標(biāo)題: Titlebook: Biophysical and Computational Tools in Drug Discovery; Anil Kumar Saxena Book 2021 The Editor(s) (if applicable) and The Author(s), under [打印本頁] 作者: FAD 時間: 2025-3-21 16:46
書目名稱Biophysical and Computational Tools in Drug Discovery影響因子(影響力)
書目名稱Biophysical and Computational Tools in Drug Discovery影響因子(影響力)學(xué)科排名
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書目名稱Biophysical and Computational Tools in Drug Discovery網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Biophysical and Computational Tools in Drug Discovery被引頻次
書目名稱Biophysical and Computational Tools in Drug Discovery被引頻次學(xué)科排名
書目名稱Biophysical and Computational Tools in Drug Discovery年度引用
書目名稱Biophysical and Computational Tools in Drug Discovery年度引用學(xué)科排名
書目名稱Biophysical and Computational Tools in Drug Discovery讀者反饋
書目名稱Biophysical and Computational Tools in Drug Discovery讀者反饋學(xué)科排名
作者: cardiopulmonary 時間: 2025-3-21 22:37 作者: Blazon 時間: 2025-3-22 02:37
Role of Mass Spectrometry in Modern Herbal Drug Research,re describing the applications. Coupling GC or LC with MS results in separation of the components prior to detection by MS resulting in enhanced sensitivity and specificity. The two approaches for metabolite analysis are: (1) targeted analysis of one or two marker compounds and (2) untargeted analys作者: 手勢 時間: 2025-3-22 07:56 作者: Arthr- 時間: 2025-3-22 09:45
Relativistic Quantum Chemical and Molecular Dynamics Techniques for Medicinal Chemistry of Bioinorgrugs for tuberculosis. We have also considered a variety of actinide complexes of interest in predictive toxicology and environmental bioremediation elucidating detailed mechanisms of interactions of uranyl and plutonyl ions with human serum protein transferrin and related microbial complexes of act作者: INERT 時間: 2025-3-22 15:53 作者: obnoxious 時間: 2025-3-22 19:48 作者: 六個才偏離 時間: 2025-3-23 00:09 作者: ANA 時間: 2025-3-23 03:53
Ligand- and Structure-Based Virtual Screening in Drug Discovery,ormation of the active chemical space helps in making reasonable decisions for the ligand selection. However, the limitations in scoring functions and incorrect pose prediction may result in the inaccurate SB models of limited performance in VS experiments. Various factors interplay in the developme作者: LANCE 時間: 2025-3-23 09:25
A Rapid Computational Screening of Millions of Molecules to Identify Sequence-Specific DNA Minor GrSDD (.pid .creening of .NA-.rug) is one such utility which utilizes physicochemical properties associated with DNA as well as groove binders to rapidly scan a large library of molecules. The methodology is developed using 30 DNA-drug complexes (.?=?0.85) and, when tested on 18 DNA-drug complexes, yi作者: 業(yè)余愛好者 時間: 2025-3-23 13:25
Probing with Pharmacophore Modeling the Chloroquine Resistance and Designing Novel Antimalarials,as been illustrated and further optimized to a CQ model which is used to screen novel antimalarial inhibitors. Along with CQ, Artemisinin analogs are also used for pharmacophore modeling and additive pharmacophore modeling has been implemented for novel antimalarials designing. We have discussed and作者: chandel 時間: 2025-3-23 14:11
Culture in the Age of Death Drive, unwanted surprises and contributing to our understanding of drug action..Here we outline the factors which contribute to the establishment of successful kinetic tracer-based screening assay using homogeneous TR-FRET technology. We provide specific guidance on optimising assay signal-to-noise and ex作者: 懦夫 時間: 2025-3-23 22:05
Maria-Daniella Dick,Robbie McLaughlanre describing the applications. Coupling GC or LC with MS results in separation of the components prior to detection by MS resulting in enhanced sensitivity and specificity. The two approaches for metabolite analysis are: (1) targeted analysis of one or two marker compounds and (2) untargeted analys作者: 斥責(zé) 時間: 2025-3-24 00:45 作者: 懶洋洋 時間: 2025-3-24 04:07 作者: 前面 時間: 2025-3-24 06:39
Wen-Yu Wu,Lawrence J. Flynn,Zhu-Ding Qiueployed to confront sudden disease outbreaks. These alternative vaccines are now also being tested against tumors and hence it can be expected that in the near future they can provide a cure for or protection against cancer too. Designing peptide vaccines comprises a careful analysis of the protein 作者: critique 時間: 2025-3-24 14:07
Xiaofeng Xu,Qiang Li,Lawrence J. Flynnand chemical knowledge. A spectacular example was the use of a combination of AI generative techniques and reinforcement learning by the biotechnology company, Insilico Medicine, to successfully create new DDR1 kinase inhibitors to treat fibrosis in only 21?days. We will describe how reinforcement l作者: Offstage 時間: 2025-3-24 17:38
Xiaofeng Xu,Qiang Li,Lawrence J. Flynnous neural networks, have been developed in the past decades. They are widely applied for the design of novel compounds with required biological activity based on the analysis of chemical compounds with known antiviral activity (ligand-based design) and using the known three-dimensional structures o作者: 沉積物 時間: 2025-3-24 20:45
Biostratigraphy and the Yushe Basin,ormation of the active chemical space helps in making reasonable decisions for the ligand selection. However, the limitations in scoring functions and incorrect pose prediction may result in the inaccurate SB models of limited performance in VS experiments. Various factors interplay in the developme作者: 小樣他閑聊 時間: 2025-3-25 00:11
Neil D. Opdyke,Kainian Huang,R. H. TedfordSDD (.pid .creening of .NA-.rug) is one such utility which utilizes physicochemical properties associated with DNA as well as groove binders to rapidly scan a large library of molecules. The methodology is developed using 30 DNA-drug complexes (.?=?0.85) and, when tested on 18 DNA-drug complexes, yi作者: irradicable 時間: 2025-3-25 05:24 作者: Certainty 時間: 2025-3-25 08:37
1862-2461 virtual screening techniques in drug discovery research. Given its scope, the book is a valuable resource for students, researchers and professionals frompharmaceutical industry interested in drug design and discovery..978-3-030-85283-2978-3-030-85281-8Series ISSN 1862-2461 Series E-ISSN 1862-247X 作者: 熄滅 時間: 2025-3-25 13:23 作者: WITH 時間: 2025-3-25 19:41 作者: 防水 時間: 2025-3-25 21:16
Culture in the Age of Death Drive,e of agonists. Kinetic selectivity has been linked to fewer off-target side effects and improved efficacy, two critical aspects of compound action that can contribute to the success or failure of a drug in the clinic. Detailed mechanism of action studies is too often initiated in the later stages of作者: GREEN 時間: 2025-3-26 03:18
Maria-Daniella Dick,Robbie McLaughlanheir relatively low cost without side effects, unlike modern medicine. The efficacy of the herbal drug depends on the quality of the plants and their phytoconstituents which, in turn, depend on the species of the plant and environmental conditions under which they grow. Adulteration is also a contri作者: Aids209 時間: 2025-3-26 07:19 作者: Cougar 時間: 2025-3-26 09:25
Late Cenozoic Climate Change in Asiat to bioinorganic compounds and chelates. We consider transition metal complexes of interest for therapeutic interventions of Alzheimer’s disease and several forms of cancer, especially ovarian and breast cancers. Hence transition metal complexes of curcumin, several analogs of cisplatin, and other 作者: 時代錯誤 時間: 2025-3-26 13:14 作者: 失望未來 時間: 2025-3-26 17:24
Xiaofeng Xu,Qiang Li,Lawrence J. Flynnill challenging for researchers to find the most promising candidates among the vast number of synthesizable compounds in a reasonable time. Moreover, although molecules are picked for their predicted bioactivities, their absorption, distribution, metabolism, excretion, and toxicity (ADMET) properti作者: 的事物 時間: 2025-3-26 22:13
Xiaofeng Xu,Qiang Li,Lawrence J. Flynnase of virus transmission provides the rapid spread of viruses among people and results in a high social significance of viral infections..Computational approaches have a significant impact on the design of new drug-like compounds which may become the inhibitors of viral protein targets. Currently, 作者: opprobrious 時間: 2025-3-27 02:21 作者: 貞潔 時間: 2025-3-27 08:03 作者: Psychogenic 時間: 2025-3-27 13:15 作者: 整潔漂亮 時間: 2025-3-27 16:19 作者: 吞噬 時間: 2025-3-27 21:42 作者: kindred 時間: 2025-3-28 00:38 作者: 熱心助人 時間: 2025-3-28 03:58
Book 2021applied to peptide vaccines using novel mathematical descriptors and structure and ligand-based virtual screening techniques in drug discovery research. Given its scope, the book is a valuable resource for students, researchers and professionals frompharmaceutical industry interested in drug design and discovery..作者: HAIRY 時間: 2025-3-28 09:59 作者: 極少 時間: 2025-3-28 12:12 作者: 關(guān)心 時間: 2025-3-28 16:30
Kinetic Profiling of Ligands and Fragments Binding to GPCRs by TR-FRET,e of agonists. Kinetic selectivity has been linked to fewer off-target side effects and improved efficacy, two critical aspects of compound action that can contribute to the success or failure of a drug in the clinic. Detailed mechanism of action studies is too often initiated in the later stages of作者: 孤僻 時間: 2025-3-28 19:33
Role of Mass Spectrometry in Modern Herbal Drug Research,heir relatively low cost without side effects, unlike modern medicine. The efficacy of the herbal drug depends on the quality of the plants and their phytoconstituents which, in turn, depend on the species of the plant and environmental conditions under which they grow. Adulteration is also a contri作者: Aspiration 時間: 2025-3-29 01:48 作者: 預(yù)兆好 時間: 2025-3-29 05:42
Relativistic Quantum Chemical and Molecular Dynamics Techniques for Medicinal Chemistry of Bioinorgt to bioinorganic compounds and chelates. We consider transition metal complexes of interest for therapeutic interventions of Alzheimer’s disease and several forms of cancer, especially ovarian and breast cancers. Hence transition metal complexes of curcumin, several analogs of cisplatin, and other
