標(biāo)題: Titlebook: Cancer Genome and Tumor Microenvironment; Andrei Thomas-Tikhonenko Book 2010 Springer-Verlag New York 2010 Chromosom.angiogenesis.cell.gen [打印本頁] 作者: lexicographer 時間: 2025-3-21 18:38
書目名稱Cancer Genome and Tumor Microenvironment影響因子(影響力)
書目名稱Cancer Genome and Tumor Microenvironment影響因子(影響力)學(xué)科排名
書目名稱Cancer Genome and Tumor Microenvironment網(wǎng)絡(luò)公開度
書目名稱Cancer Genome and Tumor Microenvironment網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Cancer Genome and Tumor Microenvironment被引頻次
書目名稱Cancer Genome and Tumor Microenvironment被引頻次學(xué)科排名
書目名稱Cancer Genome and Tumor Microenvironment年度引用
書目名稱Cancer Genome and Tumor Microenvironment年度引用學(xué)科排名
書目名稱Cancer Genome and Tumor Microenvironment讀者反饋
書目名稱Cancer Genome and Tumor Microenvironment讀者反饋學(xué)科排名
作者: 商店街 時間: 2025-3-21 20:34
PI3K/AKT Pathway and the Epithelial-Mesenchymal Transitionhibitor .. By some estimates, . carries gain-of-function mutations in 32% of colorectal cancers, 36% of hepatocellular carcinomas, 36% of endometrial carcinomas, 25% of breast carcinomas, 15% of anaplastic oligodendrogliomas, and 5% of medulloblastomas and anaplastic astrocytomas (recently reviewed 作者: linear 時間: 2025-3-22 01:03 作者: osculate 時間: 2025-3-22 07:32 作者: Consensus 時間: 2025-3-22 08:59 作者: 閃光你我 時間: 2025-3-22 15:08 作者: 閃光你我 時間: 2025-3-22 18:49 作者: ARCHE 時間: 2025-3-23 01:07
Myc and Control of Tumor Neovascularization control of a heavy chain gene enhancer (Dalla-Favera et al. 1982; Taub et al. 1982). Additionally, double minute chromosomes (dmin) containing amplified copies of the c-Myc gene are commonly detected in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) (Storlazzi et al. 2004). In par作者: Barrister 時間: 2025-3-23 02:17 作者: xanthelasma 時間: 2025-3-23 05:45
Ink4a Locus: Beyond Cell Cycleactivation of p16 include melanoma, adenocarcinoma of the breast, squamous cell carcinomas of the lung, pancreatic adenocarcinomas, and colorectal carcinomas (Baylin et al. 1998; Pollack, Pearson, and Hayward 1996). In pancreatic adenocarcinoma, the frequency of p16 inactivation approaches 100% (Cal作者: anesthesia 時間: 2025-3-23 13:20 作者: 話 時間: 2025-3-23 16:21
HGF/c-MET Signaling in Advanced Cancersease, which is caused by inactivation of the VHL gene –( see Chapter 6). RCCP genes map to several loci; one of each on 7q31.1-q34 encodes the c-Met oncoprotein (Schmidt et al. 1997). In the original publication, missense mutations in the tyrosine kinase domain of the MET gene were found both in the作者: 個阿姨勾引你 時間: 2025-3-23 21:05 作者: choroid 時間: 2025-3-23 22:41 作者: 種子 時間: 2025-3-24 05:20
TGF-β Signaling Alterations in Neoplastic and Stromal Cellsse, a condition characterized by hyperostosis and sclerosis of the diaphyses of long bones (Janssens et al., 2000; Kinoshita et al., 2000). However, mutations in the TGFB genes do not appear to occur in cancer. In contrast, type I and II TGF-β receptors and their downstream effectors SMADs are often作者: 無聊點好 時間: 2025-3-24 07:29 作者: Guaff豪情痛飲 時間: 2025-3-24 12:12 作者: 戲服 時間: 2025-3-24 16:57 作者: GENUS 時間: 2025-3-24 22:17
Bacterial Efflux Pump Inhibitors, could occur via aberrant Akt signaling, direct somatic mutations in . are frequent in epithelial tumors such as diffuse-type gastric and lobular breast cancers, where they can be found in up to 50% of primary neoplasms (Berx et al. 1998). . mutations were also observed in primary endometrial and ov作者: 爭吵 時間: 2025-3-25 00:32
Lin Wang,Minghu Jiang,Stefan W?lflk.a. ARHH). This gene has been found to be rearranged in non-Hodgkin’s lymphomas and multiple myeloma, along with mutations in the 5.UTR in diffuse large cell lymphomas (Preudhomme et al. 2000; Pasqualucci et al. 2001). The common rearrangement found in these hematopoietic cancers is caused by a t(3作者: 字謎游戲 時間: 2025-3-25 04:45
https://doi.org/10.1007/978-3-540-74341-5ter et al. 1993). The hallmark of this disorder is the occurrence of schwannomas and other central nervous system tumors, such as multiple meningiomas. Both somatic and germline mutations were discovered in NF2 patients and in NF2-related tumors. Loss of the wild-type allele was demonstrated in 75% 作者: 平 時間: 2025-3-25 11:31
https://doi.org/10.1007/978-3-540-74341-5gnant tumors. The most frequent tumors are hemangioblastoma (HB) in the central nervous system (CNS), pheochromocytoma (Pheo), and renal-cell carcinoma of the clear-cell type (RCC). VHL families have been subdivided into those with a low risk of pheochromocytoma (type 1 VHL disease) and those with a作者: infringe 時間: 2025-3-25 14:40
https://doi.org/10.1007/978-3-540-74341-5ears, during which various laboratories were zooming in on viral oncogenes (Malumbres and Barbacid, 2003), in 1981, the laboratory led by Robert Weinberg succeeded in transferring DNA sequences from human cancer cells to immortalized murine fibroblasts (NIH-3T3), causing their overt malignant transf作者: CRAMP 時間: 2025-3-25 16:46
https://doi.org/10.1007/978-3-540-74341-5 control of a heavy chain gene enhancer (Dalla-Favera et al. 1982; Taub et al. 1982). Additionally, double minute chromosomes (dmin) containing amplified copies of the c-Myc gene are commonly detected in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) (Storlazzi et al. 2004). In par作者: CROAK 時間: 2025-3-25 20:55
https://doi.org/10.1007/978-3-540-74341-5half of all human cancers carry direct mutations of the p53 coding region. In addition to sporadic mutations in human cancer, inherited mutations in . cause a genetic predisposition to cancer called Li–Fraumeni syndrome. Individuals with Li–Fraumeni exhibit early onset of a wide variety of cancers i作者: 滲透 時間: 2025-3-26 00:43
https://doi.org/10.1007/978-3-540-74341-5activation of p16 include melanoma, adenocarcinoma of the breast, squamous cell carcinomas of the lung, pancreatic adenocarcinomas, and colorectal carcinomas (Baylin et al. 1998; Pollack, Pearson, and Hayward 1996). In pancreatic adenocarcinoma, the frequency of p16 inactivation approaches 100% (Cal作者: craving 時間: 2025-3-26 07:21 作者: Hay-Fever 時間: 2025-3-26 10:10 作者: colloquial 時間: 2025-3-26 13:20
https://doi.org/10.1007/978-3-642-81392-4o be promoting tumor cell detachment and invasion. However, in recent years several inhibitory roles in cancer progression have been attributed to matrix metalloproteinases and also members of the adamalysin family. In a recent comprehensive genetic screen of breast and colorectal cancer mutations, 作者: 百科全書 時間: 2025-3-26 17:10 作者: Camouflage 時間: 2025-3-26 22:49
New Antiviral Agent for Influenza: Baloxavirse, a condition characterized by hyperostosis and sclerosis of the diaphyses of long bones (Janssens et al., 2000; Kinoshita et al., 2000). However, mutations in the TGFB genes do not appear to occur in cancer. In contrast, type I and II TGF-β receptors and their downstream effectors SMADs are often作者: 急急忙忙 時間: 2025-3-27 04:23
Andrei Thomas-TikhonenkoReviews how tumor microenvironment and progression are “hard-wired” at the genetic level.Includes supplementary material: 作者: Cardiac-Output 時間: 2025-3-27 06:49 作者: consolidate 時間: 2025-3-27 13:24 作者: 津貼 時間: 2025-3-27 13:36 作者: 歡笑 時間: 2025-3-27 21:17
Cancer Genome and Tumor Microenvironment978-1-4419-0711-0Series ISSN 2626-1456 Series E-ISSN 2626-1464 作者: 暫時過來 時間: 2025-3-28 00:47 作者: INERT 時間: 2025-3-28 04:18 作者: 構(gòu)成 時間: 2025-3-28 10:14
https://doi.org/10.1057/9781137312655bed in almost every tumor type studied (reviewed in Bellacosa et al., 2005; Brugge et al., 2007). While many of the downstream effectors of the AKT pathway are involved in cell autonomous processes (i.e., cell cycle and apoptosis), the following chapter will focus on the implications of aberrant AKT作者: LIEN 時間: 2025-3-28 12:04 作者: 整潔 時間: 2025-3-28 17:19 作者: Bone-Scan 時間: 2025-3-28 21:16
PI3K/AKT Pathway and the Epithelial-Mesenchymal Transitionbed in almost every tumor type studied (reviewed in Bellacosa et al., 2005; Brugge et al., 2007). While many of the downstream effectors of the AKT pathway are involved in cell autonomous processes (i.e., cell cycle and apoptosis), the following chapter will focus on the implications of aberrant AKT作者: Conflict 時間: 2025-3-29 02:30 作者: 絕食 時間: 2025-3-29 04:55 作者: figure 時間: 2025-3-29 09:36
https://doi.org/10.1007/978-3-540-74341-5usion protein of truncated moesin and anaplastic lymphoma kinase was identified (Tort et al. 2001). However, ERM proteins are important regulators of the Rho GTPases (see Chapter .), firmly implicating them in the control of cancer cell motility and invasion.作者: 合唱隊 時間: 2025-3-29 13:33 作者: CLAN 時間: 2025-3-29 16:52
Direct Antiviral Agents for Hepatitis Cn of PDGF by tumor cells and/or higher levels of expression of PDGF receptors on stromal fibroblasts (Ebert et al., 1995). In the following chapter, we discuss the fibroblast-to-myofibroblast transition and how stromal cells may impact tumor evolution.作者: licence 時間: 2025-3-29 21:40 作者: 法律的瑕疵 時間: 2025-3-30 02:41 作者: scotoma 時間: 2025-3-30 05:46 作者: EVICT 時間: 2025-3-30 08:13 作者: Atrium 時間: 2025-3-30 15:50 作者: 控訴 時間: 2025-3-30 19:17
HGF/c-MET Signaling in Advanced Cancers germlines of affected patients and in a subset of sporadic papillary renal carcinomas. Additionally, tumors from RCCP patients commonly show trisomy of chromosome 7 harboring non-random duplication of the mutant MET allele (Zhuang et al. 1998).作者: Schlemms-Canal 時間: 2025-3-31 00:10
2626-1456 or suppressor genes had been traditionally studied in the context of cell proliferation, differentiation, senescence, and survival, four relatively cell-autonomous processes. Consequently, in the late ’80s-early ’90s, neoplastic growth was described largely as an imbalance between net cell accumulat作者: DEMUR 時間: 2025-3-31 02:20
Bacterial Efflux Pump Inhibitors,st cancers, where they can be found in up to 50% of primary neoplasms (Berx et al. 1998). . mutations were also observed in primary endometrial and ovarian carcinomas, albeit with a lower frequency (Risinger et al. 1994; Muta et al. 1996). The consequences of these mutations for EMT and tumor cell invasion are discussed below.作者: 字謎游戲 時間: 2025-3-31 06:54
https://doi.org/10.1007/978-3-540-74341-5erg succeeded in transferring DNA sequences from human cancer cells to immortalized murine fibroblasts (NIH-3T3), causing their overt malignant transformation (Malumbres and Barbacid, 2003; Karnoub and Weinberg, 2008).
