標(biāo)題: Titlebook: Calcium-Sensing Receptor; Naibedya Chattopadhyay,Edward M. Brown Book 2003 Springer Science+Business Media New York 2003 Calcium.biochemis [打印本頁] 作者: 可擴(kuò)大 時(shí)間: 2025-3-21 18:37
書目名稱Calcium-Sensing Receptor影響因子(影響力)
作者: 繁榮地區(qū) 時(shí)間: 2025-3-21 23:23
Functions of the Calcium-Sensing Receptor in the Gastrointestinal System, a review, I will also note where the CaR has not yet been reported in the mammalian gastrointestinal system, but, if present, may have functional implications. Let us agree at the outset that unequivocal evidence for the modulation of gastrointestinal function by the CaR requires the use of rescued作者: 表示向前 時(shí)間: 2025-3-22 02:37 作者: cutlery 時(shí)間: 2025-3-22 05:26
Terrorismus im Zeitalter der Globalisierung,eral hundred milligrams of Ca.. enter the skeleton owing to . formation of bone by osteoblasts on a daily basis. Local depletion of Ca.. will likely take place in the immediate vicinity of osteoblasts actively forming bone. Thus it is possible that the G protein-coupled, extracellular calcium (Ca..)作者: 暫時(shí)過來 時(shí)間: 2025-3-22 11:24
,Partnerschaften für Entwicklung?, a review, I will also note where the CaR has not yet been reported in the mammalian gastrointestinal system, but, if present, may have functional implications. Let us agree at the outset that unequivocal evidence for the modulation of gastrointestinal function by the CaR requires the use of rescued作者: 不能平靜 時(shí)間: 2025-3-22 12:57
https://doi.org/10.1007/978-3-658-20585-0.) and loricrin (.). In cultured epidermal keratinocytes, the concentration of extracellular Ca. [Ca.]. is an important regulator for differentiation (., .). Under conditions where [Ca.]. is 0.05 mM or lower, keratinocytes proliferate rapidly, express a basal cell phenotype, do not stratify or corni作者: 不能平靜 時(shí)間: 2025-3-22 19:47 作者: achlorhydria 時(shí)間: 2025-3-22 21:43
Calcium-sensing Receptor and Neoplastic Transformation,of colorectal cancer may be reduced by approximately 70% if daily calcium intake is raised from 800 to 1400 mg. The incidence of prostate cancer is also clearly linked to high fat consumption, whereas studies on a possible association with dietary calcium levels did not yield conclusive results (.,.).作者: KIN 時(shí)間: 2025-3-23 05:21
Book 2003able both for those who have been working in the field of Ca.2+.0-sensing as well as those who are new to this discipline. .Calcium-Sensing Receptor. is the nineteenth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.作者: 抗體 時(shí)間: 2025-3-23 07:35
,Zivilgesellschaft in Entwicklungsl?ndern,wever, that effectively lower the chronically elevated levels of PHT in hyperparathyroidism. It is conceivable that drugs which either increase or decrease the secretion of PHT from the parathyroid glands could be useful in treating the various forms of hyperparathyroidism and/or osteoporosis.作者: 公社 時(shí)間: 2025-3-23 09:57 作者: anticipate 時(shí)間: 2025-3-23 14:56 作者: 指令 時(shí)間: 2025-3-23 20:14
Expression and Functions of Calcium-Sensing Receptor in the Central Nervous System,for calcium-triggered calcium release) (.). In the former instance calcium homeostasis in the CNS is maintained by Ca. entry into neural cells by voltage-sensitive or ligand-gated calcium channels and Ca. release from the ER or calciosomes in case of the latter.作者: Anthropoid 時(shí)間: 2025-3-23 22:40 作者: 權(quán)宜之計(jì) 時(shí)間: 2025-3-24 05:09 作者: 為敵 時(shí)間: 2025-3-24 07:51 作者: Subjugate 時(shí)間: 2025-3-24 11:14
1566-0729 at is suitable both for those who have been working in the field of Ca.2+.0-sensing as well as those who are new to this discipline. .Calcium-Sensing Receptor. is the nineteenth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.978-1-4613-4861-097作者: 拘留 時(shí)間: 2025-3-24 15:05
,Besch?ftigungspolitik in Lateinamerika,yroid chief cells, renal cells, as well as thyroid C-cells, and those not participating in systemic calcium homeostasis, such as brain and breast cells (.). The CaR is well conserved across species (.–.). For instance, the amino acid sequences of CaRs from human, rat, and rabbit are more than 90% identical to that of the bovine CaR.作者: 河流 時(shí)間: 2025-3-24 21:57 作者: Gullible 時(shí)間: 2025-3-25 01:40
https://doi.org/10.1007/978-3-531-90156-5important metabolic modalities, perhaps contributing to other biochemical feedback loops. Depending on the composition of the local extracellular ., the CaR can sense variations in extracellular levels of:作者: Freeze 時(shí)間: 2025-3-25 03:23 作者: otic-capsule 時(shí)間: 2025-3-25 10:40
The Calcium-Sensing Receptor (CaR) and Human Disease,ed PTH secretion maintains the concentration of serum Ca.in humans within a narrow range (between 9.0 and 10.4 mg/dl). In several now well-described disorders resulting from alterations in the gene encoding the CaR (gene name CASR), this precise regulation of serum calcium concentration is disturbed.作者: Conclave 時(shí)間: 2025-3-25 12:59
Alternative Agonists and Modulators: Evidence that the Calcium-Sensing Receptor is a Multi-Modal Seimportant metabolic modalities, perhaps contributing to other biochemical feedback loops. Depending on the composition of the local extracellular ., the CaR can sense variations in extracellular levels of:作者: crescendo 時(shí)間: 2025-3-25 16:02
,Besch?ftigungspolitik in Lateinamerika,riety of receptor-mediated events. The levels of free calcium in the cytosol (Ca..), although dependent to some extent on extracellular calcium (Ca..), are much lower than the latter (100 nM vs. 1.1–1.3 mM) (.,.). Quite unlike Ca.., Ca.. fluctuates rapidly and over a wide range (10-fold or more) in response to hormonal and other stimuli (.).作者: 灌輸 時(shí)間: 2025-3-25 22:48
https://doi.org/10.1007/978-3-322-97579-9re complex and multi-layered, with numerous opportunities for cross-talk between pathways. Furthermore, the predominant biological response to activation of the CaR is highly cell-type specific, implying that presence or absence of specific signaling intermediaries may have a profound effect on the outcome.作者: 生氣的邊緣 時(shí)間: 2025-3-26 01:23
Terrorismus im Zeitalter der Globalisierung,ered at the glomerulus is usually reabsorbed in the proximal tubule (PT) with the remaining Ca. reabsorbed by the thick ascending limb of Henle’s loop (TAL) and more distal nephron segments (see figure 1 A). Sodium and calcium transport by the kidney generally occur in parallel such that there is a codependence of calcium and sodium transport (.).作者: 不真 時(shí)間: 2025-3-26 07:33
An Overview of Extracellular Calcium Homeostasis and the Roles of the CaR in Parathyroid and C-celllogical processes. Intracellular calcium is vital for regulating myriad cellular functions, such as differentiation, secretion, proliferation and motility, and it also acts as a cofactor in numerous enzymatic reactions (.). Equally importantly, it serves as an intracellular second messenger for a va作者: 調(diào)色板 時(shí)間: 2025-3-26 11:18
Structure-Function Relationship of the Extracellular Calcium-Sensing Receptor,R is expressed on the plasma membrane of a variety of cell types, including those involved in maintaining systemic calcium homeostasis, such as parathyroid chief cells, renal cells, as well as thyroid C-cells, and those not participating in systemic calcium homeostasis, such as brain and breast cell作者: Graphite 時(shí)間: 2025-3-26 12:54
Calcium Receptor-mediated Signaling,in coupled receptors (GPCR). Biological responses associated with activation of the CaR include regulation of hormone secretion, activation of ion channels, migration, proliferation, differentiation, and apoptosis. The mechanisms linking other G-protein coupled receptors to these diverse responses a作者: Perineum 時(shí)間: 2025-3-26 16:53 作者: Indecisive 時(shí)間: 2025-3-26 22:35 作者: Occupation 時(shí)間: 2025-3-27 02:06 作者: hauteur 時(shí)間: 2025-3-27 08:02
The Calcium-Sensing Receptor (CaR) and Human Disease,elped clarify the central and non-redundant role of the CaR in normal calcium homeostasis. Through its effects on kidney, bone, and intestine, regulated PTH secretion maintains the concentration of serum Ca.in humans within a narrow range (between 9.0 and 10.4 mg/dl). In several now well-described d作者: Kinetic 時(shí)間: 2025-3-27 12:10
Compounds Acting on the Parathyroid Calcium Receptor as Novel Therapies for Hyperparathyroidism or bone and blood. Its actions on bone are complex and PHT can stimulate net bone loss or formation depending upon temporal changes in the levels of circulating hormone. Chronically elevated levels of plasma PTH, as occurs in primary or secondary hyperparathyroidism, stimulate osteoclastic bone resorpt作者: phase-2-enzyme 時(shí)間: 2025-3-27 16:44 作者: 取消 時(shí)間: 2025-3-27 18:45 作者: 使害怕 時(shí)間: 2025-3-27 23:08
The Role of the Calcium Receptor in Calcium Regulated Keratinocyte Differentiation, by position, shape, polarity, morphology and state of differentiation of the keratinocytes. Keratinocytes in each epidermal layer express distinct biochemical markers. Keratin 5 (K5) and 14 (K14) are predominantly expressed in basal keratinocytes (.). In suprabasal cells, synthesis of differentiati作者: mitral-valve 時(shí)間: 2025-3-28 04:56 作者: 徹底明白 時(shí)間: 2025-3-28 09:12
Endocrine Updateshttp://image.papertrans.cn/c/image/220822.jpg作者: 隱語 時(shí)間: 2025-3-28 13:12 作者: Redundant 時(shí)間: 2025-3-28 18:20
978-1-4613-4861-0Springer Science+Business Media New York 2003作者: FLAT 時(shí)間: 2025-3-28 20:34 作者: Diluge 時(shí)間: 2025-3-29 01:56
,Besch?ftigungspolitik in Lateinamerika,R is expressed on the plasma membrane of a variety of cell types, including those involved in maintaining systemic calcium homeostasis, such as parathyroid chief cells, renal cells, as well as thyroid C-cells, and those not participating in systemic calcium homeostasis, such as brain and breast cell作者: 色情 時(shí)間: 2025-3-29 07:04
https://doi.org/10.1007/978-3-322-97579-9in coupled receptors (GPCR). Biological responses associated with activation of the CaR include regulation of hormone secretion, activation of ion channels, migration, proliferation, differentiation, and apoptosis. The mechanisms linking other G-protein coupled receptors to these diverse responses a作者: 不朽中國(guó) 時(shí)間: 2025-3-29 07:59
Terrorismus im Zeitalter der Globalisierung,ditions. Normally about 60% of the plasma calcium (100% of the ionized calcium) is filtered through the glomerular capillaries and is reabsorbed virtually along the entire nephron, with the exception of the thin descending and ascending limbs of Henle’s loop (.,.). Sixty-five percent of the Ca. filt作者: 退出可食用 時(shí)間: 2025-3-29 13:57
Terrorismus im Zeitalter der Globalisierung,lcium ion concentration (Ca..) underneath actively resorbing osteoclasts can rise as high as 8–40 mM (.). Therefore, it is likely that Ca.. within the immediate microenvironment of such osteoclasts would change substantially when this calcium is released. Indeed, during uncontrolled osteoclastic rel作者: 極小量 時(shí)間: 2025-3-29 16:49
,Partnerschaften für Entwicklung?,cium (Ca..) have been shown to increase serum levels of immunoreactive gastrin (1), to stimulate gastric acid secretion . (.), to modulate bile secretion (.,.) and to diminish rates of proliferation in colonocytes (.,.). This review will focus on the emerging body of work implicating the extracellul作者: 逃避現(xiàn)實(shí) 時(shí)間: 2025-3-29 23:10 作者: 營(yíng)養(yǎng) 時(shí)間: 2025-3-30 03:46 作者: 鄙視 時(shí)間: 2025-3-30 05:04
https://doi.org/10.1007/978-3-531-90156-5able 1). These findings suggest that the CaR is not only as a regulator of systemic calcium homeostasis but also mediates cellular responses to other important metabolic modalities, perhaps contributing to other biochemical feedback loops. Depending on the composition of the local extracellular ., t作者: sparse 時(shí)間: 2025-3-30 09:52
https://doi.org/10.1007/978-3-658-20585-0ophic factors. Calcium is also involved in long-term adaptive processes, such as memory. Such adaptive changes within an optimal range of intracellular Ca. (Ca..) play major roles during development and adult plasticity of the nervous system (.,.). However, when Ca.. rises too high and/or for too lo作者: insightful 時(shí)間: 2025-3-30 12:34 作者: photopsia 時(shí)間: 2025-3-30 17:05
Synthetische Biologie als Spiel?ern: For example, an increased risk of breast cancer is believed to result from high dietary fat and/or low intake of vitamin D and calcium (.,.,.). Similarly, it has been known for a long time that colorectal cancer shows a strong positive correlation with dietary fat, while low vitamin D and dieta
