標(biāo)題: Titlebook: Biological Toxins and Bioterrorism; P. Gopalakrishnakone Living reference work 20200th edition [打印本頁(yè)] 作者: 武士精神 時(shí)間: 2025-3-21 19:23
書(shū)目名稱Biological Toxins and Bioterrorism影響因子(影響力)
書(shū)目名稱Biological Toxins and Bioterrorism影響因子(影響力)學(xué)科排名
書(shū)目名稱Biological Toxins and Bioterrorism網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Biological Toxins and Bioterrorism網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Biological Toxins and Bioterrorism被引頻次
書(shū)目名稱Biological Toxins and Bioterrorism被引頻次學(xué)科排名
書(shū)目名稱Biological Toxins and Bioterrorism年度引用
書(shū)目名稱Biological Toxins and Bioterrorism年度引用學(xué)科排名
書(shū)目名稱Biological Toxins and Bioterrorism讀者反饋
書(shū)目名稱Biological Toxins and Bioterrorism讀者反饋學(xué)科排名
作者: Obverse 時(shí)間: 2025-3-21 23:54
2542-761X nology, including topics like bioterrorism, toxin evolution In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the bioche作者: 死亡 時(shí)間: 2025-3-22 02:48
https://doi.org/10.1007/978-3-642-66938-5ylococcal enterotoxin B (SEB), and epsilon toxin of ., which are among the highest level of biothreat agents. This approach opens new avenues to combat biothreat and bioterrorism against public health and national security.作者: 延期 時(shí)間: 2025-3-22 05:06 作者: 意外的成功 時(shí)間: 2025-3-22 10:39
UICC International Union Against Cancerand physics..This chapter includes an overview of different types of antibodies and labels used as recognition elements for the elaboration of immunosensors. The most common ways to immobilize Ab on a transducer surface will be described and a description of some of the most popular transducing techniques will be given.作者: NAG 時(shí)間: 2025-3-22 16:56
Immunosensors: Using Antibodies to Develop Biosensors for Detecting Pathogens and Their Toxins,and physics..This chapter includes an overview of different types of antibodies and labels used as recognition elements for the elaboration of immunosensors. The most common ways to immobilize Ab on a transducer surface will be described and a description of some of the most popular transducing techniques will be given.作者: 輕快走過(guò) 時(shí)間: 2025-3-22 21:08
UICC International Union Against Cancerdisulfide bond to a B-chain. The B-chain facilitates internalization of the A-chain, which then exerts its toxic effects by inhibiting protein synthesis leading to cell death. These two plant toxins are highly toxic to human, and initial manifestations of ricin or abrin intoxication are generally no作者: osculate 時(shí)間: 2025-3-22 21:48 作者: 冥想后 時(shí)間: 2025-3-23 03:18
UICC International Union Against Cancerof a 100 kDa heavy chain (Hc) and a 50 kDa light chain (Lc) linked by a single disulfide bond. BoNT Hc binds to its receptors on the neural membrane and sets the stage for endocytosis at the motor nerve terminals (MNTs). Within early endosomes BoNT undergoes pH-dependent separation of the Hc and Lc.作者: 木質(zhì) 時(shí)間: 2025-3-23 08:32
https://doi.org/10.1007/978-3-642-96656-9partition into the oil extract, and there are different isoforms with varied toxicities and antigenicities. RT belongs to the B group of biological warfare agents (BWA). It is made up of two functionally different parts, an A polypeptide chain (RTA: 32 kDa) and a B polypeptide chain (RTB: 34KDa). RT作者: 神經(jīng) 時(shí)間: 2025-3-23 13:23
https://doi.org/10.1007/978-3-642-96656-9n called cholera toxin (CT) which is largely responsible for the disease. CT consists of one enzymatically active A-subunit and five immunogenic B-subunits. The B-subunits form a symmetrical pentamer into which A chain sits on the top creating a wedge-shaped structure. Both A- and B-subunits are enc作者: Factorable 時(shí)間: 2025-3-23 17:20
Natürliche Entwicklung des Krebsestein synthesis in eukaryotes by inactivating ribosomes irreversibly. The heterodimeric protein comprises of the toxic subunit, the A chain which is disulfide bonded to the B chain, a galactose-specific lectin, which helps in binding and trafficking of the toxin in cells. A single molecule of the abr作者: 沉思的魚(yú) 時(shí)間: 2025-3-23 18:06
https://doi.org/10.1007/978-3-642-96656-9 foods derived from plants can be infected by fungi during growing of the plants, harvest, and storage of the food; therefore, exposure to mycotoxins can easily occur in human populations. Researchers have special focus on mycotoxins because of their toxic effects in both animals and humans. Althoug作者: 有惡意 時(shí)間: 2025-3-23 23:25 作者: 小步舞 時(shí)間: 2025-3-24 03:47 作者: dandruff 時(shí)間: 2025-3-24 10:18
UICC International Union Against Cancerense. The word pathogen defines any disease-producing agent..With the constant progress of scientific knowledge, a fast diversification of the detection techniques is occurring, brought about by the appearance of imaginative new concepts within the scientific community. Biosensors are a perfect exam作者: 開(kāi)頭 時(shí)間: 2025-3-24 14:17
https://doi.org/10.1007/978-3-642-66938-5se biotoxins as bioterror agents, including their high potency, the relatively long latency period before symptoms are manifested, the difficulty in detecting or diagnosing their presence and identity, and their relative ease in production and stability in the environment. All of these features also作者: Glower 時(shí)間: 2025-3-24 16:25 作者: 努力趕上 時(shí)間: 2025-3-24 21:25 作者: BLANK 時(shí)間: 2025-3-25 02:39
Entwicklungsgeschichte, Anatomie, Histologiethe case of covert attacks, determining that an exposure has even occurred can be difficult due to the delayed onset of clinical signs and symptoms in affected individuals. While significant efforts have been undertaken in the past to prevent the proliferation of toxins and other biological threat a作者: 膠狀 時(shí)間: 2025-3-25 06:21
Therapie von rheumatischen Erkrankungen,isk biothreat agents by the Centers for Disease Control and Prevention (CDC). They are the causative agents of botulism, a severe neuroparalytic disease which can be fatal in the absence of medical care. While the natural cases of botulism are rare, by virtue of their extreme toxicity, easy producti作者: 祝賀 時(shí)間: 2025-3-25 08:32
Therapie von rheumatischen Erkrankungen,ulinum neurotoxin, are potential agents of biological warfare and are also increasingly being used for therapeutic and cosmetic purposes. Despite the potential damage they could cause to human health, no drugs are currently available for post-intoxication therapy. Recent progress in drug discovery e作者: Gudgeon 時(shí)間: 2025-3-25 15:38
https://doi.org/10.1007/978-3-642-97792-3 brought considerable benefits to patients, from children with cerebral palsy to older patients with stroke-related conditions. Aesthetic use alone is probably over 10 million treatments per year and rising rapidly. The latest licensed applications in pain treatment and urology are amongst a range o作者: HERE 時(shí)間: 2025-3-25 19:47
,Behandlung von Obstipation und Diarrh?,he host to invade and impair other important cellular processes. Different domains of these proteins have a number of homology groups with varying protein structure and functions. Some of them have sequence similarities across all three cellular forms of life – Bacteria, Archaea, and Eukarya – sugge作者: 揭穿真相 時(shí)間: 2025-3-25 22:12 作者: squander 時(shí)間: 2025-3-26 01:40 作者: In-Situ 時(shí)間: 2025-3-26 06:48
P. GopalakrishnakoneComplete and comprehensive overview of toxinology.Written by a very large team of experts from all around the world.Covers all areas of toxinology, including topics like bioterrorism, toxin evolution 作者: 生氣的邊緣 時(shí)間: 2025-3-26 10:48
Toxinologyhttp://image.papertrans.cn/b/image/187474.jpg作者: 陳腐的人 時(shí)間: 2025-3-26 15:31 作者: 極大的痛苦 時(shí)間: 2025-3-26 16:59 作者: 提名 時(shí)間: 2025-3-27 00:34
Botulinum Neurotoxin Antidotes,of a 100 kDa heavy chain (Hc) and a 50 kDa light chain (Lc) linked by a single disulfide bond. BoNT Hc binds to its receptors on the neural membrane and sets the stage for endocytosis at the motor nerve terminals (MNTs). Within early endosomes BoNT undergoes pH-dependent separation of the Hc and Lc.作者: Wallow 時(shí)間: 2025-3-27 01:29 作者: characteristic 時(shí)間: 2025-3-27 08:29
Structure, Genetics, and Mode of Disease of Cholera Toxin,n called cholera toxin (CT) which is largely responsible for the disease. CT consists of one enzymatically active A-subunit and five immunogenic B-subunits. The B-subunits form a symmetrical pentamer into which A chain sits on the top creating a wedge-shaped structure. Both A- and B-subunits are enc作者: 苦澀 時(shí)間: 2025-3-27 13:18 作者: 巨碩 時(shí)間: 2025-3-27 17:27
Mycotoxins, foods derived from plants can be infected by fungi during growing of the plants, harvest, and storage of the food; therefore, exposure to mycotoxins can easily occur in human populations. Researchers have special focus on mycotoxins because of their toxic effects in both animals and humans. Althoug作者: 按等級(jí) 時(shí)間: 2025-3-27 20:01
Aflatoxins, a fused dihydrofurofuran moiety which are produced by . and . fungi. AF contamination can occur in various commodities including cereals, nuts, dried fruits, cocoas, oil seeds, spices, and copras in the field and/or during storage. The toxicological consequences of AF in populations are quite varie作者: Vulvodynia 時(shí)間: 2025-3-28 01:28
Marine Biotoxins in History: Misuse and Mayhem,uicide, attempt, or successfully commit murder, and STX has been officially declared a chemical weapon by the world’s governments. This meant that it was no longer a natural marine chemical of interest to toxinologists, pharmacologists, and at times seafood producers (because it can taint their prod作者: Proponent 時(shí)間: 2025-3-28 04:27 作者: anaerobic 時(shí)間: 2025-3-28 10:05
Biosecurity and Toxins,se biotoxins as bioterror agents, including their high potency, the relatively long latency period before symptoms are manifested, the difficulty in detecting or diagnosing their presence and identity, and their relative ease in production and stability in the environment. All of these features also作者: TRUST 時(shí)間: 2025-3-28 13:04
Toxins and Food Safety,parasites, and viruses) and toxins from natural source and microorganisms. Toxins are lethal to humans and vary in severity based on their interaction to target sites. They can be either non-proteinaceous small molecule or peptides and proteins. Some important toxins derived from bacteria (e.g., bot作者: 同謀 時(shí)間: 2025-3-28 16:27
Aptamers as New Agents Against Biotoxins,t there are no effective countermeasures for most biological toxins. Aptamers are short single-stranded DNA or RNA oligonucleotides with high affinity and specificity to their targets. They are selected through the entire in vitro process and have many advantages over antibodies, leading them to hav作者: glisten 時(shí)間: 2025-3-28 21:57 作者: insurgent 時(shí)間: 2025-3-29 02:47
Basic Chemistry of Botulinum Neurotoxins Relevant to Vaccines, Diagnostics, and Countermeasures,isk biothreat agents by the Centers for Disease Control and Prevention (CDC). They are the causative agents of botulism, a severe neuroparalytic disease which can be fatal in the absence of medical care. While the natural cases of botulism are rare, by virtue of their extreme toxicity, easy producti作者: Aggregate 時(shí)間: 2025-3-29 05:18
Challenges in Developing Inhibitors Against Toxins,ulinum neurotoxin, are potential agents of biological warfare and are also increasingly being used for therapeutic and cosmetic purposes. Despite the potential damage they could cause to human health, no drugs are currently available for post-intoxication therapy. Recent progress in drug discovery e作者: CUMB 時(shí)間: 2025-3-29 08:25
Counterfeit Botulinum Medical Products and Risk of Bioterrorism, brought considerable benefits to patients, from children with cerebral palsy to older patients with stroke-related conditions. Aesthetic use alone is probably over 10 million treatments per year and rising rapidly. The latest licensed applications in pain treatment and urology are amongst a range o作者: offense 時(shí)間: 2025-3-29 11:40 作者: harangue 時(shí)間: 2025-3-29 18:13 作者: 射手座 時(shí)間: 2025-3-29 21:23 作者: 美色花錢(qián) 時(shí)間: 2025-3-30 00:32 作者: connoisseur 時(shí)間: 2025-3-30 04:51 作者: 我不重要 時(shí)間: 2025-3-30 10:42
Botulinum Toxins: A Review,epted diagnostic method for BoNTs is the mouse bioassay, which takes 4 days to complete. This clearly cannot meet the immediate need for clinical diagnosis of botulism, botulinum detection in field conditions, and screening of large scale samples. Consequently, the clinical diagnosis of botulism rel作者: 爭(zhēng)吵加 時(shí)間: 2025-3-30 13:07
Botulinum Neurotoxin Antidotes,issemination of the neurotoxin makes it as a viable biothreat agent. The quest for antidotes to treat botulism is an ongoing process. Efforts to develop antidotes against BoNTs have also advanced our knowledge about endoexocytic mechanisms that mediate BoNT signaling at the MNT. This review describe作者: 火車車輪 時(shí)間: 2025-3-30 20:01
Ricin: A Review,herapy has been evaluated. Toxicity and severity of clinical manifestations vary between different routes of administration. Inhalation is the most potent route of entry, and oral ingestion is less toxic and may be nonlethal. RT is detected in tissue sections, body fluids, and nasal swabs of poisone作者: defray 時(shí)間: 2025-3-30 23:34 作者: DEFER 時(shí)間: 2025-3-31 04:46
Abrin and Immunoneutralization: A Review, might not be useful for public at large. However, passive administration of antibodies has served as the primary mode of therapy against a large number of toxins. To date, the monoclonal antibody D6F10 is the only known neutralizing antibody reported against abrin. The antibody can rescue cells as 作者: patella 時(shí)間: 2025-3-31 08:25
Mycotoxins,as cellular signaling. Further studies are needed to elucidate complete cellular pathway of mycotoxins toxicity. More important mycotoxins including fumonisins, ochratoxins, trichothecenes, zearalenone, and patulin are discussed in this chapter with focus on toxicity and mechanisms of action in anim作者: Obituary 時(shí)間: 2025-3-31 11:13 作者: obeisance 時(shí)間: 2025-3-31 13:24
Marine Biotoxins in History: Misuse and Mayhem,ans of identifying whether a victim has been purposefully intoxicated. Treatment of intoxication by STX or TTX is still relatively crude, relying mostly upon gastric evacuation to remove unabsorbed toxin and symptomatic relief to nurse the victim through the acute phase of an intoxication and then r作者: Kidnap 時(shí)間: 2025-3-31 19:10
Biosecurity and Toxins,or passive immunization with antibodies; however, there are no postexposure therapies available after symptoms have manifested. A vigilant and robust biotoxin research community must be mobilized to not only better characterize the existing biotoxins but also to anticipate new variants or entirely n作者: 改變立場(chǎng) 時(shí)間: 2025-3-31 22:22
Toxins and Food Safety,eveloping countries. Among the majority of foodborne illness, a limited number of cases are attributed to toxin poisoning. The prevention of foodborne illness relies on good practices of food safety programs; proper handling procedure, good sanitation, and hygiene; and implication of standard food a作者: BUST 時(shí)間: 2025-4-1 03:43
The Public Health Response to Potential Toxin Bioterrorism,l of awareness and low threshold of suspicion for toxin etiologies by medical practitioners, including those in hospital emergency departments and in private practice, is necessary to recognize a biological event involving a deliberate release of toxin has occurred. Where highly sensitive and specif作者: 不可侵犯 時(shí)間: 2025-4-1 09:14 作者: Ganglion-Cyst 時(shí)間: 2025-4-1 13:22
Challenges in Developing Inhibitors Against Toxins,lly large surface area of the toxin-substrate interaction interface, the flexible loops lining the active site, involvement of a metal ion in the catalytic activity, and molten globule form of the enzyme at physiological temperature contribute to this challenge and are discussed.作者: reperfusion 時(shí)間: 2025-4-1 17:34
Counterfeit Botulinum Medical Products and Risk of Bioterrorism,ctable product. The potential for the sources of such products to become providers for bioterrorist activities is therefore of key importance. Can botulinum toxin from medical sources become a terrorist weapon? The background to this situation is discussed in detail, and the potential for such medic作者: 胎兒 時(shí)間: 2025-4-1 21:17
Evolutionary Traits of Toxins,ersity at every level, including species, individual organism, and even at the molecular level. Study of evolution in terms of molecular properties such as folding, flexibility, and dynamics provides us with another very unique and necessary dimension to examine molecular and submolecular mechanisms作者: 擋泥板 時(shí)間: 2025-4-2 00:12 作者: 演繹 時(shí)間: 2025-4-2 03:10
Cell-Based Assays for Neurotoxins,tions that are currently used, discusses advantages and limitations of differentiation methods, and reviews some initial applications. Finally, developing techniques are presented that are anticipated to increase throughput, sensitivity, and relevance. While the transition to moderate-throughput ass作者: uncertain 時(shí)間: 2025-4-2 07:36 作者: 急急忙忙 時(shí)間: 2025-4-2 13:18
UICC International Union Against Cancerf trace levels of either toxin in biofluid samples is challenged by their short half-life in circulation due to efficient sequestering of these toxins into the target organs. This chapter provides an overview of the latest developments, from the authors’ laboratory as well as from open literature, i作者: nurture 時(shí)間: 2025-4-2 16:47
Natürliche Entwicklung des Krebsesepted diagnostic method for BoNTs is the mouse bioassay, which takes 4 days to complete. This clearly cannot meet the immediate need for clinical diagnosis of botulism, botulinum detection in field conditions, and screening of large scale samples. Consequently, the clinical diagnosis of botulism rel
