標題: Titlebook: Cardiac Glycosides; Part I: Experimental Kurt Greeff (Direktor) Book 1981 Springer-Verlag Berlin Heidelberg 1981 Drogen.Hormone.Lipid.Respi [打印本頁] 作者: 老鼠系領帶 時間: 2025-3-21 16:37
書目名稱Cardiac Glycosides影響因子(影響力)
書目名稱Cardiac Glycosides影響因子(影響力)學科排名
書目名稱Cardiac Glycosides網(wǎng)絡公開度
書目名稱Cardiac Glycosides網(wǎng)絡公開度學科排名
書目名稱Cardiac Glycosides被引頻次
書目名稱Cardiac Glycosides被引頻次學科排名
書目名稱Cardiac Glycosides年度引用
書目名稱Cardiac Glycosides年度引用學科排名
書目名稱Cardiac Glycosides讀者反饋
書目名稱Cardiac Glycosides讀者反饋學科排名
作者: sterilization 時間: 2025-3-21 23:06
Chemistry and Structure-Activity Relationships of Cardioactive Steroidsamined repeatedly. The reason for this sustained interest has its roots in the medical use of CAS with the ever-increasing number of the elderly, the narrow therapeutic spectrum, and the wide differences in patient responses to this class of compounds (see this Handbook, Vol. 56/II, Chap. 12). It is作者: locus-ceruleus 時間: 2025-3-22 01:31 作者: 繁忙 時間: 2025-3-22 07:42
Use of Radioactively Labeled Glycosidesique. As in the case of other drugs, radioisotope labeled cardiac glycosides offer valuable analytical advantages in the study of absorption, distribution, metabolic breakdown, and elimination. They can be used to measure glycoside concentrations in all forms of biological material. The technique is作者: obstruct 時間: 2025-3-22 10:45
ATPase for the Determination of Cardiac Glycosidesterwards he also found that cardiac glycosides are able to inhibit ATPase activity by binding to the enzyme (., 1960). Extensive work was done by different groups to purify and characterize this enzyme which is specifically associated with active cation transport. Recently the molecular weight of th作者: 陶瓷 時間: 2025-3-22 16:15
Rubidium Uptake in Erythrocytesd to be inhibited by the cardiac glycosides (c.g.), k-strophanthoside, and digitoxin and their aglucons (., 1953). The drug concentrations necessary to yield this effect ranged from 0.1 μg/ml to 10μg/ml. This effect was shown to be due to an inhibition of membrane Na.-K.-ATPase activity (. et al., 1作者: 陶瓷 時間: 2025-3-22 20:21
Evaluation of Cardiac Glycosides in the Intact Animaltain guidelines for their therapeutic dosage. Subsequently, as knowledge of the drugs advanced, animal experiments served chiefly to demonstrate and elucidate the actions of the glycosides. More recently, experimental animals have been employed mainly to determine the therapeutic range, intestinal a作者: habile 時間: 2025-3-23 00:14
The Use of the Isolated Papillary Muscle for the Evaluation of Positive Inotropic Effects of Cardioaion curve is, at present, the most suitable method (for review see ., 1972). Although isometric contraction curves can, in principle, be obtained from a complete isolated heart contracting against an intraventricular balloon (Fig. 1 b of Chap. 11) as demonstrated by . and . (1910), the use of papill作者: Reverie 時間: 2025-3-23 04:47 作者: DEAWL 時間: 2025-3-23 08:45 作者: 過度 時間: 2025-3-23 10:16
Influence of Cardiac Glycosides on Electrophysiologic Processesy act. With the introduction of new approaches to investigation, such as the voltage clamp technique or ion-selective microelectrodes, considerable progress has been made over the last decade. It is the purpose of this chapter to review the advances made in this field. The scope of this article has 作者: innovation 時間: 2025-3-23 14:41
Influence of Cardiac Glycosides on Myocardial Energy Metabolismwell known clinically that the therapeutic efficiency of these drugs is to a certain degree dependent on the metabolic state of the heart; they are most effective in hearts with no defects in energy metabolism such as congestive heart failure due to excessive hemodynamic pressure loads (e.g., hypert作者: 完成 時間: 2025-3-23 21:34
Effects of Cardiac Glycosides on Na+, K+-ATPase53; see . and ., 1959). Thus, with the discovery of Na ., K.-ATPase (., 1957; . and ., 1957), the effect of these glycosides on the enzyme activity was examined and a specific inhibition was observed (. et al., 1960; ., 1960; see Fig. 1). The interaction of cardiac glycosides with the enzyme, and it作者: Desert 時間: 2025-3-24 00:06
Influence of Cardiac Glycosides on their Receptorer, generally accepted that their effects are directly on the cardiac cell (for reviews see . and ., 1971; . and ., 1979). A great variety of cellular and subcellular systems has been studied as putative primary points of interaction such as: polymerization of cardiac actin (. et al., 1949), myosin 作者: 有說服力 時間: 2025-3-24 04:14
Stimulation and Inhibition of the Na+, K+-Pump by Cardiac Glycosideshe mechanism of this inhibition which paralleled the study of the properties of Na., K.-ATPase (initially described by ., 1957) has allowed us to describe the biochemical mechanism of the Na., K.-pump. Furthermore, the presence of a Na., K.-pump in most of the cells and the multiple functions contro作者: 言外之意 時間: 2025-3-24 09:01
https://doi.org/10.1007/978-3-658-29782-4and narrow therapeutic range of these compounds. Today, however, digitalis glycosides are indispensable, as there are no other substances known which can increase the contractility of the heart, without increasing but lowering beat frequency, a characteristic of cardiac glycosides which ensures an i作者: 過時 時間: 2025-3-24 13:52 作者: prodrome 時間: 2025-3-24 16:45 作者: 整潔 時間: 2025-3-24 22:25 作者: 閃光你我 時間: 2025-3-24 23:31 作者: 露天歷史劇 時間: 2025-3-25 03:34
Optimality Conditions for Convex Problems,d to be inhibited by the cardiac glycosides (c.g.), k-strophanthoside, and digitoxin and their aglucons (., 1953). The drug concentrations necessary to yield this effect ranged from 0.1 μg/ml to 10μg/ml. This effect was shown to be due to an inhibition of membrane Na.-K.-ATPase activity (. et al., 1作者: Nibble 時間: 2025-3-25 11:24 作者: 座右銘 時間: 2025-3-25 14:50 作者: NEEDY 時間: 2025-3-25 19:47 作者: scoliosis 時間: 2025-3-25 20:33 作者: 凈禮 時間: 2025-3-26 02:50 作者: Virtues 時間: 2025-3-26 04:32
The Subdifferential of Convex Functionals,well known clinically that the therapeutic efficiency of these drugs is to a certain degree dependent on the metabolic state of the heart; they are most effective in hearts with no defects in energy metabolism such as congestive heart failure due to excessive hemodynamic pressure loads (e.g., hypert作者: aesthetic 時間: 2025-3-26 10:19
A Short Course in Control Theory,53; see . and ., 1959). Thus, with the discovery of Na ., K.-ATPase (., 1957; . and ., 1957), the effect of these glycosides on the enzyme activity was examined and a specific inhibition was observed (. et al., 1960; ., 1960; see Fig. 1). The interaction of cardiac glycosides with the enzyme, and it作者: 吞吞吐吐 時間: 2025-3-26 15:30
Generalized Gradients in Banach Space,er, generally accepted that their effects are directly on the cardiac cell (for reviews see . and ., 1971; . and ., 1979). A great variety of cellular and subcellular systems has been studied as putative primary points of interaction such as: polymerization of cardiac actin (. et al., 1949), myosin 作者: 是他笨 時間: 2025-3-26 17:09 作者: 斥責 時間: 2025-3-26 23:32 作者: 勛章 時間: 2025-3-27 03:20
Rubidium Uptake in Erythrocytesd to be inhibited by the cardiac glycosides (c.g.), k-strophanthoside, and digitoxin and their aglucons (., 1953). The drug concentrations necessary to yield this effect ranged from 0.1 μg/ml to 10μg/ml. This effect was shown to be due to an inhibition of membrane Na.-K.-ATPase activity (. et al., 1960; . and ., 1961; ., 1957).作者: curettage 時間: 2025-3-27 07:28 作者: 亞當心理陰影 時間: 2025-3-27 12:40
Radioimmunologic MethodsBased on the work of . and . (1959) on the detection of insulin, radioimmunoassay (RIA) has now developed to be the best and most versatile method for the detection of trace amounts of biologically active substances (hereinafter termed antigens). To enable the detection of an antigen using RIA, the following conditions must be fulfilled作者: abject 時間: 2025-3-27 13:36 作者: 傷心 時間: 2025-3-27 18:52
https://doi.org/10.1007/978-3-658-29782-4and narrow therapeutic range of these compounds. Today, however, digitalis glycosides are indispensable, as there are no other substances known which can increase the contractility of the heart, without increasing but lowering beat frequency, a characteristic of cardiac glycosides which ensures an increase in cardiac efficiency.作者: 不給啤 時間: 2025-3-28 00:47 作者: 保全 時間: 2025-3-28 05:14
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/c/image/221780.jpg作者: mastoid-bone 時間: 2025-3-28 06:30 作者: critique 時間: 2025-3-28 13:14
978-3-642-68165-3Springer-Verlag Berlin Heidelberg 1981作者: Organization 時間: 2025-3-28 17:00 作者: byline 時間: 2025-3-28 20:30
The Positive Inotropic Action of Cardiac Glycosides on Cardiac Ventricular Muscle the left ventricle of the isolated cat heart. Their tracing (Fig. 1 b) shows that, because of the greater speed of the force development under the effect of the glycoside, the height of the contraction curve, representing the peak force of the isometric contraction, was increased.作者: inhibit 時間: 2025-3-29 02:48
Book 1981d topical issues discussed from varying viewpoints. This re- minds the reader that scientific horizons in medicine should often be widened or revised. I would like to thank DR. ALANNA Fox and DR. K. ANANTHARAMAN for their help and advice in the revision of certain chapters. I am also grateful to Spr作者: Monolithic 時間: 2025-3-29 05:54
0171-2004 r revised. I would like to thank DR. ALANNA Fox and DR. K. ANANTHARAMAN for their help and advice in the revision of certain chapters. I am also grateful to Spr978-3-642-68165-3978-3-642-68163-9Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: gruelling 時間: 2025-3-29 10:59 作者: PHONE 時間: 2025-3-29 15:22 作者: 軌道 時間: 2025-3-29 19:01 作者: Constitution 時間: 2025-3-29 21:45
Optimality Conditions for Convex Problems,bsorption, and duration of action of new glycosides or semisynthetic derivatives. In addition, numerous investigations have been carried out to study interactions with other drugs which potentiate or attentuate their effects or which alter their therapeutic range.作者: 廚房里面 時間: 2025-3-30 03:31
The Subdifferential of Convex Functionals,ls of different methods are described by . (1935), . (1936), . (1966), . and . (1967), . (1968), and . (1971). In addition to the particular methods, some experimental results have also been included to provide some idea of the usefulness of the procedures and to indicate several possible modifications.作者: geriatrician 時間: 2025-3-30 06:59
The Subdifferential of Convex Functionals,had to be confined to certain aspects of the overall problem. Emphasis will be placed on the mechanical and electrical actions that cardiac glycosides exert on isolated but otherwise “normal” ventricular tissue. The reader is also referred to other review articles (., 1977; ., 1977; ., 1977a; . et al., 1978 a, b).作者: explicit 時間: 2025-3-30 08:52
A Short Course in Control Theory,s possible relationship to the pharmacologic or toxic actions of these agents have been extensively studied during the last two decades (see the following review articles: ., 1964; ., 1964, 1965; ., 1965; ., 1971, 1972a; . and ., 1971; . and ., 1973; . et al., 1975; . and ., 1976, 1977; ., 1977; . and ., 1977; ., 1977; ., 1977; . et al., 1977).作者: sulcus 時間: 2025-3-30 14:08 作者: 腫塊 時間: 2025-3-30 18:47 作者: 禁令 時間: 2025-3-30 21:38 作者: 是突襲 時間: 2025-3-31 04:05
Influence of Cardiac Glycosides on Myocardial Energy Metabolismd severe thiamine deficiency (beriberi) in which energy supply is impaired (. and ., 1975) and experimentally it has been shown that heart failure caused by poisons that reduce energy-rich phosphate pools (cyanide, dinitrophenol, etc.) is not relieved by digitalis (. and ., 1955).作者: Adrenaline 時間: 2025-3-31 06:39 作者: Ovulation 時間: 2025-3-31 12:24 作者: 2否定 時間: 2025-3-31 13:24
Evaluation of Cardiac Glycosides in the Intact Animalbsorption, and duration of action of new glycosides or semisynthetic derivatives. In addition, numerous investigations have been carried out to study interactions with other drugs which potentiate or attentuate their effects or which alter their therapeutic range.
