作者: 小蟲(chóng) 時(shí)間: 2025-3-21 21:41 作者: 不怕任性 時(shí)間: 2025-3-22 03:49 作者: 不能平靜 時(shí)間: 2025-3-22 07:34 作者: 駁船 時(shí)間: 2025-3-22 08:50
,NF-κB Spiky Oscillations,inflammation, stress responses, and apoptosis. NF-κB is activated by many external stimuli, including bacteria, viruses, and various stresses and proteins, after which it initiates proper cell responses by regulating expression of various genes. The NF-κB signaling system is conserved to operate in 作者: NAIVE 時(shí)間: 2025-3-22 13:57
Tick, Tock, Circadian Clocks,ke cycle, body temperature, blood pressure and hormone secretion [1]. The disruption of circadian rhythms increases the risk of getting various chronic diseases such as cancer, diabetes, mood disorders and sleep disorders [2]. The key oscillatory mechanism of the circadian clock is a transcriptional作者: NAIVE 時(shí)間: 2025-3-22 19:19 作者: Pamphlet 時(shí)間: 2025-3-23 00:27
Modeling cAMP Oscillations in Budding Yeast,ce in the environment in order to modulate their metabolism, which is in turn vital to maintain an optimal growth rate. The cAMP/PKA signal transduction pathway performs this task: the pathway ‘senses’ environmental glucose and carries out a variety of biological roles, including activation of growt作者: 甜食 時(shí)間: 2025-3-23 03:18 作者: 他去就結(jié)束 時(shí)間: 2025-3-23 05:58
The , Operon,the digestion of available nutrients. The . system produces a switch-like dynamic behavior, where the switching between ‘on’ and ‘off’ states of . gene transcription depends on the specific thresholds of nutrient concentrations. As . operon regulation has been extensively studied and is one of the m作者: Working-Memory 時(shí)間: 2025-3-23 13:47
Fate Decisions of CD4+ T Cells,tion and activation of several types of memoryenabling immune cells, including T cells and B cells. A group of T cells with surface marker CD4 coordinate immune responses by activating and modulating other immune cells. Specific immune responses mounted by CD4. T cells depend on the subtypes of thes作者: FLORA 時(shí)間: 2025-3-23 15:34 作者: maverick 時(shí)間: 2025-3-23 21:41
Collective Molecular Motor Transport,nto proteins. Some of these proteins must then be imported back into the nucleus. Others are packaged into membrane vesicles, which in turn must be trafficked to the plasma membrane and exocytosed from the cell. The list of such examples has hundreds of entries [1]. An energetically ‘cheap’ way to t作者: BILL 時(shí)間: 2025-3-23 23:14 作者: 地名詞典 時(shí)間: 2025-3-24 02:45 作者: 控訴 時(shí)間: 2025-3-24 10:23 作者: BUOY 時(shí)間: 2025-3-24 13:42
Identifying Virus-Like Regions in Microbial Genomes Using Hidden Markov Models, have been studied for over a century due to their medical or agricultural importance, there is growing appreciation for the large diversity of viruses that inhabit the biosphere and infect microorganisms such as bacteria, archaea, single-celled eukaryotes, and even other viruses [2–5]. All of these作者: 領(lǐng)巾 時(shí)間: 2025-3-24 15:06 作者: ALT 時(shí)間: 2025-3-24 19:41
nt project.Features contributions from key scientists in the.This book provides case studies that can be used in Systems Biology related classes. Each case study has the same structure which answers the following questions: What is the biological problem and why is it interesting? What are the relev作者: 清楚說(shuō)話 時(shí)間: 2025-3-25 00:38
Glycolytic Oscillations,y in living cells. Therefore, glycolysis allows a?living cell to use glucose as its main energy source. Interestingly, energy production in glycolysis is not always a steady process, but, under certain conditions, it can exhibit oscillatory dynamics.作者: Arroyo 時(shí)間: 2025-3-25 03:38 作者: 危險(xiǎn) 時(shí)間: 2025-3-25 09:13
Virus Dynamics,d to quantify virus and host characteristics that capture the kinetics apparent in empirical viral data, and explain how empirical data can be used to select among models with various levels of biological complexity. 作者: Leisureliness 時(shí)間: 2025-3-25 13:01 作者: 違反 時(shí)間: 2025-3-25 19:29
Textbook 2021o they compare to the known facts of the cell physiology? Does the model make predictions? What can be done to extend the model? The book presents a summary of results and references to more relevant sources..The volume contains the classic collection of topics and studies that are well established yet novel in the systems biology field.?.作者: 幻影 時(shí)間: 2025-3-25 20:28 作者: 欺騙手段 時(shí)間: 2025-3-26 00:37 作者: conscribe 時(shí)間: 2025-3-26 07:16 作者: chalice 時(shí)間: 2025-3-26 12:06
,NF-κB Spiky Oscillations,emporal encoding of signals. Mathematical models that were successful in explaining the dynamic behavior of NF-κB are now used to demonstrate the power of mathematical modeling approaches in Biological Sciences.作者: omnibus 時(shí)間: 2025-3-26 15:07
Ulrike Lechner,Christian Lengauery in living cells. Therefore, glycolysis allows a?living cell to use glucose as its main energy source. Interestingly, energy production in glycolysis is not always a steady process, but, under certain conditions, it can exhibit oscillatory dynamics.作者: Arb853 時(shí)間: 2025-3-26 18:10 作者: Euthyroid 時(shí)間: 2025-3-26 23:34 作者: ectropion 時(shí)間: 2025-3-27 03:30 作者: exorbitant 時(shí)間: 2025-3-27 08:53 作者: 刺穿 時(shí)間: 2025-3-27 11:01 作者: Spinal-Fusion 時(shí)間: 2025-3-27 15:03
https://doi.org/10.1007/978-3-030-67742-8Dynamic modeling; Biological Networks; Bio-systems; Genetic Networks; Synthetic biology; Signaling Pathwa作者: 假設(shè) 時(shí)間: 2025-3-27 17:45 作者: 協(xié)奏曲 時(shí)間: 2025-3-28 00:50 作者: 切掉 時(shí)間: 2025-3-28 05:59 作者: 粗鄙的人 時(shí)間: 2025-3-28 09:39 作者: MIR 時(shí)間: 2025-3-28 13:00 作者: Tdd526 時(shí)間: 2025-3-28 17:10
Wolfgang Ecker,Viktor Preis,Claus Schneiderstem’), and that solutions of these equations can be identified with laboratory observations and can predict the outcome of novel experiments. We called this approach the ‘dynamical perspective on molecular cell biology.’ In this case study we elaborate on this notion by showing that the behavior of作者: 逗留 時(shí)間: 2025-3-28 20:31 作者: superfluous 時(shí)間: 2025-3-29 02:21 作者: 恩惠 時(shí)間: 2025-3-29 05:32
Optimization of Stochastic Modelske cycle, body temperature, blood pressure and hormone secretion [1]. The disruption of circadian rhythms increases the risk of getting various chronic diseases such as cancer, diabetes, mood disorders and sleep disorders [2]. The key oscillatory mechanism of the circadian clock is a transcriptional作者: 先驅(qū) 時(shí)間: 2025-3-29 08:33 作者: Isolate 時(shí)間: 2025-3-29 11:54
https://doi.org/10.1007/978-1-4613-1599-5ce in the environment in order to modulate their metabolism, which is in turn vital to maintain an optimal growth rate. The cAMP/PKA signal transduction pathway performs this task: the pathway ‘senses’ environmental glucose and carries out a variety of biological roles, including activation of growt作者: Respond 時(shí)間: 2025-3-29 16:39 作者: Needlework 時(shí)間: 2025-3-29 22:42
https://doi.org/10.1007/978-1-4613-1599-5the digestion of available nutrients. The . system produces a switch-like dynamic behavior, where the switching between ‘on’ and ‘off’ states of . gene transcription depends on the specific thresholds of nutrient concentrations. As . operon regulation has been extensively studied and is one of the m作者: 無(wú)價(jià)值 時(shí)間: 2025-3-30 01:43
Michael S. McGrath,Valerie L. Ngtion and activation of several types of memoryenabling immune cells, including T cells and B cells. A group of T cells with surface marker CD4 coordinate immune responses by activating and modulating other immune cells. Specific immune responses mounted by CD4. T cells depend on the subtypes of thes作者: 傾聽(tīng) 時(shí)間: 2025-3-30 05:52
Alexander D. Romaschin,Donald A. G. Mickle, especially biochemical reactions, to occur at random times. Such noise is not manifest if the molecules participating?in a process?are abundant, e.g., decay of an abundant molecule in a cell, or a reaction measured in a whole tissue (large total number of molecules in?many cells). This is because 作者: 值得尊敬 時(shí)間: 2025-3-30 12:05 作者: osculate 時(shí)間: 2025-3-30 12:40 作者: 疏忽 時(shí)間: 2025-3-30 16:35
Dielectric Breakdown in Solids,elop novel drugs or novel combinations of available drugs, quantitative Systems Pharmacological (QSP) models were built to help us understanding the complex pharmacokinetic (PK) and pharmacodynamic (PD) of multiple treatment regimens. In this chapter, we illustrated how to construct and independentl作者: infringe 時(shí)間: 2025-3-30 23:50
Diffuse Discharge Opening Switches,fected individual and the potential role of various immune interventions. In this chapter, we describe the general principles of modeling within-host virus dynamics, discuss the usefulness of such models in predicting disease establishment inside an infected individual, explain how models can be use作者: 組裝 時(shí)間: 2025-3-31 03:40
J. S. Lazo,J. E. Mignano,S. M. Sebti have been studied for over a century due to their medical or agricultural importance, there is growing appreciation for the large diversity of viruses that inhabit the biosphere and infect microorganisms such as bacteria, archaea, single-celled eukaryotes, and even other viruses [2–5]. All of these作者: GROUP 時(shí)間: 2025-3-31 06:47 作者: 啪心兒跳動(dòng) 時(shí)間: 2025-3-31 10:54
Computational Software,tave is a free alternative to MATLAB), and Python. Also freely available is Capasi [2] and VCell [3] computational tools, and BioNetGen [4] and Kappa [5] for rule-based modeling. These?tools are frequently used by the Systems Biology community.作者: 好開(kāi)玩笑 時(shí)間: 2025-3-31 16:19
What can be done to extend the model? The book presents a summary of results and references to more relevant sources..The volume contains the classic collection of topics and studies that are well established yet novel in the systems biology field.?.978-3-030-67744-2978-3-030-67742-8作者: 克制 時(shí)間: 2025-3-31 19:44 作者: 令人不快 時(shí)間: 2025-3-31 22:41
Wolfgang Ecker,Viktor Preis,Claus Schneider, a parameter in the model). A summary of the generic bifurcations of dynamical systems is, in this context, a catalog of the basic types of signal-response curves that can be exhibited by living cells. We apply this idea to a model of cell cycle regulation in fission yeast.作者: excrete 時(shí)間: 2025-4-1 03:48
