標(biāo)題: Titlebook: Cancer and Zebrafish; Mechanisms, Techniqu David M. Langenau Book 2016 The Editor(s) (if applicable) and The Author(s), under exclusive lic [打印本頁(yè)] 作者: 航天飛機(jī) 時(shí)間: 2025-3-21 16:50
書(shū)目名稱Cancer and Zebrafish影響因子(影響力)
書(shū)目名稱Cancer and Zebrafish影響因子(影響力)學(xué)科排名
書(shū)目名稱Cancer and Zebrafish網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Cancer and Zebrafish網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Cancer and Zebrafish被引頻次
書(shū)目名稱Cancer and Zebrafish被引頻次學(xué)科排名
書(shū)目名稱Cancer and Zebrafish年度引用
書(shū)目名稱Cancer and Zebrafish年度引用學(xué)科排名
書(shū)目名稱Cancer and Zebrafish讀者反饋
書(shū)目名稱Cancer and Zebrafish讀者反饋學(xué)科排名
作者: 掃興 時(shí)間: 2025-3-21 23:49 作者: 合乎習(xí)俗 時(shí)間: 2025-3-22 04:08
https://doi.org/10.1007/b102415r genomic noise and ultimately uncover central drivers of malignancy. Finally, I discuss downstream analytic tools, including network analysis, that can help to organize the alterations into coherent biological frameworks that can then be investigated further.作者: choroid 時(shí)間: 2025-3-22 05:14
The Toolbox for Conditional Zebrafish Cancer Modelseactive proteins will enable the development of even more sophisticated zebrafish cancer models. Here, we introduce this growing toolbox of conditional transgenic approaches, discuss its current application in zebrafish cancer models and provide an outlook on future perspectives.作者: precede 時(shí)間: 2025-3-22 11:52 作者: 笨重 時(shí)間: 2025-3-22 15:30 作者: 笨重 時(shí)間: 2025-3-22 17:18
Uncharted Waters: Zebrafish Cancer Models Navigate a Course for Oncogene Discoverygh the functional analysis of cancer genomes. Now in the second decade, zebrafish cancer models are poised for even faster growth as they are used in high-throughput genetic analyses to elucidate key mechanisms underlying critical cancer phenotypes.作者: 靈敏 時(shí)間: 2025-3-23 00:54
0065-2598 ious cancers, including leukemia, melanoma, pancreatic and lThisvolume focuses on defining the unique attributes of using the?zebrafish cancermodel for discovering important pathways and potential drug targets for thetreatment of human cancers. Using the?zebrafish model, the volumeexplores?oncogene 作者: MILK 時(shí)間: 2025-3-23 02:03
Selected Applications of Geostatical Methods open the door for complex genetic analysis of tumorigenesis. In this chapter, we will describe the various technologies for conducting genome editing in zebrafish with special emphasis on the approaches to inactivate genes.作者: 啪心兒跳動(dòng) 時(shí)間: 2025-3-23 07:28 作者: insecticide 時(shí)間: 2025-3-23 11:15
Approaches to Inactivate Genes in Zebrafish open the door for complex genetic analysis of tumorigenesis. In this chapter, we will describe the various technologies for conducting genome editing in zebrafish with special emphasis on the approaches to inactivate genes.作者: heartburn 時(shí)間: 2025-3-23 16:56 作者: 只有 時(shí)間: 2025-3-23 20:22
Parameters of Position of Geosetsgh the functional analysis of cancer genomes. Now in the second decade, zebrafish cancer models are poised for even faster growth as they are used in high-throughput genetic analyses to elucidate key mechanisms underlying critical cancer phenotypes.作者: Pelago 時(shí)間: 2025-3-23 22:44 作者: Alpha-Cells 時(shí)間: 2025-3-24 05:51 作者: 蚊帳 時(shí)間: 2025-3-24 06:47
https://doi.org/10.1007/b102415pounds to the clinic, especially through the repurposing of FDA-approved drugs. Future technological advancements in automation and high-powered imaging, as well as the development and characterization of new mutant and transgenic lines, will expand the scope of chemical genetics in zebrafish.作者: 有權(quán) 時(shí)間: 2025-3-24 12:34 作者: 奴才 時(shí)間: 2025-3-24 17:40
Introducing Geostatistical Methodshe epigenome becomes repatterned in cancer and (2) which of these changes are cancer-causing. Zebrafish provide a tractable in vivo system to monitor the epigenome during transformation and to identify epigenetic drivers of cancer. In this chapter, we review principles of cancer epigenetics and disc作者: 改變 時(shí)間: 2025-3-24 23:05 作者: 熒光 時(shí)間: 2025-3-25 02:05
Parameters of Position of Geosetsival and migration can be tested by simply adding the compound into the water of living embryos. Therefore the zebrafish model offers the opportunity to gain more knowledge on cancer angiogenesis and metastasis in vivo with the final aim of providing new translational insights into therapeutic appro作者: 龍卷風(fēng) 時(shí)間: 2025-3-25 04:03 作者: nuclear-tests 時(shí)間: 2025-3-25 08:29 作者: 沖擊力 時(shí)間: 2025-3-25 12:59
Selected Applications of Geostatical Methodsling and sorting, microfluidic systems for imaging and drug treatment, and image acquisition and analysis. Examples will be given of employment of these technologies within the fields of toxicology research and cancer research.作者: 姑姑在炫耀 時(shí)間: 2025-3-25 17:51
Group transfer polymerizations,research and additionally, advances in zebrafish-based high-throughput drug screening promise to hasten the discovery of novel leukemia therapeutics. To date, investigators have accumulated knowledge of the genetic underpinnings critical to leukemic transformation and treatment resistance and withou作者: CLIFF 時(shí)間: 2025-3-25 23:26
New Methods of Polymer Synthesis the functional significance of potential driver genes. Using the unique strengths of the zebrafish model organisms with the wealth of cellular and molecular tools currently available, zebrafish RMS models provide a powerful in vivo system for which to study RMS tumorigenesis.作者: 是貪求 時(shí)間: 2025-3-26 00:33 作者: thrombus 時(shí)間: 2025-3-26 04:53 作者: TAIN 時(shí)間: 2025-3-26 11:01
Transcriptomic Analyses in Zebrafish Cancer Models for Global Gene Expression and Pathway Discoverytomic tools have also proven effective in the development and the validation of specific assays for chemical compound screening. In the future, other genomic tools, such as epigenetic, proteomic and metabolomic tools will likely be incorporated into zebrafish cancer studies, further refining our und作者: 滔滔不絕地講 時(shí)間: 2025-3-26 13:59 作者: Felicitous 時(shí)間: 2025-3-26 20:14
Lymphatics, Cancer and Zebrafishportant contributions to our understanding of the processes of lymphatic vessel sprouting from veins and the mechanisms by which lymphatic precursors remodel into mature vessels. To date, zebrafish have not been used to directly model tumor lymphangiogenesis. In this chapter we will summarise the co作者: 嚙齒動(dòng)物 時(shí)間: 2025-3-26 22:21
Imaging Cancer Angiogenesis and Metastasis in a Zebrafish Embryo Modelival and migration can be tested by simply adding the compound into the water of living embryos. Therefore the zebrafish model offers the opportunity to gain more knowledge on cancer angiogenesis and metastasis in vivo with the final aim of providing new translational insights into therapeutic appro作者: LUMEN 時(shí)間: 2025-3-27 05:03 作者: Flawless 時(shí)間: 2025-3-27 06:31
The Zebrafish Xenograft Platform: Evolution of a Novel Cancer Model and Preclinical Screening Toolmary patient material by virtue of the relatively low number of cells required for each embryo (between 50 and 300 cells), the absence of an adaptive immune system in the early zebrafish embryo, and the short experimental timeframe (5–7 days). Following xenotransplantation into the fish, cells can b作者: CRUDE 時(shí)間: 2025-3-27 11:33
Automation of Technology for Cancer Researchling and sorting, microfluidic systems for imaging and drug treatment, and image acquisition and analysis. Examples will be given of employment of these technologies within the fields of toxicology research and cancer research.作者: LITHE 時(shí)間: 2025-3-27 16:41 作者: FLAT 時(shí)間: 2025-3-27 19:37 作者: MENT 時(shí)間: 2025-3-28 00:04 作者: HUMP 時(shí)間: 2025-3-28 05:46
Selected Applications of Geostatical Methodspressors at the spatial and temporal level. Methods such as the Gal4/UAS or the Cre/lox systems paved the way to the development of elegant tumor models, which are now being used to study cancer cell biology, clonal evolution, identification of cancer stem cells and anti-cancer drug screening. Combi作者: FLAT 時(shí)間: 2025-3-28 06:26
Selected Applications of Geostatical Methods. Zebrafish is a powerful model for studying tumorigenesis and has been successfully exploited in drug discovery. According to the zebrafish reference genome, 82 % of disease-associated genes in the Online Mendelian Inheritance in Man (OMIM) database have clear zebrafish orthologues. Using a variety作者: 使長(zhǎng)胖 時(shí)間: 2025-3-28 11:49
Introducing Geostatistical Methods and tumors develop late in life. Functional inactivation of tumor suppressors is a crucial step in cancer progression and more and more tumor suppressor genes are being studied in zebrafish. Most often tumor suppressors have been inactivated by reverse genetics approaches using targeted disruption.作者: 積云 時(shí)間: 2025-3-28 14:57
https://doi.org/10.1007/b102415n developmental programs and disease, and simultaneously provides a platform for the discovery of novel therapeutics. The zebrafish is an advantageous model for in vivo high-throughput small molecule screening due to translational appeal, high fecundity, and a unique set of developmental characteris作者: 即席 時(shí)間: 2025-3-28 21:00
https://doi.org/10.1007/b102415insight into the mechanisms of tumorigenesis and the there are many techniques for analyzing the genomes of these tumors. Here, I present an overview of the available technologies for analyzing tumor genomes in the zebrafish, including array based methods as well as next-generation sequencing techno作者: confide 時(shí)間: 2025-3-29 00:24 作者: Concerto 時(shí)間: 2025-3-29 03:37
Introducing Geostatistical Methodsn, and studies using model organisms such as zebrafish provide an opportunity to address these important questions. Modifications of histones and DNA comprise the complex epigenome, and these influence chromatin structure, genome stability and gene expression, all of which are fundamental to the cel作者: Alcove 時(shí)間: 2025-3-29 10:42 作者: indices 時(shí)間: 2025-3-29 14:02
Introducing Geostatistical Methodsrafish model including ex vivo development and large clutch sizes, which enable large-scale genetic and chemical screens. Transparency of the embryo and the creation of adult zebrafish devoid of pigmentation (.) have permitted unprecedented ability to dynamically visualize cancer progression in live作者: 錯(cuò) 時(shí)間: 2025-3-29 19:04 作者: arthroplasty 時(shí)間: 2025-3-29 21:06
Introducing Geostatistical Methodse for studying development, immunology, regeneration and cancer biology. In experimental settings, tumor cell engraftment into immunologically competent recipients has greatly increased our understanding of the mechanisms that drive self-renewal, progression and metastasis in vivo. Zebrafish have qu作者: 吹牛需要藝術(shù) 時(shí)間: 2025-3-30 01:23 作者: harmony 時(shí)間: 2025-3-30 06:46 作者: conifer 時(shí)間: 2025-3-30 08:16
Group transfer polymerizations,eukemic treatment resistance and disease relapse promise to improve therapeutic strategies. The zebrafish (.) is a vertebrate organism with a conserved hematopoietic program and unique experimental strengths suiting it for the investigation of human leukemia. Recent technological advances in zebrafi作者: Guileless 時(shí)間: 2025-3-30 14:39
New Methods of Polymer Synthesisma. Both vertebrate and invertebrate model systems have been developed to study the tumor biology of both embryonal (ERMS) and alveolar (ARMS) RMS subtypes. Zebrafish RMS models have been particularly amenable for high-throughput studies to identify drug targetable pathways because of their short tu作者: 起草 時(shí)間: 2025-3-30 17:20
New Methods of Polymer Synthesisated cellular and molecular mechanisms of liver and pancreatic cancer formation and progression. In this chapter, we review the recent approaches and advances in the field to study both hepatocellular carcinomas and pancreatic cancer.作者: incision 時(shí)間: 2025-3-30 21:08 作者: 物質(zhì) 時(shí)間: 2025-3-31 03:59
New Methods of Polymer Synthesisated cellular and molecular mechanisms of liver and pancreatic cancer formation and progression. In this chapter, we review the recent approaches and advances in the field to study both hepatocellular carcinomas and pancreatic cancer.作者: effrontery 時(shí)間: 2025-3-31 09:05
Baiting for Cancer: Using the Zebrafish as a Model in Liver and Pancreatic Cancerated cellular and molecular mechanisms of liver and pancreatic cancer formation and progression. In this chapter, we review the recent approaches and advances in the field to study both hepatocellular carcinomas and pancreatic cancer.作者: separate 時(shí)間: 2025-3-31 12:07 作者: 成績(jī)上升 時(shí)間: 2025-3-31 16:02 作者: BRAND 時(shí)間: 2025-3-31 18:25 作者: 流浪者 時(shí)間: 2025-4-1 01:27
978-3-319-80860-4The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl作者: ablate 時(shí)間: 2025-4-1 05:23
Uncharted Waters: Zebrafish Cancer Models Navigate a Course for Oncogene Discoveryade. Sophisticated genetic tools have been built to generate oncogene expressing cancers and characterize multiple models of solid and blood tumors. These models have led to unique insights into mechanisms of tumor initiation and progression. New drug targets have been identified, particularly throu
