標(biāo)題: Titlebook: Cancer Metabolomics; Methods and Applicat Shen Hu Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spr [打印本頁(yè)] 作者: intern 時(shí)間: 2025-3-21 17:01
書(shū)目名稱(chēng)Cancer Metabolomics影響因子(影響力)
作者: 啤酒 時(shí)間: 2025-3-21 22:45 作者: 痛苦一生 時(shí)間: 2025-3-22 03:06
Capillary Electrophoresis-Mass Spectrometry for Cancer Metabolomics,d when combining CE with MS, especially the interface between CE and MS and the selection of a proper separation methodology, sample pretreatment, and capillary coatings. We will discuss these aspects of CE-MS and detail representative applications for cancer metabolomic analysis.作者: Chronological 時(shí)間: 2025-3-22 06:30 作者: 不出名 時(shí)間: 2025-3-22 10:23 作者: Foment 時(shí)間: 2025-3-22 13:00
https://doi.org/10.1007/978-3-319-95756-2, especially in absolute quantification. As cancer research deepens at the level of quantitative biology and metabolomics, the demand for lipidomics approaches such as shotgun lipidomics is becoming greater. In this chapter, the principles, approaches, and some applications of shotgun lipidomics for cancer research are overviewed.作者: Foment 時(shí)間: 2025-3-22 17:14 作者: JECT 時(shí)間: 2025-3-22 22:40
Workers’ Management and the Market reveal the metabolic reprogramming mechanisms underlying head and neck cancer cell proliferation, invasion, and metastasis and may be used to identify metabolite biomarkers for clinical applications of the disease. In this chapter, we briefly review recent metabolomic applications in head and neck cancer.作者: 新鮮 時(shí)間: 2025-3-23 04:33 作者: 后天習(xí)得 時(shí)間: 2025-3-23 08:12 作者: Astigmatism 時(shí)間: 2025-3-23 10:13
Metabolomics of Oral/Head and Neck Cancer, reveal the metabolic reprogramming mechanisms underlying head and neck cancer cell proliferation, invasion, and metastasis and may be used to identify metabolite biomarkers for clinical applications of the disease. In this chapter, we briefly review recent metabolomic applications in head and neck cancer.作者: orthopedist 時(shí)間: 2025-3-23 14:00 作者: 諄諄教誨 時(shí)間: 2025-3-23 18:01
Deli Wang,Lu Cui,Lanju Zhang,Bo Yangresolution, and the applications towards metabolomic scale imaging. Finally, we discuss new computational tools to aid in metabolite identification, future perspective, and the overall direction that the field of single-cell metabolomics directly on tissue may take in the years to come.作者: Rinne-Test 時(shí)間: 2025-3-23 23:40 作者: 翻動(dòng) 時(shí)間: 2025-3-24 06:17 作者: perimenopause 時(shí)間: 2025-3-24 10:28 作者: pester 時(shí)間: 2025-3-24 10:55
Single-Cell Metabolomics by Mass Spectrometry Imaging,resolution, and the applications towards metabolomic scale imaging. Finally, we discuss new computational tools to aid in metabolite identification, future perspective, and the overall direction that the field of single-cell metabolomics directly on tissue may take in the years to come.作者: 使熄滅 時(shí)間: 2025-3-24 14:50 作者: GROUP 時(shí)間: 2025-3-24 21:56 作者: 難解 時(shí)間: 2025-3-25 00:13 作者: Anal-Canal 時(shí)間: 2025-3-25 04:42 作者: 黑豹 時(shí)間: 2025-3-25 09:19
Carmela E. Quintos,Peter C. B. Phillipsecent studies have demonstrated that IC-MS is a powerful technique with exquisite detection sensitivity, high reproducibility, and quantitative capability for metabolomic analysis. In this chapter, we provide a brief overview of IC principles and IC-MS for metabolomic analysis.作者: Proponent 時(shí)間: 2025-3-25 12:20
Shada Abuhattum,Amit Gefen,Daphne Weihsd when combining CE with MS, especially the interface between CE and MS and the selection of a proper separation methodology, sample pretreatment, and capillary coatings. We will discuss these aspects of CE-MS and detail representative applications for cancer metabolomic analysis.作者: Psychogenic 時(shí)間: 2025-3-25 16:12 作者: Glucocorticoids 時(shí)間: 2025-3-25 22:24
https://doi.org/10.1007/978-94-010-0834-1tope labeling (CIL) liquid chromatography mass spectrometry (LC-MS) offers an alternative means of increasing metabolomic coverage while maintaining high quantification precision and accuracy. This chapter describes the CIL LC-MS method and its key features for metabolomic analysis.作者: 無(wú)力更進(jìn) 時(shí)間: 2025-3-26 00:31 作者: 護(hù)身符 時(shí)間: 2025-3-26 05:30 作者: cylinder 時(shí)間: 2025-3-26 11:37
Xiaochun Wang,Xiali Wang,Mitch Wilkes to investigate cancer metabolism and identify biomarker and therapeutic targets. This chapter highlights the innovations and challenges of NMR-based metabolomics platform and its applications in cancer research.作者: Pepsin 時(shí)間: 2025-3-26 13:05
Xiaochun Wang,Xiali Wang,Mitch Wilkesbolism in cancer cells remains limited, and the investigations of such processes and related pathways are certainly warranted to reveal the clinical relevance of fatty acid metabolism in cancer diagnosis and therapy.作者: defile 時(shí)間: 2025-3-26 19:04 作者: Minatory 時(shí)間: 2025-3-26 23:51
NMR-Based Metabolomics,oth NMR data acquisition and analysis methods. Although metabolomics applications span a wide range of disciplines, a majority has focused on understanding, preventing, diagnosing, and managing human diseases. This chapter describes NMR-based methods relevant to the rapidly expanding metabolomics field.作者: objection 時(shí)間: 2025-3-27 04:24 作者: 遠(yuǎn)足 時(shí)間: 2025-3-27 05:58 作者: 谷類(lèi) 時(shí)間: 2025-3-27 12:26 作者: CERE 時(shí)間: 2025-3-27 13:53 作者: 主動(dòng)脈 時(shí)間: 2025-3-27 20:33
Ching-Fan Chung,Richard T. Baillieed. These analytical strategies mainly include the use of chiral chromatography medium to facilitate chromatographic separation of enantiomers prior to spectroscopy or mass spectrometry analysis and the use of chiral derivatization reagents to convert the enantiomers to diastereomers with differenti作者: A簡(jiǎn)潔的 時(shí)間: 2025-3-27 22:15 作者: Polydipsia 時(shí)間: 2025-3-28 05:39
Detection of N6-Methyladenine in Eukaryotes, and widespread distribution in ., indicating 6mA probably playing different functions in different species. Meanwhile, 6mA methylases and demethylases were found in fly, worm, and .. In this chapter, we will briefly review the distribution, regulation, and function of 6mA in eukaryotes and focus on作者: HALO 時(shí)間: 2025-3-28 09:17
Quantitative Analysis of Oncometabolite 2-Hydroxyglutarate,ed. These analytical strategies mainly include the use of chiral chromatography medium to facilitate chromatographic separation of enantiomers prior to spectroscopy or mass spectrometry analysis and the use of chiral derivatization reagents to convert the enantiomers to diastereomers with differenti作者: 補(bǔ)充 時(shí)間: 2025-3-28 11:27
,HIF-1α Metabolic Pathways in Human Cancer, pivotal in both physiology and pathology..As we gain knowledge on the molecular mechanisms underlying the regulation of HIF-1, a great focus has been placed on elucidating the cellular function of HIF-1, particularly the role of HIF-1 in cancer pathogenesis pathways such as proliferation, invasion,作者: OWL 時(shí)間: 2025-3-28 17:29
Book 2021, mass spectrometry imaging for single cell metabolomics and functional metabolomics. ?In addition, the book highlights new discoveries in cancer metabolism such as hypoxia inducible factor pathway, isocitrate dehydrogenase 1 mutation and oncometabolites. Finally, contributors focus on the translati作者: ferment 時(shí)間: 2025-3-28 20:38
0065-2598 addition, the book highlights new discoveries in cancer metabolism such as hypoxia inducible factor pathway, isocitrate dehydrogenase 1 mutation and oncometabolites. Finally, contributors focus on the translati978-3-030-51652-9Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 黃瓜 時(shí)間: 2025-3-29 02:54 作者: incision 時(shí)間: 2025-3-29 05:56
New Developments in Singularity Theorysensitive than mass spectrometry, this analytical platform has numerous characteristics including its high reproducibility and quantitative abilities, its nonselective and noninvasive nature, and the ability to identify unknown metabolites in complex mixtures and trace the downstream products of iso作者: 彎腰 時(shí)間: 2025-3-29 10:52
https://doi.org/10.1007/978-3-319-95756-2rectly from lipid extracts of biological samples by mass spectrometry. This approach possesses advantages of high throughput and quantitative accuracy, especially in absolute quantification. As cancer research deepens at the level of quantitative biology and metabolomics, the demand for lipidomics a作者: Negotiate 時(shí)間: 2025-3-29 11:31
Can Chen,Wolfgang O. Eisenhut,Thanh Ngoand sensitivity for analysis of complex biological samples. In the last decade, GC?×?GC-MS has been increasingly applied to the discovery of metabolite biomarkers and elucidation of metabolic mechanisms in human diseases. The recent development of coupling GC?×?GC with a high-resolution mass spectro作者: catagen 時(shí)間: 2025-3-29 16:53 作者: 未成熟 時(shí)間: 2025-3-29 23:16
https://doi.org/10.1007/978-3-319-42571-9okaryotic species, but only existed in a few lower eukaryotes. In prokaryotes, 6mA plays an important role in restriction-modification, DNA replication, and DNA mismatch repair. Because of the too low abundance of 6mA, it was long-stalled whether 6mA existed in multicellular eukaryotes and playing a作者: FLOAT 時(shí)間: 2025-3-30 01:56
Yang Li,Xin He,Haiying Wang,Jianguo Suno the lack of specific and highly reliable methods. To better understand the diagnosis, pathogenesis, and treatment of these diseases, systems biology-driven metabolomics goes beyond the annotated phenotype and better targets the functions than conventional approaches. As a novel strategy for analys作者: hyperuricemia 時(shí)間: 2025-3-30 05:05 作者: 哭得清醒了 時(shí)間: 2025-3-30 10:58
Bryan Campbell,John W. Galbraithrong biomarkers of cancer initiation and progression, increasing evidences suggest that metabolic alteration tuned by oncogenic drivers contributes to the occurrence and development of cancers rather than just being a hallmark of cancer. With this notion, targeting cancer metabolism holds promise as作者: crease 時(shí)間: 2025-3-30 13:02 作者: 有權(quán)威 時(shí)間: 2025-3-30 17:52
Ching-Fan Chung,Richard T. Baillie2-hydroxyglutarate (2HG). 2HG is a potent competitor of α-ketoglutarate (α-KG) and can inhibit multiple α-KG-dependent dioxygenases that are critical for regulating the metabolic and epigenetic state of cells. The accumulation of 2HG contributes to elevated risk of malignant tumors. 2HG carries an a作者: Meager 時(shí)間: 2025-3-30 22:24 作者: fiction 時(shí)間: 2025-3-31 03:47
Shada Abuhattum,Amit Gefen,Daphne Weihser metabolomics. CE offers fast and high-resolution separation of charged analytes from a very small amount of sample. When coupled to MS, it represents a powerful analytical technique enabling identification and quantification of metabolites in biological samples. Several issues need to be addresse作者: 支柱 時(shí)間: 2025-3-31 05:45
Xiaochun Wang,Xiali Wang,Mitch Wilkesx biological samples, such as biofluids (plasma, serum, and urine), cells, tissue extracts, and even intact organs. Therefore, NMR-based metabolomics, a mainstream metabolomic platform, has been extensively applied in many research fields, including pharmacology, toxicology, pathophysiology, nutriti作者: 牢騷 時(shí)間: 2025-3-31 11:00 作者: 寒冷 時(shí)間: 2025-3-31 14:00
Xiaochun Wang,Xiali Wang,Mitch Wilkestain human cancers. Cancer cells can redirect metabolic pathways to meet energy demands through the regulation of fatty acid metabolism. The importance of de novo fatty acid synthesis and fatty acid oxidation in cancer cells suggests fatty acid metabolism may be targeted for anticancer treatment thr作者: Gratuitous 時(shí)間: 2025-3-31 20:18 作者: 光亮 時(shí)間: 2025-4-1 00:39 作者: 外向者 時(shí)間: 2025-4-1 04:57 作者: Presbycusis 時(shí)間: 2025-4-1 07:44
Cancer Metabolomics978-3-030-51652-9Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: Onerous 時(shí)間: 2025-4-1 10:59
https://doi.org/10.1007/978-3-030-51652-9cancer metabolomics; tracer-based metabolomics; data analysis tools for metabolomics; biomarker discove
