標(biāo)題: Titlebook: Biophysics and Structure to Counter Threats and Challenges; Joseph D. Puglisi,Manolia V. Margaris Conference proceedings 2013 Springer Sci [打印本頁(yè)] 作者: 方言 時(shí)間: 2025-3-21 19:37
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書(shū)目名稱(chēng)Biophysics and Structure to Counter Threats and Challenges讀者反饋
書(shū)目名稱(chēng)Biophysics and Structure to Counter Threats and Challenges讀者反饋學(xué)科排名
作者: 交響樂(lè) 時(shí)間: 2025-3-21 21:36
System-Specific Scoring Functions: Application to Guanine-Containing Ligands and Thrombin, details of protein functioning and in drug design. Nevertheless, modern docking algorithms are still far from perfection. Development of scoring functions aimed at prediction of spatial structure and free energy of binding for molecular complexes remains a challenging task. With increasing amount o作者: ABOUT 時(shí)間: 2025-3-22 02:38 作者: arsenal 時(shí)間: 2025-3-22 07:46
Structures of Novel HIV-Inactivating Lectins,PFA, using NMR spectroscopy and X-ray crystallography. We solved crystal structures of these proteins, free and complexed with α3,α6-mannopentaose, the minimal mannosyl oligosaccharide substructure of the gp120-attached mannoses that is recognized by these lectins. Our data provide the first atomic 作者: 綁架 時(shí)間: 2025-3-22 09:12 作者: Frenetic 時(shí)間: 2025-3-22 16:38
An Introduction to Macromolecular Crystallography Through Parable and Analogy, any electromagnetic radiation such as light. But, to make the example more concrete, let’s assume it is an invisible, cream colored, 1984 Alpha Romeo Spider (curiously, exactly like the author’s). If we have never seen such a glorious object before, how can we learn of its structure? How can we vis作者: 缺乏 時(shí)間: 2025-3-22 20:16 作者: SLING 時(shí)間: 2025-3-23 00:58
Approaches to Protein-Ligand Structure Determination by NMR Spectroscopy: Applications in Drug Bindvide structural information relatively easily. For example, chemical shift mapping has been a tool employed for many years to identify ligand binding sites and to determine the stoichiometry and affinity of ligand binding. However, the determination of a high resolution solution structure of a targe作者: 聯(lián)合 時(shí)間: 2025-3-23 02:07
How Do Nascent Proteins Emerge from the Ribosome?,ctacular architecture and inherent mobility, allowing their smooth performance in decoding the genetic information as well as the formation of peptide bonds, elongation of the newly born proteins and their protection (for review see [45] ChemBioChem 10:63–72, 2009).作者: SEEK 時(shí)間: 2025-3-23 06:37 作者: Filibuster 時(shí)間: 2025-3-23 10:43 作者: cleaver 時(shí)間: 2025-3-23 14:38
1874-6500 This ASI brought together a diverse group of experts who span virology, biology, biophysics, chemistry, physics and engineering. ?Prominent lecturers representing world renowned scientists from nine (9) different countries, and students from around the world representing eighteen (18) countries, par作者: overhaul 時(shí)間: 2025-3-23 19:33 作者: arcane 時(shí)間: 2025-3-24 02:15
Structures of Novel HIV-Inactivating Lectins,e minimal mannosyl oligosaccharide substructure of the gp120-attached mannoses that is recognized by these lectins. Our data provide the first atomic details of how the core epitope of Man-9 is recognized by the OAA-class of lectins.作者: 天氣 時(shí)間: 2025-3-24 04:42
Later Victorian Britain, 1867-1900ent discrimination parameter. When the theory is applied to the example of prokaryote transcription, it is shown that the discard parameter, composed by experimentally well-defined values, induces a large template sequence dependent error rate variation.作者: Frenetic 時(shí)間: 2025-3-24 08:40 作者: mighty 時(shí)間: 2025-3-24 11:42
Large DNA Template Dependent Error Variation During Transcription,ent discrimination parameter. When the theory is applied to the example of prokaryote transcription, it is shown that the discard parameter, composed by experimentally well-defined values, induces a large template sequence dependent error rate variation.作者: debble 時(shí)間: 2025-3-24 18:22
Using NMR to Determine the Conformation of the HIV Reverse Transcription Initiation Complex,tRNA at the 5′ end, while maintaining the anticodon loop for potential loop-loop interactions. HIV RNA forms an intramolecular helix adjacent to the intermolecular primer helix. This helix, which must be broken by reverse transcription, likely acts as a kinetic block to reverse translation.作者: 永久 時(shí)間: 2025-3-24 22:02 作者: concubine 時(shí)間: 2025-3-25 01:22
Joseph Chamberlain: a Reassessment,f structural data, creation of precise system-specific scoring functions becomes possible. This article describes the physical phenomena underlying efficiency of such scoring functions and demonstrates the related quantitative approaches by the examples of guanine-containing ligands and thrombin.作者: 獨(dú)白 時(shí)間: 2025-3-25 04:36 作者: 感情 時(shí)間: 2025-3-25 11:01 作者: 最高峰 時(shí)間: 2025-3-25 14:12
Macromolecular Models by Single Molecule FRET,e attached, a three-dimensional model of the system can be determined by docking calculations. Here we discuss recent applications of single molecule FRET to obtain a model of the synaptotagmin-1:SNARE complex and to study the conformation of PSD-95.作者: Intend 時(shí)間: 2025-3-25 16:16 作者: cipher 時(shí)間: 2025-3-25 22:42
1874-6500 that multifaceted approaches and new technologies are needed to solve the biological challenges of our time.? The course succeeded in training a new generation of biologists and chemists who will probe the molecular basis for life and disease. .978-94-007-4925-2978-94-007-4923-8Series ISSN 1874-6500 Series E-ISSN 1874-6535 作者: affinity 時(shí)間: 2025-3-26 02:52 作者: 文件夾 時(shí)間: 2025-3-26 06:00
Course Abstracts,loidogenic disease formation. We also crystallized Nb484 alone and collected a complete dataset at high resolution (1.2 ?). Our experiments suggest that the nanobodies can be used as a molecular tool by helping the crystallization and by inhibiting the PrP. to PrP. transition.作者: 去才蔑視 時(shí)間: 2025-3-26 09:36 作者: 變化無(wú)常 時(shí)間: 2025-3-26 16:27
Biophysics and Structure to Counter Threats and Challenges作者: 干涉 時(shí)間: 2025-3-26 20:52
https://doi.org/10.1007/978-3-031-38813-2f fluorescent dyes at specific sites in the macromolecule. Multiple such experiments can be performed with different labeling site combinations in order to map complex conformational changes or interactions between multiple molecules. Distances that are derived from such experiments can be used for 作者: remission 時(shí)間: 2025-3-26 21:52 作者: 元音 時(shí)間: 2025-3-27 01:23
Later Victorian Britain, 1867-1900s is of particular importance to polymerization reactions with a template sequence, like transcription, translation and replication. A theoretical framework for the analysis of accuracy control is presented, including initial substrate selection and kinetic proofreading. This framework allows for an作者: 苦笑 時(shí)間: 2025-3-27 09:14 作者: 符合你規(guī)定 時(shí)間: 2025-3-27 12:16
Thoracic MIS Retropleural Access can be estimated in biological macromolecules. This has provided significant structural and dynamic information of DNA and RNA molecules. It has even been able to allow us to observe the catalytic function of a ribozyme in real time.作者: COST 時(shí)間: 2025-3-27 14:39
Todd D. Vogel,Praveen V. Mummaneni any electromagnetic radiation such as light. But, to make the example more concrete, let’s assume it is an invisible, cream colored, 1984 Alpha Romeo Spider (curiously, exactly like the author’s). If we have never seen such a glorious object before, how can we learn of its structure? How can we vis作者: 豐滿(mǎn)中國(guó) 時(shí)間: 2025-3-27 18:39
Lateral Transpsoas Retractor Technologyl. Viral reverse transcriptase (RT) initiates from a specific RNA-RNA complex formed between a host transfer RNA (tRNA.) and region at the 5′end of genomic RNA; the 3′ end of the tRNA acts as a primer for reverse transcription of genomic RNA. We determined the secondary structure of the 50?kDa compl作者: 自戀 時(shí)間: 2025-3-27 21:57 作者: APO 時(shí)間: 2025-3-28 04:59 作者: 亂砍 時(shí)間: 2025-3-28 08:01
Lateral Alignment of Epitaxial Quantum Dotsovine and scrapie in sheep). The structural investigation of prions is challenging due to the protein intrinsic disorder (mostly located in the N-terminal region). We used PrP specific nanobodies derived from Camelid antibodies to determine the structure of full-length mouse PrP. (23–230) by x-ray c作者: sterilization 時(shí)間: 2025-3-28 12:05
Fluorescence Resonance Energy Transfer Studies of Structure and Dynamics in Nucleic Acids, can be estimated in biological macromolecules. This has provided significant structural and dynamic information of DNA and RNA molecules. It has even been able to allow us to observe the catalytic function of a ribozyme in real time.作者: 相信 時(shí)間: 2025-3-28 15:57 作者: 飛來(lái)飛去真休 時(shí)間: 2025-3-28 19:53 作者: 占卜者 時(shí)間: 2025-3-29 02:09
Joseph D. Puglisi,Manolia V. MargarisMolecular dynamics and other computational approaches.Translational mechanisms and antibiotics.Structure-based drug design in biotechnology作者: jocular 時(shí)間: 2025-3-29 04:35
