作者: incredulity 時(shí)間: 2025-3-21 22:27
978-3-642-07291-8Springer-Verlag Berlin Heidelberg 2004作者: critique 時(shí)間: 2025-3-22 04:10
An Age of Transition: Lagrange and Legendre,ributed for many years) to drug discovery and development and, more broadly, to the practice of health care. Particular emphasis will be placed on examining the role of genetics, that is, acquired or inherited variations at the level of DNA-encoded information, with regard to common complex diseases作者: beta-cells 時(shí)間: 2025-3-22 08:18 作者: affinity 時(shí)間: 2025-3-22 12:43 作者: 會(huì)犯錯(cuò)誤 時(shí)間: 2025-3-22 14:56
Positive Finiteness of Number Systems,s developed countries. Atherosclerosis is a complex disease with both environmental and genetic determinants. Genetic susceptibility is governed by an unfavorable combination of variants in genes involving multiple pathways, each with small quantitative effects on gene function. However, our underst作者: 會(huì)犯錯(cuò)誤 時(shí)間: 2025-3-22 17:15 作者: Visual-Field 時(shí)間: 2025-3-22 22:35
Explicit Congruences for Euler Polynomials,bution in the general population with no natural hypertensive threshold. Decisions regarding who to treat and with what drugs are based upon morbidity and mortality data in large population studies, the presence/absence of co-existing disease and cost. Because of variation between individuals in the作者: 新星 時(shí)間: 2025-3-23 02:57 作者: Intractable 時(shí)間: 2025-3-23 09:18 作者: 和平主義者 時(shí)間: 2025-3-23 10:19
Morphic Heights and Periodic Points,ent, these risk factor predictions are imperfect and the reaction has been generally termed unpredictable (or idiosyncratic). As a result, we and others have suggested that a variable genetic context may contribute to risk of proarrhythmia on exposure to specific drugs. This research is most advance作者: 謊言 時(shí)間: 2025-3-23 15:53
M. Einsiedler,G. Everest,T. Ward classically defined as an impaired ability of insulin to mediate its metabolic actions such as increasing glucose uptake into skeletal muscle, suppressing hepatic glucose production and suppressing lipolysis. However, the scope of insulin action is not restricted to the maintenance of glucose homeo作者: osteocytes 時(shí)間: 2025-3-23 18:25
Applications of Linear Forms in Logarithmsde variety of cardiovascular diseases, including atherosclerosis, hypertension, congestive heart failure, thrombosis, stroke, and diabetes mellitus. This chapter will review the roles that NO synthases play in normal vascular function and in the molecular mechanisms of disease processes, focusing on作者: 密碼 時(shí)間: 2025-3-23 23:26 作者: HEDGE 時(shí)間: 2025-3-24 02:40 作者: Salivary-Gland 時(shí)間: 2025-3-24 10:34
Rational Points on Higher-Genus Curvesof the functional integrity of tissues. These remodelling processes are tightly controlled to maintain a fine balance between the extracellular matrix-degrading enzymes and their inhibitors and thus regulate tissue function and development. Matrix degradation is mediated by a variety of proteases, b作者: CHAFE 時(shí)間: 2025-3-24 12:59
Applications of Linear Forms in Logarithmsr a significant proportion of all hospital admissions and putting enormous financial strain on health delivery systems. Recent developments in the understanding of the molecular mechanisms of myocardial disease have led to the identification of novel therapeutic targets, and the availability of effi作者: INERT 時(shí)間: 2025-3-24 18:46 作者: hardheaded 時(shí)間: 2025-3-24 22:53
Martin R. Wilkins (Professor)Includes supplementary material: 作者: 個(gè)阿姨勾引你 時(shí)間: 2025-3-25 02:21
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/c/image/221972.jpg作者: CAMEO 時(shí)間: 2025-3-25 03:32 作者: 單片眼鏡 時(shí)間: 2025-3-25 08:23
0171-2004 structure of human DNA would lead to new and better medicines. These medicines would be better because they would be tailored to individual patients, maximising the chances of a therapeutic response and mi- nimising the risks of an adverse event. Taking the idea further, pundits have pre- dicted th作者: 猛然一拉 時(shí)間: 2025-3-25 12:15 作者: 強(qiáng)行引入 時(shí)間: 2025-3-25 16:02 作者: 放肆的你 時(shí)間: 2025-3-25 22:16
Positive Finiteness of Number Systems,th stratify patients according to risk and to develop targeted therapeutics based on an individual genotype and (2) identify new genes/pathways that contribute to atherosclerosis that may be new targets for drug action.作者: IRS 時(shí)間: 2025-3-26 00:32
Applications of Linear Forms in LogarithmsNO synthase function or expression levels. The cellular pathways that involve NO are complex and offer not only insights into how abnormalities in NO signaling can lead to disease but also opportunities and targets on which to intervene to prevent or treat disease.作者: Innovative 時(shí)間: 2025-3-26 06:10
Genes That Modify Susceptibility to Atherosclerosis: Targets for Drug Action,th stratify patients according to risk and to develop targeted therapeutics based on an individual genotype and (2) identify new genes/pathways that contribute to atherosclerosis that may be new targets for drug action.作者: CLEAR 時(shí)間: 2025-3-26 10:55 作者: 評(píng)論性 時(shí)間: 2025-3-26 15:56 作者: 裁決 時(shí)間: 2025-3-26 16:58 作者: Anticoagulants 時(shí)間: 2025-3-26 20:57 作者: 職業(yè)拳擊手 時(shí)間: 2025-3-27 04:10 作者: 細(xì)查 時(shí)間: 2025-3-27 08:26 作者: Engulf 時(shí)間: 2025-3-27 12:25
The Genetic Basis of Essential Hypertension and Its Implications for Treatment,bution in the general population with no natural hypertensive threshold. Decisions regarding who to treat and with what drugs are based upon morbidity and mortality data in large population studies, the presence/absence of co-existing disease and cost. Because of variation between individuals in the作者: monochromatic 時(shí)間: 2025-3-27 15:56
Genetic Predisposition to Cardiac Hypertrophy,de and nature of the response is influenced by both genetic and nongenetic factors. Mutations in single genes underlie hypertrophic cardiomyopathy (HCM) but there is remarkable variability in the phenotypic expression of HCM. Both the genetic background, referred to as the modifier genes, and probab作者: FIS 時(shí)間: 2025-3-27 19:12 作者: cutlery 時(shí)間: 2025-3-28 01:04 作者: 鋸齒狀 時(shí)間: 2025-3-28 03:17 作者: maculated 時(shí)間: 2025-3-28 09:02 作者: 全面 時(shí)間: 2025-3-28 11:29
Association of Thrombotic Disease with Genetic Polymorphism of Haemostatic Genes: Relevance to Pharr protein expression levels or encoding protein structure alteration affecting function have mechanistically clear effects on thrombin generation or fibrinolysis, which correlate with increased risk of VT. About half the incidence of VT can be attributed to these genetic variants. The risk of VT con作者: 蚊帳 時(shí)間: 2025-3-28 17:56
The Influence of Genetic Factors on Leukocyte and Endothelial Cell Adhesion Molecules,uclear cells into the blood vessel wall, which is orchestrated by adhesion molecules expressed both on leukocytes and on endothelium. Over the last few years, these molecules have been extensively studied, leading to a well-described paradigm of leukocyte recruitment, termed the adhesion cascade. Ad作者: 加花粗鄙人 時(shí)間: 2025-3-28 22:22 作者: APO 時(shí)間: 2025-3-28 23:13
Current Perspectives on Gene and Cell-Based Therapies for Myocardial Protection, Rescue and Repair,r a significant proportion of all hospital admissions and putting enormous financial strain on health delivery systems. Recent developments in the understanding of the molecular mechanisms of myocardial disease have led to the identification of novel therapeutic targets, and the availability of effi作者: 分期付款 時(shí)間: 2025-3-29 05:04
Book 2004rom excessive hypotension. This observation was made over 20 years ago and predated designs to sequence the human genome. Nonetheless, it raised aware- ness of variation in drug metabolism and was correctly assigned to genetic poly- morphisms affecting CYP2D6. Together with the discovery of pseudoch作者: 下垂 時(shí)間: 2025-3-29 08:00 作者: 圓桶 時(shí)間: 2025-3-29 12:27 作者: 集合 時(shí)間: 2025-3-29 16:10 作者: resilience 時(shí)間: 2025-3-29 21:08 作者: Fulsome 時(shí)間: 2025-3-30 03:53 作者: 羊欄 時(shí)間: 2025-3-30 05:26 作者: expeditious 時(shí)間: 2025-3-30 09:23 作者: GRAIN 時(shí)間: 2025-3-30 14:32 作者: Cerebrovascular 時(shí)間: 2025-3-30 17:04 作者: 戲法 時(shí)間: 2025-3-30 23:39 作者: 無法治愈 時(shí)間: 2025-3-31 00:54
Rational Points on Higher-Genus Curveslerosis, aneurysms, arthritis and cancer. These are complex traits where the disease is influenced by a combination of common variation in a constellation of genes and the effect of a wide range of environmental variables. Thus, the mechanisms underlying the development of the disease will be modula
