作者: Reclaim 時(shí)間: 2025-3-21 22:18
Bayesian Spatial Survival Modelsworking hypothesis, positive or negative inotropic effects on twitch tension caused by pressure overload hypertrophy, thyrotoxic hypertrophy, isoproterenol, and UDCG. were not accompanied by parallel changes in TIH. Alternative explanations for the relation between peak twitch tension and TIH are explored.作者: 的闡明 時(shí)間: 2025-3-22 03:43 作者: 開(kāi)花期女 時(shí)間: 2025-3-22 08:34 作者: 啜泣 時(shí)間: 2025-3-22 10:02 作者: 結(jié)果 時(shí)間: 2025-3-22 13:21 作者: 結(jié)果 時(shí)間: 2025-3-22 20:53 作者: 哥哥噴涌而出 時(shí)間: 2025-3-23 00:55 作者: 腐敗 時(shí)間: 2025-3-23 03:50 作者: Abrupt 時(shí)間: 2025-3-23 08:25 作者: 熱情贊揚(yáng) 時(shí)間: 2025-3-23 10:35 作者: DRAFT 時(shí)間: 2025-3-23 17:03 作者: Offstage 時(shí)間: 2025-3-23 21:24 作者: Infraction 時(shí)間: 2025-3-23 22:25 作者: 神圣不可 時(shí)間: 2025-3-24 05:06 作者: Tincture 時(shí)間: 2025-3-24 10:17 作者: 搜集 時(shí)間: 2025-3-24 14:06 作者: HEDGE 時(shí)間: 2025-3-24 18:23 作者: 幼兒 時(shí)間: 2025-3-24 22:23
https://doi.org/10.1007/BFb0023313all contributions from membrane-bound cation pumps. The contribution of protein metabolism remains open to question. Calculations show that mitochondrial proton pumping may account for a large fraction of the cardiac basal metabolism. Nevertheless this component remains essentially ill-understood. C作者: Homocystinuria 時(shí)間: 2025-3-24 23:10 作者: 刻苦讀書 時(shí)間: 2025-3-25 07:03
Normal form results for default logic,h subdivisions are often thermodynamically misleading. There is an activation term that relates to Ca . release and retrieval, a work term and a stress or load-dependent heat term. The work and load-dependent energy terms presumably have their origin in the actin-activated myosin ATPase. It can be s作者: 注入 時(shí)間: 2025-3-25 10:53
Deduction with supernormal defaults,xotonic contractile work, depending on the preload, afterload and beat rate in isolated superfused left guinea pig atria. The mitochondrial activity was measured by (1) continuous determination of the O. uptake rate, (2) the rate of .CO. production from labelled glucose or FFA and (3) separate measu作者: 巡回 時(shí)間: 2025-3-25 12:05
Vector Delay Differential Equations,n electrode..Using a diffusion model we eliminated the effect of oxygen storage on the measured time course of oxygen uptake to determine the time constant of mitochondrial “off” kinetics. Two different approaches were followed. In Method 1, two steady-state levels were compared, whereas in Method 2作者: 泥瓦匠 時(shí)間: 2025-3-25 16:50
https://doi.org/10.1007/978-1-4614-3455-9dard one-pulse NMR spectroscopy coupled with conventional biochemical analyses provides information about the average cytosolic concentrations of ATP, creatine phosphate (CrP), creatine (Cr) and H. in the heart. By combining these techniques, we tested the hypothesis that the velocity of the creatin作者: 清晰 時(shí)間: 2025-3-25 22:35 作者: AMBI 時(shí)間: 2025-3-26 01:21
https://doi.org/10.1007/978-3-319-19518-6vary considerably and differences are also found in their myosin composition. In this study a comparison was made between the rate of ATP hydrolysis estimated from the stable maintenance heat rate and the mechanical performance of fibres of type 1, 2 and 3..In the experiments, firstly the force-velo作者: 星球的光亮度 時(shí)間: 2025-3-26 07:45 作者: 注射器 時(shí)間: 2025-3-26 12:33 作者: 奇思怪想 時(shí)間: 2025-3-26 16:42 作者: 任意 時(shí)間: 2025-3-26 20:08
Orthonormal Series and Approximation,rations were realized on representative samples of normotensive rats and spontaneously hypertensive rats (SHR) in compensated stages, as well as in SHR in a state of congestive cardiac failure. Cardiac dynamic measurements were performed under Urethane anaesthesia and open chest conditions. Myosin i作者: 乳白光 時(shí)間: 2025-3-26 23:35
Orthonormal Series and Approximation,The investigations were performed on male rats with renal (Goldblatt II) and spontaneous (Aoki-Okamoto) hypertension at different stages of haemodynamic overload. Two groups of SHR were submitted to intermittent feeding (SHR IF); one group received additionally the .-blocking agent atenolol (50 mg/k作者: 槍支 時(shí)間: 2025-3-27 02:30
Nonparametric Regression for Small Samples, state equation of the intertropomyosin-interaction model of Tawada et al. [35] was extended by introducing the rates of cross-bridge cycling of myofibrils composed of V-1 or V-3 and the concentration of the myosin isoenzymes. Cross-bridge cycling rates of 1.0 or 0.7 were derived for myofibrils comp作者: languid 時(shí)間: 2025-3-27 07:19 作者: 鉗子 時(shí)間: 2025-3-27 12:20
978-3-662-11291-5Springer-Verlag Berlin Heidelberg 1987作者: linguistics 時(shí)間: 2025-3-27 15:49
The mechanism of muscle contraction. Biochemical, mechanical, and structural approaches to elucidate cross-bridges which extend from the myosin filaments and cyclically interact with the actin filaments as ATP is hydrolysed. Current biochemical studies suggest that the myosin cross-bridge exists in two main conformations. In one conformation, which occurs in the absence of MgATP, the cross-bridge 作者: 表被動(dòng) 時(shí)間: 2025-3-27 18:48
Energetics studies of muscles of different typesng muscles. In resting fast-twitch skeletal muscle the chemical potential of ATP obtained from the measured intracellular pH, ATP and inorganic phosphate concentrations and from the ADP concentrations calculated from the position of the creatine kinase equilibrium was ?72 kJ/mol ATP. This high value作者: Picks-Disease 時(shí)間: 2025-3-27 23:06
High energy phosphate of the myocardium: Concentration versus free energy changea free energy and chemical potential respectively, of ATP of about 60 kJ/mol. This energy level does not need to be correlated with tissue ATP content and can also be reached with markedly lower amount of tissue ATP. With graded hypoxia, this energy level drops to 50 to 40 kJ/mol without a correspon作者: Abutment 時(shí)間: 2025-3-28 06:08 作者: 經(jīng)典 時(shí)間: 2025-3-28 07:38
Mechanical determinants of myocardial energy turnoverxperimental result corresponds to predictions from a time varying elastance model of the mechanical and energetic properties of the left ventricle. To assess the validity of this model for cardiac muscle in general, experiments were designed to investigate whether mechanical and energetic behaviour 作者: harangue 時(shí)間: 2025-3-28 10:47
Cardiac energetics and the Fenn effecth subdivisions are often thermodynamically misleading. There is an activation term that relates to Ca . release and retrieval, a work term and a stress or load-dependent heat term. The work and load-dependent energy terms presumably have their origin in the actin-activated myosin ATPase. It can be s作者: 性冷淡 時(shí)間: 2025-3-28 17:50
Cardiac energetics: significance of mitochondriaxotonic contractile work, depending on the preload, afterload and beat rate in isolated superfused left guinea pig atria. The mitochondrial activity was measured by (1) continuous determination of the O. uptake rate, (2) the rate of .CO. production from labelled glucose or FFA and (3) separate measu作者: 創(chuàng)新 時(shí)間: 2025-3-28 21:10
Heat production and oxygen consumption following contraction of isolated rabbit papillary muscle at n electrode..Using a diffusion model we eliminated the effect of oxygen storage on the measured time course of oxygen uptake to determine the time constant of mitochondrial “off” kinetics. Two different approaches were followed. In Method 1, two steady-state levels were compared, whereas in Method 2作者: glisten 時(shí)間: 2025-3-29 01:45
Regulation of heart creatine kinasedard one-pulse NMR spectroscopy coupled with conventional biochemical analyses provides information about the average cytosolic concentrations of ATP, creatine phosphate (CrP), creatine (Cr) and H. in the heart. By combining these techniques, we tested the hypothesis that the velocity of the creatin作者: Catheter 時(shí)間: 2025-3-29 03:40 作者: Interlocking 時(shí)間: 2025-3-29 07:15
ATPase activity of intact single muscle fibres of Xenopus laevis is related to the rate of force redvary considerably and differences are also found in their myosin composition. In this study a comparison was made between the rate of ATP hydrolysis estimated from the stable maintenance heat rate and the mechanical performance of fibres of type 1, 2 and 3..In the experiments, firstly the force-velo作者: 狂怒 時(shí)間: 2025-3-29 12:48
Developmental differences in myocardial ATP metabolismemia in neonatal and adult hearts. Hypothermia during ischaemia protected isolated adult and newborn hearts against ATP decline. Reperfusion after normothermic ischaemia resulted in higher ATP levels in newborn hearts with less release of ATP-catabolites. During normoxia adult hearts released mainly作者: EVADE 時(shí)間: 2025-3-29 19:22
The effects of acute and chronic inotropic interventions on tension independent heat of rabbit papilExperiments were designed to test the working hypothesis that changes in peak twitch tension caused by pharmacological agents or changing haemodynamic conditions are accompanied by parallel changes in the tension independent heat (TIH) signal associated with Ca. cycling. We isolated the TIH signal b作者: tendinitis 時(shí)間: 2025-3-29 20:36 作者: hemophilia 時(shí)間: 2025-3-30 02:24
Chronic cardiac reactions. II. Mechanical and energetic consequences of myocardial transformation verations were realized on representative samples of normotensive rats and spontaneously hypertensive rats (SHR) in compensated stages, as well as in SHR in a state of congestive cardiac failure. Cardiac dynamic measurements were performed under Urethane anaesthesia and open chest conditions. Myosin i作者: infelicitous 時(shí)間: 2025-3-30 07:57 作者: Compassionate 時(shí)間: 2025-3-30 09:20 作者: extinguish 時(shí)間: 2025-3-30 13:56 作者: 腐爛 時(shí)間: 2025-3-30 17:14 作者: Fsh238 時(shí)間: 2025-3-30 23:39
The mechanism of muscle contraction. Biochemical, mechanical, and structural approaches to elucidaten and myosin in solution, the cross-bridge cycles back and forth between the weak-binding and strong-binding conformations. Assuming a close correlation between the behaviour of isolated proteins in solution and the cross-bridge action in muscle, Eisenberg and Greene [12] have developed a model for
