標(biāo)題: Titlebook: Biology of Aging; Robert Zwilling,Cesare Balduini Book 1992 Springer-Verlag Berlin Heidelberg 1992 Alzheimer.alzheimer‘s disease.biology.b [打印本頁] 作者: Gram114 時(shí)間: 2025-3-21 19:01
書目名稱Biology of Aging影響因子(影響力)
書目名稱Biology of Aging影響因子(影響力)學(xué)科排名
書目名稱Biology of Aging網(wǎng)絡(luò)公開度
書目名稱Biology of Aging網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Biology of Aging被引頻次
書目名稱Biology of Aging被引頻次學(xué)科排名
書目名稱Biology of Aging年度引用
書目名稱Biology of Aging年度引用學(xué)科排名
書目名稱Biology of Aging讀者反饋
書目名稱Biology of Aging讀者反饋學(xué)科排名
作者: 上腭 時(shí)間: 2025-3-21 21:07
,Unravelling the Molecular Defect in Alzheimer’s Disease,sels as vascular amyloid of congophilic angiopathy. The cerebral amyloid protein of AD is highly insoluble, and only in recent years have suitable purification techniques been developed. In 1984, Glenner and Wong [8] described the sequence of a major component of cerebrovascular amyloid, and in 1985作者: 拋射物 時(shí)間: 2025-3-22 00:31
https://doi.org/10.1007/978-3-658-17630-3pids in the two halves of the bilayer and the topology and topography of integral proteins; in the peripheral domain, the supramolecular structure of the membrane skeleton and of its junctions with the integral domain are critical for the preservation of cell shape and deformability. It is interesti作者: gain631 時(shí)間: 2025-3-22 07:15
Spezielle VT-Implementationsprobleme,sels as vascular amyloid of congophilic angiopathy. The cerebral amyloid protein of AD is highly insoluble, and only in recent years have suitable purification techniques been developed. In 1984, Glenner and Wong [8] described the sequence of a major component of cerebrovascular amyloid, and in 1985作者: ITCH 時(shí)間: 2025-3-22 10:25
Book 1992r severalfields in which the biological research on aging is goingon. The fundamental purpose of this planning was to offerthe PhD students an advanced text that could raise thepossibility of aninterdisciplinary discussion on a wideand complex field that is very suitable to be utilized asan example 作者: 刺激 時(shí)間: 2025-3-22 15:59 作者: 把…比做 時(shí)間: 2025-3-22 20:59
an advanced text that could raise thepossibility of aninterdisciplinary discussion on a wideand complex field that is very suitable to be utilized asan example of the connection existing betweenadvancedteaching and experimental research.978-3-540-54488-3978-3-642-85789-8作者: ineffectual 時(shí)間: 2025-3-22 23:26 作者: 定點(diǎn) 時(shí)間: 2025-3-23 04:13
Stand der Normung im CCITT, Ebenen 2–6ons for this phenomenon are still poorly understood; however it has been hypothesised that neuroendocrine tissues become particularly susceptible to transformation following age-related endocrinological imbalances [5–7].作者: Monocle 時(shí)間: 2025-3-23 06:11
Heinz Burkhardt,Sigram Schindler Since the first description of this “senescence syndrome” in the early 1950s [37], senescence has been extensively investigated at the physiological, genetic, and molecular levels. Emerging from these investigations are first ideas about the molecular mechanisms controlling aging in this simple eukaryotic microorganism.作者: echnic 時(shí)間: 2025-3-23 09:51 作者: 明確 時(shí)間: 2025-3-23 15:38
Heinz Burkhardt,Sigram Schindler have no influence on cell growth (at concentrations of 1 m. or lower) nor are they mutagenic or carcinogenic. They potentiate, however, cytotoxicity and chromosomal damage induced by carcinogen treatment, e.g., alkylating agents or ionizing radiation. These and other findings led to the view that poly(ADP-ribosyl)ation plays a role in DNA repair.作者: Largess 時(shí)間: 2025-3-23 21:51 作者: 中子 時(shí)間: 2025-3-23 22:24 作者: ALIEN 時(shí)間: 2025-3-24 04:40 作者: aspect 時(shí)間: 2025-3-24 07:38 作者: 分期付款 時(shí)間: 2025-3-24 11:12 作者: 狂熱語言 時(shí)間: 2025-3-24 17:28 作者: Arrhythmia 時(shí)間: 2025-3-24 22:40
https://doi.org/10.1007/978-3-211-89012-7gs date back to the very day when they became aware of aging and death and started to bury the dead. But superstition and ignorance also have always obscured the occurrence of aging and Christoph Wilhelm Hufeland, who wrote the medical bestseller of the 18th century (“On the Art of Prolonging Human Live”, 1796 [1], rightly stated:作者: cochlea 時(shí)間: 2025-3-24 23:29 作者: 音樂會(huì) 時(shí)間: 2025-3-25 04:29
https://doi.org/10.1007/978-3-642-76462-2 protein importation. At three steps along the electron transfer chain, represented by protein-lipid enzyme complexes I, III, and IV, oxidative energy is conserved via this generation of protonic energy (Fig. 1).作者: Complement 時(shí)間: 2025-3-25 09:24
Zur Programmierung verteilter Systeme,eurofibrillary tangles, extracellular amyloid plaque cores, and cerebrovascular amyloid [7, 12, 20, 21, 23, 42–44, 46, 47]. The .A4 peptide consists of 42–43 residues and is synthesized as part of a larger precursor protein (APP, amyloid precursor protein) [16, 25, 31, 56, 63, 69].作者: Annotate 時(shí)間: 2025-3-25 13:27 作者: MURKY 時(shí)間: 2025-3-25 18:10
Age-Associated Changes of Muscarinic Cholinergic and ,-Methyl-D-Aspartate Receptors in the Mouse Br and a decreased membrane fluidity [3, 22]. Since the integrity of the neuronal membrane seems to be fundamental for most biochemical mechanisms involved in cell to cell communication like transmitter release, receptor activation, and signal transduction, many functional deficits of the aging brain can be easily explained by this hypothesis [3].作者: 平庸的人或物 時(shí)間: 2025-3-25 23:56
Aging and Electron Leakage Outside Mitochondrial Energy-Transducing Sequence, protein importation. At three steps along the electron transfer chain, represented by protein-lipid enzyme complexes I, III, and IV, oxidative energy is conserved via this generation of protonic energy (Fig. 1).作者: 細(xì)菌等 時(shí)間: 2025-3-26 03:19 作者: 長(zhǎng)處 時(shí)間: 2025-3-26 08:11
,Aging — Still a Mystery,us. Man has always followed with amazed curiosity and emotional interest the changes accompanying birth, development, aging, and death. And human beings date back to the very day when they became aware of aging and death and started to bury the dead. But superstition and ignorance also have always o作者: Stress 時(shí)間: 2025-3-26 09:50 作者: 漂白 時(shí)間: 2025-3-26 14:34 作者: 水土 時(shí)間: 2025-3-26 17:06
Membrane Processes in Human Red Cell Aging,epresent a good model for the study of how protein molecules and plasma membranes age. Human red cells spend 120 days in the circulation and are then removed in an age-dependent manner [1]. The presence of autoantibodies on the surface of senescent cells [2, 3] led to the development of the autoimmu作者: 走調(diào) 時(shí)間: 2025-3-26 22:24
Aging and Electron Leakage Outside Mitochondrial Energy-Transducing Sequence,ctorial translocation of protons across the inner membrane. This proton electrochemical potential (Δ.H .) drives ATP synthesis, ion translocation, and protein importation. At three steps along the electron transfer chain, represented by protein-lipid enzyme complexes I, III, and IV, oxidative energy作者: Inordinate 時(shí)間: 2025-3-27 02:46 作者: 粘連 時(shí)間: 2025-3-27 07:48
,Unravelling the Molecular Defect in Alzheimer’s Disease,creased interest in the biology of aging and in the pathology of age-associated diseases. Among these, Alzheimer’s disease (AD) is the most frequent cause of dementia and as such already the fourth leading cause of death. Its pathological basis was defined by Alois Alzheimer in 1907 in a case report作者: Glossy 時(shí)間: 2025-3-27 10:27
,Expression of Alzheimer’s Amyloid Gene in Development, Aging, and Alzheimer’s Disease,is correlated with massive deposition of fibrillar aggregates of the amyloid .A4 protein. These amyloid deposits occur in the brain as intracellular neurofibrillary tangles, extracellular amyloid plaque cores, and cerebrovascular amyloid [7, 12, 20, 21, 23, 42–44, 46, 47]. The .A4 peptide consists o作者: adequate-intake 時(shí)間: 2025-3-27 16:49
Aging Brain and Hypothalamic-Pituitary-Adrenal Function: Implications for Dementia of the Alzheimerally work at a sufficient level but fail to respond adequately to any further environmental demand [1]. Age primarily affects brain function: impaired cognition represents a common feature of late life, readily encountered in clinical practice.作者: Frequency 時(shí)間: 2025-3-27 19:42 作者: 積習(xí)難改 時(shí)間: 2025-3-27 23:56
Arteriosclerosis and Aging. Distribution Pattern of Atherosclerosis in Various Arteries,ge-related alterations of tissues, then arteriosclerosis seems to be an aging phenomenon [4, 11]. Since we are the only species which suffers from arteriosclerosis, it appears that this disease is a consequence of a generalized evolutionary development related to aging.作者: MAPLE 時(shí)間: 2025-3-28 03:48
Physiological and Surgical Aspects of the Geriatric Patient,ed on the one hand a progressive decrease in birth indices and on the other an increase in life expectancy. The average length of life in Italy has increased to 78 years for women and to 71 years for men. In the world, 10% of the population is over 65 years old.作者: Brocas-Area 時(shí)間: 2025-3-28 09:22 作者: Noctambulant 時(shí)間: 2025-3-28 12:11
Hormone Production in Neuroendocrine Tumours of Transgenic Mice,d of variably differentiated cells that share a number of morphologic markers normally expressed by neurons and endocrine cells [3, 4]. In laboratory animals, the occurrence of neuroendocrine tumours, which is virtually null in young animals, shows an extraordinary increase with age [5, 6]. The reas作者: 瘙癢 時(shí)間: 2025-3-28 18:38 作者: Mitigate 時(shí)間: 2025-3-28 19:36
Reihe der Villa Vigonihttp://image.papertrans.cn/b/image/187673.jpg作者: 漸變 時(shí)間: 2025-3-29 01:21
https://doi.org/10.1007/978-3-642-85789-8Alzheimer; alzheimer‘s disease; biology; brain; dementia; receptor作者: BATE 時(shí)間: 2025-3-29 05:29
978-3-540-54488-3Springer-Verlag Berlin Heidelberg 1992作者: 賞錢 時(shí)間: 2025-3-29 08:05
https://doi.org/10.1007/978-3-211-89012-7us. Man has always followed with amazed curiosity and emotional interest the changes accompanying birth, development, aging, and death. And human beings date back to the very day when they became aware of aging and death and started to bury the dead. But superstition and ignorance also have always o作者: CAMEO 時(shí)間: 2025-3-29 15:15
https://doi.org/10.1007/978-3-211-89012-7an accumulation of stochastic damage to DNA [16]. Damaged DNA is continuously repaired by several mechanisms in both proliferating and resting cells in order to avoid defective replication and abnormalities in transcription and translation [7]. One sort of such damage is the presence of uracil in DN作者: GROWL 時(shí)間: 2025-3-29 15:54 作者: 斥責(zé) 時(shí)間: 2025-3-29 23:15 作者: NICHE 時(shí)間: 2025-3-30 01:26
https://doi.org/10.1007/978-3-642-76462-2ctorial translocation of protons across the inner membrane. This proton electrochemical potential (Δ.H .) drives ATP synthesis, ion translocation, and protein importation. At three steps along the electron transfer chain, represented by protein-lipid enzyme complexes I, III, and IV, oxidative energy作者: debris 時(shí)間: 2025-3-30 05:16
M. W. Austen,J. M. Janas,H. R. Wiehlee. Several experimental models have been developed in a variety of animals to investigate the biology and pathophysiology of aging. Studies performed with them have alternatively provided evidence supporting a wide variety of different pathogenetic mechanisms. Recently, the so-called oxidative theor作者: Ondines-curse 時(shí)間: 2025-3-30 08:49
Spezielle VT-Implementationsprobleme,creased interest in the biology of aging and in the pathology of age-associated diseases. Among these, Alzheimer’s disease (AD) is the most frequent cause of dementia and as such already the fourth leading cause of death. Its pathological basis was defined by Alois Alzheimer in 1907 in a case report作者: 符合國(guó)情 時(shí)間: 2025-3-30 16:15 作者: Infusion 時(shí)間: 2025-3-30 16:44 作者: 食料 時(shí)間: 2025-3-30 20:47
Rechnerverbund Im Bildschirmtext,t in connective tissues (such as cartilage, skin, blood vessel wall) where the extracellular matrix is large and well developed. In these tissues, PGs represent the most important component of the interfibrillar ground substance and interact with collagen fibrils [1–3].作者: white-matter 時(shí)間: 2025-3-31 02:32
https://doi.org/10.1007/978-3-642-67978-0ge-related alterations of tissues, then arteriosclerosis seems to be an aging phenomenon [4, 11]. Since we are the only species which suffers from arteriosclerosis, it appears that this disease is a consequence of a generalized evolutionary development related to aging.作者: 絆住 時(shí)間: 2025-3-31 07:32 作者: Atheroma 時(shí)間: 2025-3-31 11:46
Heinz Burkhardt,Sigram Schindlerwhich uses nicotinamide-adenine dinucleotide (NAD) as substrate (for review, see [1]). The DNA-binding domain of the enzyme specifically binds to DNA single-or double-strand breaks, resulting in enzyme activation. Thus, treatment of cells with chemical or physical carcinogens induces a dose-dependen作者: conjunctivitis 時(shí)間: 2025-3-31 14:39
Stand der Normung im CCITT, Ebenen 2–6d of variably differentiated cells that share a number of morphologic markers normally expressed by neurons and endocrine cells [3, 4]. In laboratory animals, the occurrence of neuroendocrine tumours, which is virtually null in young animals, shows an extraordinary increase with age [5, 6]. The reas作者: 逢迎白雪 時(shí)間: 2025-3-31 17:37
Heinz Burkhardt,Sigram Schindler the pigmentation of the culture changes, the peripheral hyphae (filamentous “cells” of a mycelium) become slender and undulate, and the formation of aerial hyphae is drastical reduced. Some days after the first occurrence of these morphological symptoms of aging, the culture stops growing and dies.
