標(biāo)題: Titlebook: Cancer Drug Resistance; Beverly A. Teicher Book 2006 Humana Press 2006 angiogenesis.cancer.cytotoxicity.drug.drug resistance.hormones.imag [打印本頁(yè)] 作者: 調(diào)停 時(shí)間: 2025-3-21 19:01
書(shū)目名稱(chēng)Cancer Drug Resistance影響因子(影響力)
書(shū)目名稱(chēng)Cancer Drug Resistance影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)Cancer Drug Resistance網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱(chēng)Cancer Drug Resistance網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱(chēng)Cancer Drug Resistance被引頻次
書(shū)目名稱(chēng)Cancer Drug Resistance被引頻次學(xué)科排名
書(shū)目名稱(chēng)Cancer Drug Resistance年度引用
書(shū)目名稱(chēng)Cancer Drug Resistance年度引用學(xué)科排名
書(shū)目名稱(chēng)Cancer Drug Resistance讀者反饋
書(shū)目名稱(chēng)Cancer Drug Resistance讀者反饋學(xué)科排名
作者: Condescending 時(shí)間: 2025-3-21 22:26 作者: ETHER 時(shí)間: 2025-3-22 04:03
Gy. Csom,é. M. Zsolnay,E. J. Szondimechanisms contributing to the resistance of tumor stem cells to cytotoxic agents may involve increased efficiency of DNA replication and repair mechanisms in stem cells, changes in cell cycle parameters, and the overexpression of antiapoptotic and transporter proteins in these cell populations..The作者: rectum 時(shí)間: 2025-3-22 06:53 作者: 鋼筆記下懲罰 時(shí)間: 2025-3-22 10:23 作者: 從屬 時(shí)間: 2025-3-22 13:56
Compact Neutron Generator for BNCTr ABCG2, may have confounded the results. A single-nucleotide polymorphism (SNP) that limits the expression of P-gp could prevent inhibitor therapy from benefiting patients, and increase toxicity as well. The goal of this chapter is to evaluate new directions in the study of ABC transporters in mult作者: 從屬 時(shí)間: 2025-3-22 18:11 作者: 毗鄰 時(shí)間: 2025-3-22 21:14 作者: crease 時(shí)間: 2025-3-23 04:04
Cancer Stem Cells Implications for Development of More Effective Therapiesmechanisms contributing to the resistance of tumor stem cells to cytotoxic agents may involve increased efficiency of DNA replication and repair mechanisms in stem cells, changes in cell cycle parameters, and the overexpression of antiapoptotic and transporter proteins in these cell populations..The作者: 浮雕寶石 時(shí)間: 2025-3-23 07:05 作者: 小歌劇 時(shí)間: 2025-3-23 11:18 作者: GRIN 時(shí)間: 2025-3-23 16:36 作者: 背帶 時(shí)間: 2025-3-23 19:14
Cisplatin Resistances coexist to create a complex multifaceted dilemma, which confounds cancer treatment strategies. However, additional platinumbased agents with different spectrums of antitumor activity are entering the clinic, but it is likely that more-potent leads may be identified from among the large reservoir o作者: 小鹿 時(shí)間: 2025-3-24 01:24
The Cycle Between Angiogenesis, Perfusion, and Hypoxia in Tumorsance, enhanced invasion, and metastasis. Results indicate that concurrent targeting of both tumor and endothelial cells may be of central importance in improving treatment responses to both radiation and chemotherapy.作者: Lacunar-Stroke 時(shí)間: 2025-3-24 03:01
Tumor Oxygenation and Treatment Responsession. This chapter discusses recent research focused on methods of measuring tumor hypoxia accurately and extensively, with the aim of tailoring treatment on an individual patient basis. Examples of therapeutic approaches designed to exploit tumor hypoxia directly or indirectly, are discussed.作者: UTTER 時(shí)間: 2025-3-24 09:08 作者: EWER 時(shí)間: 2025-3-24 10:42
Book 2006 and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.作者: 充氣球 時(shí)間: 2025-3-24 17:00 作者: habitat 時(shí)間: 2025-3-24 22:51
Tumor Site Implantation and Animal Model Selection in Oncologypretation of result with early stage drug candidates must be carefully considered..In this chapter, we review a number of studies that support the notion that tumor implantation site represents a critical determinant for the successful and meaningful efficacy evaluation of chemotherapeutic agents.作者: 獎(jiǎng)牌 時(shí)間: 2025-3-25 02:22 作者: dandruff 時(shí)間: 2025-3-25 03:19 作者: Ingest 時(shí)間: 2025-3-25 10:07
https://doi.org/10.1007/978-1-4613-2940-4ines. Each of these interactions can influence the sensitivity of the tumor cells to treatment-induced apoptosis and can therefore affect the outcome of therapy. The pathways responsible for these effects are just beginning to be elucidated.作者: CRACK 時(shí)間: 2025-3-25 13:39 作者: 粗語(yǔ) 時(shí)間: 2025-3-25 16:04 作者: Infiltrate 時(shí)間: 2025-3-25 20:55 作者: 蛙鳴聲 時(shí)間: 2025-3-26 01:56 作者: 是限制 時(shí)間: 2025-3-26 04:30
Per Munck af Rosensch?ld M.Sc., Ph.D.dings highlight the importance of these targets in the creation of future novel anticancer drugs. This chapter gives a brief overview of the importance of both GSH and GST in the response to anticancer drug resistance, and highlights some of the anticancer drugs currently being investigated at various stages in the process from lab to clinic.作者: Apoptosis 時(shí)間: 2025-3-26 11:19
Oncogenes and Tumor Suppressor Genes in Therapeutic Resistancenical results. In the not-too-distant future, refinement and commercialization of pharmacogenomic tests in cancer will enable more-accurate predictions regarding responsiveness of individual patients to new and established agents. These data will also enable understanding of pathways of drug resistance and ways to overcome it.作者: Hypomania 時(shí)間: 2025-3-26 15:56
PET Imaging of Response and Resistance to Cancer Therapy have undergone preliminary testing in patients. Examples showing how positron emission tomography imaging can be used to (1) assess the therapeutic target, (2) identify resistance factors, and (3) measure early response are described.作者: 一大塊 時(shí)間: 2025-3-26 20:25 作者: 旋轉(zhuǎn)一周 時(shí)間: 2025-3-26 23:09 作者: violate 時(shí)間: 2025-3-27 04:06
2196-9906 cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, an作者: inclusive 時(shí)間: 2025-3-27 09:12 作者: Wordlist 時(shí)間: 2025-3-27 12:52
Californium-252 as a Neutron Source for BNCTs. This chapter focuses on recent experimental evidence concerning two of the features most commonly encountered in multidrug resistant cancer cells: (over)expression of multidrug transporters and disabling of apoptotic pathways.作者: 晚間 時(shí)間: 2025-3-27 15:49 作者: 脆弱帶來(lái) 時(shí)間: 2025-3-27 21:48
Molecular Determinants of Intrinsic Multidrug Resistance in Cancer Cells and Tumorss. This chapter focuses on recent experimental evidence concerning two of the features most commonly encountered in multidrug resistant cancer cells: (over)expression of multidrug transporters and disabling of apoptotic pathways.作者: Stress 時(shí)間: 2025-3-28 00:24 作者: Mhc-Molecule 時(shí)間: 2025-3-28 05:05
Influence of Tumor pH on Therapeutic Responselysis by the tumor cells. In general, the extracellular pH (pHe) in human tumors is below 7.0, whereas the intracellular pH (pHi) is maintained at neutral range, i.e.,>7.0, by powerful pHi control mechanisms. The low pHe and the significant gradients between pHe and pHi affect markedly the response 作者: Intrepid 時(shí)間: 2025-3-28 08:43 作者: BILL 時(shí)間: 2025-3-28 12:20 作者: FECT 時(shí)間: 2025-3-28 17:01
PET Imaging of Response and Resistance to Cancer Therapyochemical and molecular imaging can complement existing in vitro assay methods and is likely to play a key role in early drug testing and development, as well as future clinical practice. Imaging is ideally suited to assessing the spatial and temporal heterogeneity of cancer and to measure in vivo d作者: Lobotomy 時(shí)間: 2025-3-28 20:50
Cancer Stem Cells Implications for Development of More Effective Therapiesble. Recent work has suggested that most, if not all, malignancies are driven by a small subpopulation of cells that have stem cell characteristics. These “tumor stem cells” are thought to arise either from normal tissue stem cells or from early progenitor cells through dysregulation of self-renewal作者: GRILL 時(shí)間: 2025-3-28 23:50
Therapeutic Resistance in Leukemiaand collateral sensitivity. These in vivo models have been used for the evaluation of new compounds of potential clinical interest. Crossresistance data coupled with knowledge of the mechanisms of resistance operative in the drug-resistant leukemias may identify useful guides for patient selection f作者: GLIB 時(shí)間: 2025-3-29 06:03 作者: 悠然 時(shí)間: 2025-3-29 11:19
In Vivo Resistancerug. These tumor lines have been used to extend understanding of drug resistance in a host organism. It is becoming clear as our knowledge of growth factors and cytokines has increased that the proliferation and metabolism of tumor cells, like those of normal cells, are influenced by these naturally作者: DOSE 時(shí)間: 2025-3-29 11:49 作者: Leisureliness 時(shí)間: 2025-3-29 16:15
The Microenvironment and Drug Resistance microenvironment can significantly affect the success of chemotherapy. The interactions between the tumor cells and their environment can be classified into three main categories: (1) cell-cell contacts, (2) interactions with the extracellular matrix, and (3) interactions with soluble factors/cytok作者: Osmosis 時(shí)間: 2025-3-29 23:44 作者: fetter 時(shí)間: 2025-3-30 03:19
Metallothioneins in Drug Resistancec and copper), and some that are both toxic and not required for cell function (for example, cadmium and mercury). A role for MTs in metabolism and detoxication of heavy metals is strongly suggested by the sensitivity of many MT genes to induction by heavy metals and the ability of MT proteins to bi作者: 豐富 時(shí)間: 2025-3-30 08:02 作者: 圓柱 時(shí)間: 2025-3-30 08:12
New and Revised Concepts in Multidrug Resistanceen well described in vitro in laboratory models. The extent to which multidrug transporters are responsible for clinical drug resistance has been more difficult to determine. In one sense, P-gp can be viewed as a molecular target that was tested in the clinic before there was an adequate understandi作者: LURE 時(shí)間: 2025-3-30 14:19
Cisplatin Resistanceclinical management of cancers over the last three decades. It is similar to classical alkylating agents, in that the central platinum atom interacts covalently with DNA to also form adducts, which are the cytotoxic lesions. When these adducts are detected by damage recognition proteins, signals are作者: heterogeneous 時(shí)間: 2025-3-30 20:16
Cancer Drug Resistance978-1-59745-035-5Series ISSN 2196-9906 Series E-ISSN 2196-9914 作者: Pulmonary-Veins 時(shí)間: 2025-3-30 22:04 作者: arrhythmic 時(shí)間: 2025-3-31 01:13
Cancer Drug Discovery and Developmenthttp://image.papertrans.cn/c/image/221094.jpg作者: vertebrate 時(shí)間: 2025-3-31 05:12
Gordon J. Kearley,Vanessa K. Petersonlated angiogenesis, instability in perfusion, and hypoxia. Interactions between tumor and endothelial cells occur during tumor growth and in response to therapy. These interactions are of central importance in establishing codependence that contributes to promotion of cell survival, treatment resist作者: 胎兒 時(shí)間: 2025-3-31 12:22
Materials for the Nuclear Energy Sectorlysis by the tumor cells. In general, the extracellular pH (pHe) in human tumors is below 7.0, whereas the intracellular pH (pHi) is maintained at neutral range, i.e.,>7.0, by powerful pHi control mechanisms. The low pHe and the significant gradients between pHe and pHi affect markedly the response 作者: 鞭打 時(shí)間: 2025-3-31 14:19 作者: agglomerate 時(shí)間: 2025-3-31 18:57
Gy. Csom,é. M. Zsolnay,E. J. Szondime aspects of drug resistance, such as the ability to repopulate the tumor mass by clonogenic/stem cell subsets or adhesion/aggregation-dependent changes in responsiveness to therapy may be related to genetic tumor progression, genetic instability, and expression of oncogenic proteins. Combinations 作者: 茁壯成長(zhǎng) 時(shí)間: 2025-3-31 22:19 作者: 不知疲倦 時(shí)間: 2025-4-1 05:11
Gy. Csom,é. M. Zsolnay,E. J. Szondible. Recent work has suggested that most, if not all, malignancies are driven by a small subpopulation of cells that have stem cell characteristics. These “tumor stem cells” are thought to arise either from normal tissue stem cells or from early progenitor cells through dysregulation of self-renewal作者: MAOIS 時(shí)間: 2025-4-1 06:51
