Chromatin Functions during Aging ,, shown age-associated increases in glycogen content (1), lipid synthesis (2), lipid content (3), the number of lysosomes (4,5) and the specific activities of lysosomal enzymes (6–8). In addition, age related decreases in the specific activities of transketolase and 6-phosphogluconate dehydrogenase h
作者: Mast-Cell    時間: 2025-3-29 19:47
Growth-Promoting Alpha-Globulin and Ageing,rm of dialyzed or undialyzed serum, Although some progress in identifying growth-promoting factors in serum has been made, the function of serum proteins in supporting the growth of cell cultures is not completely understood. In general, the growth-promoting properties of serum have been attributed
作者: 吞下    時間: 2025-3-30 02:13
,Cell Surface Alterations and “in Vitro” Aging of Animal Cells,otype. Conversely, abnormal cells survive indefinately (1). Several biochemical parameters have been studied in the past 10 years though very few of those studied have dealt with cell-surface integrity (2). However it is feasible to conceive that modifications of cell surface components would impair
作者: 強(qiáng)制令    時間: 2025-3-30 04:30
Changes in Lysosomes during Ageing of Parenchymal and Non-Parenchymal Liver Cells,tion and other changes occurring in the liver with age (1) will be reflected in metabolic changes at the cellular level. Since the liver consists of different cell types, a Particular ageing phenomenon observed for the intact organ or measured with a liver homogenate may be an expression of a genera
作者: neologism    時間: 2025-3-30 11:30
The Effect of Age on Mitochondrial Ultrastructure and Enzymes,ll mitochondria were enlarged and rounded with a light “foamy”, vacuolated matrix, short cristae and a loss of dense granules. Quantitative studies showed a 60% increase in the mean size and an increased proportion of larger mitochondria in intact 30 month-old perfused livers. Endothelial and Kupffe
作者: 過渡時期    時間: 2025-3-30 14:40
Creatinephosphokinase in Human Diploid Cell Lines, in various neuromuscular diseases. In some of them, as in Duchenne myopathy, its activity is significantly increased (1). In human tissues, the highest activity was found in muscle, heart and brain. Very low activity was detected in uterus, gall bladder, pylorus, adrenal and thyroid glands (2) and
作者: 難理解    時間: 2025-3-30 19:06

作者: muscle-fibers    時間: 2025-3-30 22:31
Enzymatic Differences between Short-Lived and Long-Lived Drosophila Strains,, among others of the acid phosphatase EC 3.1.3.2. On the other hand the activity of alkaline phosphatase,EC 3.1.3.1. does not change in ageing diploid cells (1), although its activity increased in hydrocortisone-treated diploid cells with prolonged lifespan (2). However, the activity of this enzyme
作者: EVICT    時間: 2025-3-31 03:41
Cell Ageing in the Intestinal Tract,an be tested by comparing cells from the crypts and different levels on the villus in the small intestine. We know from the work of Lesher’s group (1) that the transit time from crypt base to villus tip in the mouse jejunum is just over 50 hr in both 1-year-old and 2 1/2-year-old animals, of which a
作者: 戰(zhàn)勝    時間: 2025-3-31 08:55

作者: 制造    時間: 2025-3-31 10:13
Characteristics of Proliferative Cells from Young, Old, and Transformed WI 38 Cultures, of this non-dividing subpopulation may be monitored by autoradiographic techniques, and these data have predictive value in assessing the amount of potential lifespan completed by a particular cell population during its sojourn in culture.
作者: exacerbate    時間: 2025-3-31 14:13
Cell Ageing in the Intestinal Tract,bout 6 hr is spent in the crypt. There is therefore no difference in the post-mitotic age of cells at a similar level in the villus in adult and aged mice, although they are derived from stem cells of different ages.
作者: BRIEF    時間: 2025-3-31 18:41
Springer Series in Optical Sciences of this non-dividing subpopulation may be monitored by autoradiographic techniques, and these data have predictive value in assessing the amount of potential lifespan completed by a particular cell population during its sojourn in culture.
作者: Reclaim    時間: 2025-3-31 23:39

作者: 反叛者    時間: 2025-4-1 05:36
Book 1975ts studies using different biological systems with results that have been rewarding as information is obtained on patterns of change that are common to more than one experimental system. Indeed, in recent years much more has been learned about the fate of all different types of intermitotic and post
作者: ANNUL    時間: 2025-4-1 08:51

作者: 杠桿支點(diǎn)    時間: 2025-4-1 10:45
G. Bosco,A. Carena,V. Curri,P. Poggiolinihose studied have dealt with cell-surface integrity (2). However it is feasible to conceive that modifications of cell surface components would impair cell division since such events have been described for cell differentiation, cell transformation and even for the different phases of the cell cycle (3–5).




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