標題: Titlebook: Cardiac Adaptation in Heart Failure; Risks due to myocard J. Holtz,H. Drexler,H. Just Conference proceedings 1992 Dr. Dietrich Steinkopff V [打印本頁] 作者: 出租車 時間: 2025-3-21 19:33
書目名稱Cardiac Adaptation in Heart Failure影響因子(影響力)
書目名稱Cardiac Adaptation in Heart Failure影響因子(影響力)學科排名
書目名稱Cardiac Adaptation in Heart Failure網絡公開度
書目名稱Cardiac Adaptation in Heart Failure網絡公開度學科排名
書目名稱Cardiac Adaptation in Heart Failure被引頻次
書目名稱Cardiac Adaptation in Heart Failure被引頻次學科排名
書目名稱Cardiac Adaptation in Heart Failure年度引用
書目名稱Cardiac Adaptation in Heart Failure年度引用學科排名
書目名稱Cardiac Adaptation in Heart Failure讀者反饋
書目名稱Cardiac Adaptation in Heart Failure讀者反饋學科排名
作者: Senescent 時間: 2025-3-21 21:14 作者: STANT 時間: 2025-3-22 03:11 作者: craving 時間: 2025-3-22 08:25
Michael J. Grimble,Pawe? Majeckitive failure. Catecholamines have long been implicated in the pathogenesis of myocardial hypertrophy, however, it is very difficult to sort out catecholamine mechanisms in vivo. We have developed a cell-culture model which excludes hemodynamic effects and allows the assignment of receptor specificit作者: 娘娘腔 時間: 2025-3-22 12:43
Michael J. Grimble,Pawe? Majeckiin a precise developmental and spatial program and are up-regulated, in the adult heart, by ischemia or a hemodynamic burden. The accumulation of trophic factors after aortic banding supports the hypothesis that autocrine or paracrine pathways might function to mediate, in part, the consequences of 作者: Albinism 時間: 2025-3-22 14:09 作者: Albinism 時間: 2025-3-22 17:34
https://doi.org/10.1007/3-540-07945-9rdial contractile behaviour and cardiac pump function in a novel manner, mainly by influencing the duration of contraction and the onset of relaxation but without major effect on early systolic contractile characteristics. These effects are mediated by the release of at least two diffusible substanc作者: 阻礙 時間: 2025-3-22 23:51 作者: 泥土謙卑 時間: 2025-3-23 02:25
S. P. Lin,W. R. C. Phillips,D. T. Valentineling dilated cardio-myopathic hearts at a stimulation rate of 60 beats per minute (37°C). This frequency was chosen because analysis of the force-frequency relation showed significant differences in isometric force between failing and nonfailing human myocardium at 60 beats per minute and at higher 作者: 送秋波 時間: 2025-3-23 08:23
https://doi.org/10.1007/978-3-642-85084-4ly within and among cells. The SR can also generate spontaneous Ca. oscillations (S-CaOs), i.e., not triggered by sarcolemmal depolarization. The local increase in Ca. due to S-CaOs is equivalent to that induced by an AP. Heterogeneity of diastolic Ca. caused by asynchronous S-CaOs among cells withi作者: podiatrist 時間: 2025-3-23 09:57 作者: 中國紀念碑 時間: 2025-3-23 14:35
Mixed-Integer Nonlinear Programming,trant mechanisms also appear to be operative under a wide variety of pathophysiologic conditions. For example, results obtained using three-dimensional (3D) mapping from 232 simultaneous sites in the feline heart in vivo revealed that nonreentrant or focal mechanisms were prominent during both ische作者: 眼界 時間: 2025-3-23 19:04
https://doi.org/10.1007/0-387-32995-1ee [Ca.].. It is well documented that elevated [Ca.]. may produce SR release of Ca. and oscillations of membrane potential, thereby leading to triggered or spontaneous ectopic activity. The relation among elevated free [Ca.]., electrical cell-to-cell coupling, conduction slowing, and reentrant arrhy作者: CIS 時間: 2025-3-23 23:26
Nonseparable Integer Programming,dling results in prolongation of the calcium transient and in a biphasic calcium transient with prominent late component. In the present studies, the mechanical correlates of abnormal calcium handling were investigated in the hypertrophied human left ventricle by analysis of: 1) isovolumic left-vent作者: 叢林 時間: 2025-3-24 03:16 作者: 過于平凡 時間: 2025-3-24 08:20 作者: PLIC 時間: 2025-3-24 14:40
Nonlinear Lagrangian and Strong Duality,ium, in areas between and surrounding cardiac myocytes. Cardiac fibroblasts are responsible for the synthesis of extracellular matrix proteins such as fibrillar collagen types I and III, basement membrane type IV collagen, fibronectin, and laminin. In addition to its role in muscle development and m作者: Foregery 時間: 2025-3-24 17:47
,Constrained Polynomial 0–1 Programming,ay be due to alterations in cardiac gene expression, resulting in a more fetal-like myocyte phenotype with a fragile Ca.-homeostasis. Depressed expression of the sarcoplasmic reticulum Ca.-ATPase is the hallmark of this overload phenotype, contributing to prolonged cytosolic Ca.-transients, disturbe作者: Lice692 時間: 2025-3-24 19:05 作者: Palter 時間: 2025-3-25 00:41 作者: Hemodialysis 時間: 2025-3-25 03:58 作者: 口味 時間: 2025-3-25 10:06
Afterdepolarizations and triggered activity,tials. Ca channels are usually responsible for the inward current for EAD’s, and cellular Ca overload is not related. These afterdepolarizations have characteristics that suggest their etiological role in certain arrhythmias found in heart failure.作者: nuclear-tests 時間: 2025-3-25 12:15
Conference proceedings 1992this adaptive hypertrophic process is rather complex and may include problematic facets. The adaptive hypertrophy includes proliferation of the nonmyocyte cardiac cells as well as substantial alterations in the phenotype of the growing myocytes due to differential changes in gene expression.作者: Flatter 時間: 2025-3-25 18:02 作者: 發(fā)酵 時間: 2025-3-25 21:06 作者: HERTZ 時間: 2025-3-26 01:06
Michael J. Grimble,Pawe? Majeckihich transmits competence to the cell to be transformed. The permanent modifications occur at all cellular levels including the sarcomere, sarcolemma, energy metabolism, and extra-cellular matrix, but they are species-specific and differ in the ventricles and the atria.作者: 建筑師 時間: 2025-3-26 07:29
Biological adaptation of the myocardium to a permanent change in loading conditions,hich transmits competence to the cell to be transformed. The permanent modifications occur at all cellular levels including the sarcomere, sarcolemma, energy metabolism, and extra-cellular matrix, but they are species-specific and differ in the ventricles and the atria.作者: 搖曳 時間: 2025-3-26 08:50
Biological adaptation of the myocardium to a permanent change in loading conditions,rocess is randomly governed and results in at least one thermodynamical benefit: to be adaptational and to induce several changes in gene expression. Some of these changes are detrimental, some can even be useless. The cascade of events which finally leads to a permanent modification of the genetic 作者: Pageant 時間: 2025-3-26 13:34 作者: insurrection 時間: 2025-3-26 18:21
Sympathetic modulation of the cardiac myocyte phenotype: studies with a cell-culture model of myocative failure. Catecholamines have long been implicated in the pathogenesis of myocardial hypertrophy, however, it is very difficult to sort out catecholamine mechanisms in vivo. We have developed a cell-culture model which excludes hemodynamic effects and allows the assignment of receptor specificit作者: 異端邪說下 時間: 2025-3-26 23:37 作者: 貝雷帽 時間: 2025-3-27 02:02
Signaling mechanisms for the activation of an embryonic gene program during the hypertrophy of cardponse. The induction of the atrial natriuretic factor gene (ANF) is one of the most conserved features of ventricular hypertrophy, occurring in multiple species (mouse, rat, hamster, canine, and human) in response to diverse stimuli (hormonal, mechanical, pressure/volume overload, genetic, IHSS, hyp作者: CT-angiography 時間: 2025-3-27 05:43
Endothelial modulation of myocardial contraction: mechanisms and potential relevance in cardiac disrdial contractile behaviour and cardiac pump function in a novel manner, mainly by influencing the duration of contraction and the onset of relaxation but without major effect on early systolic contractile characteristics. These effects are mediated by the release of at least two diffusible substanc作者: 商談 時間: 2025-3-27 10:58
The regulation of calcium cycling in stressed hearts,t which it is removed in control, thyrotoxic and pressure-overloaded rabbit hearts. Experiments were carried out at 30°C. In control rabbit hearts 41.0 ± 7.0 nmoles/g Ca. was released into the cytosol for each beat, while the rate at which the Ca. was removed from the cytosol was 24.4 ± 4.4 nmoles/g作者: 猜忌 時間: 2025-3-27 13:51
Energetics of calcium cycling in nonfailing and failing human myocardium,ling dilated cardio-myopathic hearts at a stimulation rate of 60 beats per minute (37°C). This frequency was chosen because analysis of the force-frequency relation showed significant differences in isometric force between failing and nonfailing human myocardium at 60 beats per minute and at higher 作者: Cardiac 時間: 2025-3-27 20:39
Spontaneous sarcoplasmic reticulum Ca2+ release leads to heterogeneity of contractile and electricaly within and among cells. The SR can also generate spontaneous Ca. oscillations (S-CaOs), i.e., not triggered by sarcolemmal depolarization. The local increase in Ca. due to S-CaOs is equivalent to that induced by an AP. Heterogeneity of diastolic Ca. caused by asynchronous S-CaOs among cells withi作者: RLS898 時間: 2025-3-28 01:13
Afterdepolarizations and triggered activity,on. The delayed afterdepolarization (DAD) arises from the resting potential after full repolarization of an action potential and it may reach threshold for activation. It is favored by cellular Ca overload, and rapid preceding activation rates. The inward current generating the DAD is caused by one 作者: 積習已深 時間: 2025-3-28 04:26
The contribution of nonreentrant mechanisms to malignant ventricular arrhythmias,trant mechanisms also appear to be operative under a wide variety of pathophysiologic conditions. For example, results obtained using three-dimensional (3D) mapping from 232 simultaneous sites in the feline heart in vivo revealed that nonreentrant or focal mechanisms were prominent during both ische作者: 賠償 時間: 2025-3-28 08:15
The potential role of Ca2+ for electrical cell-to-cell uncoupling and conduction block in myocardiaee [Ca.].. It is well documented that elevated [Ca.]. may produce SR release of Ca. and oscillations of membrane potential, thereby leading to triggered or spontaneous ectopic activity. The relation among elevated free [Ca.]., electrical cell-to-cell coupling, conduction slowing, and reentrant arrhy作者: 約會 時間: 2025-3-28 10:57 作者: Favorable 時間: 2025-3-28 15:05
Diastolic dysfunction in pressure-overload hypertrophy and its modification by angiotensin II: currning normal myocardial fiber stress and shortening in systole. A deleterious consequence of pressure-overload hypertrophy is the prolongation of Ca.-sensitive force inactivation (impaired myocardial relaxation) which is related to intrinsic alterations in cytosolic Ca. transport and reuptake in dias作者: 表狀態(tài) 時間: 2025-3-28 22:35
Mechanisms of cardiac growth. The role of the renin-angiotensin system,ft ventricle. As cardiac myocytes cannot divide, they increase in mass and volume, probably by activating second messengers and proto-oncogenes involved in cellular differentiation and proliferation. Various mechanisms, such as pressure overload and angiotensin II (Ang II), have been proposed to tri作者: 流利圓滑 時間: 2025-3-29 01:53 作者: ROOF 時間: 2025-3-29 06:28 作者: CIS 時間: 2025-3-29 10:30 作者: 反叛者 時間: 2025-3-29 11:28
Michael J. Grimble,Pawe? Majeckiore, we observed the activation of mitogen activated protein (MAP) kinase by myocyte stretching. This result suggest that MAP kinase activation might increase the efficiency of protein synthesis in ribosomes induced by mechanical stimuli.作者: conjunctivitis 時間: 2025-3-29 18:09
Michael J. Grimble,Pawe? Majecking transcription of the .-MHC isogene. . adrenergic stimulation of the cultured cardiac myocytes also results in a modest degree of hypertrophy, however, this effect may be dependent upon myocyte contractile activity and may involve, at least in part, the non-muscle cells present in the culture syst作者: BRIDE 時間: 2025-3-29 21:52 作者: milligram 時間: 2025-3-30 02:54
Optical mixing in atomic vapors,ion during hypertrophy and the initial stages of cardiogenesis. A combination of co-transfection, microinjection, and transgenic approaches has been coupled to well characterized cultured cell systems and in vivo murine models employing normal and transgenic mice. The microinjection of oncogenic RAS作者: 可轉變 時間: 2025-3-30 07:02
https://doi.org/10.1007/3-540-07945-9owth, interact with other cardiac hormones, and via EDRF inhibit platelet adhesion to endothelial surfaces. The release of the endothelial factors is regulated by stimuli such as circulating neurohumoral substances, increased flow, products of platelet aggregation, and endogenous peptides stored in 作者: 文藝 時間: 2025-3-30 09:32
https://doi.org/10.1007/978-3-642-85084-4 an increase in the amount of calcium liberated into the cytosol (39%) and the rate of calcium removal (31%). This increase is correlated with an increase in the mRNA and protein expression for the SR Ca. ATPase as well as the mRNA for the ryanodine receptor. Calsequestrin mRNA was unchanged in all 作者: 種子 時間: 2025-3-30 15:12 作者: 光滑 時間: 2025-3-30 18:17 作者: 的事物 時間: 2025-3-30 23:06 作者: allergy 時間: 2025-3-31 02:57 作者: 發(fā)起 時間: 2025-3-31 06:13
Nonseparable Integer Programming,lted in a slow and dyssynchronous left-ventricular relaxation pattern, as evident from a prolongation of the time constant of left-ventricular pressure decay from 46.6 ± 12.5 to 73.2 ± 23.3 ms (p < 0.01), and from the development of a convex downward negative dP/dt upstroke pattern. Abnormal diastol作者: Hectic 時間: 2025-3-31 13:01
Nonseparable Integer Programming,n and activity in animal models of hypertrophy, including the aortic-banded rat with compensatory pressure-overload hypertrophy and rats with post-infarction remodeling. In the beating, isovolumic aortic-banded rat heart, the increased intracardiac activation of angiotensin I to II has been shown to作者: 大方一點 時間: 2025-3-31 16:17 作者: Limited 時間: 2025-3-31 20:20
