標(biāo)題: Titlebook: Cancer Cytogenetics; Methods and Protocol John Swansbury Book 20031st edition Humana Press 2003 [打印本頁] 作者: JAR 時間: 2025-3-21 19:23
書目名稱Cancer Cytogenetics影響因子(影響力)
書目名稱Cancer Cytogenetics影響因子(影響力)學(xué)科排名
書目名稱Cancer Cytogenetics網(wǎng)絡(luò)公開度
書目名稱Cancer Cytogenetics網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Cancer Cytogenetics被引頻次
書目名稱Cancer Cytogenetics被引頻次學(xué)科排名
書目名稱Cancer Cytogenetics年度引用
書目名稱Cancer Cytogenetics年度引用學(xué)科排名
書目名稱Cancer Cytogenetics讀者反饋
書目名稱Cancer Cytogenetics讀者反饋學(xué)科排名
作者: 去掉 時間: 2025-3-21 22:59
Louisa E. Chapman M.D., M.S.P.H.Solid tumors comprise approx 95% of all malignancies, but account for only a little over 25% of cases in published cytogenetic studies. The main reasons are:作者: commodity 時間: 2025-3-22 02:59 作者: Astigmatism 時間: 2025-3-22 04:55 作者: 細胞膜 時間: 2025-3-22 09:56
Methods in Molecular Biologyhttp://image.papertrans.cn/c/image/221083.jpg作者: 大笑 時間: 2025-3-22 14:59
Kathryn M. Albers,Brian M. Davistitute only about 20% of all cancers. It follows that most of what is known about the clinical applications of cytogenetic studies has been derived from hematologic malignancies. More recently, however, there has been a huge expansion in knowledge of the recurrent abnormalities in some solid tumors,作者: 大笑 時間: 2025-3-22 19:49 作者: 來就得意 時間: 2025-3-22 21:58
Tracing with Radiolabeled Neurotrophinsases that are frankly malignant, such as acute myeloid leukemia (AML), and some that may be regarded as premalignant, such as the myeloproliferative disorders (MPD). A proportion of the premalignant group may progress to acute leukemia but they are serious diseases in their own right, often difficul作者: OWL 時間: 2025-3-23 04:37
Kathryn M. Albers,Brian M. Davishe cells are arrested and accumulated in metaphase or prometaphase by destroying (e.g., with colcemid) the mitotic spindle which would separate the chromatids. The cells are treated with a hypotonic solution to encourage spreading of the chromosomes. They are then fixed, after which they can be stor作者: abreast 時間: 2025-3-23 08:57 作者: STENT 時間: 2025-3-23 11:49 作者: 館長 時間: 2025-3-23 16:32
Stanley Perlman,D. Lori Wheelerlls from other diseases when standard laboratory processes are applied, in spite of the fact that karyotypically normal cells from the same sample can produce high-quality divisions under the same conditions. Thus it is of primary importance in the analysis of ALL preparations not simply to select t作者: Admire 時間: 2025-3-23 18:22
Thomas Wisniewski M.D.,Fernando Go?i the less primitive kinds of ALL, such as T-cell ALL and B-cell ALL, all kinds of lymphoma, the chronic lymphoproliferative disorders, and malignant myeloma. Most of these disorders are not as amenable to cytogenetic study as the acute leukemias and chronic myeloid leukemia; the number of published 作者: Bereavement 時間: 2025-3-24 02:10
https://doi.org/10.1007/978-3-319-33189-8yeloma, chronic lymphocytic leukemia, and other chronic lymphoproliferative diseases. They are also required for studies of acute lymphoblastic leukemia of mature T-cell or B-cell types. As mentioned in the previous chapter, most lymphoid cells are either T-lineage or B-lineage. During normal differ作者: Negligible 時間: 2025-3-24 02:24
Transmissible Spongiform Encephalopathies hematology and oncology. Tumor cytogenetics has for many years been dedicated almost exclusively to the study of hematological malignancies, mainly because these are more readily accessible. Important information has been obtained: cytogenetic changes in tumors are acquired, clonal abnormalities th作者: 禁止 時間: 2025-3-24 09:52
https://doi.org/10.1007/978-94-017-7509-0l, and experience generously spent on these techniques will do much to make the next stages easier: the analysis and interpretation of these metaphases. Much of the following subheadings provide practical advice about these important aspects of a cytogeneticist’s work. They are mainly derived from e作者: 山崩 時間: 2025-3-24 12:06
https://doi.org/10.1007/978-94-017-7509-0e could be recognized. Then it was discovered that chromosomes could be made to show a consistent pattern of lighter or darker stained segments (bands) by using fluorescent dyes (fluorochromes) such as atebrin and quinecrine, or by treatment with agents such as trypsin, detergent, or a salt solution作者: Haphazard 時間: 2025-3-24 18:49 作者: 背心 時間: 2025-3-24 20:35
Helmut Madersbacher,Jerzy B. Gajewski performed only on dividing cells and cannot detect cryptic rearrangements. The introduction of molecular cytogenetic techniques, such as fluorescence . hybridization (FISH), has revolutionized the field of cytogenetics by allowing the identification of complex and cryptic chromosomal abnormalities.作者: 該得 時間: 2025-3-24 23:40
Helmut Madersbacher,Jerzy B. Gajewskis have included developments in recombinant technology such as fluorescence . hybridization (FISH), a means of detecting chromosome rearrangements through the use of DNA-specific probes known as chromosome paints. Recent extensions to this painting technology are multiplex FISH (MFISH) (.) and spect作者: 哀求 時間: 2025-3-25 06:46 作者: GRAIN 時間: 2025-3-25 10:24 作者: defendant 時間: 2025-3-25 13:13 作者: 圍裙 時間: 2025-3-25 16:24
Kathryn M. Albers,Brian M. Davis and it is clear that in these, just as in the leukemias, cytogenetic abnormalities can help to define the diagnosis and to indicate clear prognostic differences. Consequently, cytogenetic studies of some solid tumors are now also moving out of the research environment and into routine clinical service.作者: restrain 時間: 2025-3-25 22:36 作者: ANTE 時間: 2025-3-26 00:36
Stanley Perlman,D. Lori Wheelerhe best available metaphases for analysis, or the malignant clone may not be sampled. In addition to this, some variation to routine procedures may enhance the quality and relative quantity of abnormal metaphases and facilitate accurate analysis.作者: 賠償 時間: 2025-3-26 06:41
Introduction, and it is clear that in these, just as in the leukemias, cytogenetic abnormalities can help to define the diagnosis and to indicate clear prognostic differences. Consequently, cytogenetic studies of some solid tumors are now also moving out of the research environment and into routine clinical service.作者: 心神不寧 時間: 2025-3-26 08:49
Cytogenetic Techniques for Myeloid Disorders,ed indefinitely. Fixed cells are spread on slides and air-dried. They can be stained immediately, but are usually first treated to induce banding patterns on the chromosomes to assist in their identification.作者: insomnia 時間: 2025-3-26 12:54
Chromosome Preparations from Bone Marrow in Acute Lymphoblastic Leukemia,he best available metaphases for analysis, or the malignant clone may not be sampled. In addition to this, some variation to routine procedures may enhance the quality and relative quantity of abnormal metaphases and facilitate accurate analysis.作者: Cubicle 時間: 2025-3-26 18:39 作者: Blanch 時間: 2025-3-27 00:06
1064-3745 tutorials on the fundamentals of human karyotypes and chromosome analysis, but also detailed discussions on how laboratories may optimally upgrade their repertoire of capabilities to include such newer complementary techniques as CGH, FISH, and M-FISH.978-1-59259-363-7Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: dictator 時間: 2025-3-27 02:39 作者: 一條卷發(fā) 時間: 2025-3-27 05:39 作者: Gobble 時間: 2025-3-27 12:57
Conventional Cytogenetic Techniques in the Diagnosis of Childhood Acute Lymphoblastic Leukemia,especially useful in diagnosing the leukemic subtype and predicting treatment outcome. Molecular analysis of genes adjacent to the breakpoints of specific translocations and the study of the functions of their gene products have helped to clarify the complex interactions that promote leuke-mogenesis and perpetuate the leukemic phenotype (.).作者: 臆斷 時間: 2025-3-27 16:18 作者: 發(fā)現(xiàn) 時間: 2025-3-27 19:25
Other Lymphoid Malignancies, the methods described here are Phytohemagglutinin (PHA) for T-cells (..), and 12-.-tetradecanoyl-phorbol-13-acetate (TPA) for B cells. Other B-cell mitogens are described in .. Be aware that no mitogen is absolutely specific to T cells or B cells (..).作者: daredevil 時間: 2025-3-27 22:31
Tracing with Radiolabeled Neurotrophinsabnormal cell, which usually tends to expand and eventually suppress or replace the growth and development of normal blood cells. This group of disorders includes the following: .The major clinical and cytogenetic features of the myeloid malignancies are summarized in the following subheadings.作者: 貧窮地活 時間: 2025-3-28 04:16
Carrie G. Causing,Freda D. Miller-B, common (cALL), and mature B stages. The last stage constitutes FAB type L3, which has a very close affinity with Burkitt lymphoma; these two disorders share identical cytogenetic abnormalities and both are now formally termed Burkitt cell lymphoma (BL).作者: Integrate 時間: 2025-3-28 09:43 作者: Obverse 時間: 2025-3-28 14:21 作者: Femish 時間: 2025-3-28 15:54
https://doi.org/10.1007/978-94-017-7509-0fessional guidelines drawn up to ensure that consistent and uniformly high standards of analysis are applied in all laboratories. Much the same principles are now being applied to the analysis of solid tumors.作者: apiary 時間: 2025-3-28 21:29
Helmut Madersbacher,Jerzy B. Gajewskindings are published and confirmed and become clinically useful, then research funding is likely to become unobtainable as the work is deemed to have become a service and should therefore be funded in the same way as other well-established clinical services such as hematology and biochemistry.作者: 克制 時間: 2025-3-29 01:30
Helmut Madersbacher,Jerzy B. Gajewskiabnormalities. There is also a schematic representation of the human karyotype, and several illustrations of karyotypes of normal chromosomes, stained in different ways. Every cytogeneticist needs to become familiar with the correct way of describing chromosomes and their abnormalities.作者: 剛開始 時間: 2025-3-29 04:47 作者: Tempor 時間: 2025-3-29 08:09 作者: 極肥胖 時間: 2025-3-29 14:17
Lymphoid Disorders Other than Common Acute Lymphoblastic Leukemia,malignant tissue, such as lymph node, and the cytogeneticist may have to make do with other, infiltrated tissue, such as blood or bone marrow. Although these can be successful for some types of malignancy, for other types the success rate is very low.作者: Fester 時間: 2025-3-29 17:44
Human Solid Tumors,ed for choice of treatment, patient stratification, and assessment of minimal disease. Furthermore, molecular investigations of recurrent cytogenetic changes have led to the discovery of genes that play a determining role in leukemia and oncogenesis in general.作者: SCORE 時間: 2025-3-29 22:02 作者: 解凍 時間: 2025-3-30 03:32
Some Difficult Choices in Cytogenetics,ndings are published and confirmed and become clinically useful, then research funding is likely to become unobtainable as the work is deemed to have become a service and should therefore be funded in the same way as other well-established clinical services such as hematology and biochemistry.作者: dialect 時間: 2025-3-30 05:31
Introduction to the Analysis of the Human G-Banded Karyotype,abnormalities. There is also a schematic representation of the human karyotype, and several illustrations of karyotypes of normal chromosomes, stained in different ways. Every cytogeneticist needs to become familiar with the correct way of describing chromosomes and their abnormalities.作者: 沙發(fā) 時間: 2025-3-30 11:54
Cytogenetic Studies in Hematologic Malignancies,ity. It was once thought that poor morphology alone, even in the absence of detectable abnormality, might be sufficient to identify a malignant clone. However tempting this explanation has been to anyone who has seen such coexisting populations, such a hypothesis has not been subsequently confirmed.作者: 可商量 時間: 2025-3-30 13:45 作者: 母豬 時間: 2025-3-30 16:40
FISH Techniques,tory. It is possible to study air-dried bone marrow or blood films, fresh tumor touch prints, and wax-embedded sections of solid tumors. The techniques are very similar to those described here (.,.). It is also possible to perform FISH studies on preparations that have already been banded and analyz作者: crumble 時間: 2025-3-30 21:43 作者: Rankle 時間: 2025-3-31 01:25
Solving Problems in Multiplex FISH,resents a useful tool for the genome-wide screening of chromosome rearrangement and is becoming increasingly practiced in both the research and diagnostic professions. It follows that a chapter on the use of these technologies is appropriately included in a series on the methods used in malignancy c作者: 花爭吵 時間: 2025-3-31 05:38
Shu-Hua Zhang,Xin-Fu Zhou,Robert A. Rushity. It was once thought that poor morphology alone, even in the absence of detectable abnormality, might be sufficient to identify a malignant clone. However tempting this explanation has been to anyone who has seen such coexisting populations, such a hypothesis has not been subsequently confirmed.作者: adjacent 時間: 2025-3-31 12:48
https://doi.org/10.1007/978-94-017-7509-0often of poor morphology, and tend to be involved in complex and subtle rearrangements; in such cases, conventional cytogenetic studies are unable to define fully the entire karyotype. This limitation has been overcome by the introduction of new techniques, known as . hybridization (ISH), which bind作者: 易達到 時間: 2025-3-31 15:40
Helmut Madersbacher,Jerzy B. Gajewskitory. It is possible to study air-dried bone marrow or blood films, fresh tumor touch prints, and wax-embedded sections of solid tumors. The techniques are very similar to those described here (.,.). It is also possible to perform FISH studies on preparations that have already been banded and analyz作者: Systemic 時間: 2025-3-31 21:05 作者: 縮短 時間: 2025-4-1 01:35 作者: 刪減 時間: 2025-4-1 05:18 作者: 生命層 時間: 2025-4-1 08:22
Cytogenetic Studies in Hematologic Malignancies,e consistent, reproducible results in almost all cases. It is therefore possible to refine and define a protocol that can be confidently used to provide an abundance of high-quality metaphases and prometaphases. For malignant cells, however, it can seem that every patient’s chromosomes have an idios作者: STALE 時間: 2025-4-1 11:03 作者: Encapsulate 時間: 2025-4-1 14:48 作者: 陳腐思想 時間: 2025-4-1 21:24
Acute Lymphoblastic Leukemia,he predominant cell cytology, in acute lymphoblastic leukemia (ALL), there are only three (.). Furthermore, for most practical purposes, FAB types L1 and L2 are almost indistinguishable. Of more importance than the morphology of the cells in ALL is the immunophenotype. Apart from identifying an enti作者: Foam-Cells 時間: 2025-4-1 23:47 作者: 尖牙 時間: 2025-4-2 06:09
