標(biāo)題: Titlebook: Calcium in Drug Actions; Peter F. Baker (Professor Sc. D., F.R.S.) Book 1988 Springer-Verlag Berlin Heidelberg 1988 ATP.ATPase.Calcium.bon [打印本頁(yè)] 作者: Espionage 時(shí)間: 2025-3-21 19:41
書(shū)目名稱Calcium in Drug Actions影響因子(影響力)
書(shū)目名稱Calcium in Drug Actions影響因子(影響力)學(xué)科排名
書(shū)目名稱Calcium in Drug Actions網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Calcium in Drug Actions網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Calcium in Drug Actions被引頻次
書(shū)目名稱Calcium in Drug Actions被引頻次學(xué)科排名
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書(shū)目名稱Calcium in Drug Actions年度引用學(xué)科排名
書(shū)目名稱Calcium in Drug Actions讀者反饋
書(shū)目名稱Calcium in Drug Actions讀者反饋學(xué)科排名
作者: 歡騰 時(shí)間: 2025-3-21 20:17
Die ,sche Algebra. Anwendungen,rs on the topic have described a detailed examination of the energetics of calcium-ligand interactions, including both thermodynamic and kinetic considerations, and of the structures of calcium complexes (L. and W. 1982 a, b). The discussion was made in the light of a detailed knowledge of model, sm作者: VICT 時(shí)間: 2025-3-22 01:04 作者: 不愛(ài)防注射 時(shí)間: 2025-3-22 06:02
Marc K. Peter,Martina Dalla Vecchia membrane-bound exchange proteins and ATP-driven pump proteins are responsible for excreting the Ca. into the extracellular environment or into intracellular organelles that function as calcium stores. Taken together, these proteins produce a 10 000-fold gradient of Ca. over the plasma membrane, thu作者: 癡呆 時(shí)間: 2025-3-22 11:17
Frictionless Commerce und Seamless Paymentts function, is among the most fascinating. Although our knowledge of the necessity of calcium for cardiac contraction goes back to the year 1883 in which Sydney Ringer published his famous paper, the concept of voltage-sensitive calcium entry did not start until 1953. Based on the pioneering work o作者: 厚顏無(wú)恥 時(shí)間: 2025-3-22 16:45 作者: 厚顏無(wú)恥 時(shí)間: 2025-3-22 18:59 作者: 鬧劇 時(shí)間: 2025-3-22 21:24
Pascal D. K?nig,Sebastian J?ckle We have reviewed mainly the literature files in our laboratory, concentrating on papers published in 1983, 1984, and 1985. There are a number of reviews in related areas, including calmodulin (CaM) (T. et al. 1984) and its drug interaction (V. 1981; W. et al. 1985; R. et al. 1983; R. 1985), regulat作者: BOGUS 時(shí)間: 2025-3-23 01:46
Neue Trends in den Sozialwissenschaftenolved by which to accomplish this task. These mechanisms typically act together to maintain Ca. homeostasis, thereby preventing buildup of cytoplasmic Ca. which would be cytotoxic. There are two plasmalemmal active transport systems which directly regulate Ca. fluxes in many types of cells. The firs作者: placebo 時(shí)間: 2025-3-23 08:39
https://doi.org/10.1007/978-3-322-99733-3ndrial metabolism and on the adverse effects of increased Ca. load on mitochondrial function. Until quite recently, it was generally believed that the function of mitochondria in cellular Ca. metabolism was to provide a sink for Ca.. This view arose principally from the relatively low affinity of th作者: 記憶 時(shí)間: 2025-3-23 13:17 作者: forbid 時(shí)間: 2025-3-23 14:41
https://doi.org/10.1007/978-3-642-46961-9he original report of control and prevention of mania by Li. salts (C. 1949) initiated widespread use of Li. for this illness. Since Li. is most effective in reducing the mood swings of bipolar manic-depressive patients, patients suffering from this disease often take Li. for the rest of their lives作者: inhumane 時(shí)間: 2025-3-23 19:40 作者: commonsense 時(shí)間: 2025-3-24 02:14
,Die neue Sicht — Anst??e und Begründungen,d clinical investigations for some time, and some of them have been developed into useful therapeutic drugs for the treatment of hypertension and coronary disorders (F. 1977; . 1981). However, most of these studies were performed with classical pharmacologic techniques involving measurement of muscl作者: 珊瑚 時(shí)間: 2025-3-24 04:49 作者: Rheumatologist 時(shí)間: 2025-3-24 07:40
W. Heller,D. Hoffmann,H. Junger,H. Vontinery few processes that the precise location of the calcium-sensitive effector has been identified. Two examples stand out. In skeletal muscle it is known beyond doubt that calcium interacts with troponin C, a satellite protein of the actomyosin, and through the consequent activation of myosin ATPase作者: 愉快么 時(shí)間: 2025-3-24 12:36
https://doi.org/10.1007/978-3-662-25270-3philic secretion products (e.g., proteins, peptides, classical neurotransmitters, such as amines, acetylcholine, and amino acids) and to discharge these products by a process known as exocytosis. The term exocytosis was originally proposed to describe the release in bulk of the contents of a membran作者: myelography 時(shí)間: 2025-3-24 18:29
https://doi.org/10.1007/978-3-642-71806-9ATP; ATPase; Calcium; bone; lead; metabolism; proteins; smooth muscle作者: SLUMP 時(shí)間: 2025-3-24 19:33
978-3-642-71808-3Springer-Verlag Berlin Heidelberg 1988作者: misshapen 時(shí)間: 2025-3-24 23:51
Calcium in Drug Actions978-3-642-71806-9Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: 大喘氣 時(shí)間: 2025-3-25 05:30 作者: 步兵 時(shí)間: 2025-3-25 10:24
https://doi.org/10.1007/978-3-7908-1922-9The discovery of troponin (TN) in 1965, the first Ca receptor protein, provided a firm basis for the Ca concept in muscle. The subsequent discovery of calmodulin (CaM) around 1970 emancipated Ca. from muscle. Now Ca. is the common interest of all biological scientists.作者: Virtues 時(shí)間: 2025-3-25 15:37 作者: capsule 時(shí)間: 2025-3-25 16:06
,Die neue Sicht — Anst??e und Begründungen,e contractions and tension. It was not until the early 1980s that the drugs acting on calcium channels became a subject of modern electrophysiologic investigations using voltage-clamp techniques (. and . 1981, 1983; . 1983; . and . 1986; . 1983; . and . 1984; . and . 1985; . and . 1983 a, 1985; . and . 1986).作者: Memorial 時(shí)間: 2025-3-25 21:13
,Die neue Sicht — Anst??e und Begründungen,quence of events accounted for the external Ca dependence (. 1969; . 1972; . et al. 1981; . and . 1983 a, b). Moreover, the modulation of synaptic transmission, and related fundamental aspects of transmitter release associated with memory and learning, are all profoundly influenced by Ca.作者: 注意 時(shí)間: 2025-3-26 03:48
Troponin C and Calmodulin as Calcium Receptors: Mode of Action and Sensitivity to DrugsThe discovery of troponin (TN) in 1965, the first Ca receptor protein, provided a firm basis for the Ca concept in muscle. The subsequent discovery of calmodulin (CaM) around 1970 emancipated Ca. from muscle. Now Ca. is the common interest of all biological scientists.作者: Ringworm 時(shí)間: 2025-3-26 07:12
Calcium Channels as Drug Receptorsf H. and H. (1952) on the role of the sodium channel in the propagation of excitation, the existence of calcium channels was hinted at by F. and K. (1953) who investigated the electrical properties of crustacean muscle.作者: alleviate 時(shí)間: 2025-3-26 08:58
Drugs Acting on Calcium Channelse contractions and tension. It was not until the early 1980s that the drugs acting on calcium channels became a subject of modern electrophysiologic investigations using voltage-clamp techniques (. and . 1981, 1983; . 1983; . and . 1986; . 1983; . and . 1984; . and . 1985; . and . 1983 a, 1985; . and . 1986).作者: cunning 時(shí)間: 2025-3-26 15:34 作者: Acclaim 時(shí)間: 2025-3-26 19:07
0171-2004 th of Professor Peter Baker. Aware of his international recognition as an expert on the ubiquitous role of calcium in physiological processes and their pharma- cological control, the Board was gratified when Professor Baker accepted its invitation to edit a new Handbook volume on "Calcium in Drug Ac作者: IRK 時(shí)間: 2025-3-26 22:58
https://doi.org/10.1007/978-3-322-99733-3xanthines popularly used, caffeine, theobromine, theophylline and paraxanthine have a common chemical structure consisting of a double ring where a pyramidine and an imidazole combine to give the xanthine structure (Fig. 1 a). Ryanodine is a more complex molecule, incorporating a single nitrogen-containing pyrrole ring (Fig. 1 b).作者: Graphite 時(shí)間: 2025-3-27 03:39
Neue Unternehmen in Ostdeutschlandprocess utilized croton oil. Today phorbol esters isolated from croton oil as its active components, as well as synthetic analogs with a range of tumor-promoting activity are used for studies of the mechanism of tumor promotion.作者: 熄滅 時(shí)間: 2025-3-27 05:56
Pharmacology of Calcium Uptake and Release from the Sarcoplasmic Reticulum: Sensitivity to Methylxanxanthines popularly used, caffeine, theobromine, theophylline and paraxanthine have a common chemical structure consisting of a double ring where a pyramidine and an imidazole combine to give the xanthine structure (Fig. 1 a). Ryanodine is a more complex molecule, incorporating a single nitrogen-containing pyrrole ring (Fig. 1 b).作者: 格子架 時(shí)間: 2025-3-27 10:44
Phorbol Esters and Protein Kinase Cprocess utilized croton oil. Today phorbol esters isolated from croton oil as its active components, as well as synthetic analogs with a range of tumor-promoting activity are used for studies of the mechanism of tumor promotion.作者: Mercurial 時(shí)間: 2025-3-27 16:38
Die ,sche Algebra. Anwendungen,, Mg. and ligand concentrations. Inevitably we shall be looking at large protein ligands for much of the account, but we shall refer to data on small ligands from time to time. This reflects new and growing knowledge of the precise nature of calcium binding to large molecules of direct biological interest.作者: 咒語(yǔ) 時(shí)間: 2025-3-27 20:12 作者: 異端 時(shí)間: 2025-3-28 01:20 作者: RALES 時(shí)間: 2025-3-28 02:10
Chemical Factors Determining the Affinity of a Receptor for Calcium, Mg. and ligand concentrations. Inevitably we shall be looking at large protein ligands for much of the account, but we shall refer to data on small ligands from time to time. This reflects new and growing knowledge of the precise nature of calcium binding to large molecules of direct biological interest.作者: anniversary 時(shí)間: 2025-3-28 10:00 作者: 豪華 時(shí)間: 2025-3-28 13:30
Effect of Lithium in Stimulus — Response Coupling Li. modulates central nervous activity by influencing receptor-mediated phosphoinositide metabolism — and consequently also Ca. mobilization and control of Ca.-dependent neurosecretion (. et al. 1982).作者: alcoholism 時(shí)間: 2025-3-28 16:29
Pascal D. K?nig,Sebastian J?ckle 1985) and Ca. transport (C. 1984 a, b, c, d, 1985; S. 1983, 1985). Because relatively more is known about the Ca. pump in human red blood cells (RBCs) than in other types and species of cells, most of our concern has been with this type of cell. Ca. transport in the heart has been reviewed by L. (1984) and C. (1985).作者: 緊張過(guò)度 時(shí)間: 2025-3-28 19:34
Drug Effects on Plasma Membrane Calcium Transport 1985) and Ca. transport (C. 1984 a, b, c, d, 1985; S. 1983, 1985). Because relatively more is known about the Ca. pump in human red blood cells (RBCs) than in other types and species of cells, most of our concern has been with this type of cell. Ca. transport in the heart has been reviewed by L. (1984) and C. (1985).作者: 蛤肉 時(shí)間: 2025-3-28 23:37 作者: 異教徒 時(shí)間: 2025-3-29 06:30 作者: 羊齒 時(shí)間: 2025-3-29 08:36
Ligand-Binding Sites on Calmodulin 10.. (R. 1983). This situation is schematically depicted in Fig. 1. As a second step, the transient increase in intracellular Ca. needs to be translated into metabolic or contractile responses. To this end, nature has deployed a unique class of calcium-binding proteins. Upon binding Ca. they underg作者: 暗指 時(shí)間: 2025-3-29 14:31 作者: 傾聽(tīng) 時(shí)間: 2025-3-29 18:40
The Apamin-Sensitive Ca2+-Dependent K+ Channel: Molecular Properties, Differentiation, Involvement it (C. and M. 1977; G. et al. 1978). This approach has confirmed that the active site of apamin comprises the two residues Arg-13 and Arg-14. The exact three-dimensional structure of the toxin remains unknown. However, recent solution analysis of apamin by NMR techniques has suggested that the toxin 作者: Dorsal-Kyphosis 時(shí)間: 2025-3-29 21:49 作者: Feedback 時(shí)間: 2025-3-30 02:31 作者: 武器 時(shí)間: 2025-3-30 07:56 作者: 矛盾心理 時(shí)間: 2025-3-30 10:58 作者: CHYME 時(shí)間: 2025-3-30 13:00
https://doi.org/10.1007/978-3-662-41505-4er pointed out that most cells would accumulate calcium if this was dependent only upon the Donnan ratio. Further with intracellular potentials of around — 60 mV and an external calcium concentration of 1–10 m., intracellular concentrations of 0.1–1.0 . could be expected. Clearly this was not the ca作者: 調(diào)整 時(shí)間: 2025-3-30 19:32 作者: FOIL 時(shí)間: 2025-3-30 21:51
Rolf Dornberger,Dino Schwafertstionally, the recent discovery of compounds closely related in structure to the 1,4-dihydro-pyridine, nifedipine, but which serve as Ca. channel activators (Fig. 2) serves to suggest that major new categories of uses ranging from inotropy to secretory stimulation may become available in the future.作者: 推遲 時(shí)間: 2025-3-31 01:36
Pascal D. K?nig,Sebastian J?cklet (C. and M. 1977; G. et al. 1978). This approach has confirmed that the active site of apamin comprises the two residues Arg-13 and Arg-14. The exact three-dimensional structure of the toxin remains unknown. However, recent solution analysis of apamin by NMR techniques has suggested that the toxin 作者: macrophage 時(shí)間: 2025-3-31 08:31
https://doi.org/10.1007/978-3-322-99733-3evels according to the regulatory requirements of oxidative metabolism. The capacity for Ca. accumulation is also constrained by the tolerance of mitochondrial function to increased Ca. load. It is important to stress that there are therefore two aspects to the behaviour of mitochondria with respect作者: muffler 時(shí)間: 2025-3-31 10:21 作者: 證實(shí) 時(shí)間: 2025-3-31 15:03
https://doi.org/10.1007/978-3-662-25270-3e term exocytosis has expanded to include not only the release, but also the preceding fusion-fission steps. Such an extended meaning is used throughout this chapter (. 1975; . and . 1980 a; . and . 1981).作者: cartilage 時(shí)間: 2025-3-31 21:30
0171-2004 ts grateful appreciation for the admirable way in which Professor Baker took on and carried out the additional work of bringing this fine book into existence; a978-3-642-71808-3978-3-642-71806-9Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: Mammal 時(shí)間: 2025-4-1 00:42 作者: triptans 時(shí)間: 2025-4-1 03:15
Chemical Factors Determining the Affinity of a Receptor for Calciumrs on the topic have described a detailed examination of the energetics of calcium-ligand interactions, including both thermodynamic and kinetic considerations, and of the structures of calcium complexes (L. and W. 1982 a, b). The discussion was made in the light of a detailed knowledge of model, sm
