標(biāo)題: Titlebook: Blood Substitutes and Oxygen Biotherapeutics; Henry Liu,Alan D. Kaye,Jonathan S. Jahr Book 2022 The Editor(s) (if applicable) and The Auth [打印本頁] 作者: mandatory 時(shí)間: 2025-3-21 18:50
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作者: 怎樣才咆哮 時(shí)間: 2025-3-21 22:36 作者: 核心 時(shí)間: 2025-3-22 02:01 作者: 白楊魚 時(shí)間: 2025-3-22 08:27 作者: 濃縮 時(shí)間: 2025-3-22 09:29
The Global Burden of Anemiarrogate marker for red blood cell mass, with anemia typically being defined by a hemoglobin concentration less than 13?g/dL in adult men and less than 12?g/dL in adult, non-pregnant women. Anemia is remarkably common globally, though low- and middle-income countries bear the greatest burden. Anemia 作者: 油氈 時(shí)間: 2025-3-22 15:22
Blood Component Therapy: The History, Efficacy, and Adverse Effects in Clinical Practice transfusion was obstetrical hemorrhage. Blood banking was initiated in Russia and the first blood bank in the United States was at Chicago’s Cook County Hospital in 1937. These whole blood transfusions were, for the most part hemostatic. Dr. Jose Antonio Grifos Lucas pioneered the technique of aphe作者: 鐵砧 時(shí)間: 2025-3-22 17:58
Allogeneic Blood Transfusion: Complications and Side Effects that is transfused, the patient is at risk of multiple types of complications, which vary greatly in terms of frequency and severity. As a result of exquisitely sensitive testing, the incidence transmission of hepatitis and HIV from transfusion has been reduced to near zero. Conversely, the inciden作者: 我正派 時(shí)間: 2025-3-22 23:25 作者: 緯度 時(shí)間: 2025-3-23 03:14
Nitric Oxide and Hemoglobin: Physiological Implicationsn the formation of nitrate when hemoglobin is oxygenated. This is referred to as the dioxygenation reaction. Because nitrate is biologically inert at the concentrations reached during the dioxygenation reaction, it was thought that hemoglobin would only inhibit NO signaling. However, hemoglobin can 作者: Indigence 時(shí)間: 2025-3-23 06:26 作者: 卡死偷電 時(shí)間: 2025-3-23 10:56 作者: 預(yù)防注射 時(shí)間: 2025-3-23 17:54 作者: ANNUL 時(shí)間: 2025-3-23 19:22
Complications of HBOCs Including Clinical Safety Issuesization in human patients has been complicated by various factors such as differences in the products, failed clinical trials, differences in interpretation of study results and safety issues. This chapter will review the side effects and safety profiles of HBOC-related products, such as HemAssist, 作者: 撕裂皮肉 時(shí)間: 2025-3-23 23:55
On the Oxidative Toxicity of Hemoglobinds oxygen. Autoxidation of Hb however, is relatively controlled during circulation and the level of accumulated oxidized Hb in RBCs is maintained at less than 3% of total Hb due to the action of endogenous antioxidant proteins. However, during the aging process and in disease states, such as hemoglo作者: 畸形 時(shí)間: 2025-3-24 02:28 作者: alliance 時(shí)間: 2025-3-24 10:31
Perfluorocarbon-Based Oxygen Carriersased. Both provide oxygen transport to tissues. For several decades, perfluorocarbons have been explored as oxygen carriers in a variety of biological applications. Perfluorocarbons are chemically and physiologically inert, have excellent temperature and storage stability, represent little to no inf作者: Intend 時(shí)間: 2025-3-24 13:30
Platelet Substitutesnt of platelet substitutes. Platelet substitutes can be divided into red cell derivatives, liposomal derivatives, and nanoparticles. Unfortunately, to date, none of these technologies have advanced far enough to be commercially viable. Instead, the development of thrombopoietic agents and drugs to f作者: output 時(shí)間: 2025-3-24 18:04
Light scattering by superionic conductors,avoidance of reactions also involved balancing expected benefit against risks inherent in transfusions themselves. The threat of transfusion reactions expanded with recognition of newer entities in this category, the next threat of infectious disease transmission emerged, shocking the world by the H作者: 地名詞典 時(shí)間: 2025-3-24 19:39 作者: AVOID 時(shí)間: 2025-3-24 23:22 作者: Interstellar 時(shí)間: 2025-3-25 03:56 作者: 揮舞 時(shí)間: 2025-3-25 11:31 作者: BRAWL 時(shí)間: 2025-3-25 14:44
https://doi.org/10.1007/978-3-030-27103-9 and more recently, HBOC oxygen carrier with enhancement of both antioxidant and CO. transport functions. The early complete artificial cell were developed into PEG-lipid membrane and PEG-polylactide nano-dimension artificial rbc.作者: Gastric 時(shí)間: 2025-3-25 19:21
Reflection, Mirrors, and Kaleidoscopes,ficial or cultured erythrocytes. Erythrocyte substitutes can also be classified based on the source of hemoglobin, existence of cell membrane, and organic or inorganic oxygen carriers. Almost a century’s pursuit yielded only few products with limited clinical use in limited regions frustrated many b作者: output 時(shí)間: 2025-3-25 20:49 作者: DEAWL 時(shí)間: 2025-3-26 00:46
https://doi.org/10.1007/b138587tion secondary to the abluminal and luminal nitric oxide scavenging actions by the free hemoglobin molecules is postulated to be an underlying pathophysiology contributing to possible hypertension, reduced oxygen delivery and organ ischemia. Although HBOC manufacturers have attempted with great effo作者: 向外才掩飾 時(shí)間: 2025-3-26 05:01
Masayoshi Nakasako,Satoru Tokutomised in most commonly manufactured HBOCs unfortunately enhance Hb oxidative side reactions leading to compromised safety profiles. A lot has been learned from investigating aged, diseased RBCs, and naturally occurring mutant Hbs in vitro, as well as in animal and human studies. As a result, alternati作者: 館長 時(shí)間: 2025-3-26 12:04 作者: 松軟無力 時(shí)間: 2025-3-26 15:21
Masayoshi Nakasako,Satoru Tokutomirfluorooctyll bromide, (3) tertbutylperfluorocyclohexane, (4) dodecafluoropentane, and (5) perftoran. When combined with other blood-saving strategies, the use of perfluorocarbon-based oxygen carriers enables the performance of surgical procedures with increased blood loss while eliminating or lower作者: 不可知論 時(shí)間: 2025-3-26 19:10 作者: impaction 時(shí)間: 2025-3-26 23:36 作者: 過度 時(shí)間: 2025-3-27 02:09 作者: 吃掉 時(shí)間: 2025-3-27 05:28
The Global Burden of Anemiaed aerobic capacity, organ dysfunction, and mortality. Additionally, anemia is the leading risk factor for allogeneic red blood cell transfusion, which further contributes to patient morbidity. Despite being remarkably common, preventable, and readily treatable, anemia is often neglected by clinicia作者: aristocracy 時(shí)間: 2025-3-27 11:59 作者: projectile 時(shí)間: 2025-3-27 14:47 作者: 以煙熏消毒 時(shí)間: 2025-3-27 19:42 作者: 圍巾 時(shí)間: 2025-3-28 01:26
Classifications of Blood Substitutesficial or cultured erythrocytes. Erythrocyte substitutes can also be classified based on the source of hemoglobin, existence of cell membrane, and organic or inorganic oxygen carriers. Almost a century’s pursuit yielded only few products with limited clinical use in limited regions frustrated many b作者: Antigen 時(shí)間: 2025-3-28 02:19
Hemoglobin-Based Oxygen Carriers: Brief History, Pharmacology and Design Strategies, Review of the Mditionally, when restoration of circulating blood volume is achieved, maintenance of adequate blood pressure to ensure enough blood flow to deliver the oxygen to the microcirculation and resolving oxygen debt..This chapter will review the history of HBOCs, discuss how HBOCs have been designed and ho作者: Occupation 時(shí)間: 2025-3-28 06:28 作者: cipher 時(shí)間: 2025-3-28 12:48 作者: 異端 時(shí)間: 2025-3-28 16:21
Nanotechnology-Based Oxygen and Drug Carriersb in Hb-MP suspensions by common spectrophotometry is not possible due to the strong light scattering of the particles, but .H.O NMR relaxometry is a perfect tool for direct measurement of total Hb and MetHb concentrations in Hb-MP samples..The approach to transport not only oxygen from the lung to 作者: Seminar 時(shí)間: 2025-3-28 18:57 作者: 者變 時(shí)間: 2025-3-28 23:20 作者: 喪失 時(shí)間: 2025-3-29 03:17 作者: 言外之意 時(shí)間: 2025-3-29 09:32 作者: 捕鯨魚叉 時(shí)間: 2025-3-29 11:50 作者: 鞏固 時(shí)間: 2025-3-29 15:45
Bernard Jusserand,Manuel Cardonarrogate marker for red blood cell mass, with anemia typically being defined by a hemoglobin concentration less than 13?g/dL in adult men and less than 12?g/dL in adult, non-pregnant women. Anemia is remarkably common globally, though low- and middle-income countries bear the greatest burden. Anemia 作者: 管理員 時(shí)間: 2025-3-29 21:55
https://doi.org/10.1007/3-540-53614-0 transfusion was obstetrical hemorrhage. Blood banking was initiated in Russia and the first blood bank in the United States was at Chicago’s Cook County Hospital in 1937. These whole blood transfusions were, for the most part hemostatic. Dr. Jose Antonio Grifos Lucas pioneered the technique of aphe作者: nuclear-tests 時(shí)間: 2025-3-30 03:05
Eberhard Zirngiebl,Gernot Güntherodt that is transfused, the patient is at risk of multiple types of complications, which vary greatly in terms of frequency and severity. As a result of exquisitely sensitive testing, the incidence transmission of hepatitis and HIV from transfusion has been reduced to near zero. Conversely, the inciden作者: 核心 時(shí)間: 2025-3-30 05:11
https://doi.org/10.1007/BFb0103383tion, chemistry and biochemistry. However, clinical trials using HBOC transfusion as a treatment for hemorrhagic shock were disappointing and, at times, fatal. The problem arose from a design flaw in which the physical properties and their effects on the microcirculation were ignored..Animal hemorrh作者: 內(nèi)疚 時(shí)間: 2025-3-30 12:00
Light Scattering in Solids VIIIn the formation of nitrate when hemoglobin is oxygenated. This is referred to as the dioxygenation reaction. Because nitrate is biologically inert at the concentrations reached during the dioxygenation reaction, it was thought that hemoglobin would only inhibit NO signaling. However, hemoglobin can 作者: Ruptured-Disk 時(shí)間: 2025-3-30 13:22 作者: 原諒 時(shí)間: 2025-3-30 18:27
Reflection, Mirrors, and Kaleidoscopes,Thus, the pursuit for alternatives for human blood has continued over last 80?years. There are numerous products at various stages worldwide. For health care providers and scientific researchers to have a better understanding of blood substitutes, it is imperative that have a concise and practical c作者: POWER 時(shí)間: 2025-3-30 21:49 作者: 不怕任性 時(shí)間: 2025-3-31 03:41
https://doi.org/10.1007/b138587ization in human patients has been complicated by various factors such as differences in the products, failed clinical trials, differences in interpretation of study results and safety issues. This chapter will review the side effects and safety profiles of HBOC-related products, such as HemAssist, 作者: 項(xiàng)目 時(shí)間: 2025-3-31 07:05