標(biāo)題: Titlebook: Carbohydrates as Drugs; Peter H. Seeberger,Christoph Rademacher Book 2014 Springer International Publishing Switzerland 2014 Anti-Influenz [打印本頁] 作者: broach 時(shí)間: 2025-3-21 18:03
書目名稱Carbohydrates as Drugs影響因子(影響力)
書目名稱Carbohydrates as Drugs影響因子(影響力)學(xué)科排名
書目名稱Carbohydrates as Drugs網(wǎng)絡(luò)公開度
書目名稱Carbohydrates as Drugs網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Carbohydrates as Drugs被引頻次
書目名稱Carbohydrates as Drugs被引頻次學(xué)科排名
書目名稱Carbohydrates as Drugs年度引用
書目名稱Carbohydrates as Drugs年度引用學(xué)科排名
書目名稱Carbohydrates as Drugs讀者反饋
書目名稱Carbohydrates as Drugs讀者反饋學(xué)科排名
作者: catagen 時(shí)間: 2025-3-21 23:58
978-3-319-34537-6Springer International Publishing Switzerland 2014作者: Gastric 時(shí)間: 2025-3-22 01:32
Peter H. Seeberger,Christoph RademacherOverview chapters introduce the newcomer to the topic covered.Series covers hot topics of frontier research summarized by reputed scientists in the field.Volumes are useful and of relevance for a long作者: stressors 時(shí)間: 2025-3-22 07:07
Topics in Medicinal Chemistryhttp://image.papertrans.cn/c/image/221546.jpg作者: LUT 時(shí)間: 2025-3-22 09:18 作者: inflame 時(shí)間: 2025-3-22 15:56
Growth of , in Seawater Culture Mediumf carbohydrate mimetic reported to date with two marketed drugs and several in clinical development. Since their first isolation in the 1960s iminosugars have captured the imagination of both synthetic and medicinal chemists alike with recent therapeutic developments highlighting the need for improv作者: inflame 時(shí)間: 2025-3-22 17:19 作者: Heresy 時(shí)間: 2025-3-22 22:31
Obtention of Auxotrophic Mutants in ,ed primarily by the sodium-dependent glucose transporter 2 (SGLT2) as the glomerular filtrate flows down the renal tubules. SGLT2 inhibitors inhibit this transporter leading to the loss of a significant fraction of the filtered glucose. The resulting glucosuria is of sufficient magnitude to reduce d作者: ascetic 時(shí)間: 2025-3-23 05:10
Martin Ramirez-Orozco,Jose Luis Ochoaranoside residues in glycoconjugates, and by presenting multiple binding sites, within one galectin or by forming dimers or multimers, they can cross-link glycoproteins and form galectin-glycoprotein lattices. Such lattices formed on the cell surface or in vesicles have been shown to control, for ex作者: 弄污 時(shí)間: 2025-3-23 08:59 作者: Intervention 時(shí)間: 2025-3-23 11:25 作者: Exploit 時(shí)間: 2025-3-23 13:52 作者: 泛濫 時(shí)間: 2025-3-23 20:36
Carbohydrates as Drugs978-3-319-08675-0Series ISSN 1862-2461 Series E-ISSN 1862-247X 作者: pulmonary 時(shí)間: 2025-3-24 00:24
Book 2014roughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known 作者: 松軟 時(shí)間: 2025-3-24 03:39 作者: 油膏 時(shí)間: 2025-3-24 09:09
Obtention of Auxotrophic Mutants in ,d selective .SGLT2 inhibitor with an EC. for .SGLT2 of 1.0?nM and 1,200-fold selectivity over .SGLT1. Dapagliflozin produced glucosuria in normal Sprague Dawley rats in a dose-dependent fashion. Moreover, a 0.1?mg/kg oral dose reduced blood glucose levels by as much as 55% in rats that had been made作者: Delude 時(shí)間: 2025-3-24 14:20
Martin Ramirez-Orozco,Jose Luis Ochoa been important in elucidating galectin-3 mechanisms, including galectin-3 trafficking, cancer, inflammation, fibrosis, and angiogenesis. Medically relevant models using the galectin-3 modulators in characterizing macrophage alternative activation and chronic inflammation, myofibroblast activation a作者: rectocele 時(shí)間: 2025-3-24 16:31
Klaus Wolf,Karin Breunig,Gerold Barthdhesion can be attributed to structural differences in the mannosidic receptors than based on amino acid variance in FimH. The crystal structure of FimH in complex with oligomannoside-3 presented a breakthrough that enhanced the rational design of mannose-based anti-adhesives against FimH. In this o作者: 轉(zhuǎn)換 時(shí)間: 2025-3-24 20:22
Statistical Models Based Algorithmsake and processing of the antigen and resulted in a five-fold higher mannan-specific antibody response together with a cytokine profile appropriate for an antifungal vaccine. When the same trisaccharide was conjugated to a T-cell peptide derived from . cell-wall protein, the resulting glycopeptide–t作者: alcoholism 時(shí)間: 2025-3-25 01:56 作者: FRET 時(shí)間: 2025-3-25 04:06
Discovery and Development of Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Dapagd selective .SGLT2 inhibitor with an EC. for .SGLT2 of 1.0?nM and 1,200-fold selectivity over .SGLT1. Dapagliflozin produced glucosuria in normal Sprague Dawley rats in a dose-dependent fashion. Moreover, a 0.1?mg/kg oral dose reduced blood glucose levels by as much as 55% in rats that had been made作者: 柔軟 時(shí)間: 2025-3-25 08:21 作者: observatory 時(shí)間: 2025-3-25 11:43 作者: legacy 時(shí)間: 2025-3-25 17:32
The Evolution of a Glycoconjugate Vaccine for ,,ake and processing of the antigen and resulted in a five-fold higher mannan-specific antibody response together with a cytokine profile appropriate for an antifungal vaccine. When the same trisaccharide was conjugated to a T-cell peptide derived from . cell-wall protein, the resulting glycopeptide–t作者: 忙碌 時(shí)間: 2025-3-25 20:42
1862-2461 eractions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known 978-3-319-34537-6978-3-319-08675-0Series ISSN 1862-2461 Series E-ISSN 1862-247X 作者: Spartan 時(shí)間: 2025-3-26 03:09
1862-2461 in the field.Volumes are useful and of relevance for a longMedicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need fo作者: 恫嚇 時(shí)間: 2025-3-26 04:29
Klaus Wolf,Karin Breunig,Gerold Barthpossible target molecules. In a personal selection the authors demonstrate how to make use of carbohydrates as a starting point for Pd-catalyzed coupling reactions to obtain .-glycosides, how to link carbohydrate and cyclopropane chemistry, and how efficient carbopalladation cascades fuse carbohydrates with aromatic units.作者: invade 時(shí)間: 2025-3-26 10:12
Preparation of Total DNA from ,itfalls in docking of carbohydrates are described. Practical examples explain the use of docking methods for the rational design of carbohydrate-based inhibitors as well as the prediction of carbohydrate binding sites.作者: 有毛就脫毛 時(shí)間: 2025-3-26 14:32 作者: 在駕駛 時(shí)間: 2025-3-26 17:38
Computational Docking as a Tool for the Rational Design of Carbohydrate-Based Drugs,itfalls in docking of carbohydrates are described. Practical examples explain the use of docking methods for the rational design of carbohydrate-based inhibitors as well as the prediction of carbohydrate binding sites.作者: 有花 時(shí)間: 2025-3-26 23:46
Multi-Objective Branch and Boundcellular targets, and (2) the lectins are targets of the so-called anti-virulence therapy and therefore a reduced appearance of resistances towards lectin-directed drugs can be anticipated. In this review, the recent development of carbohydrate-based inhibitors against both lectins is summarized with a main focus on small molecules.作者: 嘴唇可修剪 時(shí)間: 2025-3-27 03:04
Carbohydrate-Based Anti-Virulence Compounds Against Chronic , Infections with a Focus on Small Molecellular targets, and (2) the lectins are targets of the so-called anti-virulence therapy and therefore a reduced appearance of resistances towards lectin-directed drugs can be anticipated. In this review, the recent development of carbohydrate-based inhibitors against both lectins is summarized with a main focus on small molecules.作者: incubus 時(shí)間: 2025-3-27 08:34
Book 2014. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-wor作者: 色情 時(shí)間: 2025-3-27 12:32 作者: Anterior 時(shí)間: 2025-3-27 16:54 作者: nonsensical 時(shí)間: 2025-3-27 20:59
Computational Docking as a Tool for the Rational Design of Carbohydrate-Based Drugs,so significant limitations and care needs to be taken when evaluating the docking results. In this chapter the challenges, limitations, and possible pitfalls in docking of carbohydrates are described. Practical examples explain the use of docking methods for the rational design of carbohydrate-based作者: 攝取 時(shí)間: 2025-3-27 22:16
Discovery and Development of Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Dapaged primarily by the sodium-dependent glucose transporter 2 (SGLT2) as the glomerular filtrate flows down the renal tubules. SGLT2 inhibitors inhibit this transporter leading to the loss of a significant fraction of the filtered glucose. The resulting glucosuria is of sufficient magnitude to reduce d作者: indubitable 時(shí)間: 2025-3-28 04:46 作者: 永久 時(shí)間: 2025-3-28 08:22
