標(biāo)題: Titlebook: Brain Damage and Repair; From Molecular Resea T. Herdegen,J. Delgado-García Book 2004 Springer Science+Business Media B.V. 2004 [打印本頁] 作者: 宣告無效 時(shí)間: 2025-3-21 18:55
書目名稱Brain Damage and Repair影響因子(影響力)
書目名稱Brain Damage and Repair影響因子(影響力)學(xué)科排名
書目名稱Brain Damage and Repair網(wǎng)絡(luò)公開度
書目名稱Brain Damage and Repair網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Brain Damage and Repair被引頻次
書目名稱Brain Damage and Repair被引頻次學(xué)科排名
書目名稱Brain Damage and Repair年度引用
書目名稱Brain Damage and Repair年度引用學(xué)科排名
書目名稱Brain Damage and Repair讀者反饋
書目名稱Brain Damage and Repair讀者反饋學(xué)科排名
作者: defile 時(shí)間: 2025-3-21 22:50 作者: Amenable 時(shí)間: 2025-3-22 04:22 作者: infinite 時(shí)間: 2025-3-22 06:37
The Organelles II: Endoplasmic Reticulum and its Overloadfunctioning is impaired in multiple ways. These include disturbances of ER calcium homeostasis, impairment of ERAD and UPR, and insufficient proteasome functioning which triggers secondary ER dysfunction. Therapeutic interventions designed to suppress the pathological process culminating in neuronal作者: 鞏固 時(shí)間: 2025-3-22 12:00
Transcriptional Dysfunctions as Pathogenic Mechanism of Neurodegenerative Diseases protein diversity and determine the subcellular location, molecular interactions, or function of proteins. Neuron-specific proteins involved in RNA splicing and metabolism are affected in several neurological disorders. Defects in RNA processing proteins, such as SMN protein, may lead to the Spinal作者: malign 時(shí)間: 2025-3-22 16:58
Formation of Radicalsn’s disease increased levels of biomarkers of oxidative and nitrosative stress have been identified in the brain. Some of which such as hydroxyalkenals and isoprostanes may even gain diagnostic value for the determination of the degree of neurodegeneration. However, scientific efforts have to be con作者: Hyperalgesia 時(shí)間: 2025-3-22 17:16
Microglia and the Cerebral Defence System or disturbances in the CNS homeostasis. Deregulated or dysfunctional microglia can, on the other hand, be critical or at least instrumental in a harmful way. Excessive and chronic reaction of microglia can then fuel destructive cascades upon trauma or during inflammatory and neurodegenerative proce作者: 確定方向 時(shí)間: 2025-3-23 00:28 作者: LAP 時(shí)間: 2025-3-23 04:46 作者: 詞匯表 時(shí)間: 2025-3-23 09:24 作者: ANA 時(shí)間: 2025-3-23 12:40 作者: arrogant 時(shí)間: 2025-3-23 13:55 作者: Detain 時(shí)間: 2025-3-23 20:33 作者: Intrepid 時(shí)間: 2025-3-23 22:13
F. F. Faletra,T. Moccetti,G. Pedrazzini protein diversity and determine the subcellular location, molecular interactions, or function of proteins. Neuron-specific proteins involved in RNA splicing and metabolism are affected in several neurological disorders. Defects in RNA processing proteins, such as SMN protein, may lead to the Spinal作者: 謊言 時(shí)間: 2025-3-24 06:03
F. F. Faletra,T. Moccetti,G. Pedrazzinin’s disease increased levels of biomarkers of oxidative and nitrosative stress have been identified in the brain. Some of which such as hydroxyalkenals and isoprostanes may even gain diagnostic value for the determination of the degree of neurodegeneration. However, scientific efforts have to be con作者: 乳汁 時(shí)間: 2025-3-24 07:52 作者: Ondines-curse 時(shí)間: 2025-3-24 11:43
Conclusions, Suggestions and Prospects,of the main processes that regulate Schwann-cell biology is a requisite for the use of this interesting cell population — with proven neurotrophic and regenerative properties — in cell therapy for human diseases作者: evanescent 時(shí)間: 2025-3-24 16:24 作者: 磨碎 時(shí)間: 2025-3-24 22:08 作者: 植物群 時(shí)間: 2025-3-24 23:27 作者: 生銹 時(shí)間: 2025-3-25 06:52
https://doi.org/10.1007/978-88-470-1060-4function in the body. After a brief historical review, the peculiar nature of neuronal size and shape are considered, together with the consequences of this for neuronal classification, connectivity, excitability, intracellular transport and vulnerability to injury. This is followed by a description作者: acheon 時(shí)間: 2025-3-25 10:43 作者: Frequency 時(shí)間: 2025-3-25 15:28
https://doi.org/10.1007/978-88-470-1060-4ties, delivery of molecules via intra-axonal transport and support from external cellular and extracellular sources. Trauma, ischemia, toxic agents, metabolic disturbances, inflammatory conditions and inadequate axon-glial interactions result in axonal disintegration. This process is characterized b作者: JIBE 時(shí)間: 2025-3-25 17:00
https://doi.org/10.1007/978-88-470-1060-4es and after acute brain insults. Neuronal apoptosis which has a crucial function for elimination of unwanted neurons in the immature nervous system, for a long time was thought to be restricted to this type of developmental cell death. In recent years however, evidence has accumulated that apoptosi作者: 使迷醉 時(shí)間: 2025-3-25 23:18 作者: Rct393 時(shí)間: 2025-3-26 01:42
https://doi.org/10.1007/978-88-470-1060-4synthesized membrane and secretory proteins are folded and processed in this subcellular compartment. These are strictly calcium-dependent processes that need for correct functioning a calcium activity in the range close to that of the extracellular space. Under conditions associated with ER dysfunc作者: Recessive 時(shí)間: 2025-3-26 05:49
F. F. Faletra,T. Moccetti,G. Pedrazzinising. Multiple proteins involved in RNA transcription and pre-mRNA processing can interact with general transcription factors and transcriptional activators, which associate with polymerase at gene promoters. Huntington’s disease, dentatorubralpallidoluysian atrophy and five spinocerebellar ataxias 作者: 調(diào)整 時(shí)間: 2025-3-26 10:42
F. F. Faletra,T. Moccetti,G. Pedrazzini process originating from enzyme catalyzed redox reactions triggered by the turnover of endogenous and exogenous substrates. Due to the high reactivity of radicals, covalent modifications of lipids, proteins and DNA are likely to occur if radicals are not trapped by scavengers such as tocopherol, as作者: Peristalsis 時(shí)間: 2025-3-26 14:45
https://doi.org/10.1007/978-981-97-4220-2he distribution of local and long-range guidance cues. Gradients of long-range guidance cues have been associated with growth cone function for over a hundred years, but their developmental roles are still poorly understood. Here we review the developmental roles and the complex intracellular signal作者: 我們的面粉 時(shí)間: 2025-3-26 17:40 作者: 使迷醉 時(shí)間: 2025-3-27 00:57 作者: 碳水化合物 時(shí)間: 2025-3-27 04:53 作者: Impugn 時(shí)間: 2025-3-27 08:22 作者: 障礙 時(shí)間: 2025-3-27 12:31 作者: Infiltrate 時(shí)間: 2025-3-27 14:33 作者: 異端 時(shí)間: 2025-3-27 21:37
Problemstellung und Zielsetzung,al by having two unpaired eletrons it is not very reactive. However, in the presence of catalytic concentrations of free metal ions or reactive oxygen species, oxidative damage may occur. Such damage may be counteracted by superoxide dismutases, glutathione peroxidase, and metallothioneins. Antioxid作者: 哀求 時(shí)間: 2025-3-27 22:45 作者: 共同時(shí)代 時(shí)間: 2025-3-28 05:06
T. Herdegen,J. Delgado-GarcíaAims at building a novel bridge from molecular research to clinical therapy.omprehensive chapters on neurological diseases, such as M. Alzheimer, M. Parkinson, ALS, stroke or trauma, take this knowled作者: facilitate 時(shí)間: 2025-3-28 09:53
http://image.papertrans.cn/b/image/190142.jpg作者: Axon895 時(shí)間: 2025-3-28 10:30
https://doi.org/10.1007/978-88-470-1060-4 of the ways organelles are distributed and organised within neurones and the functional correlates of this. Finally, synaptic terminal structure is considered in the context of electrical and trophic interactions作者: debble 時(shí)間: 2025-3-28 17:51 作者: Focus-Words 時(shí)間: 2025-3-28 21:37
Conclusions and recommendations,protecting the neurons from dead. Moreover, Müller cells play an important role in neuroprotection, inflammatory processes or phagocytosis after damage, developing important processes for tissue repair after injury. These aspects and others developed by the Müller cells will be reviewed in the present chapter.作者: 缺陷 時(shí)間: 2025-3-29 00:01
Book 2004 to clinical therapy. This novel approach reveals the functional features of neurons and glia in the particular context of vulnerability and self-protection, intracellular properties and extracellular matrix. Arising from this platform, this volume unfolds the molecular and systemic processes underl作者: 獸皮 時(shí)間: 2025-3-29 05:49 作者: pellagra 時(shí)間: 2025-3-29 07:52
Generation and Differentiation of Astrocytes During Central Nervous System Development And Injuryd astrocytes, vimentin is replaced by GFAP. The molecular mechanisms controlling astrocyte generation and differentiation from multipotent cells include the actions of diffusible factors (CNTF and BMP, among others), cell-cell interactions (Delta/Notch) and bHLH transcription factors.作者: POINT 時(shí)間: 2025-3-29 11:47
The Müller Glia: Role in Neuroprotectionprotecting the neurons from dead. Moreover, Müller cells play an important role in neuroprotection, inflammatory processes or phagocytosis after damage, developing important processes for tissue repair after injury. These aspects and others developed by the Müller cells will be reviewed in the present chapter.作者: paragon 時(shí)間: 2025-3-29 19:22
Navigare in un cielo sferico ruotante able to prevent such brain disorders. In this respect, focus is laid on oxidative energy and related metabolism what had been demonstrated to meet the functional and structural requirements of the brain.作者: 正論 時(shí)間: 2025-3-29 21:32 作者: 膠狀 時(shí)間: 2025-3-30 03:19
Conclusions and recommendations,, which are sometimes confused with neural plastic processes. As a practical support to the concepts proposed here, some illustrative examples, collected from animal experimentation carried out in our laboratory, will be described briefly.作者: Aggrandize 時(shí)間: 2025-3-30 07:28
The Aging Brain — the Burden of Life (?) able to prevent such brain disorders. In this respect, focus is laid on oxidative energy and related metabolism what had been demonstrated to meet the functional and structural requirements of the brain.作者: Occipital-Lobe 時(shí)間: 2025-3-30 10:16 作者: Minikin 時(shí)間: 2025-3-30 12:36
Neural Plasticity and Regeneration: Myths and Expectations, which are sometimes confused with neural plastic processes. As a practical support to the concepts proposed here, some illustrative examples, collected from animal experimentation carried out in our laboratory, will be described briefly.作者: INCH 時(shí)間: 2025-3-30 18:26
imer, M. Parkinson, ALS, stroke or trauma, take this knowled.Brain Damage and Repair. aims to attract the interest of neuroscientists and clinical neurologists by building a novel bridge from molecular research to clinical therapy. This novel approach reveals the functional features of neurons and g作者: Override 時(shí)間: 2025-3-30 22:48
Conclusions, Suggestions and Prospects,herapeutic targets for demyelinating diseases. We also summarize some relevant advances in the etiology of multiple sclerosis, the most frequent disease involving oligodendrocyte and myelin loss, and new concepts as to how white-matter damage during ischemia contributes to the clinical outcome of stroke in humans.作者: 皮薩 時(shí)間: 2025-3-31 02:48 作者: ESPY 時(shí)間: 2025-3-31 07:00
Oligodendrocytes in Health and Diseaseherapeutic targets for demyelinating diseases. We also summarize some relevant advances in the etiology of multiple sclerosis, the most frequent disease involving oligodendrocyte and myelin loss, and new concepts as to how white-matter damage during ischemia contributes to the clinical outcome of stroke in humans.作者: 適宜 時(shí)間: 2025-3-31 11:51
Neuronal Protection Against Oxidative Damage species, oxidative damage may occur. Such damage may be counteracted by superoxide dismutases, glutathione peroxidase, and metallothioneins. Antioxidant protectors can be generated by ascorbic acid and a-tocopherol. Oxidative mechanisms in neurodegenerative diseases are exemplified by Alzheimer’s disesase.作者: 偽證 時(shí)間: 2025-3-31 14:31
Book 2004 ALS, stroke or trauma, take this knowledge, apply it at the clinical level to provide a basis for novel therapeutic strategies. .Brain Damage and Repair. is completed with chapters on imaging techniques, viral gene transfer or legal international handling of stem cell transfer and patents of DNA/proteins.作者: Gorilla 時(shí)間: 2025-3-31 17:55
https://doi.org/10.1007/978-88-470-1060-4cium blockers, a variety of growth factors, immune suppressants, antiinflammatory agents, as well as free radical scavengers. The recent identification of a gene, which “protects” axons from undergoing degeneration, provides a basis for a genetic approach to the treatment of neurological disorders caused by axonal disease or trauma.作者: CRANK 時(shí)間: 2025-4-1 01:44
https://doi.org/10.1007/978-981-97-4220-2ading edge; and through intracellular kinases, which have the potential to alter gene expression changes in the developing neuron. In addition, we also summarize the increasing body of knowledge on their roles in the inhibition of axon regeneration after adult lesions in the central and peripheral nervous system.作者: 嫻熟 時(shí)間: 2025-4-1 03:35 作者: SPASM 時(shí)間: 2025-4-1 06:55 作者: 舊石器時(shí)代 時(shí)間: 2025-4-1 10:58
The Aging Brain — the Burden of Life (?)veral brain diseases in middle, and more frequently, in old age such as stroke (brain ischemia), Parkinson’s disease and dementia of either vascular origin or sporadic Alzheimer type..Cellular and molecular mechanisms in mammalian brain during adult life and their variations in old age will be discu作者: MELON 時(shí)間: 2025-4-1 16:33 作者: 口音在加重 時(shí)間: 2025-4-1 22:04 作者: profligate 時(shí)間: 2025-4-2 00:11
Synaptic Plasticity: Hyperexcitability and Synaptic Silencingres. Long-lasting increase or decrease of synaptic efficacy — termed long-term potentiation (LTP) and long-term depression (LTD), respectively — has been related to the establishment of memory traces. Experimental induction of both types of long-lasting changes has contributed effectively to the stu作者: DOTE 時(shí)間: 2025-4-2 03:19 作者: 替代品 時(shí)間: 2025-4-2 07:02 作者: arterioles 時(shí)間: 2025-4-2 12:37
The Organelles, I: Mitochondrial Failure And Neurodegenerationtion of apoptosis, a program of cell death. The molecular components required for the functional activities of mitochondria are very vast and are encoded in both the nuclear and the mitochondrial genomes. Therefore, mutations and/or epigenetic factors that affect the activity of any of the gene prod作者: 發(fā)出眩目光芒 時(shí)間: 2025-4-2 17:13
The Organelles II: Endoplasmic Reticulum and its Overloadsynthesized membrane and secretory proteins are folded and processed in this subcellular compartment. These are strictly calcium-dependent processes that need for correct functioning a calcium activity in the range close to that of the extracellular space. Under conditions associated with ER dysfunc
