標(biāo)題: Titlebook: Cancer Microenvironment and Therapeutic Implications; Tumor Pathophysiolog Gianfranco Baronzio,Gianfranco Fiorentini,Christop Book 2009 Spr [打印本頁] 作者: 不同 時(shí)間: 2025-3-21 19:44
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書目名稱Cancer Microenvironment and Therapeutic Implications讀者反饋學(xué)科排名
作者: 畸形 時(shí)間: 2025-3-21 20:44 作者: cloture 時(shí)間: 2025-3-22 03:46
entists merging experiences at the lab bench with the fight .In the post-genomic era, cancer is a genetic disease. However, cancer genotype does not always equal cancer phenotype. Cancers with the same genetic abnormalities don’t always behave the same. Understanding and eradicating cancers will req作者: adulterant 時(shí)間: 2025-3-22 08:08
Cancer, Stem Cells and the Neoplastic Niche the proper cancer target. Designing novel therapeutics for cancer eradication will require understanding specific pathways involved in cancer initiating cell self-renewal, differentiation and homing. Furthermore, targeting the distinctions of the cancer initiating cell microenvironment may be key to effective cancer therapies.作者: anagen 時(shí)間: 2025-3-22 12:12
Significance of the Tumour Microenvironment in Radiotherapyly radiosensitising hypoxic cells, or killing them with specific cytotoxins. More recent approaches have concentrated on the tumour vascular supply itself. Many of these hypoxia targeted therapies have shown benefit in clinical trials, but while additional testing is ongoing for some of them, newer agents are continually being developed.作者: CLOT 時(shí)間: 2025-3-22 13:54 作者: CLOT 時(shí)間: 2025-3-22 21:03 作者: neuron 時(shí)間: 2025-3-22 22:53 作者: fatty-streak 時(shí)間: 2025-3-23 01:23 作者: 打谷工具 時(shí)間: 2025-3-23 06:40
Targeting Tumour Vascularization from Bench to Bedside: Suggestions for Combination with Hyperthermiis chapter we summarize the state of the art regarding the combination between drugs that targeting tumour vasculature and hyperthermia, furthermore the pre-clinical rationale for future clinical trials is suggested.作者: obligation 時(shí)間: 2025-3-23 13:31 作者: 延期 時(shí)間: 2025-3-23 17:46 作者: 他去就結(jié)束 時(shí)間: 2025-3-23 18:44
Book 2009abnormalities don’t always behave the same. Understanding and eradicating cancers will require an appreciation for cancer’s ecology...This book is the first to comprehensively explore and critically appraise cancer microenvironments and host interactions with an eye towards exploiting our understand作者: Overthrow 時(shí)間: 2025-3-24 00:09
Pierre Dillenbourg,Patrick Mendelsohnrix and stromal elements. These microenvironmental changes usually serve as a selection advantage for the malignant growths, therefore, recently stroma-targeted novel therapeutic strategies are being investigated.作者: hegemony 時(shí)間: 2025-3-24 02:55
https://doi.org/10.1007/978-3-642-77681-6ficult for blood-borne drugs to reach the tumor’s inner core. In this review, we describe tumor physiology resulting in barriers and forces that govern drug distribution inside tumor regions. Furthermore, we present strategies to overcome these impediments.作者: 把…比做 時(shí)間: 2025-3-24 07:14
Tumor Microenvironment: Aspects of Stromal-Parenchymal Interactionrix and stromal elements. These microenvironmental changes usually serve as a selection advantage for the malignant growths, therefore, recently stroma-targeted novel therapeutic strategies are being investigated.作者: connoisseur 時(shí)間: 2025-3-24 13:46
Barriers to Drug Delivery in Cancer: Clinical Implicationsficult for blood-borne drugs to reach the tumor’s inner core. In this review, we describe tumor physiology resulting in barriers and forces that govern drug distribution inside tumor regions. Furthermore, we present strategies to overcome these impediments.作者: Optometrist 時(shí)間: 2025-3-24 18:05
Cancer Microenvironment and Therapeutic ImplicationsTumor Pathophysiolog作者: arrhythmic 時(shí)間: 2025-3-24 21:28
Cancer Microenvironment and Therapeutic Implications978-1-4020-9576-4作者: 語言學(xué) 時(shí)間: 2025-3-25 01:19
gists, immunologists, stem cell researchers, oncology and hematology fellows (trainees), oncology educators (graduate and undergraduate levels), and course book for graduate students and undergraduate students..978-90-481-8160-5978-1-4020-9576-4作者: Pseudoephedrine 時(shí)間: 2025-3-25 05:16
What’s in an ITS? A Functional Decompositionsemination are enhanced while the tumor can generate a matrix supporting neoangiogenesis. In the unique tumor microenvironment, both endothelial cells and tumor cells express a wide variety of factors, including procoagulants, cell adhesion molecules, vasomotor substances and cell survival signals. 作者: faculty 時(shí)間: 2025-3-25 08:58
https://doi.org/10.1007/978-1-4612-3472-2 Furthermore, the tumor microcirculation creates barriers that hinder drug delivery to the tumor mass. Systemic chemotherapy often reduces tumor burden but rarely is effective in completely eliminating the tumor. This has created the need for the development of more effective cancer therapies. To th作者: objection 時(shí)間: 2025-3-25 13:30
Significance of Tumor Microenvironment on the Genesis of: Interstitial Fluid, Angiogenesis, Haemostasemination are enhanced while the tumor can generate a matrix supporting neoangiogenesis. In the unique tumor microenvironment, both endothelial cells and tumor cells express a wide variety of factors, including procoagulants, cell adhesion molecules, vasomotor substances and cell survival signals. 作者: Deduct 時(shí)間: 2025-3-25 19:53
Effects of Tumor Microenvironment on Hyperthermia, Photodynamic and Nanotherapy Furthermore, the tumor microcirculation creates barriers that hinder drug delivery to the tumor mass. Systemic chemotherapy often reduces tumor burden but rarely is effective in completely eliminating the tumor. This has created the need for the development of more effective cancer therapies. To th作者: 無法取消 時(shí)間: 2025-3-25 21:40 作者: BULLY 時(shí)間: 2025-3-26 03:54
R. López de Mántaras,C. Sierra,J. Agustíing the differences between normal and neoplastic cells at biomolecular properties. The physiology of tumours is substantially different from that of normal tissues from which we have a unique and selective target for cancer treatment.作者: Parley 時(shí)間: 2025-3-26 05:59
New Directions for Medical Educationssure. New multi-target tyrosine kinase inhibitors are new therapeutically options in solid tumours. They share the capacity of modulate the hypoxia inducible factor (HIF)-VEGF-VEGF receptor sequence that plays a predominant role in the development of solid tumours.作者: 組成 時(shí)間: 2025-3-26 11:08
Inflammation and Carcinogenesis: A Change in the Metabolic Process foreign body or chemicals. In every case, there is a protein leak from the damaged capillaries. This results in increased oncotic pressure which is in turn responsible for the methylation of the PP2A phosphatase. The activation of PP2A results in the translocation of NF κB and the activation of several metabolic pathways.作者: 激勵(lì) 時(shí)間: 2025-3-26 15:45
Hypoxia, Hyperthermia, Chemotherapy: Interactions and Opportunitiesing the differences between normal and neoplastic cells at biomolecular properties. The physiology of tumours is substantially different from that of normal tissues from which we have a unique and selective target for cancer treatment.作者: occult 時(shí)間: 2025-3-26 18:53
Effects of Molecularly Targeting Hypoxia in Oncologyssure. New multi-target tyrosine kinase inhibitors are new therapeutically options in solid tumours. They share the capacity of modulate the hypoxia inducible factor (HIF)-VEGF-VEGF receptor sequence that plays a predominant role in the development of solid tumours.作者: Decibel 時(shí)間: 2025-3-26 23:50 作者: Adrenal-Glands 時(shí)間: 2025-3-27 02:12
978-90-481-8160-5Springer Science+Business Media B.V. 2009作者: 來自于 時(shí)間: 2025-3-27 08:53
R. López de Mántaras,C. Sierra,J. Agustí foreign body or chemicals. In every case, there is a protein leak from the damaged capillaries. This results in increased oncotic pressure which is in turn responsible for the methylation of the PP2A phosphatase. The activation of PP2A results in the translocation of NF κB and the activation of sev作者: Ledger 時(shí)間: 2025-3-27 13:02 作者: 粘連 時(shí)間: 2025-3-27 14:33 作者: 人工制品 時(shí)間: 2025-3-27 18:48
A Structure for Epistemic Stateswever, not only are cancers heterogeneous, but also small subsets are endowed with the ability to initiate cancer formation and metastasis. The resistance of cancer initiating cells to current therapies may explain high relapse rates. Our inability to eradicate cancer may be due to misrecognition of作者: Brain-Imaging 時(shí)間: 2025-3-27 23:33
https://doi.org/10.1007/978-3-642-77681-6reach target tissue at adequate concentration to perform its therapeutic effect. As reported by several authors, conventional cancer treatments do not achieve this aim, resulting in suboptimal activity and inability to eradicate tumor tissue. The reasons for this failure are multiple and partially d作者: Disk199 時(shí)間: 2025-3-28 05:57 作者: GRAZE 時(shí)間: 2025-3-28 07:12
New Directions for Medical Educationssure. New multi-target tyrosine kinase inhibitors are new therapeutically options in solid tumours. They share the capacity of modulate the hypoxia inducible factor (HIF)-VEGF-VEGF receptor sequence that plays a predominant role in the development of solid tumours.作者: tackle 時(shí)間: 2025-3-28 10:39
Needed: A New Way to Train Doctorsmour neo-vasculature result in development of oxygen deprived areas. Hypoxic cells existing in this environment are resistant to radiation therapy. Numerous approaches have been developed to deal with this hypoxia-induced radioresistance. These include increasing oxygen delivery to tumours, chemical作者: 贊成你 時(shí)間: 2025-3-28 15:17
A Medical School for the Futuree progression of the disease can be interpreted as failure of the antitumor immune response. Recent studies indicate host immune response cooperates with cancer cells to promote their growth and dissemination through the production of several growth factors, cytokines, angiogenic factors, free radic作者: 該得 時(shí)間: 2025-3-28 22:46
https://doi.org/10.1007/978-1-4612-3472-2rced to survive in a hostile environment in contact with cancer cells. Resident and recruited fibroblasts, and a complex infiltrate of neutrophils, macrophages, lymphocytes and mast cells work in concert with neoplastic cells to create a new, distinctive microenvironment that allows for the generati作者: 刻苦讀書 時(shí)間: 2025-3-29 02:12
Dan E. Benor,Stevan E. Hobfoll,Moshe Prywesgenic inhibitors are the stimuli that induce new blood vessel formation from a pre-existing vascular bed. On the other hand tumour vasculature is a major important factor influencing the therapeutic application of hyperthermia used as anticancer therapy. Both endothelial cells and microvessels can b作者: Keratectomy 時(shí)間: 2025-3-29 05:30 作者: fulmination 時(shí)間: 2025-3-29 07:34
Gianfranco Baronzio,Gianfranco Fiorentini,ChristopA bird’s-eye view of cancer biology.A critical appraisal of cancer’s context in addition to its substance.Written by a team of physician-scientists merging experiences at the lab bench with the fight 作者: 隱藏 時(shí)間: 2025-3-29 14:01 作者: 斥責(zé) 時(shí)間: 2025-3-29 17:50 作者: synovial-joint 時(shí)間: 2025-3-29 20:25 作者: 創(chuàng)造性 時(shí)間: 2025-3-30 02:09
Significance of Tumor Microenvironment on the Genesis of: Interstitial Fluid, Angiogenesis, Haemostanefficient, poorly organized and cannot keep up with the pace of the tumor proliferation. This creates undernourished and hypoxic regions in a new environment, with neo-vasculature having a perturbed structure and function. Two abnormalities are peculiarly important. The first is an excessive leakin作者: 不怕任性 時(shí)間: 2025-3-30 06:19 作者: 我不明白 時(shí)間: 2025-3-30 11:03
Barriers to Drug Delivery in Cancer: Clinical Implicationsreach target tissue at adequate concentration to perform its therapeutic effect. As reported by several authors, conventional cancer treatments do not achieve this aim, resulting in suboptimal activity and inability to eradicate tumor tissue. The reasons for this failure are multiple and partially d
