標題: Titlebook: Cardiac Glycoside Receptors and Positive Inotropy; Evidence for more th E. Erdmann Conference proceedings 1984 Dr. Dietrich Steinkopff Verl [打印本頁] 作者: Enclosure 時間: 2025-3-21 19:26
書目名稱Cardiac Glycoside Receptors and Positive Inotropy影響因子(影響力)
書目名稱Cardiac Glycoside Receptors and Positive Inotropy影響因子(影響力)學科排名
書目名稱Cardiac Glycoside Receptors and Positive Inotropy網絡公開度
書目名稱Cardiac Glycoside Receptors and Positive Inotropy網絡公開度學科排名
書目名稱Cardiac Glycoside Receptors and Positive Inotropy被引頻次
書目名稱Cardiac Glycoside Receptors and Positive Inotropy被引頻次學科排名
書目名稱Cardiac Glycoside Receptors and Positive Inotropy年度引用
書目名稱Cardiac Glycoside Receptors and Positive Inotropy年度引用學科排名
書目名稱Cardiac Glycoside Receptors and Positive Inotropy讀者反饋
書目名稱Cardiac Glycoside Receptors and Positive Inotropy讀者反饋學科排名
作者: 文藝 時間: 2025-3-21 23:58
,Theory of ligand — receptor interactions — Evidence for more than one site, data presentation affects the data inhomogeneously with respect to the experimental error. Thus a non-linear fitting procedure should be preferred for data analysis. Furthermore this approach allows for reliable weighting of the measurements according to the experimental error.作者: genuine 時間: 2025-3-22 01:36
Cardiac Glycosides and sodium/potassium-ATPase,e and their receptor. Inhibition of this enzyme by cardiac glycosides leads for instance in the heart to a decrease or a delay in membrane sodium/potassium- ion transport, and indirectly to an increase in the intracellular ionized calcium-concentration and an increase in cardiac contractile force. A作者: 草率男 時間: 2025-3-22 06:44 作者: 傻 時間: 2025-3-22 12:19 作者: Gum-Disease 時間: 2025-3-22 13:20
Binding sites for ouabain in human and rat erythrocytes and in rat heart cells,een these two binding sites are summarized for intact cells and for their membranes. Our biochemical data do not suggest a physiological role for each class of sites..The membrane sites were modified by varying (a) the content of cholesterol or (b) the distribution of fatty acids leading to changes 作者: Gum-Disease 時間: 2025-3-22 20:38 作者: choroid 時間: 2025-3-22 23:20 作者: 可用 時間: 2025-3-23 02:43 作者: 反抗者 時間: 2025-3-23 06:25 作者: addition 時間: 2025-3-23 13:16 作者: Digest 時間: 2025-3-23 17:41
Positive inotropic effects of digitoxin- and digoxin-glucuronide in human isolated ventricular hear) and digoxin (dg-gluc). The parent compounds digitoxin (dt) and digoxin (dg) were studied for comparison and all compounds were also investigated in guinea-pig isolated papillary muscles. All compounds increased myocardial force of contraction in human preparations in a concentration-dependent mann作者: 陶器 時間: 2025-3-23 19:06 作者: Insul島 時間: 2025-3-23 22:58
Overview: 978-3-642-72378-0978-3-642-72376-6作者: ENACT 時間: 2025-3-24 03:15 作者: Ptsd429 時間: 2025-3-24 07:58 作者: macabre 時間: 2025-3-24 12:43 作者: tendinitis 時間: 2025-3-24 18:39 作者: 蟄伏 時間: 2025-3-24 21:29
Ursachen und Folgen von Staatsversagengnificance of these different types of binding sites, specific 3H-ouabain binding, force of contraction and .Rb.-uptake were measured simultaneously in contracting cat papillary muscles and in guinea pig atria..The results in the digitalis sensitive cat shows one type of cardiac glycoside receptors 作者: Proclaim 時間: 2025-3-25 01:20
https://doi.org/10.1007/978-3-663-08792-2 positive inotropic effect, even if their action on preload and afterload has to be taken into account (12). Despite of the large interest devoted to these drugs, the mechanism of their inotropic action is still a matter of controversy. In 1953, Schatzman reported that cardiac glycosides inhibit the作者: Impugn 時間: 2025-3-25 06:56 作者: 增長 時間: 2025-3-25 10:49 作者: 贊成你 時間: 2025-3-25 14:49 作者: Condense 時間: 2025-3-25 18:17 作者: monologue 時間: 2025-3-25 21:15
Nonradioactive Analysis of Biomolecules obtained at a K. = 2.6 x 10. mol/1 (about 40% of the binding sites) whereas a low affinity, high capacity binding was established at a KD = 1.3 x 10. mol/1 (about 60% of the binding sites). Similar results were obtained when studying the effect of increasing Na.-concentrations on ouabain binding: a作者: Chromatic 時間: 2025-3-26 02:52 作者: 戲法 時間: 2025-3-26 04:38
https://doi.org/10.1007/978-3-662-00144-8) and digoxin (dg-gluc). The parent compounds digitoxin (dt) and digoxin (dg) were studied for comparison and all compounds were also investigated in guinea-pig isolated papillary muscles. All compounds increased myocardial force of contraction in human preparations in a concentration-dependent mann作者: 序曲 時間: 2025-3-26 09:40 作者: ENNUI 時間: 2025-3-26 16:09
https://doi.org/10.1007/978-3-642-72376-6Stent; arrhythmia; cardiology; cardiovascular; circulation; drugs; heart; heart failure; pharmacodynamics; re作者: 健忘癥 時間: 2025-3-26 16:57
978-3-642-72378-0Dr. Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt — Production: Holger Frey 1984作者: 不出名 時間: 2025-3-27 00:47 作者: RLS898 時間: 2025-3-27 02:24
Zukunftsf?hige Strukturen schaffenCardiac glycoside receptors were defined by simultaneous measurement of .H-ouabain binding and its effects on cardiac cell membranes, contracting cardiac muscle and cultured cardiac cells. These measurements show that:作者: maintenance 時間: 2025-3-27 08:30
Cardiac glycoside binding sites in cultured heart muscle cells,Binding of (.H)-ouabain to cultured cardiac muscle and non muscle cells from chicken embryos and neonatal rats has been characterized and correlated with ouabain-induced inhibition of the sodium pump, as well as with the positive inotropic action of the drug.作者: Armory 時間: 2025-3-27 11:23 作者: Diskectomy 時間: 2025-3-27 15:13
http://image.papertrans.cn/c/image/221777.jpg作者: onlooker 時間: 2025-3-27 21:15 作者: Polydipsia 時間: 2025-3-27 22:10
https://doi.org/10.1007/978-3-663-05720-8 the latter 3. would cause an increase of intracellular Ca., which in turn would 4. stimulate the contractile proteins to a larger extent than before addition of the drugs. This hypothesis seemed to explain the increase in force of contraction rather well and also the clinically important arrhythmia作者: 集中營 時間: 2025-3-28 04:45 作者: FEAT 時間: 2025-3-28 06:23 作者: upstart 時間: 2025-3-28 10:55 作者: Pert敏捷 時間: 2025-3-28 18:26
Nonradioactive Analysis of Biomoleculesh the increase in the intracellular Na. concentration. It is suppressed in Na. free medium or when Na. is replaced by Li. suggesting that the increase is due to the indirect activation of the Na./Ca. exchange system in the plasma membrane. Dose-response curves for the inotropic effects of ouabain on作者: 玉米 時間: 2025-3-28 20:12
Nonradioactive Analysis of Biomoleculeseems to correlate with the inotropic action, whereas the low affinity ouabain binding is more related to NaK-ATPase inhibition..To further discriminate the two cardiac glycoside binding sites operative in guinea pig heart muscle, erythrosin B, shown to be an inhibitor of the high affinity ouabain bi作者: incision 時間: 2025-3-29 00:02 作者: Nutrient 時間: 2025-3-29 05:39
Contractility of isolated bovine ventricular myocytes is enhanced by intracellular injection of car作者: 輕彈 時間: 2025-3-29 09:09
The electrogenic Na-K pump current and actions of the cardiac glycosides,作者: intangibility 時間: 2025-3-29 14:33 作者: Monocle 時間: 2025-3-29 17:49
Cardiac glycosides with different effects in the heart,作者: Electrolysis 時間: 2025-3-29 21:14
Cardiac glycoside receptors and positive inotropy Evidence for more than one receptor?, the latter 3. would cause an increase of intracellular Ca., which in turn would 4. stimulate the contractile proteins to a larger extent than before addition of the drugs. This hypothesis seemed to explain the increase in force of contraction rather well and also the clinically important arrhythmia作者: 有幫助 時間: 2025-3-30 02:41
Binding sites for ouabain in human and rat erythrocytes and in rat heart cells,s only the bond between C-2 and C-3 of the rhamnose without affecting the steroid moiety. The periodate oxidation provided additional information for assigning a distorted chair conformation or a transient boat conformation for rhamnose in ouabain. It was also established by .H NMR spectroscopy that作者: 容易做 時間: 2025-3-30 05:14
Cardiac glycosides and intracellular Na+, K+, Ca2+,hythmias are present. The increase of intracellular free and bound calcium, which manifests itself functionally as contracture, is believed to be caused at least by two mechanisms: a stimulation of the Na-Ca-exchange and an inhibition of the specific Ca.-activated ATPase in the plasma membrane catal作者: 萬靈丹 時間: 2025-3-30 11:08
Biphasic positive inotropic actions of ouabain on rat, guinea-pig and cat heart: a mathematical dessic action of ouabain a hypothetical model for the mechanism(s) of action of ouabain is discussed. Mathematical description of this model is based on the existence of two different receptor-types for ouabain. It is suggested that sarcolemmal-bound calcium may play an important role in both mechanism作者: frenzy 時間: 2025-3-30 16:18 作者: Camouflage 時間: 2025-3-30 19:35 作者: 排名真古怪 時間: 2025-3-31 00:38 作者: 修飾語 時間: 2025-3-31 03:13
Nonprofit-Organisationen als Arbeitgeberccording to recent observations the activity of the sodium/potassium-ATPase or its concentration, and therefore the concentration of binding sites can increase in some tissues after long term treatment with cardiac glycosides. This might explain the occasionally observed tolerance to digitalis glycosides.作者: arbiter 時間: 2025-3-31 08:36 作者: outskirts 時間: 2025-3-31 10:35 作者: Geyser 時間: 2025-3-31 13:39
H.-J. Guder,Werner Kunz,Sabine Westditions suggested that lowering Ca. has qualitative and quantitative effects. Low Ca. concentrations increased the sensitivities to ouabain and the amplitudes of both the enzyme inhibition and the positive inotropic effects.作者: 捏造 時間: 2025-3-31 21:21
Two receptors for cardiac glycosides in the heart,owever, is only inhibited at toxic glycoside concentrations. Thus, in rat and guinea pig heart there exist at least two different digitalis receptors - the high affinity receptor seems to be coupled to inotropic effects, the low affinity receptor is linked to inhibition of (Na.+K.)-ATPase.作者: 小卷發(fā) 時間: 2025-3-31 23:26
Subclassification of cardiac glycoside receptors,u discovered Na,K-ATPase and since, the mechanism of Na and K transport has been extensively investigated. Several physiological processes are coupled to the Na,K-pump, the identification of this coupling has been demonstrated by blockade of the pump by large doses of cardiac glycosides.作者: 夜晚 時間: 2025-4-1 03:27 作者: 填滿 時間: 2025-4-1 10:03 作者: gerontocracy 時間: 2025-4-1 12:28 作者: 直言不諱 時間: 2025-4-1 15:33
Cardiac Glycosides and sodium/potassium-ATPase,ccording to recent observations the activity of the sodium/potassium-ATPase or its concentration, and therefore the concentration of binding sites can increase in some tissues after long term treatment with cardiac glycosides. This might explain the occasionally observed tolerance to digitalis glycosides.作者: 運動的我 時間: 2025-4-1 19:29
omic issues in today’s China..The China Household Finance Survey has a guiding significance for a realistic strategy adjustment and is also a major breakthrough in the subject’s development at universities. .Li978-3-642-44611-5978-3-642-38151-5
