標(biāo)題: Titlebook: Cardiac Gene Therapy; Methods and Protocol Kiyotake Ishikawa Book 2022Latest edition The Editor(s) (if applicable) and The Author(s), under [打印本頁] 作者: 聯(lián)系 時間: 2025-3-21 16:25
書目名稱Cardiac Gene Therapy影響因子(影響力)
書目名稱Cardiac Gene Therapy影響因子(影響力)學(xué)科排名
書目名稱Cardiac Gene Therapy網(wǎng)絡(luò)公開度
書目名稱Cardiac Gene Therapy網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Cardiac Gene Therapy被引頻次
書目名稱Cardiac Gene Therapy被引頻次學(xué)科排名
書目名稱Cardiac Gene Therapy年度引用
書目名稱Cardiac Gene Therapy年度引用學(xué)科排名
書目名稱Cardiac Gene Therapy讀者反饋
書目名稱Cardiac Gene Therapy讀者反饋學(xué)科排名
作者: VOK 時間: 2025-3-21 20:28
Book 2022Latest editionons in the field.?.Chapter “Direct Reprogramming of Adult Human Cardiac Fibroblasts into Induced Cardiomyocytes Using miRcombo” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com..作者: tariff 時間: 2025-3-22 02:45 作者: 反叛者 時間: 2025-3-22 07:02 作者: 拔出 時間: 2025-3-22 10:37 作者: Dungeon 時間: 2025-3-22 16:55 作者: Dungeon 時間: 2025-3-22 20:14 作者: 諷刺 時間: 2025-3-22 21:14 作者: 未完成 時間: 2025-3-23 05:09
Erfolgreiches Sozialmanagement,15 nucleotides long plus a sugar-ring (LNA, locked nucleid acid) or cholesterol ending (AntagomiR). Modulation of miRNAs might serve as therapeutic targets through miRNA knockdown or overexpression via miRNA mimics. Due to their pleiotropic mode of action and the presence of individual miRNAs in a v作者: Benzodiazepines 時間: 2025-3-23 06:42 作者: 不足的東西 時間: 2025-3-23 11:14 作者: aesthetic 時間: 2025-3-23 15:11 作者: 頭腦冷靜 時間: 2025-3-23 20:32 作者: 愛社交 時間: 2025-3-24 00:47
Nonprofessional Film Performance translation of target mRNA transcripts or affecting cell mRNA stability. Since miRNAs are comprehensively involved in gene regulation, their abnormalities are associated with various human diseases, including cardiovascular disease. Additionally, targeted inhibition of disease-related miRNAs and th作者: TRACE 時間: 2025-3-24 05:11
Nonprofessional Film Performanceon after ischemic heart disease. Previous studies have reported that murine fibroblasts can be directly reprogrammed into iCMs by transient transfection with four miRNAs (miRs-1, 133, 208 and 499 – termed “miRcombo”). While advancement in the knowledge of direct cell reprogramming molecular mechanis作者: encyclopedia 時間: 2025-3-24 09:46
Nonprofits vs. for-Profits Digitalization of genetic mutations associated with cardiac arrhythmia. Human iPSCs can be generated by reprograming of dermal fibroblasts of normal or diseased individuals and be differentiated into cardiac myocytes. Obtaining biopsies from patients afflicted with point mutations causing arrhythmia is often a cu作者: 向下五度才偏 時間: 2025-3-24 12:38
Nonprofits vs. for-Profits Digitalizationral tissue environment. Modified CRISPR/Cas9 systems were developed to be used as guide (g) RNA programmable transcriptional activation platforms (CRISPRa) in vitro and in vivo allowing targeted or multiplexed gene activation studies. We specifically developed these tools to be applied in cardiomyoc作者: Vsd168 時間: 2025-3-24 16:42 作者: 五行打油詩 時間: 2025-3-24 21:06 作者: 赦免 時間: 2025-3-25 00:14
https://doi.org/10.1057/9780230505889y, and little to no pathogenicity, making it highly applicable for gene manipulation, in vivo. However, current AAV9 technology is limited by the lack of strains that can selectively express and elucidate gene function in an atrial- and ventricular-specific manner. In fact, study of gene function in作者: Muscularis 時間: 2025-3-25 04:55
Accountability Elements in Nonprofitse, cardiac-specific promoters provide target tissue specificity, although expression is often debilitated compared to that of ubiquitous promoters. We have previously shown that sarcolipin promoter with an enhancer calsequestrin cis-regulatory module 4 (CRM4) combination has an improved atrial speci作者: aerial 時間: 2025-3-25 09:48 作者: gorgeous 時間: 2025-3-25 13:29 作者: 供過于求 時間: 2025-3-25 19:41 作者: Herbivorous 時間: 2025-3-25 21:30 作者: 變量 時間: 2025-3-26 04:05 作者: 異教徒 時間: 2025-3-26 06:25
Erfolgreiches Verbandsmanagement,site of injection, interventional approach, and type of cardiac circulation at the time of transfer. Randomized clinical trials have suggested that the therapeutic benefits of gene therapy are not as substantial as expected from animal studies. This discordance in results is largely due to gene deli作者: 尋找 時間: 2025-3-26 09:08
AAV-Mediated Somatic Gene Editing for Cardiac and Skeletal Muscle in a Large Animal Model skeletal muscle and myocardial cells. We initially describe the genomic composition of the rAAV-CRISPR vectors used in our lab. Furthermore, we give a step-by-step instruction into the production of recombinant viral vectors with high yields and purity. Lastly we describe the minimally invasive injection regimes to target the myocardium in a pig.作者: 媒介 時間: 2025-3-26 15:55
Kiyotake IshikawaIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts作者: 多嘴多舌 時間: 2025-3-26 20:46
Methods in Molecular Biologyhttp://image.papertrans.cn/c/image/221776.jpg作者: Infirm 時間: 2025-3-26 21:05 作者: 使隔離 時間: 2025-3-27 04:07 作者: STELL 時間: 2025-3-27 08:13 作者: Obligatory 時間: 2025-3-27 10:38 作者: opinionated 時間: 2025-3-27 15:45 作者: 跳脫衣舞的人 時間: 2025-3-27 21:42
Enhancing Cardiomyocyte Transcription Using In Vivo CRISPR/Cas9 Systemsof newly identified gRNA for enhancing transcriptional activity of a selected gene of interest. Additionally, we are providing insights into a downstream application in a dCas9VPR expressing mouse model specifically for cardiomyocyte biology.作者: Amylase 時間: 2025-3-27 22:10
Optimization of Synthesis of Modified mRNA-based therapies to promote cardiac regeneration following myocardial infarction and heart failure. We have also developed and refined an optimized and economical method for synthesis of modRNA. Here, we provide an updated methodology with improved translational efficiency for in vitro and in vivo application.作者: PAD416 時間: 2025-3-28 05:01 作者: Climate 時間: 2025-3-28 07:45
Nonprofessional Film Performanceation, our early findings pave the way toward new therapeutic strategies for cardiac regeneration in humans. This chapter describes methods for inducing direct reprogramming of AHCFs into iCMs through miRcombo transient transfection, showing experiments to perform for assessing iCM generation.作者: DEAWL 時間: 2025-3-28 11:10
Direct Reprogramming of Adult Human Cardiac Fibroblasts into Induced Cardiomyocytes Using miRcomboation, our early findings pave the way toward new therapeutic strategies for cardiac regeneration in humans. This chapter describes methods for inducing direct reprogramming of AHCFs into iCMs through miRcombo transient transfection, showing experiments to perform for assessing iCM generation.作者: 抒情短詩 時間: 2025-3-28 16:07
1064-3745 ation advice from the expertsThis second edition volume expands on the previous edition with updated techniques and discussions on topics such as gene suppression, editing, and reprogramming; cardiac gene therapy vectors and promoters; cardiac gene delivery methods; pulmonary hypertension; and patie作者: Processes 時間: 2025-3-28 19:57 作者: 容易懂得 時間: 2025-3-29 01:58 作者: 流利圓滑 時間: 2025-3-29 06:34
Updates on Cardiac Gene Therapy Research and Methods: Overview of Cardiac Gene Therapy being conducted to close the gap. The second edition of . in . provides protocols for cutting-edge methodologies used in these studies. In this chapter, we discuss recent updates on cardiac gene therapy studies and provide an overview of the chapters in the book.作者: 遠(yuǎn)足 時間: 2025-3-29 09:49 作者: 吹氣 時間: 2025-3-29 14:04 作者: 慢慢流出 時間: 2025-3-29 16:28 作者: CUMB 時間: 2025-3-29 20:19 作者: Physiatrist 時間: 2025-3-30 01:04
Book 2022Latest editionprogramming; cardiac gene therapy vectors and promoters; cardiac gene delivery methods; pulmonary hypertension; and patient screening and measuring the efficacy of cardiac gene therapy. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to t作者: SOBER 時間: 2025-3-30 04:09 作者: Cacophonous 時間: 2025-3-30 10:59 作者: LUDE 時間: 2025-3-30 12:39 作者: folliculitis 時間: 2025-3-30 18:43
Engaging the External Environment,tocols for three different catheter-based antegrade gene delivery techniques in a preclinical large animal model. This is the second edition of this chapter, and it includes modifications we have made over the past several years that further enhance transduction efficacy.作者: 過份艷麗 時間: 2025-3-30 23:59
Der Fachverband Schreinerhandwerk Bayern, approach and provide a protocol for selective retrograde venous injection in a preclinical large animal model. As limited transgene expression frequently hampers generation of reliable proof-of-principle data and thus translation, this technique provides a valuable tool to ensure high myocardial transduction in preclinical research.
