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標題: Titlebook: Biologics for the Treatment of Rheumatoid Arthritis; Ronald F van Vollenhoven Book 2016 Springer International Publishing Switzerland 2016 [打印本頁]

作者: 哄笑    時間: 2025-3-21 18:45
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作者: 溺愛    時間: 2025-3-21 20:29
978-3-319-13107-8Springer International Publishing Switzerland 2016
作者: 繼承人    時間: 2025-3-22 02:51
Knowledge Intensive Design Technologyutics: it became possible to design a molecule with a very specific predetermined biological effect for use in a relevant disease. Applications of the technology rapidly entered the medical fields of oncology and transplantation medicine.
作者: LATHE    時間: 2025-3-22 08:32

作者: Vasoconstrictor    時間: 2025-3-22 09:57
https://doi.org/10.1007/978-1-4615-0345-3Dozens of cytokines are involved in the inflammatory process and it stands to reason that many of them could be targeted successfully in the treatment of inflammatory diseases.
作者: puzzle    時間: 2025-3-22 15:44
Lessons Learned from Past ProjectsForty years ago this year George Kohler and Cesar Milstein published an article in . describing a method for “continuous cultures of fused cells secreting antibody of predefined specificity” Figure?10.1 [1].
作者: Concrete    時間: 2025-3-22 17:35
Novel biologics and small molecules with biologic-like effects,Dozens of cytokines are involved in the inflammatory process and it stands to reason that many of them could be targeted successfully in the treatment of inflammatory diseases.
作者: Connotation    時間: 2025-3-22 23:16

作者: adduction    時間: 2025-3-23 03:03
Ronald F van VollenhovenA practical evidence-based overview of the available and emerging biologic treatments for rheumatoid arthritis..This book also features a concise summary of the latest updates regarding biosimilars fo
作者: 一致性    時間: 2025-3-23 08:23

作者: FECT    時間: 2025-3-23 10:33
Michiko Matsuda,Yuki Naoda,Fumihiko Kimuraovial joints, which may lead to damage to the cartilage and bone and a progressive loss of function. The prevalence in Western adult populations is 0.5–1?% and it is relatively similar across Europe, North America, Asia, and South Africa. However, certain native American Indians, for example Pima In
作者: PHAG    時間: 2025-3-23 15:37
Towards Agent-Based Product Modellings are the dominant symptoms, but patients also frequently experience general symptoms due to the systemic inflammatory state. Extreme fatigue and lassitude, and even slight fever and profound weight loss are not unusual at this stage. The musculoskeletal symptoms may already in the earlier phase eng
作者: intangibility    時間: 2025-3-23 21:26
Knowledge Intensive Design Technologyutics: it became possible to design a molecule with a very specific predetermined biological effect for use in a relevant disease. Applications of the technology rapidly entered the medical fields of oncology and transplantation medicine.
作者: 得罪人    時間: 2025-3-23 22:34
Michiko Matsuda,Yuki Naoda,Fumihiko Kimuraas in the field of oncological research, where in the early 1980s it was established as the mediator of tumor-related cachexia (and because of this it was also named ‘cachectin’) and in separate lines of research it was shown to be capable of inducing necrosis of malignant cells in vitro, giving it
作者: majestic    時間: 2025-3-24 03:50

作者: 充足    時間: 2025-3-24 09:36
Scientist, Inventor, Entrepreneur?,sent in the inflamed synovium, and in some animal models T cells can be identified as the main effector cells of the inflammatory response. Moreover, the demonstration that human leukocyte antigen (HLA)-DR genotypes are associated with the risk for RA points at the T cell, because the function of th
作者: Ostrich    時間: 2025-3-24 12:20
https://doi.org/10.1007/978-1-4615-0345-3gment of the patient population had failed all available conventional agents and had ongoing moderate or severe inflammation with progressive destruction of the joints. Even though some conventional approaches using more aggressive combinations of disease-modifying antirheumatic agents (DMARDs) seem
作者: CAPE    時間: 2025-3-24 18:02

作者: adipose-tissue    時間: 2025-3-24 21:58
Overview of Biologic Therapies,utics: it became possible to design a molecule with a very specific predetermined biological effect for use in a relevant disease. Applications of the technology rapidly entered the medical fields of oncology and transplantation medicine.
作者: 流動才波動    時間: 2025-3-25 02:40
B-cell Directed Therapy,d factors as a specific marker for the disease pointed to a possible role for humoral (antibody-mediated) immunity and this was further strengthened by the discovery of anti-citrullinated peptide antibodies (ACPAs) many decades later.
作者: Arable    時間: 2025-3-25 06:32
Towards Agent-Based Product Modellingn are hallmarks of the disease that when advanced are easily recognized on plain radiographs, but that may at even earlier stages be detected through more sensitive imaging techniques such as magnetic resonance imaging (MRI) and ultrasound.
作者: 負擔    時間: 2025-3-25 11:03

作者: 貪婪性    時間: 2025-3-25 15:12

作者: 我就不公正    時間: 2025-3-25 17:07

作者: GULF    時間: 2025-3-25 20:54
Cytokine inhibitors,its current name. While its role in tumor surveillance and antitumor immunity remains of interest – and TNF is in fact approved as a treatment for certain sarcomas – the role of TNF in immunity attracted increasing interest and led to dramatic therapeutic developments.
作者: ENDOW    時間: 2025-3-26 03:12

作者: Seminar    時間: 2025-3-26 07:38

作者: Facet-Joints    時間: 2025-3-26 09:43

作者: Angioplasty    時間: 2025-3-26 14:02

作者: Urologist    時間: 2025-3-26 19:27

作者: 施魔法    時間: 2025-3-26 22:51
the latest therapeutic developments in this field. This book is an invaluable source of topical information for all rheumatologists and health care professionals treating patients with rheumatoid arthritis..978-3-319-13107-8978-3-319-13108-5
作者: insidious    時間: 2025-3-27 01:20
Michiko Matsuda,Yuki Naoda,Fumihiko Kimurae annual incidence is between 0.15 and 0.88 per 1000 and women are affected two or three times as often as men. RA occurs in all age groups with a peak of disease onset between 45 and 65?years of age [4].
作者: Inveterate    時間: 2025-3-27 08:23
Scientist, Inventor, Entrepreneur?,, it was demonstrated that the human rheumatoid synovium does not present abundant evidence for T-cell activation, and cyclosporin-A, the one conventional antirheumatic agent that is believed to work almost exclusively through inhibition of T cells, has only limited efficacy in RA.
作者: 小故事    時間: 2025-3-27 09:45
https://doi.org/10.1007/978-1-4615-0345-3imarily in patients with established and refractory disease. The effects were sometimes dramatic and often there was at least some level of success, and the enormous enthusiasm with which biologics were greeted in the field of rheumatology is readily explained by the results in these hitherto ‘untreatable’ patients.
作者: GNAT    時間: 2025-3-27 16:56
Disease overview,e annual incidence is between 0.15 and 0.88 per 1000 and women are affected two or three times as often as men. RA occurs in all age groups with a peak of disease onset between 45 and 65?years of age [4].
作者: 敵意    時間: 2025-3-27 20:31

作者: Gesture    時間: 2025-3-27 23:45

作者: RENAL    時間: 2025-3-28 03:47

作者: Handedness    時間: 2025-3-28 07:38

作者: 絆住    時間: 2025-3-28 13:19

作者: fulcrum    時間: 2025-3-28 16:58

作者: BARGE    時間: 2025-3-28 18:57
Cytokine inhibitors,as in the field of oncological research, where in the early 1980s it was established as the mediator of tumor-related cachexia (and because of this it was also named ‘cachectin’) and in separate lines of research it was shown to be capable of inducing necrosis of malignant cells in vitro, giving it
作者: 表皮    時間: 2025-3-29 02:15

作者: persistence    時間: 2025-3-29 07:00

作者: airborne    時間: 2025-3-29 08:28
Strategies for the optimal use of biologic agents in rheumatoid arthritis,gment of the patient population had failed all available conventional agents and had ongoing moderate or severe inflammation with progressive destruction of the joints. Even though some conventional approaches using more aggressive combinations of disease-modifying antirheumatic agents (DMARDs) seem
作者: BILL    時間: 2025-3-29 15:04





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