標題: Titlebook: Calcium Entry Pathways in Non-excitable Cells; Juan A. Rosado Book 2016 The Editor(s) (if applicable) and The Author(s), under exclusive l [打印本頁] 作者: 柳條筐 時間: 2025-3-21 19:45
書目名稱Calcium Entry Pathways in Non-excitable Cells影響因子(影響力)
書目名稱Calcium Entry Pathways in Non-excitable Cells影響因子(影響力)學(xué)科排名
書目名稱Calcium Entry Pathways in Non-excitable Cells網(wǎng)絡(luò)公開度
書目名稱Calcium Entry Pathways in Non-excitable Cells網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Calcium Entry Pathways in Non-excitable Cells被引頻次
書目名稱Calcium Entry Pathways in Non-excitable Cells被引頻次學(xué)科排名
書目名稱Calcium Entry Pathways in Non-excitable Cells年度引用
書目名稱Calcium Entry Pathways in Non-excitable Cells年度引用學(xué)科排名
書目名稱Calcium Entry Pathways in Non-excitable Cells讀者反饋
書目名稱Calcium Entry Pathways in Non-excitable Cells讀者反饋學(xué)科排名
作者: Ledger 時間: 2025-3-21 21:43 作者: 吃掉 時間: 2025-3-22 03:07
The TRPCs, Orais and STIMs in ER/PM Junctionsained by Ca. influx across the plasma membrane through the Orai and TRPC channels. These Ca. influx channels form complexes at ER/PM junctions with the ER Ca. sensor STIM1, which activates the channels. The function of STIM1 is modulated by other STIM isoforms like STIM1L, STIM2 and STIM2.1/STIM2β a作者: 欺騙手段 時間: 2025-3-22 05:13 作者: 預(yù)定 時間: 2025-3-22 09:09
Role of TRPC Channels in Store-Operated Calcium Entryreticulum (ER) and contributes to the control of various physiological functions in a wide variety of cell types. The transient receptor potential canonical (TRPC) channels (TRPCs 1–7), that are activated by stimuli leading to PIP. hydrolysis, were first identified as molecular components of SOCE ch作者: Asseverate 時間: 2025-3-22 15:41 作者: Asseverate 時間: 2025-3-22 19:49
Extracellular Calcium Has Multiple Targets to Control Cell Proliferationeans by which extracellular calcium can signal to cells and regulate many cellular processes including cell proliferation, migration and invasion of tumoral cells. Many intracellular signaling pathways are sensitive to cytosolic calcium rises and conversely intracellular signaling pathways can modul作者: echnic 時間: 2025-3-22 23:19
Regulation of Platelet Function by Orai, STIM and TRPd Ca. signals is store-operated Ca. entry (SOCE), where the Ca. sensor STIM1 and the channels of the Orai family, as well as TRPC members are the key elements. STIM1-dependent SOCE plays a major role in collagen-stimulated Ca. signaling, phosphatidylserine exposure and thrombin generation. Furthermo作者: cunning 時間: 2025-3-23 04:48 作者: 公司 時間: 2025-3-23 08:16 作者: 手榴彈 時間: 2025-3-23 10:02
Transient Receptor Potential Canonical 7 (TRPC7), a Calcium (Ca2+) Permeable Non-selective Cation Chctive cation channels. The gene encoding the TRPC7 channel plasma membrane protein was first cloned from mouse brain. TRPC7 mRNA and protein have been detected in cell types derived from multiple organ systems from various species including humans. G.-coupled protein receptor activation is the predo作者: Apraxia 時間: 2025-3-23 16:07 作者: CHOKE 時間: 2025-3-23 18:01 作者: 沙文主義 時間: 2025-3-23 22:54
The Calcium Entry-Calcium Refilling Couplinging between Ca. entry and Ca. refilling is playing a central role in this Ca. homeostasis. Since the capacitative Ca. entry has been described, different mechanisms have been proposed in order to explain how the Ca. entry could be under control of intracellular store Ca. depletion. Today, in additio作者: 熒光 時間: 2025-3-24 02:38
Microdomains Associated to Lipid Raftse affected in several pathologies including cancer. The basic molecular constituents of SOCE are Orai, the pore forming unit, and STIM, a multidomain protein with at least two principal functions: one is to sense the Ca. content inside the lumen of the endoplasmic reticulum(ER) and the second is to 作者: 哄騙 時間: 2025-3-24 10:06 作者: Nebulizer 時間: 2025-3-24 14:03 作者: Exploit 時間: 2025-3-24 15:41 作者: Robust 時間: 2025-3-24 19:06
Phospholipase A2 as a Molecular Determinant of Store-Operated Calcium Entrywere suggested as agonists of store operated calcium channels (SOCC) and other TRP channels. Herein, we will review the important role of iPLA. on the intracellular Ca. handling focusing on its role in SOCE regulation and its implication in physiological and/or pathological processes.作者: 即席演說 時間: 2025-3-25 00:32
0065-2598 ritical analysis of the current observations and directions Calcium entry pathways in non-excitable cells presents a concise synthesis of thoughtfully selected topics covering from the different calcium entry mechanisms in non-excitable cells to the cellular microdomains and organelles regulating th作者: Humble 時間: 2025-3-25 06:53
Neue Entwicklungen in der Dermatologiee TRPC channels, the Orai channels and the STIMs, their key interacting proteins and how interaction of the STIMs with the channels gates their activity. The chapter closes by highlighting open questions and potential future directions in this field.作者: Irritate 時間: 2025-3-25 09:20 作者: 壓艙物 時間: 2025-3-25 15:12
Neue Entwicklungen in der DermatologieTRPC6 expression might lead to thrombosis in humans. The role of STIM1, Orai1 and TRPCs, and thus SOCE, in thrombus formation, suggests that therapies directed against SOCE and targeting these molecules during cardiovascular and cerebrovascular events could significantly improve traditional anti-thrombotic treatments.作者: 繁殖 時間: 2025-3-25 19:15
Percy Lehmann,S. Helbig,E. H?lzle,G. Plewighe regulation of various cellular functions however, the depth of our understanding of TRPC7 channel function and regulation is limited in comparison to other TRP channel family members. This review takes a historical look at our current knowledge of TRPC7 mechanisms of activation and its role in cellular physiology and pathophysiology.作者: 蘆筍 時間: 2025-3-25 23:48 作者: 感染 時間: 2025-3-26 04:10
The TRPCs, Orais and STIMs in ER/PM Junctionse TRPC channels, the Orai channels and the STIMs, their key interacting proteins and how interaction of the STIMs with the channels gates their activity. The chapter closes by highlighting open questions and potential future directions in this field.作者: 朝圣者 時間: 2025-3-26 05:40
TRP-Na+/Ca2+ Exchanger Couplinglls. In particular we focus on the potential role of nanojunctions, where the close apposition of plasma and intracellular membranes may help create the conditions needed for the generation of localised rises in Na. concentration that would be required to trigger reverse mode exchange.作者: Adj異類的 時間: 2025-3-26 12:22 作者: 松緊帶 時間: 2025-3-26 14:15 作者: VEST 時間: 2025-3-26 18:39 作者: Flirtatious 時間: 2025-3-26 21:14
Historical Overview of Store-Operated Ca2+ Entryl members of the TRPC family of channels also take part of the SOC macromolecular complex. This introductory chapter summarizes the early pieces of evidence that led to the concept of SOCE and the components of the store-operated signaling pathway.作者: palette 時間: 2025-3-27 04:47
The STIM1: Orai Interactionn the plasmamembrane. The identification of STIM1 and Orai1 and recently the structural resolution of both proteins by X-ray crystallography and nuclear magnetic resonance substantiated many findings from structure-function studies which has substantially improved the understanding of CRAC channel a作者: 冰河期 時間: 2025-3-27 06:34 作者: MIRE 時間: 2025-3-27 09:44
Extracellular Calcium Has Multiple Targets to Control Cell Proliferationas for metabotropic receptors, they not only modulate calcium channel expression but they may also control calcium-dependent K+ channels. The multiplicity of intracellular signaling pathways involved, their sensitivity to local and global intracellular calcium increase and to CaSR and GPRC6a stimula作者: Defiance 時間: 2025-3-27 15:54
On the Roles of the Transient Receptor Potential Canonical 3 (TRPC3) Channel in Endothelium and MacrPC3 functions to atherogenesis has recently began to receive validation through studies in mouse models of atherosclerosis with conditional gain or loss of TRPC3 function. This chapter summarizes these novel findings and provides a discussion of their impact in the context of atherosclerosis, in an 作者: Narcissist 時間: 2025-3-27 19:11 作者: ARK 時間: 2025-3-28 00:43
Calcium Entry Through Thermosensory Channelsole of Ca. fluxes induced by thermoTRPs on the dynamics of membrane-attached signalling complexes as well as their significance in cellular processes, are central issues that will expand the opportunities for therapeutic intervention in disorders involving dysfunction of thermoTRP channels.作者: Morose 時間: 2025-3-28 04:05 作者: Intellectual 時間: 2025-3-28 07:13
The Calcium Entry-Calcium Refilling Couplingertaking the whole cell. The coupling between Ca. entry and Ca. refilling can possibly act much further away from the plasma membrane. Ca., uptaken by SERCAs, have been described to move faster and further in the ER than in the cytosol and to create specific signal that depends on Ca. entry but at l作者: Indicative 時間: 2025-3-28 10:52
Role of Scaffolding Proteins in the Regulation of TRPC-Dependent Calcium Entry building of signaling complexes. The scaffolding proteins are involved in the assembling of these Ca. signaling complexes, the correct sub-cellular localization of protein partners, and the regulation of the TRPC channelosome. In particular, these proteins, via their multiple protein–protein intera作者: FIR 時間: 2025-3-28 16:35
Gerd Witt,Andreas Wegner,Jan Sehrtl members of the TRPC family of channels also take part of the SOC macromolecular complex. This introductory chapter summarizes the early pieces of evidence that led to the concept of SOCE and the components of the store-operated signaling pathway.作者: transient-pain 時間: 2025-3-28 20:17
Gerd Witt,Janick Ambrosy,Fabian Neugebauern the plasmamembrane. The identification of STIM1 and Orai1 and recently the structural resolution of both proteins by X-ray crystallography and nuclear magnetic resonance substantiated many findings from structure-function studies which has substantially improved the understanding of CRAC channel a作者: GROUP 時間: 2025-3-29 02:33
Neue Entwicklungen in der Dermatologieminus. Intriguingly, TRPC1 function is not only dependent on STIM1 but also requires Orai1. The critical functional interaction between TRPC1 and Orai1, which determines the activation of TRPC1, has also been identified. In this review, we will discuss current concepts regarding the role of TRPC cha作者: FEMUR 時間: 2025-3-29 05:12 作者: 尾隨 時間: 2025-3-29 07:40
J. Hunyadi,M. Simon Jr.,O. P. HornsteinPC3 functions to atherogenesis has recently began to receive validation through studies in mouse models of atherosclerosis with conditional gain or loss of TRPC3 function. This chapter summarizes these novel findings and provides a discussion of their impact in the context of atherosclerosis, in an 作者: 解開 時間: 2025-3-29 13:28 作者: NIP 時間: 2025-3-29 19:17 作者: –FER 時間: 2025-3-29 20:19
Die Hexachlorbenzol (HCB)-Porphyrie,ilization via a range of routes such as amplification of G-protein-coupled receptor-dependent Ca. responses. This chapter also considers the mechanism by which cells generate extracellular ATP for autocrine or paracrine activation of P2X1 receptors. For example cytosolic ATP efflux can result from o作者: JAMB 時間: 2025-3-30 02:43 作者: sacrum 時間: 2025-3-30 04:50
O. P. Hornstein,U. W. Schnyder,J. Sch?nfeld building of signaling complexes. The scaffolding proteins are involved in the assembling of these Ca. signaling complexes, the correct sub-cellular localization of protein partners, and the regulation of the TRPC channelosome. In particular, these proteins, via their multiple protein–protein intera作者: 痛得哭了 時間: 2025-3-30 08:35
0065-2598 channelsas the calcium-permeable channels located in the plasma membrane. The location, interactions and function of these channels are finely regulated by a number of scaffolding proteins, membrane microdomai978-3-319-80050-9978-3-319-26974-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: Parallel 時間: 2025-3-30 15:59 作者: 債務(wù) 時間: 2025-3-30 16:48 作者: anatomical 時間: 2025-3-30 20:51 作者: murmur 時間: 2025-3-31 03:24
Juan A. RosadoProvides an extensive overview of the mechanisms underlying calcium entry in non-excitable cells.Includes relevant background information, critical analysis of the current observations and directions 作者: forestry 時間: 2025-3-31 07:36
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/c/image/220772.jpg作者: DOLT 時間: 2025-3-31 10:23
Calcium Entry Pathways in Non-excitable Cells978-3-319-26974-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 送秋波 時間: 2025-3-31 16:25
Gerd Witt,Andreas Wegner,Jan Sehrtctivation of phospholipase C by occupation of G protein-coupled receptors leads to the generation of inositol 1,4,5-trisphosphate (IP.) and diacylglycerol (DAG), which, in turn, initiate two Ca. entry pathways: Ca. release from intracellular Ca. stores, signaled by IP., leads to the activation of st
