標(biāo)題: Titlebook: Cancer Systems Biology, Bioinformatics and Medicine; Research and Clinica Alfredo Cesario,Frederick Marcus Book 2011 The Editor(s) (if appl [打印本頁(yè)] 作者: Optician 時(shí)間: 2025-3-21 17:05
書(shū)目名稱Cancer Systems Biology, Bioinformatics and Medicine影響因子(影響力)
書(shū)目名稱Cancer Systems Biology, Bioinformatics and Medicine影響因子(影響力)學(xué)科排名
書(shū)目名稱Cancer Systems Biology, Bioinformatics and Medicine網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Cancer Systems Biology, Bioinformatics and Medicine網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Cancer Systems Biology, Bioinformatics and Medicine被引頻次
書(shū)目名稱Cancer Systems Biology, Bioinformatics and Medicine被引頻次學(xué)科排名
書(shū)目名稱Cancer Systems Biology, Bioinformatics and Medicine年度引用
書(shū)目名稱Cancer Systems Biology, Bioinformatics and Medicine年度引用學(xué)科排名
書(shū)目名稱Cancer Systems Biology, Bioinformatics and Medicine讀者反饋
書(shū)目名稱Cancer Systems Biology, Bioinformatics and Medicine讀者反饋學(xué)科排名
作者: Intractable 時(shí)間: 2025-3-21 21:50
Cancer: Clinical Background and Key Challengesystems approaches to the pathology and treatment of cancer. In particular, it addresses diagnosis and therapy by interconnecting various aspects of cancer at both the molecular and clinical level, and contrasts the unifying features of malignancies with the daunting diversity of cancer types, stages作者: obstruct 時(shí)間: 2025-3-22 00:50
Global Molecular and Cellular Measurement Technologiesencing field where capacity and throughput have increased by several orders of magnitude. This has been a major factor in systems biology research, which thrives on technologies facilitating efficient and relatively economical genome-wide readout on DNA, mRNA, protein, and metabolome level. With dat作者: 拖債 時(shí)間: 2025-3-22 08:26 作者: APEX 時(shí)間: 2025-3-22 09:41 作者: Enliven 時(shí)間: 2025-3-22 12:53 作者: Enliven 時(shí)間: 2025-3-22 19:38 作者: 新奇 時(shí)間: 2025-3-22 22:50
Computational Tools for Systems Biologyiew of the available tools and methods. The reader is familiarised with the development of standards in computational systems biology regarding description and annotation of models, methods, and data standards which enable communication between different groups working in the same field and permit a作者: hardheaded 時(shí)間: 2025-3-23 02:57
The Hallmarks of Cancer Revisited Through Systems Biology and Network Modellingnvestigations, new systems-based approaches have provided a wide range of improved investigative methods. These approaches integrate various global data types into mathematical and computational models of molecular and cellular pathways and networks that become dysregulated in cancer, since the mode作者: 認(rèn)為 時(shí)間: 2025-3-23 09:37
Systems Biology Analysis of Cell Death Pathways in Cancer: How Collaborative and Interdisciplinary Rlation in this genetically-regulated process plays an important role in the pathophysiology of different disorders. Excessive cell death is pathogenic when it concerns post-mitotic cells and results in various diseases, such as infarction, stroke or neurodegenerative disorders. Insufficient cell dea作者: Emmenagogue 時(shí)間: 2025-3-23 13:40 作者: 幻想 時(shí)間: 2025-3-23 14:48
System Dynamics at the Physiological and Tumour Level spatial heterogeneity. This variability, while critical to the ability of cancers to adapt to a wide range of environmental perturbations including therapy, tends to be lost in molecular-level data which is typically an ‘a(chǎn)verage’ value for large numbers of heterogeneous tumour cells obtained at a s作者: 非秘密 時(shí)間: 2025-3-23 19:33 作者: FRAX-tool 時(shí)間: 2025-3-24 01:19 作者: opprobrious 時(shí)間: 2025-3-24 04:16
Circadian Rhythms and Cancer Chronotherapeuticscellular clocks are coordinated by a hypothalamic pacemaker, the suprachiasmatic nuclei, which generate or control circadian physiology. The CTS down-regulates malignant growth in experimental models and in cancer patients. It also generates large and predictable 24-h changes in toxicity and efficac作者: 恃強(qiáng)凌弱 時(shí)間: 2025-3-24 06:44
https://doi.org/10.1057/9780230591509f knowledge and decisions; organize information in more accessible and applicable ways; extend understanding of complicated biological interactions; and provide numerical test beds for planning and implementing biomarker and drug development and treatment strategies.作者: 有害處 時(shí)間: 2025-3-24 10:40
https://doi.org/10.1007/978-1-349-26622-7marker effective discovery and prioritisation..Finally, we emphasize the need for large-scale harmonization, standardization and integration of multi-level data to ensure that the potential offered by the current unprecedented availability of data and information is fully exploited, so as to develop validated and useful biomarkers.作者: 天氣 時(shí)間: 2025-3-24 16:32
Diagnostic and Prognostic Cancer Biomarkers: From Traditional to Systems Approachesmarker effective discovery and prioritisation..Finally, we emphasize the need for large-scale harmonization, standardization and integration of multi-level data to ensure that the potential offered by the current unprecedented availability of data and information is fully exploited, so as to develop validated and useful biomarkers.作者: Annotate 時(shí)間: 2025-3-24 22:34 作者: 連鎖,連串 時(shí)間: 2025-3-24 23:34
Introduction to Systems Approaches to Cancerf knowledge and decisions; organize information in more accessible and applicable ways; extend understanding of complicated biological interactions; and provide numerical test beds for planning and implementing biomarker and drug development and treatment strategies.作者: Diatribe 時(shí)間: 2025-3-25 04:03 作者: Carcinogen 時(shí)間: 2025-3-25 09:00
Beginning and End of Biological Lifeble biomedical knowledge, and specifically to generate quantitative data and analyse the system using theoretical and computational tools, are compared and discussed, but new avenues are also suggested.作者: abysmal 時(shí)間: 2025-3-25 14:14 作者: ITCH 時(shí)間: 2025-3-25 16:07
New Historicism and Cultural Materialismgether is capable of designing optimal drug schedules and combinations, is often the focus at the industrial level. This chapter describes a typical modelling approach, and shows how it is being used to aid the drug development process.作者: 消息靈通 時(shí)間: 2025-3-25 22:30 作者: 悶熱 時(shí)間: 2025-3-26 02:00
Mathematical Tools in Cancer Signalling Systems Biologyble biomedical knowledge, and specifically to generate quantitative data and analyse the system using theoretical and computational tools, are compared and discussed, but new avenues are also suggested.作者: 不安 時(shí)間: 2025-3-26 04:27
Computational Tools for Systems Biologytion, and storage, as used in systems biology and cancer research. Web resources and strategies to combine different tools are introduced. We present examples of the successful application of tools and strategies in modelling and model-based prediction in disease-related areas of molecular and cellular biology.作者: Parallel 時(shí)間: 2025-3-26 10:48 作者: 盡責(zé) 時(shí)間: 2025-3-26 16:00 作者: BLA 時(shí)間: 2025-3-26 19:38 作者: Canyon 時(shí)間: 2025-3-26 22:48 作者: 稀釋前 時(shí)間: 2025-3-27 04:14 作者: BUMP 時(shí)間: 2025-3-27 09:03
James E. Wilberger Jr.,C. Don Keyesdressed via multiscale modelling. Enhanced understanding of the initial hallmarks of cancer, extended to the control of metabolism and stress, is opening novel avenues for cancer diagnosis and treatment. It is fully expected that further progress will take place through iterative cycles of experimen作者: 流逝 時(shí)間: 2025-3-27 10:49 作者: 完全 時(shí)間: 2025-3-27 13:41
New Historicism and Cultural Materialism step will be to model the gene array-derived biological motifs as a function of a manageable number of signalling pathways or signalling network constellations. The advantages of translating biological motifs into pathway signatures are the possibility of identification of pathologic pathways in in作者: Nonthreatening 時(shí)間: 2025-3-27 20:42 作者: 想象 時(shí)間: 2025-3-28 00:35
https://doi.org/10.1007/978-0-387-89518-5lity in circadian entrainment, cell cycle length, and phase durations, which determine the success of cancer chronotherapeutics. Stochastic and deterministic models further confirm the poor therapeutic value of constant-rate infusion or wrongly-timed chronomodulated infusion. The integration of the 作者: Tortuous 時(shí)間: 2025-3-28 04:39 作者: 熒光 時(shí)間: 2025-3-28 08:05 作者: Phagocytes 時(shí)間: 2025-3-28 12:04
Cancer: Clinical Background and Key Challengesofiling. The application of systems approaches to cancer-related clinical practice and research is discussed. The necessity is demonstrated for signalling pathways analysis to be fully integrated into grading and clinical staging of cancers, as well as into the process of discovering novel targets a作者: intuition 時(shí)間: 2025-3-28 17:00
Global Molecular and Cellular Measurement Technologies patterns. Sequencing technologies are developing rapidly, as are preparatory enrichment techniques, which include the amplification of sample signal or target enrichment to reduce sample complexity. Proteomics and functional assays have also been much advanced as a result of technological progress 作者: 上下連貫 時(shí)間: 2025-3-28 21:12
Expression and Genetic Variation Databases for Cancer Researchdata is stored in large repositories, and new services have been developed that take advantage of the increasing number and diversity of stored experiments. By associating data with biological information and integrative analysis, it can be transformed from high dimensionality to a summary level tha作者: Figate 時(shí)間: 2025-3-29 01:06 作者: infinite 時(shí)間: 2025-3-29 05:50
Systems Biology Analysis of Cell Death Pathways in Cancer: How Collaborative and Interdisciplinary Rhways and the various feedback mechanisms indicate that a systems biology approach with mathematical modelling is needed to fully describe and understand the processes involved. The models based on these studies are crucial to effective drug development, drug testing, and optimal choice of combinati作者: 外形 時(shí)間: 2025-3-29 11:04
Systems Biology, Bioinformatics and Medicine Approaches to Cancer Progression Outcomes step will be to model the gene array-derived biological motifs as a function of a manageable number of signalling pathways or signalling network constellations. The advantages of translating biological motifs into pathway signatures are the possibility of identification of pathologic pathways in in作者: 改變 時(shí)間: 2025-3-29 11:27 作者: 改正 時(shí)間: 2025-3-29 17:40
Circadian Rhythms and Cancer Chronotherapeuticslity in circadian entrainment, cell cycle length, and phase durations, which determine the success of cancer chronotherapeutics. Stochastic and deterministic models further confirm the poor therapeutic value of constant-rate infusion or wrongly-timed chronomodulated infusion. The integration of the 作者: 變量 時(shí)間: 2025-3-29 20:23 作者: 最有利 時(shí)間: 2025-3-30 01:10
Cancer Systems Biology, Bioinformatics and Medicine978-94-007-1567-7作者: Cosmopolitan 時(shí)間: 2025-3-30 06:23 作者: Left-Atrium 時(shí)間: 2025-3-30 09:10 作者: 公社 時(shí)間: 2025-3-30 15:44 作者: Albinism 時(shí)間: 2025-3-30 16:34
https://doi.org/10.1007/978-94-007-1567-7Bioinformatics; Cancer; Systems Biology; Systems Medicine作者: abject 時(shí)間: 2025-3-30 21:22 作者: 背帶 時(shí)間: 2025-3-31 04:07
https://doi.org/10.1057/9780230591509bility. These could be eased by integrated systems approaches to biology, bioinformatics and medicine. Such approaches have already proved successful in optimizing cancer-related research and clinical applications, building upon existing practice. In particular, they enhance the quantitative basis o作者: 脊椎動(dòng)物 時(shí)間: 2025-3-31 06:49
Karen S. Sahin,R. Steven Turnerystems approaches to the pathology and treatment of cancer. In particular, it addresses diagnosis and therapy by interconnecting various aspects of cancer at both the molecular and clinical level, and contrasts the unifying features of malignancies with the daunting diversity of cancer types, stages作者: 蝕刻 時(shí)間: 2025-3-31 09:39