標(biāo)題: Titlebook: Bone-Metabolic Functions and Modulators; Felix Bronner,Mary C. Farach-Carson,Helmtrud I. Ro Book 2012 Springer-Verlag London 2012 metaboli [打印本頁(yè)] 作者: 有判斷力 時(shí)間: 2025-3-21 20:06
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作者: zonules 時(shí)間: 2025-3-21 20:50 作者: DAUNT 時(shí)間: 2025-3-22 00:34 作者: tolerance 時(shí)間: 2025-3-22 06:45 作者: 赦免 時(shí)間: 2025-3-22 12:42
Load-Oriented Manufacturing Controle also critical for the regulation of bone turnover as they are a significant source of OPG in the BM microenvironment [44]. Consequently, lymphocytes play critical roles in the stabilization of bone homeostasis. Pathological disruption of immune function as occurs during HIV-1 infection contributes作者: 頌揚(yáng)國(guó)家 時(shí)間: 2025-3-22 16:57 作者: inferno 時(shí)間: 2025-3-22 18:12 作者: engender 時(shí)間: 2025-3-23 01:00
Pituitary Hormones and the Pathophysiology of Osteoporosis,er understanding of bone pathophysiology and opens up new avenues for treatment of osteoporosis. In this chapter, we discuss the interaction of each pituitary hormone with bone and the potential that targeting these interactions holds in management of osteoporosis.作者: 引起 時(shí)間: 2025-3-23 05:13
Diseases of Energy and Lipid Metabolism and Bone: Emerging Therapeutics,ications similar to those in type 2 diabetes, i.e., insulin resistance, dyslipidemia, hyperphagia, and liver steatosis. On the other hand, excessive lipid storage leads to obesity, along with a multitude of manifestations and clinical complications including altered insulin production. Fatty tissue 作者: 冰雹 時(shí)間: 2025-3-23 09:34
Renal Diseases and Bone: Emerging Therapeutics, no one pharmacologic therapy that will independently correct the disordered mineral metabolism of CKD. This chapter will concentrate on the skeletal disorders associated with metabolic acidosis [45, 46].作者: 銼屑 時(shí)間: 2025-3-23 12:55 作者: 絆住 時(shí)間: 2025-3-23 15:36
Bone and the cAMP Signaling Pathway: Emerging Therapeutics,fector termed ROCK (Rho-associated kinase). Once activated by RhoA, ROCK promotes phosphorylation of myosin light chain (MLC), producing increased contractility and stress fiber formation, necessary for motility [25]. In osteoclasts, RhoA is activated by engagement of the αV/β3 integrin receptor and作者: 鬧劇 時(shí)間: 2025-3-23 18:19
Nervous System Diseases, Disorders, and Bone: Emerging Therapeutics and Treatment Options,eleased by osteoclasts), but also by neuronal signals released from the peripheral and central nervous systems. This has created a new field of neuroskeletal biology from which key findings are covered in this chapter.作者: 強(qiáng)化 時(shí)間: 2025-3-24 01:53
Book 2012s. is the seventh volume in the series Topics in Bone Biology, edited by Felix Bronner and Mary C. Farach-Carson..Other titles in this series:-.Bone Formation.Bone Resorption .Engineering of Functional Skeletal Tissues.Bone and Osteoarthritis.Bone and Cancer.Bone and Development.Bone- Metabolic Func作者: hankering 時(shí)間: 2025-3-24 05:46
Bone-Metabolic Functions and Modulators978-1-4471-2745-1Series ISSN 2199-2436 Series E-ISSN 2199-2444 作者: 無(wú)動(dòng)于衷 時(shí)間: 2025-3-24 09:32 作者: 陳腐的人 時(shí)間: 2025-3-24 11:04 作者: CLOT 時(shí)間: 2025-3-24 15:52 作者: 分離 時(shí)間: 2025-3-24 21:30 作者: 暴露他抗議 時(shí)間: 2025-3-25 01:20
Fibres, Whiskers, and Platelets,n calcium homeostasis and bone formation. PTH was discovered in the acid extracts of parathyroid glands because it restored the blood calcium level in the parathyroidectomized dog [24]. The existence of PTHrP and its close resemblance to PTH was first suggested by Fuller Albright in 1941 and later d作者: 駁船 時(shí)間: 2025-3-25 04:17 作者: Trabeculoplasty 時(shí)間: 2025-3-25 10:05 作者: cipher 時(shí)間: 2025-3-25 12:23
https://doi.org/10.1007/b118150 development of the skeleton. In the adult, thyroid hormones stimulate both anabolic and resorptive activity, with an age-dependent increase in resorption over formation. Both systemic and local environment factors influence how thyroid hormones affect the quantity and nature of bone responses. Fina作者: CHIDE 時(shí)間: 2025-3-25 18:33 作者: Inkling 時(shí)間: 2025-3-25 20:17 作者: myriad 時(shí)間: 2025-3-26 00:55 作者: 鞠躬 時(shí)間: 2025-3-26 07:45 作者: 手榴彈 時(shí)間: 2025-3-26 08:37 作者: 群島 時(shí)間: 2025-3-26 16:31
Architecture of the Unified Load Generatorts. Persons with wasting disorders have a particularly high risk of bone disease, due to their direct impact on lean muscle mass, which is both a key determinant of childhood bone accrual and is important for the maintenance of bone mineral density (BMD) and bone mineral content (BMC) in adults.作者: relieve 時(shí)間: 2025-3-26 19:39
Distributed UniLoG Architectureot the entire skeleton. Radiological and pathological studies indicate that the underlying problem is an increase in osteoclastic activity, which initially produces dominant osteolytic lesions that move slowly throughout an affected bone. Over time, the osteolytic areas are replaced by osteoscleroti作者: Euthyroid 時(shí)間: 2025-3-26 23:48 作者: 翅膀拍動(dòng) 時(shí)間: 2025-3-27 01:56 作者: happiness 時(shí)間: 2025-3-27 05:45
Load-Oriented Manufacturing Controlearing function is assured by the sequential collaboration of three different parts of the ear – the outer ear that captures the acoustic signal, the middle ossicles that transmit an amplified signal to the cochlea, and the inner ear that harbors the sensory cells. The inner ear, consisting of the c作者: 小故事 時(shí)間: 2025-3-27 13:05 作者: 匯總 時(shí)間: 2025-3-27 16:44 作者: bronchodilator 時(shí)間: 2025-3-27 18:10 作者: Alcove 時(shí)間: 2025-3-27 22:05 作者: 動(dòng)機(jī) 時(shí)間: 2025-3-28 02:17 作者: stress-response 時(shí)間: 2025-3-28 08:02
Gonadal Hormones, Diseases, and Emerging Therapeutics,iate the discussion with disorders that occur at the level of the target organs, the testes and ovaries, and then consider defects of the pituitary and hypothalamus. Discussion will focus on common disorders of primary and secondary hypogonadism in men and women, including their diagnosis and therapeutic strategies for treatment of these diseases.作者: 解脫 時(shí)間: 2025-3-28 13:46
,Paget’s Disease of Bone: Pathogenesis and Treatment,c bone of increased size and chaotic structure. In the lower extremities, affected bones may become bowed due to impaired biomechanical properties of the bone. The overgrowth of bone is produced by a marked proliferation of osteoblasts.作者: 記憶 時(shí)間: 2025-3-28 17:14
Book 2012t system, but also functions as an integrating organ, with a significant regulatory role for lipid and energy metabolism. Links between physical activity and the skeleton are also becoming increasingly clear. This fully illustrated volume contains up-to-date information on the metabolic role of the 作者: 相容 時(shí)間: 2025-3-28 20:24 作者: Distribution 時(shí)間: 2025-3-28 23:45 作者: 感情 時(shí)間: 2025-3-29 04:11
A Formal Workload Description Techniqueloskeletal system were recognized, the full extent of the changes was not known. Therefore, studies were planned and conducted by the emerging American and Soviet space programs to determine the extent of, and potential harm associated with, bone loss that might occur during space flight.作者: 保守黨 時(shí)間: 2025-3-29 10:58 作者: Organonitrile 時(shí)間: 2025-3-29 15:11 作者: 允許 時(shí)間: 2025-3-29 15:53
Bone Loss in Space Flight and Countermeasures,loskeletal system were recognized, the full extent of the changes was not known. Therefore, studies were planned and conducted by the emerging American and Soviet space programs to determine the extent of, and potential harm associated with, bone loss that might occur during space flight.作者: chastise 時(shí)間: 2025-3-29 21:00 作者: 不愿 時(shí)間: 2025-3-30 03:55
https://doi.org/10.1007/978-3-658-19102-3still are, the dominant pharmacological agent utilized to treat PMO [43, 47, 62, 66, 70]. Bisphosphonates this year celebrate their 40th anniversary since their introduction into clinical medicine [61].作者: MUT 時(shí)間: 2025-3-30 04:54
Diseases of Mineral Metabolism and Bone: Emerging Therapeutics for Postmenopausal Osteoporosiss,still are, the dominant pharmacological agent utilized to treat PMO [43, 47, 62, 66, 70]. Bisphosphonates this year celebrate their 40th anniversary since their introduction into clinical medicine [61].作者: 撤退 時(shí)間: 2025-3-30 10:49
Fibres, Whiskers, and Platelets,from tumors. The past two decades have witnessed an explosion in the knowledge of the biological function of these peptides at the molecular level and their use as therapeutics or as targets in certain diseases. This chapter will review their functions in bone.作者: FANG 時(shí)間: 2025-3-30 16:15
Composite Mechanics: Short Fibres, of vitamin D. Upon reaching target tissues, 1,25(OH).D binds to its specific receptor, the vitamin D receptor (VDR). This step enhances or inhibits the transcription of vitamin D target genes that carry out the physiological actions of 1,25(OH).D: mineral homeostasis, skeletal homeostasis, and cellular differentiation.作者: Analogy 時(shí)間: 2025-3-30 20:05 作者: 狂亂 時(shí)間: 2025-3-30 20:45 作者: Consensus 時(shí)間: 2025-3-31 00:56
Vitamin D: Normal Function, Metabolism, Diseases, and Emerging Therapeutics, of vitamin D. Upon reaching target tissues, 1,25(OH).D binds to its specific receptor, the vitamin D receptor (VDR). This step enhances or inhibits the transcription of vitamin D target genes that carry out the physiological actions of 1,25(OH).D: mineral homeostasis, skeletal homeostasis, and cellular differentiation.作者: Acetaminophen 時(shí)間: 2025-3-31 08:30 作者: 官僚統(tǒng)治 時(shí)間: 2025-3-31 10:40 作者: compose 時(shí)間: 2025-3-31 16:20 作者: 擔(dān)心 時(shí)間: 2025-3-31 19:27
Parathyroid Hormone and Parathyroid-Hormone-Related Protein: Normal Function, Diseases, and Emerginn calcium homeostasis and bone formation. PTH was discovered in the acid extracts of parathyroid glands because it restored the blood calcium level in the parathyroidectomized dog [24]. The existence of PTHrP and its close resemblance to PTH was first suggested by Fuller Albright in 1941 and later d作者: Flounder 時(shí)間: 2025-3-31 23:33
Vitamin D: Normal Function, Metabolism, Diseases, and Emerging Therapeutics,l ion homeostasis. Vitamin D becomes bound to the vitamin D binding protein, DBP, in the circulation and is transported to the liver where the enzyme vitamin D 25-hydroxylase (CYP2R1) adds a hydroxyl group on carbon 25 to produce 25-hydroxyvitamin D [25(OH)D]. When the 25(OH)D metabolite enters the 作者: 漂亮才會(huì)豪華 時(shí)間: 2025-4-1 03:01 作者: –LOUS 時(shí)間: 2025-4-1 09:07 作者: 謙卑 時(shí)間: 2025-4-1 12:32 作者: jet-lag 時(shí)間: 2025-4-1 14:37 作者: 觀點(diǎn) 時(shí)間: 2025-4-1 20:01
Diseases of Energy and Lipid Metabolism and Bone: Emerging Therapeutics,ling molecules. Lipids and fatty acids are stored as triglycerides and are the most important source of energy for most organisms. When the body needs energy, lipolysis is initiated in adipocytes, and the triglycerides are hydrolyzed to glycerol and nonesterified fatty acids (NEFAs) [64]. The capaci作者: AMITY 時(shí)間: 2025-4-1 23:48
