標(biāo)題: Titlebook: Biophysical approaches to translational control of gene expression; Jonathan D. Dinman Book 2013 Springer Science+Business Media New York [打印本頁] 作者: emanate 時(shí)間: 2025-3-21 16:32
書目名稱Biophysical approaches to translational control of gene expression影響因子(影響力)
書目名稱Biophysical approaches to translational control of gene expression影響因子(影響力)學(xué)科排名
書目名稱Biophysical approaches to translational control of gene expression網(wǎng)絡(luò)公開度
書目名稱Biophysical approaches to translational control of gene expression網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Biophysical approaches to translational control of gene expression被引頻次
書目名稱Biophysical approaches to translational control of gene expression被引頻次學(xué)科排名
書目名稱Biophysical approaches to translational control of gene expression年度引用
書目名稱Biophysical approaches to translational control of gene expression年度引用學(xué)科排名
書目名稱Biophysical approaches to translational control of gene expression讀者反饋
書目名稱Biophysical approaches to translational control of gene expression讀者反饋學(xué)科排名
作者: 相反放置 時(shí)間: 2025-3-21 20:45 作者: 細(xì)胞膜 時(shí)間: 2025-3-22 04:28 作者: 下級(jí) 時(shí)間: 2025-3-22 05:54
Structural Analyses of the Ribosome by Chemical Modification Methods,to both RNA structure and dynamics. This chapter describes past and current methods of performing structural analysis of RNA using chemical modification techniques. We explore both radioactive and nonradioactive methodologies, a variety of reagents available to probe for different types of informati作者: 親愛 時(shí)間: 2025-3-22 09:45
Methods for Studying the Interactions of Translation Factors with the Ribosome, decades toward this goal. Cross-linking and footprinting were among the first methods used to probe the interactions of translation factors with the ribosome and the structures of ribosomal complexes. Since publication of the first high-resolution structures, these methods have continued to provide作者: 不透氣 時(shí)間: 2025-3-22 13:45
Riboproteomic Approaches to Understanding IRES Elements,t initiation mechanism that operates in the vast majority of mRNAs and the internal ribosome entry site (IRES)-dependent mechanism. IRES elements, first discovered in picornaviruses, are .-acting RNA sequences that form secondary and tertiary structures and recruit the translation machinery using a 作者: Ferritin 時(shí)間: 2025-3-22 17:11 作者: RENAL 時(shí)間: 2025-3-22 23:36
Investigating RNAs Involved in Translational Control by NMR and SAXS,mine molecular structure. Here, we review the use of NMR and SAXS for the structural analysis of RNA molecules, with a focus on RNAs involved in translational control. Practical considerations, experimental requirements, and data analysis are discussed. We also review a recently developed hybrid app作者: libertine 時(shí)間: 2025-3-23 04:02
,Analyses of RNA–Ligand Interactions by Fluorescence Anisotropy,s. By manipulating assay design, it is possible to extract equilibrium binding constants down to the low or even sub-nanomolar range, as well as measure reaction on- and off-rates, changes in enthalpy and entropy, and RNA-binding site size. These tools are invaluable for comparing and contrasting po作者: 障礙物 時(shí)間: 2025-3-23 09:27 作者: 內(nèi)閣 時(shí)間: 2025-3-23 09:51
A Multidisciplinary Approach to RNA Localisation,f model developmental systems mRNA localisation has been shown to play a key role in setting up embryonic axes. Furthermore, in the nervous system RNA localisation is thought to play a central role in synaptic plasticity, memory and learning. Important advances in our understanding of the mechanism 作者: Pander 時(shí)間: 2025-3-23 14:19
Virtual Screening for RNA-Interacting Small Molecules,discovery. The discovery of a broad range of important biological processes involved by RNA has increased the importance of RNA as a new drug target. To apply structure-based virtual screening methods to the discovery of RNA-binding ligands, many RNA 3D structure prediction programs and optimized do作者: strdulate 時(shí)間: 2025-3-23 21:30
,The “Fifth” RNA Nucleotide: A Role for Ribosomal RNA Pseudouridylation in Control of Gene Expressio the majority of species. The isomerization of uridine to pseudouridine on rRNA has important implications not only for ribosome structure but also for ribosome function. Structural and functional studies of both prokaryotic and eukaryotic ribosomes have revealed that pseudouridylation may regulate 作者: 事先無準(zhǔn)備 時(shí)間: 2025-3-23 22:56
Translational Control of Synaptic Plasticity and Memory, transmission in response to neuronal activity or different neuromodulators. Long-lasting activity-dependent synaptic plasticity requires new gene expression. While the role of transcription-mediated gene expression in synaptic plasticity and memory is well established, the mechanisms underlying tra作者: 裂縫 時(shí)間: 2025-3-24 02:22
Jonathan D. DinmanConsists of up-to-date and comprehensive reviews of research and relevant new imaging and structural approaches.Addresses major advances in researching cell’s molecular machinery through analytical, c作者: LAVA 時(shí)間: 2025-3-24 08:24
Biophysics for the Life Scienceshttp://image.papertrans.cn/b/image/188350.jpg作者: 鍵琴 時(shí)間: 2025-3-24 11:04
Late Cold War Literature and Culturechaea consist of a large (50S) and a small (30S) subunit, which together compose the 2.5 megadalton (MDa) 70S ribosome. Their eukaryotic counterparts are the 60S and 40S subunits and the 80S ribosome (from 3.5 MDa in lower eukaryotes to 4.5 MDa in higher). Many ribosomal key components are conserved作者: 千篇一律 時(shí)間: 2025-3-24 17:31
https://doi.org/10.1057/978-1-137-51308-3s with several translation factors and undergoes extensive conformational changes which are integral part of the translation process. Cryo-Electron Microscopy with powerful image-processing software has contributed immensely for elucidating those dynamic structural events; thereby our understanding 作者: BULLY 時(shí)間: 2025-3-24 20:36
https://doi.org/10.1007/978-3-030-56454-4hesis. Single molecule studies yield time-resolved measurements with low spatial resolution. Currently, there is no experimental technique capable of producing time-resolved trajectories of the ribosome with atomistic resolution. Computer simulations are critical for furthering our understanding of 作者: Postulate 時(shí)間: 2025-3-25 01:20 作者: Functional 時(shí)間: 2025-3-25 06:27
https://doi.org/10.1007/978-94-007-5491-1 decades toward this goal. Cross-linking and footprinting were among the first methods used to probe the interactions of translation factors with the ribosome and the structures of ribosomal complexes. Since publication of the first high-resolution structures, these methods have continued to provide作者: 心胸狹窄 時(shí)間: 2025-3-25 10:35 作者: Prosaic 時(shí)間: 2025-3-25 13:42
Ionizing Radiation and the Endothelium,olecular assemblages. The use of those techniques has proven to be crucial in deciphering mechanisms of translation. To date, essentially every step of protein synthesis has been probed by rapid kinetic techniques. Understanding the functional mechanisms required specific methods to determine the ti作者: 逗它小傻瓜 時(shí)間: 2025-3-25 19:25
Normal Tissue TNM Toxicity Taxonomy,mine molecular structure. Here, we review the use of NMR and SAXS for the structural analysis of RNA molecules, with a focus on RNAs involved in translational control. Practical considerations, experimental requirements, and data analysis are discussed. We also review a recently developed hybrid app作者: 火車車輪 時(shí)間: 2025-3-25 20:06
Neurological Complications in Adultss. By manipulating assay design, it is possible to extract equilibrium binding constants down to the low or even sub-nanomolar range, as well as measure reaction on- and off-rates, changes in enthalpy and entropy, and RNA-binding site size. These tools are invaluable for comparing and contrasting po作者: VALID 時(shí)間: 2025-3-26 00:11 作者: geriatrician 時(shí)間: 2025-3-26 05:06 作者: 鋼筆記下懲罰 時(shí)間: 2025-3-26 08:51
Neurological Complications in Childrendiscovery. The discovery of a broad range of important biological processes involved by RNA has increased the importance of RNA as a new drug target. To apply structure-based virtual screening methods to the discovery of RNA-binding ligands, many RNA 3D structure prediction programs and optimized do作者: 易受騙 時(shí)間: 2025-3-26 16:24 作者: 整理 時(shí)間: 2025-3-26 18:33 作者: Diaphragm 時(shí)間: 2025-3-26 22:48
978-1-4899-8709-9Springer Science+Business Media New York 2013作者: 執(zhí) 時(shí)間: 2025-3-27 03:47
X-Ray Analysis of Prokaryotic and Eukaryotic Ribosomes,s of the bacterial ribosome in different functional states (Frank et al. 1995; Stark et al. 1997a, b; Agrawal et al. 1998). However, not until the X-ray crystallographic structures of the entire 70S ribosome as well as the individual 30S and 50S subunits began to emerge did accurate atomic models be作者: Firefly 時(shí)間: 2025-3-27 05:59
Methods for Studying the Interactions of Translation Factors with the Ribosome,oteins but not about their ribosomal position will not be discussed, while X-ray crystallography and Cryo-EM are described in . and ., respectively. Special emphasis is given to directed hydroxyl radical probing, since this approach can provide not only information about the overall binding site of 作者: SOB 時(shí)間: 2025-3-27 12:44
,Analyses of RNA–Ligand Interactions by Fluorescence Anisotropy,ion mechanisms and discuss statistical validation methods. Finally, we have included sections on the use of plate readers for measuring fluorescence anisotropy across large numbers of samples and their application to high-throughput drug screening. Fluorescence anisotropy has been used to elucidate 作者: 令人苦惱 時(shí)間: 2025-3-27 14:14
A Multidisciplinary Approach to RNA Localisation,ification of the binding preferences of .-acting factors by cross-linking and immunoprecipitation and NMR-based approaches as well as the computational prediction of RNA secondary and tertiary structure combined with the use of super-resolution microscopy methods. Moreover, molecular modelling and c作者: 頭腦冷靜 時(shí)間: 2025-3-27 18:16 作者: 輕浮思想 時(shí)間: 2025-3-27 22:31
Biophysical approaches to translational control of gene expression作者: reserve 時(shí)間: 2025-3-28 04:16 作者: 錯(cuò)誤 時(shí)間: 2025-3-28 09:33
Late Cold War Literature and Cultures of the bacterial ribosome in different functional states (Frank et al. 1995; Stark et al. 1997a, b; Agrawal et al. 1998). However, not until the X-ray crystallographic structures of the entire 70S ribosome as well as the individual 30S and 50S subunits began to emerge did accurate atomic models be作者: Engulf 時(shí)間: 2025-3-28 11:30 作者: Critical 時(shí)間: 2025-3-28 16:07 作者: 陰險(xiǎn) 時(shí)間: 2025-3-28 19:40 作者: 華而不實(shí) 時(shí)間: 2025-3-28 23:31 作者: FEMUR 時(shí)間: 2025-3-29 05:03 作者: 用手捏 時(shí)間: 2025-3-29 09:59 作者: Small-Intestine 時(shí)間: 2025-3-29 15:26 作者: anus928 時(shí)間: 2025-3-29 16:43
Structural Analyses of the Ribosome by Chemical Modification Methods,on techniques. We explore both radioactive and nonradioactive methodologies, a variety of reagents available to probe for different types of information, and new methodologies that enable interrogation of large RNAs found in ribosomes and viruses.作者: maudtin 時(shí)間: 2025-3-29 21:01 作者: 狗舍 時(shí)間: 2025-3-30 03:57
https://doi.org/10.1057/978-1-137-51308-3al functions are fundamental to our existence. In this chapter we briefly discussed the cryo-EM process and its application on the translation research and highlighted many of the exciting findings revealed through it.作者: 不要嚴(yán)酷 時(shí)間: 2025-3-30 04:54
https://doi.org/10.1007/978-94-007-5491-1factors (ITAFs). RNA-binding proteins are pivotal regulators of gene expression, including internal initiation of translation, in response to numerous stresses. This chapter discusses recent advances on riboproteomic approaches aimed to identify ITAFs and the relationship between RNA–protein interaction and IRES activity.作者: Amorous 時(shí)間: 2025-3-30 09:43 作者: 變量 時(shí)間: 2025-3-30 15:09
