標(biāo)題: Titlebook: Biomarkers for Preclinical Alzheimer’s Disease; Robert Perneczky Book 2018 Springer Science+Business Media, LLC 2018 Epidemiology.imaging. [打印本頁] 作者: cherub 時(shí)間: 2025-3-21 18:11
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書目名稱Biomarkers for Preclinical Alzheimer’s Disease讀者反饋
書目名稱Biomarkers for Preclinical Alzheimer’s Disease讀者反饋學(xué)科排名
作者: intercede 時(shí)間: 2025-3-21 21:24
Epidemiology and Risk Factors of Alzheimer’s Disease: A Focus on Dietetween two antagonist pathways: an accumulation of lesions in the brain (evolving progressively over decades), balanced by a variety of cellular and tissular compensatory mechanisms. Preclinical research has indicated that several nutritional factors have the potential to modulate many components of作者: Glucocorticoids 時(shí)間: 2025-3-22 03:19 作者: Microaneurysm 時(shí)間: 2025-3-22 05:48
Deriving and Testing the Validity of Cognitive Reserve Candidates to some version of CR as a collection of subject factors that influence cognitive performance beyond simple brain structural health. We give a simple but precise analytic recipe to test requirements for any plausible cognitive reserve candidate based on brain imaging. Gradations of partial fulfillm作者: 寬容 時(shí)間: 2025-3-22 09:42
Methods for Pathological Classification of Alzheimer’s Diseaseil threads consisting of hyperphosphorylated tau, extracellular parenchymal amyloid β plaques, and neuritic plaques. In this chapter, we describe the neuropathological criteria for the neuropathological diagnosis of Alzheimer’s disease, as well as the fixation, processing, and histology protocols re作者: 蘑菇 時(shí)間: 2025-3-22 16:15 作者: Freeze 時(shí)間: 2025-3-22 17:42
Brain Structural Imaging in Alzheimer’s Diseasele, in particular at early stages of the disease progress, and thus not evident by visual inspection alone in magnetic resonance imaging. Group-level statistical comparisons have dominated neuroimaging studies for many years, leading to better insight into the patterns of regional vulnerability in b作者: 新陳代謝 時(shí)間: 2025-3-23 00:21 作者: 用手捏 時(shí)間: 2025-3-23 04:15 作者: anatomical 時(shí)間: 2025-3-23 06:24 作者: Collected 時(shí)間: 2025-3-23 10:51 作者: 帶傷害 時(shí)間: 2025-3-23 16:12
Soluble Amyloid Precursor Proteins in Blood: Methods and Challengesin cerebrospinal fluid do not seem to follow a consistent pattern, which limits their usefulness as diagnostic and prognostic tool. More recently, evidence has been presented for sAPP blood plasma concentration differences between patients with AD dementia and healthy control subjects. Blood can be 作者: BILK 時(shí)間: 2025-3-23 18:10
Tau Imaging in Preclinical Alzheimer’s Diseasese (AD), Parkinson’s disease without (PD) and with later dementia (PDD), Lewy body dementia (LBD), frontotemporal dementia (FTD), and corticobasal degeneration (CBD). Aggregated tau tangles, the result of hyperphosphorylation, is a pathological characteristic of a group of neurodegenerative conditio作者: 牽連 時(shí)間: 2025-3-24 00:45
Retinal Imaging in Early Alzheimer’s Diseaseges could be identified, it would contribute to a more accurate estimation of an individual’s risk of developing disease and enable the monitoring of high-risk (presymptomatic) persons as well as providing the means for assessing the efficacy of new interventions. The retina links to the visual proc作者: 表示向前 時(shí)間: 2025-3-24 04:09
In Vivo Volumetry of the Cholinergic Basal Forebrainpathogenetic aspect of Alzheimer’s disease (AD) and forms the rationale for the use of cholinomimetics as antidementive treatment. The role of the cholinergic deficit in AD pathophysiology has mainly been studied in experimental animal models and in neuropathologic examinations of human autopsy data作者: 信條 時(shí)間: 2025-3-24 09:45
Biomarkers for Preclinical Alzheimer’s Disease978-1-4939-7674-4Series ISSN 0893-2336 Series E-ISSN 1940-6045 作者: Brain-Waves 時(shí)間: 2025-3-24 13:41
https://doi.org/10.1007/978-3-642-57462-7il threads consisting of hyperphosphorylated tau, extracellular parenchymal amyloid β plaques, and neuritic plaques. In this chapter, we describe the neuropathological criteria for the neuropathological diagnosis of Alzheimer’s disease, as well as the fixation, processing, and histology protocols required for the assessment of .-. human brains.作者: PTCA635 時(shí)間: 2025-3-24 17:27 作者: vector 時(shí)間: 2025-3-24 21:39
Robert PerneczkyIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts作者: Indebted 時(shí)間: 2025-3-25 01:22 作者: 最高峰 時(shí)間: 2025-3-25 04:03 作者: 過分自信 時(shí)間: 2025-3-25 09:11 作者: Creditee 時(shí)間: 2025-3-25 13:06 作者: amenity 時(shí)間: 2025-3-25 16:31
978-1-4939-9255-3Springer Science+Business Media, LLC 2018作者: 格言 時(shí)間: 2025-3-25 21:47
https://doi.org/10.1007/978-3-8349-7177-7he aging society. Thus, dementia has been recognized by the World Health Organization as a global public health priority. Here, we briefly introduce the conceptual and methodological issues of the cost-of-illness studies (COI) of dementia, summarize the major literature regarding the economic costs 作者: 壓艙物 時(shí)間: 2025-3-26 02:43
https://doi.org/10.1007/978-3-8349-7177-7etween two antagonist pathways: an accumulation of lesions in the brain (evolving progressively over decades), balanced by a variety of cellular and tissular compensatory mechanisms. Preclinical research has indicated that several nutritional factors have the potential to modulate many components of作者: coalition 時(shí)間: 2025-3-26 05:01 作者: agnostic 時(shí)間: 2025-3-26 12:01
Wirtschaftswissenschaftliche Beitr?ge to some version of CR as a collection of subject factors that influence cognitive performance beyond simple brain structural health. We give a simple but precise analytic recipe to test requirements for any plausible cognitive reserve candidate based on brain imaging. Gradations of partial fulfillm作者: antenna 時(shí)間: 2025-3-26 14:51 作者: fluffy 時(shí)間: 2025-3-26 20:38
https://doi.org/10.1007/978-3-322-95110-6biomarkers of AD. The established cerebrospinal fluid (CSF) biomarkers of AD, reflecting both amyloidopathy and tauopathy, are being increasingly incorporated into both diagnostic guidelines, enabling the diagnosis of AD independently of clinical symptoms, and inclusionary criteria for clinical tria作者: fidelity 時(shí)間: 2025-3-26 21:59 作者: 斥責(zé) 時(shí)間: 2025-3-27 02:39
https://doi.org/10.1007/978-3-322-94349-1Alzheimer’s disease (pAD). We analyze putative models of pAD, covering both genetic and clinical aspects of pAD. Studies on cognitively healthy individuals carrying the APOE-ε4 allele and patients with mild cognitive impairment have been included. To address methodologies, studies on metabolism and 作者: 不能根除 時(shí)間: 2025-3-27 09:07
https://doi.org/10.1007/978-3-322-94349-1ddition to a description of amyloid PET itself, topics such as early and differential diagnosis of AD are discussed. Measuring amyloid in CSF as an alternative method to amyloid PET and the associations between cerebral amyloid load and the apolipoprotein E genotype are also covered in this section.作者: 濕潤(rùn) 時(shí)間: 2025-3-27 12:06 作者: Isolate 時(shí)間: 2025-3-27 17:00 作者: 迫擊炮 時(shí)間: 2025-3-27 18:47 作者: 伴隨而來 時(shí)間: 2025-3-28 01:07
Konflikthafte Vergemeinschaftungse (AD), Parkinson’s disease without (PD) and with later dementia (PDD), Lewy body dementia (LBD), frontotemporal dementia (FTD), and corticobasal degeneration (CBD). Aggregated tau tangles, the result of hyperphosphorylation, is a pathological characteristic of a group of neurodegenerative conditio作者: 單獨(dú) 時(shí)間: 2025-3-28 05:00 作者: auxiliary 時(shí)間: 2025-3-28 07:22 作者: 濃縮 時(shí)間: 2025-3-28 13:59
Book 2018e (AD). The chapters in this book are separated into five parts. Part one explores the reasons why we need improved approaches for early detection and diagnosis of AD. Part two describes clinical and research techniques for preclinical AD diagnosis. Part three looks at the current methods in use to 作者: BANAL 時(shí)間: 2025-3-28 17:19
https://doi.org/10.1007/978-3-322-94349-1s, including PET/SPECT methods, and magnetic resonance imaging (MRI) techniques, such as functional MRI (fMRI)?and arterial spin labeling (ASL), can be useful for elucidating the underlying pathophysiological changes in pAD. However, metabolic imaging with glucose PET still remains the most established FBI biomarker of pAD.作者: 笨拙的你 時(shí)間: 2025-3-28 21:44
Brain Functional Imaging in Preclinical Alzheimer’s Diseases, including PET/SPECT methods, and magnetic resonance imaging (MRI) techniques, such as functional MRI (fMRI)?and arterial spin labeling (ASL), can be useful for elucidating the underlying pathophysiological changes in pAD. However, metabolic imaging with glucose PET still remains the most established FBI biomarker of pAD.作者: SAGE 時(shí)間: 2025-3-28 23:11
0893-2336 ation advice from the experts.This volume discusses the importance of imaging, fluid, and genetic biomarkers in detecting the earliest pre-symptomatic stages of Alzheimer’s disease (AD). The chapters in this book are separated into five parts. Part one explores the reasons why we need improved appro作者: 起來了 時(shí)間: 2025-3-29 04:24 作者: 確定無疑 時(shí)間: 2025-3-29 07:35
Konflikthafte Vergemeinschaftung have been associated with an increased risk of Alzheimer’s disease, measuring this soluble protein in CSF has become a priority. This chapter demonstrates the development, optimization, and validation of a method to measure soluble TREM2 using a single reaction monitoring (SRM) targeted mass spectrometry assay.作者: 吹氣 時(shí)間: 2025-3-29 14:03 作者: 不足的東西 時(shí)間: 2025-3-29 19:29 作者: Culpable 時(shí)間: 2025-3-29 23:26
The Dimensional Structure of Subjective Cognitive Declinencept, and then we describe a procedure to measure SCD accurately. Our goal is to provide the reader with specific guidelines on how to assess and classify individuals in terms of SCD in order to identify individuals at high risk of developing cognitive impairment.作者: atopic 時(shí)間: 2025-3-30 01:25
Cerebrospinal Fluid Biomarkers of Preclinical Alzheimer’s Diseasels. The present chapter provides an overview of the clinical utility of the three established CSF AD biomarkers and covers both clinical and methodological issues. A brief summary is given on relevant laboratory techniques to determine levels of AD CSF biomarkers; methodological and clinical challenges in the field are also discussed.作者: NOCT 時(shí)間: 2025-3-30 05:23 作者: DUCE 時(shí)間: 2025-3-30 11:25
Soluble Amyloid Precursor Proteins in Blood: Methods and Challengeseasily accessed, which makes it an interesting target for biomarker discovery. This chapter presents a brief overview of sAPP in blood as a new AD biomarker candidate. Issues and challenges are discussed, both from a perspective of laboratory assessment and clinical application. A relevant technique for sAPP ascertainment is also provided.作者: CHARM 時(shí)間: 2025-3-30 15:06
Wirtschaftswissenschaftliche Beitr?gencept, and then we describe a procedure to measure SCD accurately. Our goal is to provide the reader with specific guidelines on how to assess and classify individuals in terms of SCD in order to identify individuals at high risk of developing cognitive impairment.作者: Intercept 時(shí)間: 2025-3-30 20:10
https://doi.org/10.1007/978-3-322-95110-6ls. The present chapter provides an overview of the clinical utility of the three established CSF AD biomarkers and covers both clinical and methodological issues. A brief summary is given on relevant laboratory techniques to determine levels of AD CSF biomarkers; methodological and clinical challenges in the field are also discussed.作者: 變化無常 時(shí)間: 2025-3-30 21:44
Konflikthafte Vergemeinschaftunging the issue of common source but may be somewhat imprecise in the absence of defined graphoelements such as epileptiform discharges. Connectivity analyses allow a description of interactions between brain regions, which may represent one of the earliest signs of cognitive decline.作者: PALMY 時(shí)間: 2025-3-31 01:14
Konflikthafte Vergemeinschaftungeasily accessed, which makes it an interesting target for biomarker discovery. This chapter presents a brief overview of sAPP in blood as a new AD biomarker candidate. Issues and challenges are discussed, both from a perspective of laboratory assessment and clinical application. A relevant technique for sAPP ascertainment is also provided.作者: 膽汁 時(shí)間: 2025-3-31 07:28 作者: 大都市 時(shí)間: 2025-3-31 10:55