標(biāo)題: Titlebook: Cancer Therapy; Differentiation, Imm Natale D’Alessandro,Enrico Mihich,Thomas R. Tritto Conference proceedings 1993 Springer-Verlag Berlin [打印本頁] 作者: Iodine 時間: 2025-3-21 17:25
書目名稱Cancer Therapy影響因子(影響力)
書目名稱Cancer Therapy影響因子(影響力)學(xué)科排名
書目名稱Cancer Therapy網(wǎng)絡(luò)公開度
書目名稱Cancer Therapy網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Cancer Therapy被引頻次
書目名稱Cancer Therapy被引頻次學(xué)科排名
書目名稱Cancer Therapy年度引用
書目名稱Cancer Therapy年度引用學(xué)科排名
書目名稱Cancer Therapy讀者反饋
書目名稱Cancer Therapy讀者反饋學(xué)科排名
作者: 拒絕 時間: 2025-3-21 21:34 作者: 不連貫 時間: 2025-3-22 04:05 作者: hankering 時間: 2025-3-22 07:01 作者: 排斥 時間: 2025-3-22 11:38 作者: 浪費時間 時間: 2025-3-22 13:09 作者: 浪費時間 時間: 2025-3-22 20:02
Yukio Kitade,Takashi Mori,Yukihiro Akaoerol (Habenicht et al.1980; Goldstein, Brown, 1990). Mevalonate is an essential precursor of several important cellular constituents, including: cholesterol, involved in cell membrane maintenance; heme A and ubiquinone, involved in electron transport; dolychol, required for glycoprotein synthesis; a作者: 破譯密碼 時間: 2025-3-22 21:21
Colon Cancer Cell Differentiation as Related to Methotrexate and 5-Fluorouracil Resistance,normal epithelial intestinal cells, i.e. enterocytes or goblet cells. Whether these cells, which behave like normal cells as to their differentiation characteristics and functions, possess particular adaptation properties which allow them to escape the cytotoxic effect of a number of stress conditio作者: Delude 時間: 2025-3-23 02:04 作者: 辯論的終結(jié) 時間: 2025-3-23 06:05
Interferon Regulation of Differentiation and Mechanisms,globin synthesis pathway. It is postulated that IFN induces the enhancing effect on differentiation via a marked increase of heme synthesis and number of transferrin receptors which in turn leads to an enhancement of globin chain synthesis.作者: Cognizance 時間: 2025-3-23 12:51
Potential Role of Tumor Cell Antigen Modulation in Cancer Immunotherapy,cinoma cell population. Several clinical trials utilizing MAbs conjugated with radionuclides have shown preferential localization to human carcinomas (Colcher ., 1987a, b; Colcher ., 1990; Schlom ., 1989, 1991). Among the various MAbs generated, MAb B72.3 has been extensively used in clinical trials作者: Mobile 時間: 2025-3-23 17:15 作者: 逃避系列單詞 時間: 2025-3-23 18:31 作者: 紋章 時間: 2025-3-23 22:35
Natale D’Alessandro,Enrico Mihich,Thomas R. Tritto作者: 變白 時間: 2025-3-24 05:50
1010-8793 , which may support or evensubstitute chemotherapy: differentiation, immunomodulation,and inhibition of angiogenesis.Differentiation shouldnormalize neoplastic cells and makethem compatible with the host. Itsfeasibility withretinoids, interferons, chemotherapeutic and other agentsisdiscussed. Modula作者: ALTER 時間: 2025-3-24 08:42
https://doi.org/10.1007/978-1-4020-6176-9osyl cytosine, daunomycin and actinomycin D have been shown capable of inducing tumor cell maturation [1,2,4,6,8,11,13,15,16,18–30], and we have examined the mechanism by which they initiate the maturation process.作者: 等待 時間: 2025-3-24 14:28
https://doi.org/10.1007/978-1-4020-6176-9ng that the increased number of malignant cells in the bone marrow and in the blood is due to an accumulation more than to a proliferative effect. The accumulation is the consequence of a long survival of malignant cells probably due to an impairment of the cell death program related to the immaturity of the cells.作者: ANTH 時間: 2025-3-24 16:54 作者: 蘆筍 時間: 2025-3-24 21:12 作者: 我不明白 時間: 2025-3-25 02:17
ATRA Therapy in Acute Promyelocytic Leukemia a Model for Differentiation Therapy,ng that the increased number of malignant cells in the bone marrow and in the blood is due to an accumulation more than to a proliferative effect. The accumulation is the consequence of a long survival of malignant cells probably due to an impairment of the cell death program related to the immaturity of the cells.作者: 倔強不能 時間: 2025-3-25 06:07
Activation of Macrophages by Treatment of Rat Peritoneal Cells with Photofrin II and He-Ne Laser,ytes treated with PDT to macrophages increased their biological properties; (iii) cytotoxic activity of PDT-AM? varied between 31.6 and 78.6% function of the tumor target cells; (iv) the three sets of macrophages exerted cytostatic effects upon human and mouse leukemia cells.作者: Acetaldehyde 時間: 2025-3-25 07:51
Hemin is Transported in Human Leukemia K562 Cells and Interacts with DNA Sequences,uroblastoma (Ishii et al, 1978), erythroleukemia (MEL, K562) cells (Ross et al, 1976; Rutherford et al, 1979a; Tsiftsoglou and Robinson, 1985; Tsiftsoglou et al, 1991) as well as normal hematopoietic cells like CFU-E, CFU-GM and BFU-E (Monette et al, 1982) by interacting with cellular components at various levels (Sassa et al, 1988).作者: 清洗 時間: 2025-3-25 15:08
,CNS and Cardiovascular Effects of TNF-α,l injection of recombinant TNF-α has profound cardiovascular and neurological effects in addition to its pyrogenic and metabolic activity. Understanding and elucidating the mechanisms underlying cardiovascular and CNS toxicity should enable the design of molecules to oppose this toxicity without interfering with the immune reactions.作者: 橡子 時間: 2025-3-25 18:02 作者: Excitotoxin 時間: 2025-3-25 23:53
Conference proceedings 1993y support or evensubstitute chemotherapy: differentiation, immunomodulation,and inhibition of angiogenesis.Differentiation shouldnormalize neoplastic cells and makethem compatible with the host. Itsfeasibility withretinoids, interferons, chemotherapeutic and other agentsisdiscussed. Modulation by bi作者: 暖昧關(guān)系 時間: 2025-3-26 00:27 作者: 光明正大 時間: 2025-3-26 04:32
New Horizons of Quantum Chemistryl injection of recombinant TNF-α has profound cardiovascular and neurological effects in addition to its pyrogenic and metabolic activity. Understanding and elucidating the mechanisms underlying cardiovascular and CNS toxicity should enable the design of molecules to oppose this toxicity without interfering with the immune reactions.作者: 小蟲 時間: 2025-3-26 09:52
Konstantia Kapetangianni,T. Daniel Seelyction may be achieved through optimization of regimens, particularly of combination chemotherapy. Likewise much work is being done to overcome and/or prevent resistance, taking advantage of recently obtained information on some of the mechanisms involved.作者: Stricture 時間: 2025-3-26 12:52 作者: Pandemic 時間: 2025-3-26 18:13 作者: aplomb 時間: 2025-3-26 23:20 作者: 異端邪說下 時間: 2025-3-27 02:05
Differential Effects of Low Doses Of Structurally Different Anthracyclines on Immunoglobulin ProducDOX induces the blockade of cell proliferation through an accumulation of the cells in the G2 + M phase of the cell cycle as well as a strong increase of the Immunoglobulin (Ig) production (Teillaud et al., 1989), suggesting a terminal differentiation in “plasma-like” cells.作者: 培養(yǎng) 時間: 2025-3-27 07:34
Chemical Xenogenization of Experimental Tumors by Antineoplastic Drugs,posure to the antitumor agent dacarbazine, would become increasingly immunogenic, eventually acquiring a degree of foreignness capable of resulting in tumor cell rejection by the histocompatible host.作者: ABOUT 時間: 2025-3-27 12:57
Colon Cancer Cell Differentiation as Related to Methotrexate and 5-Fluorouracil Resistance,herapy. Although it has been assumed that drug resistance could be associated with some particular cell populations, these have not been characterized yet. It is only in recent years that progress in the field of intestinal cell biology, based on the development of cultured cell lines and availabili作者: 鈍劍 時間: 2025-3-27 15:11
The Control of Cell Multiplication and Differentiation in Human Myelomonocytic Cells,her susceptible or resistant to such a differentiation induced by phorbol 12-myristate 13- acetate (PMA). Unlike the cells from susceptible cell lines, the PMA-resistant variants did not express the genes that code for the protein kinase C (PKC) β isozyme and a “δ-like” PKC. The resistant cells also作者: AVANT 時間: 2025-3-27 21:30
Signal Transduction Mechanisms as a Target for Cancer Chemotherapy,devoted to understanding its mechanism of action. As summarized in Table 1, several proposals have been offered to explain the anticancer activity of adriamycin and other members of the anthracycline family.作者: –DOX 時間: 2025-3-27 22:37
Therapeutic Approaches for Colon Cancer Based on Transcriptional Regulation of Specific Growth Fact a consequence, this tumor has been the subject of extensive investigations seeking alternative or perhaps supplemental therapies based on biochemical, biological or immunological properties of colon cancer cells which are not shared by normal cells.作者: Freeze 時間: 2025-3-28 03:03 作者: CHIDE 時間: 2025-3-28 07:53 作者: Barter 時間: 2025-3-28 14:18 作者: 圍巾 時間: 2025-3-28 17:19 作者: 提名的名單 時間: 2025-3-28 20:41
Immunomodulation by Anticancer Drugs in Therapeutics,rge proportion of patients with the most common so-called solid tumors can be provided curative treatments. The limitations of chemotherapy are essentially related to the insufficient selectivity of antitumor activity of the drugs available and to the phenomenon of resistance. Intensive efforts are 作者: allergy 時間: 2025-3-29 01:46
Differential Effects of Low Doses Of Structurally Different Anthracyclines on Immunoglobulin Producuction of molecules that are usually synthesized by terminally-differentiated cells. For instance, anti-neoplastic drugs such as Ara-C or doxorubicin (DOX) promote the irreversible induction of hemoglobin (Hb) synthesis in human erythroleukemia K562 cells with a concomitant loss of proliferative cap作者: Anal-Canal 時間: 2025-3-29 04:12 作者: Pepsin 時間: 2025-3-29 10:38
Reversal of Drug Resistance: Synergistic Anti-Tumor Cytotoxic Activity by Combination Treatment witre is relapse with the development of metastases and highly resistant tumor cells. A major challenge remains in the development of new therapeutic modalities that can treat widespread metastases and drug resistant tumors.作者: Ardent 時間: 2025-3-29 15:03 作者: ADOPT 時間: 2025-3-29 18:31
Effects of Tumor Necrosis Factor-Alpha on Growth and Doxorubicin Sensitivity of Multidrug Resistant effect as well as the possibility to favourably modulate tumor sensitivity to antineoplastic drugs (Alexander et al., 1987; Kikuchi et al., 1992; Wadler and Schwartz, 1990). However, information on their activity on chemoresistant tumors is still scanty (Billi et al., 1991; Bonavida et al., 1989; D作者: 爭吵加 時間: 2025-3-29 22:42 作者: 大約冬季 時間: 2025-3-30 03:37
Synergic Interaction between Simvastatin and Antineoplastic Drugs on Glioma Cell Growth,d several non sterol products in animal cells (Goldstein, Brown, 1990). Inhibition of this enzyme triggers regulatory response that lowers the concentrations of low density lipoproteins (LDL) in blood. A major relationship exists between the cell growth processes and the mevalonate biosynthetic path作者: Congruous 時間: 2025-3-30 05:53
,CNS and Cardiovascular Effects of TNF-α,ical trials turned out to be impraticable because of severe systemic side-effects (Chouaib et al., 1992). The cardiovascular system and Central Nervous System (CNS) represent the main targets of Tumor Necrosis Factor (TNF-α) toxicity. Experimental studies have confirmed that systemic or intracerebra作者: Misgiving 時間: 2025-3-30 11:57
Nato ASI Subseries H:http://image.papertrans.cn/c/image/221215.jpg作者: Confidential 時間: 2025-3-30 13:27 作者: FIN 時間: 2025-3-30 17:53
https://doi.org/10.1007/978-94-010-0864-8With the discovery of the lymphokine-activated killer (LAK) cell phenomenon, a new type of tumor-killing cells that are easily obtained and expanded in the laboratory and show a broad reactivity against a variety of different tumors became available for cancer therapy (Grimm .., 1982).作者: 擁護(hù) 時間: 2025-3-30 22:22 作者: Intact 時間: 2025-3-31 04:45
Immunomodulation in Cancer Patients Treated with Interleukin-2. Induction of Non-Specific and SpeciWith the discovery of the lymphokine-activated killer (LAK) cell phenomenon, a new type of tumor-killing cells that are easily obtained and expanded in the laboratory and show a broad reactivity against a variety of different tumors became available for cancer therapy (Grimm .., 1982).作者: 巨碩 時間: 2025-3-31 05:27 作者: 反對 時間: 2025-3-31 12:23 作者: 不能平靜 時間: 2025-3-31 13:44
New Horizons in Workplace Well-Beingdevoted to understanding its mechanism of action. As summarized in Table 1, several proposals have been offered to explain the anticancer activity of adriamycin and other members of the anthracycline family.作者: 沒花的是打擾 時間: 2025-3-31 20:13
Lie Methods in the Theory of pro-, Groups, a consequence, this tumor has been the subject of extensive investigations seeking alternative or perhaps supplemental therapies based on biochemical, biological or immunological properties of colon cancer cells which are not shared by normal cells.作者: colony 時間: 2025-3-31 22:06 作者: FILTH 時間: 2025-4-1 05:05
https://doi.org/10.1007/978-1-4020-6176-9ion accompanied by cessation of growth constitutes a potentially promising approach for therapy. Numerous DNA-specific antitumor agents such as arabinosyl cytosine, daunomycin and actinomycin D have been shown capable of inducing tumor cell maturation [1,2,4,6,8,11,13,15,16,18–30], and we have exami作者: 調(diào)色板 時間: 2025-4-1 06:16 作者: 清楚說話 時間: 2025-4-1 13:30 作者: Asperity 時間: 2025-4-1 16:01
Konstantia Kapetangianni,T. Daniel Seelyrge proportion of patients with the most common so-called solid tumors can be provided curative treatments. The limitations of chemotherapy are essentially related to the insufficient selectivity of antitumor activity of the drugs available and to the phenomenon of resistance. Intensive efforts are 作者: 不知疲倦 時間: 2025-4-1 18:46 作者: FLUSH 時間: 2025-4-2 01:11
