標(biāo)題: Titlebook: Boundaries between Promotion and Progression during Carcinogenesis; Oscar Sudilovsky,Henry C. Pitot,Lance A. Liotta Book 1991 Plenum Press [打印本頁] 作者: Asphyxia 時(shí)間: 2025-3-21 16:49
書目名稱Boundaries between Promotion and Progression during Carcinogenesis影響因子(影響力)
書目名稱Boundaries between Promotion and Progression during Carcinogenesis影響因子(影響力)學(xué)科排名
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書目名稱Boundaries between Promotion and Progression during Carcinogenesis網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Boundaries between Promotion and Progression during Carcinogenesis被引頻次
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書目名稱Boundaries between Promotion and Progression during Carcinogenesis年度引用學(xué)科排名
書目名稱Boundaries between Promotion and Progression during Carcinogenesis讀者反饋
書目名稱Boundaries between Promotion and Progression during Carcinogenesis讀者反饋學(xué)科排名
作者: 輪流 時(shí)間: 2025-3-21 20:51
Interval 1: Grandma Baré’s Diaryulated proliferation. However, the appearance of a tumor is not really an endpoint in this process, and the more general term, progression, refers to the continuous evolution in characters both before and after a tumor has formed.作者: TSH582 時(shí)間: 2025-3-22 04:25 作者: Temporal-Lobe 時(shí)間: 2025-3-22 08:21 作者: 服從 時(shí)間: 2025-3-22 11:50 作者: Rejuvenate 時(shí)間: 2025-3-22 15:44
Introduction to Loop Transformationst both genetic and epigenetic mechanisms are important. Altered growth control and differentiation leading to a more embryonic phenotype appear to be critical consequences of the genetic and epigenetic changes.作者: Immobilize 時(shí)間: 2025-3-22 20:58
Reformulating Imperial Authority,ion, while Dr. Slaga expressed the opinion that both processes exist as a continuum. So I would like to start the discussion by asking Dr. Pitot how he would contrast his belief with those of Dr. Slaga.作者: 兇猛 時(shí)間: 2025-3-22 21:46
https://doi.org/10.1007/978-1-349-02565-7 appear to persist in the embryonic portion of the embryo up until 7.5 days.. These undetermined pluripotent stem cells have been established as permanent tissue culture cell lines either directly from the embryo (embryonic stem (ES) cells). or indirectly from teratocarcinoma tumors (embryonal carcinoma (EC) cells) (See Fig. 1).作者: ethnology 時(shí)間: 2025-3-23 04:04
https://doi.org/10.1057/9780230514003and experimental rodent models. Attempts to develop a cohesive picture of how these factors participate in mammary tumorigenesis have been hampered, in part, by a lack of information on the specific genetic lesions that contribute to the initiation and/or evolution of tumor development.作者: Corporeal 時(shí)間: 2025-3-23 07:51
Transkulturalit?t – Translation – Transfery, tumors induced by such viruses in animals are all polyclonal. Such viruses have never been found in healthy animals, a statement that cannot be made for retroviruses without . genes or DNA tumor viruses, which are commonly found in animals outside the laboratory and only transform cells indirectly and inefficiently..作者: photopsia 時(shí)間: 2025-3-23 13:37 作者: 包租車船 時(shí)間: 2025-3-23 15:53 作者: hidebound 時(shí)間: 2025-3-23 18:44
Developmental Potential of Murine Pluripotential Stem Cells appear to persist in the embryonic portion of the embryo up until 7.5 days.. These undetermined pluripotent stem cells have been established as permanent tissue culture cell lines either directly from the embryo (embryonic stem (ES) cells). or indirectly from teratocarcinoma tumors (embryonal carcinoma (EC) cells) (See Fig. 1).作者: 本土 時(shí)間: 2025-3-24 00:35 作者: Cervical-Spine 時(shí)間: 2025-3-24 05:36 作者: ligature 時(shí)間: 2025-3-24 09:05
Book 1991ocus was to concentrate on the mechanistic similarities between promotion and progression. Are the areas involved within the boundaries a continuum? Are these two simultaneous processes? Or are some of the affected cells in the stage of promotion when at the same time others have undergone irreversi作者: 多骨 時(shí)間: 2025-3-24 12:47 作者: 信任 時(shí)間: 2025-3-24 16:55
https://doi.org/10.1057/9780230514003ate levels of messenger are elevated at specific stages in skin tumor formation can serve to define the stages of promotion and progression. There is also the possibility that overexpression of one or a number of these genes actually plays a functional role in tumor formation.作者: Magnificent 時(shí)間: 2025-3-24 22:41
https://doi.org/10.1007/978-3-319-98155-0ased propensities for the development of tumors. Tumors often have specific chromosomal rearrangements and, sometimes, such aberrations resemble those which, when inherited, predispose to similar disease.作者: 充氣女 時(shí)間: 2025-3-24 23:27 作者: 信徒 時(shí)間: 2025-3-25 05:29 作者: eardrum 時(shí)間: 2025-3-25 09:56 作者: 美色花錢 時(shí)間: 2025-3-25 11:45
Introduction: Is There a Boundary between Promotion and Progression?Gordon Conference on Cancer in August, 1987. It had become evident to me and other participants that the concepts of promotion and progression as two separate stages in a multi-step model of carcinogenesis required further evaluation.作者: 辮子帶來幫助 時(shí)間: 2025-3-25 16:50
Characterization of the Stage of Progression in Hepatocarcinogenesis in the Rate stage of initiation as that which established “a persistent region of . whence tumors of varied kinds emerge at a later time”.. All of the remainder of neoplastic development he termed progression. In a sense, such a concept was quite analogous to that proposed earlier by several authors as the st作者: GRIPE 時(shí)間: 2025-3-25 20:41 作者: Nonflammable 時(shí)間: 2025-3-26 02:56
Malignant Conversion, the First Stage in Progression, is Distinct from Phorbol Ester Promotion in Monogenesis.. Although skin tumors can be induced by repeated topical applications of a carcinogen., protocols have been developed which define at least three distinct stages: initiation, promotion and malignant conversion.. In a typical experiment, the first stage, initiation, is accomplished by a si作者: macrophage 時(shí)間: 2025-3-26 04:56 作者: arthrodesis 時(shí)間: 2025-3-26 10:45
Discussion of Sessionmotion and progression. Dr. Pitot, if I interpret him correctly, said that the effect of promoting agents can extend to cells in the stage of progression, while Dr. Slaga expressed the opinion that both processes exist as a continuum. So I would like to start the discussion by asking Dr. Pitot how h作者: Cryptic 時(shí)間: 2025-3-26 14:57
Progression in Teratocarcinomash (1953), and of recalling many pleasant and stimulating discussions with each of them. Foulds studied solid tumors, primarily adenocarcinomas of the breast, and his definition of progression as the independent and irreversible gain or loss of unit characters with time leading to the autonomous stat作者: nonsensical 時(shí)間: 2025-3-26 17:34
Developmental Potential of Murine Pluripotential Stem Cellsncluding the germ line.. As the ICM cells proliferate, groups of these cells become committed to specific developmental pathways. Pluripotential cells appear to persist in the embryonic portion of the embryo up until 7.5 days.. These undetermined pluripotent stem cells have been established as perma作者: 疾馳 時(shí)間: 2025-3-26 23:44
Summary by Moderator this interaction can modify the development or reversal of malignancy. In the case of ES cells produced in vitro from explanted embryos the moment of explantation could be considered as initiation. It is arguable whether there is any promotion or progression. It is, however, unquestionable that the作者: 強(qiáng)壯 時(shí)間: 2025-3-27 02:06
Tumor Progression in Transgenic Mice Containing the Bovine Papillomavirus Genomeis. It has provided a tractable system to study and to dissect the multiple steps involved in carcinogenesis, essentially by fixing one of these steps.. In transgenic mice, DNA is introduced into the germ line and that gene is stably inherited to the offspring of the mice. Transgenic mice have been 作者: 紡織品 時(shí)間: 2025-3-27 05:58 作者: 山崩 時(shí)間: 2025-3-27 10:25
Differential Gene Expression During Tumor Promotion and Progression in the Mouse Skin Modelmor formation can be identified. Once operational definitions have been made, investigators can and should pursue questions of molecular mechanisms to explain phenotypic changes that occur during promotion and progression. This paper deals with the identification and characterization of molecular ma作者: judiciousness 時(shí)間: 2025-3-27 14:05
Oncogenes and Breast Cancer Progressionogical status of the host. Extensive studies have been undertaken to determine the relationship between these factors and tumor development in humans and experimental rodent models. Attempts to develop a cohesive picture of how these factors participate in mammary tumorigenesis have been hampered, i作者: Arb853 時(shí)間: 2025-3-27 21:38
Gene Amplification During Stages of Carcinogenesiselated concepts of promotion and progression describe an essential feature of carcinogenesis, the gradual change from a normal cell to a tumor composed of proliferating, invading, metastasizing cells. Promotion is the gradual conversion of undetectable initiated cells to tumors without the continuin作者: EWE 時(shí)間: 2025-3-27 23:34
Recessive Mutations in Cancer Predisposition and Progressionf the present volume. There is a great deal of circumstantial evidence in its support which arises from examination of human populations.. There has been, for example, extensive documentation of familial aggregation of specific histological types of tumors, sometimes developing with the formal behav作者: Gyrate 時(shí)間: 2025-3-28 04:01 作者: THE 時(shí)間: 2025-3-28 08:20 作者: Nausea 時(shí)間: 2025-3-28 11:20 作者: Banister 時(shí)間: 2025-3-28 18:36 作者: 無畏 時(shí)間: 2025-3-28 20:11 作者: Foam-Cells 時(shí)間: 2025-3-29 01:16
Introduction to Loop TransformationsGordon Conference on Cancer in August, 1987. It had become evident to me and other participants that the concepts of promotion and progression as two separate stages in a multi-step model of carcinogenesis required further evaluation.作者: 繁榮中國 時(shí)間: 2025-3-29 05:25
Introduction to Loop Transformationse stage of initiation as that which established “a persistent region of . whence tumors of varied kinds emerge at a later time”.. All of the remainder of neoplastic development he termed progression. In a sense, such a concept was quite analogous to that proposed earlier by several authors as the st作者: 平淡而無味 時(shí)間: 2025-3-29 10:19 作者: Charitable 時(shí)間: 2025-3-29 12:58
Introduction to Loop Transformationsnogenesis.. Although skin tumors can be induced by repeated topical applications of a carcinogen., protocols have been developed which define at least three distinct stages: initiation, promotion and malignant conversion.. In a typical experiment, the first stage, initiation, is accomplished by a si作者: 不如樂死去 時(shí)間: 2025-3-29 15:57
Introduction to Loop Transformations this work are: what causes breast cancer? how does breast cancer start? what determines the susceptibility of the gland to undergo carcinogenesis? what makes an initiated cell progress to a fully malignant one?作者: LINES 時(shí)間: 2025-3-29 20:33 作者: 木訥 時(shí)間: 2025-3-30 01:05
https://doi.org/10.1057/9780230514768h (1953), and of recalling many pleasant and stimulating discussions with each of them. Foulds studied solid tumors, primarily adenocarcinomas of the breast, and his definition of progression as the independent and irreversible gain or loss of unit characters with time leading to the autonomous stat作者: condemn 時(shí)間: 2025-3-30 05:42 作者: 不妥協(xié) 時(shí)間: 2025-3-30 09:39 作者: aspect 時(shí)間: 2025-3-30 13:00
https://doi.org/10.1007/978-1-349-08348-0is. It has provided a tractable system to study and to dissect the multiple steps involved in carcinogenesis, essentially by fixing one of these steps.. In transgenic mice, DNA is introduced into the germ line and that gene is stably inherited to the offspring of the mice. Transgenic mice have been 作者: 擁護(hù) 時(shí)間: 2025-3-30 18:22
Lord of the Flies by William Goldingpearance. Indeed, one aspect of tumor progression may be the evolution and selection of tumor cell variants capable of avoiding the immune response of the host. The oncogenic virus-induced tumors have provided the most direct evidence for these points; viral gene products elicit specific immune resp作者: 清唱?jiǎng)?nbsp; 時(shí)間: 2025-3-30 23:41
https://doi.org/10.1057/9780230514003mor formation can be identified. Once operational definitions have been made, investigators can and should pursue questions of molecular mechanisms to explain phenotypic changes that occur during promotion and progression. This paper deals with the identification and characterization of molecular ma作者: BLANC 時(shí)間: 2025-3-31 04:36 作者: 創(chuàng)造性 時(shí)間: 2025-3-31 06:25
Interval 1: Grandma Baré’s Diaryelated concepts of promotion and progression describe an essential feature of carcinogenesis, the gradual change from a normal cell to a tumor composed of proliferating, invading, metastasizing cells. Promotion is the gradual conversion of undetectable initiated cells to tumors without the continuin作者: 寬宏大量 時(shí)間: 2025-3-31 12:54 作者: landmark 時(shí)間: 2025-3-31 15:48 作者: DRILL 時(shí)間: 2025-3-31 18:02
Transkulturalit?t – Translation – Transfersform diploid cells in culture with single hit kinetics, and because all susceptible cells become transformed as soon as they are infected. Accordingly, tumors induced by such viruses in animals are all polyclonal. Such viruses have never been found in healthy animals, a statement that cannot be mad作者: 哀求 時(shí)間: 2025-3-31 21:54
,Perturbative Generation of?LV Terms,n expression, or lost, and this correlates with tumorigenesis and progression to metastases. Others may be are up-regulated genes that encode for enzymes or cytoskeletal elements. Some of these may be so-called suppressor genes. Their function is unknown. There may be even suppressor genes for the m作者: Notify 時(shí)間: 2025-4-1 05:36
