作者: 遵循的規(guī)范 時(shí)間: 2025-3-21 22:49 作者: 事與愿違 時(shí)間: 2025-3-22 03:35 作者: 內(nèi)疚 時(shí)間: 2025-3-22 06:55 作者: 疲憊的老馬 時(shí)間: 2025-3-22 11:50
Technical and Comparative Aspects of Brain Glycogen Metabolism,n. This uncertainty stems in part from several technical challenges inherent in the study of brain glycogen metabolism, and may also stem from some conceptual limitations. Factors presenting technical challenges include low glycogen content in brain, non-homogenous labeling of glycogen by radiotrace作者: 遭遇 時(shí)間: 2025-3-22 15:03 作者: stress-response 時(shí)間: 2025-3-22 19:03
Glycogenolysis in Cerebral Cortex During Sensory Stimulation, Acute Hypoglycemia, and Exercise: Impd memory consolidation, is strongly supported by many studies. However, specific mechanisms through which glycogen sustains essential functions remain to be established by rigorous, quantitative studies. Cerebral cortical glycogen concentrations are in the range of 10–12 μmol/g in carefully-handled 作者: overreach 時(shí)間: 2025-3-22 22:37
State-Dependent Changes in Brain Glycogen Metabolism,. These molecular and metabolic features are under the control of neuronal activity through the interdependent action of neuromodulatory tone, ionic homeostasis and availability of metabolic substrates, all variables that concur to define the state of the system. In this chapter, we briefly describe作者: 蝕刻術(shù) 時(shí)間: 2025-3-23 04:38
Glycogen in Astrocytes and Neurons: Physiological and Pathological Aspects, in brain function. In this regard, genetically modified animals have allowed researchers to unravel new roles of this polysaccharide in the brain. Remarkably, mice in which glycogen synthase is abolished in the brain, and thus devoid of brain glycogen, are viable, thereby indicating that the polysa作者: 陳腐思想 時(shí)間: 2025-3-23 09:09 作者: Hippocampus 時(shí)間: 2025-3-23 11:55 作者: Hirsutism 時(shí)間: 2025-3-23 15:28 作者: Cubicle 時(shí)間: 2025-3-23 20:26
Development of a Model to Test Whether Glycogenolysis Can Support Astrocytic Energy Demands of Na+,uding findings of much higher than previously recognized concentrations, consumption at substantial rates compared with utilization of blood-borne glucose, and involvement in ion pumping and in neurotransmission and memory. However, it remains unclear how glycogenolysis is coupled to neuronal activi作者: amyloid 時(shí)間: 2025-3-23 23:50
2190-5215 n is also directly implicated in abnormal neuronal excitability and mental retardation that characterize brain disorders like Lafora disease and Pompe disease.??.978-3-030-27482-5978-3-030-27480-1Series ISSN 2190-5215 Series E-ISSN 2190-5223 作者: Harness 時(shí)間: 2025-3-24 05:18 作者: 環(huán)形 時(shí)間: 2025-3-24 07:38
Regional Distribution of Glycogen in the Mouse Brain Visualized by Immunohistochemistry,nt of glycogen distribution in the rodent brain. In this article, we describe glycogen distribution in the mouse brain using glycogen immunohistochemistry. We find heterogeneous glycogen storage patterns at multiple spatial scales. The heterogeneous glycogen distribution patterns may underlie local 作者: Anecdote 時(shí)間: 2025-3-24 14:33
Glycogenolysis in Cerebral Cortex During Sensory Stimulation, Acute Hypoglycemia, and Exercise: Impa theoretical maximum of 6 when no other substrates are metabolized) reduces OGI from 5.0 to 2.8. Thus, at least 53% of the carbohydrate is not oxidized, suggesting that glycogen mobilization supports astrocytic glycolysis, not neuronal oxidation of glycogen-derived lactate that would cause OGI to e作者: 薄荷醇 時(shí)間: 2025-3-24 16:33 作者: 極少 時(shí)間: 2025-3-24 19:49 作者: 可忽略 時(shí)間: 2025-3-25 00:14 作者: 減去 時(shí)間: 2025-3-25 05:48
Dysregulation of Glycogen Metabolism with Concomitant Spatial Memory Dysfunction in Type 2 Diabetesl mechanism responsible for memory dysfunction in type 2 diabetes, and showing for the first time that chronic exercise could be an effective therapy for type-2-diabetes-induced hippocampal memory decline.作者: 擔(dān)心 時(shí)間: 2025-3-25 10:47 作者: 最低點(diǎn) 時(shí)間: 2025-3-25 11:48 作者: 殺子女者 時(shí)間: 2025-3-25 16:31 作者: Rodent 時(shí)間: 2025-3-25 21:55 作者: Apraxia 時(shí)間: 2025-3-26 03:24 作者: ALIAS 時(shí)間: 2025-3-26 07:38
https://doi.org/10.1007/978-3-642-78980-9ged exhaustive exercise, muscle glycogen was depleted and brain glycogen decreased when associated with decreased blood glucose levels and increased serotonergic activity known as central fatigue factors, suggesting brain glycogen decrease as an integrative factor for central fatigue. Prolonged exha作者: CUMB 時(shí)間: 2025-3-26 08:54
https://doi.org/10.1007/978-3-642-87559-5ns become more vulnerable to depleted glycogen, although aging axons can use lactate as efficiently as young axons. Lactate equally supports function during aglycemia in corpus callosum (CC), which consists of a mixture of myelinated and unmyelinated axons. Moreover, axon function in CC shows greate作者: defenses 時(shí)間: 2025-3-26 13:08
https://doi.org/10.1007/978-3-642-87559-5l mechanism responsible for memory dysfunction in type 2 diabetes, and showing for the first time that chronic exercise could be an effective therapy for type-2-diabetes-induced hippocampal memory decline.作者: 火花 時(shí)間: 2025-3-26 19:13
Peter G. Elliott BSc, Mb ChB, DRCOG, MRCGPturnover of pathways that intersect with glycogen mobilization. A series of equations is developed to describe the stoichiometric relationships between net glycogen consumption that is predominantly in astrocytes with the rate of the glutamate-glutamine cycle, rates of astrocytic and neuronal glycol作者: 枯萎將要 時(shí)間: 2025-3-26 22:58 作者: 忍受 時(shí)間: 2025-3-27 04:03 作者: 狼群 時(shí)間: 2025-3-27 07:37
Book 2019 understanding of why glycogen is so critical for normal brain function. The role of glycogen in cellular neurophysiology remains largely unclear and its specific contribution to the energy demand of brain cells is still elusive.Glycogen is the sole cerebral glucose reserve and is emerging as a fund作者: Modicum 時(shí)間: 2025-3-27 13:03
Barbara Holshouser Ph.D.,Stephen Ashwal M.D.al conditions, when tissue energy demand is increased above baseline levels in the presence of normoglycemic concentrations of glucose. The signaling mechanism by which axons alert astrocytes to their increased energy requirement is likely to be elevated interstitial K., the inevitable consequence of increased neuronal activity.作者: Entreaty 時(shí)間: 2025-3-27 14:19
https://doi.org/10.1007/978-3-662-50468-0 how glycogen responds to selected behavioral, nutritional, environmental, hormonal, developmental and pathological conditions. We argue that interpreting glycogen metabolism through the lens of brain state is an effective approach to establish the relevance of energetics in connecting molecular and cellular neurophysiology to behavior.作者: SIT 時(shí)間: 2025-3-27 17:52 作者: 一再困擾 時(shí)間: 2025-3-28 01:15
https://doi.org/10.1007/978-3-642-75525-5brief overview highlights some of the major advances in elucidation of glycogen’s roles in astrocytic functions and neurotransmission and the severe consequences of aberrant neuronal glycogen metabolism.作者: NAG 時(shí)間: 2025-3-28 02:08
Major Advances in Brain Glycogen Research: Understanding of the Roles of Glycogen Have Evolved frombrief overview highlights some of the major advances in elucidation of glycogen’s roles in astrocytic functions and neurotransmission and the severe consequences of aberrant neuronal glycogen metabolism.作者: 問(wèn)到了燒瓶 時(shí)間: 2025-3-28 07:14 作者: anachronistic 時(shí)間: 2025-3-28 12:19
Optimum Procedure for the MRM Examination,sed, highlighting effects on the brain and discussing findings in genetically modified animal models that recapitulate these diseases. Finally, implications of glycogen synthesis in neurodegenerative and other diseases that impact the brain are presented.作者: 產(chǎn)生 時(shí)間: 2025-3-28 15:30
Hepatic Encephalopathy in Childrenical aspects of glycogen metabolism that limit the conditions under which glycogen metabolism can be useful or advantageous over glucose metabolism. Comparisons with glycogen metabolism in skeletal muscle provide an additional perspective on potential functions of glycogen in brain.作者: Estrogen 時(shí)間: 2025-3-28 22:39 作者: fatuity 時(shí)間: 2025-3-29 02:43 作者: 名字的誤用 時(shí)間: 2025-3-29 05:00
Mauro DiNuzzo,Arne SchousboeProvides a timely and extensive overview of current knowledge of cerebral glycogen aimed at fundamentally revisiting the vestigial nature commonly associated with this polysaccharide in the brain.Focu作者: 芳香一點(diǎn) 時(shí)間: 2025-3-29 10:30 作者: Temporal-Lobe 時(shí)間: 2025-3-29 13:18 作者: 遵循的規(guī)范 時(shí)間: 2025-3-29 17:59 作者: Intervention 時(shí)間: 2025-3-29 21:58
Optimum Procedure for the MRM Examination,actions of glycogen synthase and the glycogen branching enzyme to elongate glucose chains and introduce branch points in a growing glycogen molecule. This review focuses on the synthesis of glycogen in the brain, with an emphasis on glycogen synthase, but draws on salient studies in mammalian muscle作者: 溫室 時(shí)間: 2025-3-30 02:27