標題: Titlebook: Buruli Ulcer; Mycobacterium Ulcera Gerd Pluschke,Katharina R?ltgen Book‘‘‘‘‘‘‘‘ 2019 The Editor(s) (if applicable) and The Author(s) 2019 C [打印本頁] 作者: T-Lymphocyte 時間: 2025-3-21 17:56
書目名稱Buruli Ulcer影響因子(影響力)
書目名稱Buruli Ulcer影響因子(影響力)學科排名
書目名稱Buruli Ulcer網(wǎng)絡公開度
書目名稱Buruli Ulcer網(wǎng)絡公開度學科排名
書目名稱Buruli Ulcer被引頻次
書目名稱Buruli Ulcer被引頻次學科排名
書目名稱Buruli Ulcer年度引用
書目名稱Buruli Ulcer年度引用學科排名
書目名稱Buruli Ulcer讀者反饋
書目名稱Buruli Ulcer讀者反饋學科排名
作者: Consequence 時間: 2025-3-21 20:56 作者: Psa617 時間: 2025-3-22 01:24
Luis J. Alías,Paolo Mastrolia,Marco Rigolievidence, including epidemiological and genetic studies. This holistic approach is expected to shed further light on the intriguing pathophysiology of this disease and help guide future research efforts.作者: 擺動 時間: 2025-3-22 07:16 作者: FRET 時間: 2025-3-22 11:33 作者: 單挑 時間: 2025-3-22 16:03 作者: 結(jié)果 時間: 2025-3-22 18:38
Thermotherapy of Buruli Ulcer,n be applied in early, undifferentiated stages of disease without causing harm and with the benefit of preventing advancement into severe complicated disease. Thermotherapy is highly effective, easy to apply, cheap, well tolerated, free of relevant adverse effects and has nonspecific positive effects on wound healing.作者: canonical 時間: 2025-3-22 21:33 作者: inflate 時間: 2025-3-23 03:53
of Buruli ulcer in different geographic regions.Reviews exha.A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insi作者: intricacy 時間: 2025-3-23 08:46
P. P. B. Eggermont,V. N. LaRicciaderreported in most of the continent; or the specific environmental conditions in French Guiana represent a unique niche for the disease to appear; or a sublineage of . has established in French Guiana that has a higher virulence than other members of the ancestral lineage found in the Americas.作者: intellect 時間: 2025-3-23 13:04
Infection in French Guiana; Current State of Knowledge,derreported in most of the continent; or the specific environmental conditions in French Guiana represent a unique niche for the disease to appear; or a sublineage of . has established in French Guiana that has a higher virulence than other members of the ancestral lineage found in the Americas.作者: 未完成 時間: 2025-3-23 14:17
Book‘‘‘‘‘‘‘‘ 2019nt of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of .Mycobacterium ulcerans..作者: MEN 時間: 2025-3-23 20:02
P. P. B. Eggermont,V. N. LaRicciaycolactones, led to a specific lineage of . causing the majority of human disease. At local scales, detailed longitudinal, comparative genomic studies of . isolates recovered from BU endemic regions have revealed patterns of pathogen spread that are providing useful new understandings around BU transmission.作者: 迅速飛過 時間: 2025-3-23 23:52
Book‘‘‘‘‘‘‘‘ 2019 in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the micr作者: MAIM 時間: 2025-3-24 04:36 作者: linear 時間: 2025-3-24 07:00 作者: Hyperopia 時間: 2025-3-24 12:45 作者: figurine 時間: 2025-3-24 15:22 作者: 啤酒 時間: 2025-3-24 21:09
Buruli Ulcer in Japan,ue to Japan and potentially China. Genetic characterization of this species has begun, and the efficacy of various therapies has been analyzed. Although treatment with triple antimicrobial therapy comprising rifampicin (RFP; 450?mg/day), levofloxacin (LVFX; 500?mg/day), and clarithromycin (CAM; 800?作者: GEON 時間: 2025-3-25 01:13
Population Genomics and Molecular Epidemiology of ,and in particular within Africa and Australia, the regions most affected by Buruli ulcer (BU). This chapter summarizes our current understanding of the emergence of . from a . ancestor, and describes how at least two evolutionary bottlenecks, that included acquiring the specific capability to make m作者: 遠足 時間: 2025-3-25 07:00 作者: 避開 時間: 2025-3-25 08:28
The Immunology of Buruli Ulcer,rotic toxin that has shown the ability to interfere with the immune response. This poses an additional difficulty to the understanding of the immunological determinants for the outcome of infection, a fundamental step to develop better preventive or curative strategies. In this chapter, the immune r作者: obnoxious 時間: 2025-3-25 12:25
Buruli Ulcer in Animals and Experimental Infection Models,y occur mainly at places where no or only sparse fur is present: the ears, paws and the nose. To date such naturally infected animals have only been detected in Australia. In order to tackle specific research questions in vivo, several experimental . infection animal models have been developed, of w作者: 堅毅 時間: 2025-3-25 16:54
Laboratory Diagnosis of Buruli Ulcer: Challenges and Future Perspectives,ve agent,?., is incomplete. Early case detection and rapid initiation of treatment are key elements to prevent the development of large, disfiguring ulcers often associated with permanent physical disability and stigma. BU has been reported from 34 countries, with the greatest disease burden in West作者: 撤退 時間: 2025-3-25 21:41
Antimicrobial Treatment of , Infection,s in their patients to be caused by tuberculosis or leprosy, when they observed numerous acid-fast bacilli in the biopsy specimens [1]. The typical duration of illness was between 1 and 2?years; treatment was essentially surgical. With the advent of chemotherapy for tuberculosis [2–4], and later for作者: quiet-sleep 時間: 2025-3-26 01:30 作者: collagen 時間: 2025-3-26 06:57 作者: Exhilarate 時間: 2025-3-26 10:35 作者: temperate 時間: 2025-3-26 16:38 作者: florid 時間: 2025-3-26 20:16
Transdisciplinary Research and Action to Stop Buruli Ulcer: A case Study from Philanthropy,e. With the goal to catalyse a transdisciplinary consortium bundling Buruli ulcer research into a consorted effort, the UBS Optimus Foundation engaged researchers from different disciplines and countries, with a prominent role of endemic countries and good links to national Buruli ulcer control?prog作者: Intervention 時間: 2025-3-26 23:47
Paul P. B. Eggermont,Vincent N. LaRiccia been reported from 34 countries, mainly with tropical and subtropical climates. Following a peak of 5954 reported BU cases globally in 2004 the number of new recorded cases has been decreasing over the past years. In 2016, a total of 1952 BU cases were reported to the World Health Organization (WHO作者: 繁殖 時間: 2025-3-27 02:12
Paul P. B. Eggermont,Vincent N. LaRicciath C?te d’Ivoire, Ghana, Benin, and Cameroon being the four most endemic countries. As the disease affects mainly populations in remote, rural areas, where access to formal healthcare structures is limited, the true prevalence of BU is difficult to gauge. The continued preference of BU patients in m作者: FRAX-tool 時間: 2025-3-27 08:45
P. P. B. Eggermont,V. N. LaRicciars affecting residents of the Bairnsdale?region in the temperate Australian state of Victoria. The disease was also recognised from the 1950s in tropical?far north?Queensland where it is called Daintree ulcer or Mossman ulcer. There are other small pockets of transmission in coastal Queensland and t作者: Bravura 時間: 2025-3-27 12:55
P. P. B. Eggermont,V. N. LaRicciathe cases of BU in America with only a few cases reported in Suriname, Peru, Mexico and Bolivia in the past [2, 3]. Either BU is underdiagnosed and underreported in most of the continent; or the specific environmental conditions in French Guiana represent a unique niche for the disease to appear; or作者: SLING 時間: 2025-3-27 13:37
P. P. B. Eggermont,V. N. LaRicciaue to Japan and potentially China. Genetic characterization of this species has begun, and the efficacy of various therapies has been analyzed. Although treatment with triple antimicrobial therapy comprising rifampicin (RFP; 450?mg/day), levofloxacin (LVFX; 500?mg/day), and clarithromycin (CAM; 800?作者: tic-douloureux 時間: 2025-3-27 19:37 作者: 使絕緣 時間: 2025-3-27 23:07 作者: 小平面 時間: 2025-3-28 03:33
Luis J. Alías,Paolo Mastrolia,Marco Rigolirotic toxin that has shown the ability to interfere with the immune response. This poses an additional difficulty to the understanding of the immunological determinants for the outcome of infection, a fundamental step to develop better preventive or curative strategies. In this chapter, the immune r作者: 暫時過來 時間: 2025-3-28 07:02
Luis J. Alías,Paolo Mastrolia,Marco Rigoliy occur mainly at places where no or only sparse fur is present: the ears, paws and the nose. To date such naturally infected animals have only been detected in Australia. In order to tackle specific research questions in vivo, several experimental . infection animal models have been developed, of w作者: 改變 時間: 2025-3-28 12:47 作者: 施舍 時間: 2025-3-28 18:21
https://doi.org/10.1007/978-1-4612-5282-5s in their patients to be caused by tuberculosis or leprosy, when they observed numerous acid-fast bacilli in the biopsy specimens [1]. The typical duration of illness was between 1 and 2?years; treatment was essentially surgical. With the advent of chemotherapy for tuberculosis [2–4], and later for作者: 南極 時間: 2025-3-28 22:04
https://doi.org/10.1007/BFb0070226ed on this success, WHO guidelines listed the application of heat as a treatment option for BU in 2000. However, the heat application devices initially employed were impractical. The phase change material (PCM) sodium acetate trihydrate, offers an ideal technical solution. Both, a proof-of-principle作者: 殺死 時間: 2025-3-28 23:13
The maximum likelihood estimator, confirmed by several studies, including a randomised controlled clinical trial (Nienhuis et al., Lancet 375:664–672, 2010). Despite successful outcomes with this treatment regimen, the healing process is still characterized by long hospital stays as a result of delayed healing, in a significant pro作者: 畏縮 時間: 2025-3-29 03:03
Tiziano Squartini,Diego Garlaschellience rates between 1 and 5% in BU endemic countries. Evidence from Benin, Cameroon, Ghana and Gabon suggest that HIV may increase the risk of BU [1–5]. For example, in the . programme in Akonolinga, Cameroon, the prevalence of HIV was approximately 3–6 times higher in BU treated patients compared to作者: Graphite 時間: 2025-3-29 10:50 作者: CESS 時間: 2025-3-29 11:29 作者: encomiast 時間: 2025-3-29 17:17
https://doi.org/10.1007/978-3-030-11114-4Chronic Skin Infection; Host-Pathogen Interaction; Mycobacterial Infection; Neglected Tropical Diseases作者: etidronate 時間: 2025-3-29 23:24
The Editor(s) (if applicable) and The Author(s) 2019作者: 平庸的人或物 時間: 2025-3-30 02:51 作者: 馬具 時間: 2025-3-30 06:19 作者: 業(yè)余愛好者 時間: 2025-3-30 09:15
Paul P. B. Eggermont,Vincent N. LaRicciahly pathogenic for humans appears to be the acquisition of a plasmid, bearing genes encoding polyketide synthases and polyketide-modifying enzymes involved in the biosynthesis of a unique macrolide toxin, named mycolactone. The cytotoxic and immunosuppressive properties of mycolactone account for mu作者: Estrogen 時間: 2025-3-30 12:43 作者: Delude 時間: 2025-3-30 20:06
P. P. B. Eggermont,V. N. LaRicciacal possum population and then spills over to humans living nearby. Biting insects, particularly mosquitoes, are likely mechanical vectors but there may be other pathways of transmission involved. Universal?access to rapid diagnosis with PCR and availability of combination oral antibiotic therapy an作者: 褪色 時間: 2025-3-30 23:01
P. P. B. Eggermont,V. N. LaRicciation in the occurrence of BU and possibly of the number of bacteria in the environment. Therefore, although there are not many cases of BU in Japan, studying them will shed light on the bacteriological and clinical aspects of BU.作者: PANEL 時間: 2025-3-31 01:18
https://doi.org/10.1007/978-1-0716-1244-6and B [6, 7] (Fig. 1). Since the initial discovery of mycolactone A/B, eight additional mycolactone congeners have been identified that are either produced by . strains of different geographical origins or genetically related fish and frog pathogens, which were initially given different species desi作者: 血友病 時間: 2025-3-31 08:23
Luis J. Alías,Paolo Mastrolia,Marco Rigoliew antimicrobial compounds or vaccine candidates for BU. The histopathological appearance of the lesions and the spreading of the bacteria to the lymph nodes, however, are quite different to what is observed in the human disease. In order to overcome these disadvantages, the pig as a model for BU wa作者: 出沒 時間: 2025-3-31 09:40
https://doi.org/10.1007/978-1-4612-5282-5ar appearance is high. With the introduction of combination antibiotic therapy, replacing excision surgery as the standard treatment for BU, pre-treatment confirmation of the clinical diagnosis has further gained in importance to avoid the redundant use of anti-mycobacterial drugs. At present, avail
