標(biāo)題: Titlebook: Biological Small Angle Scattering: Techniques, Strategies and Tips; Barnali Chaudhuri,Inés G. Mu?oz,Volker S. Urban Book 2017 Springer Nat [打印本頁] 作者: Guffaw 時間: 2025-3-21 18:57
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書目名稱Biological Small Angle Scattering: Techniques, Strategies and Tips讀者反饋學(xué)科排名
作者: 缺陷 時間: 2025-3-21 22:34 作者: anarchist 時間: 2025-3-22 02:57 作者: Fortuitous 時間: 2025-3-22 06:22
How to Analyze and Present SAS Data for Publication,gical, functional and even time resolved conditions. However, reconstructing three dimensional structures from SAS data is inherently ambiguous, as no information about orientation and phase is available. In addition experimental artifacts such as radiation damage, concentration effects and incorrec作者: 伙伴 時間: 2025-3-22 12:22 作者: dialect 時間: 2025-3-22 14:44
SAS-Based Structural Modelling and Model Validation,ing inhomogeneities at low resolution. An important example of such systems are solutions of biological macromolecules. Rapid development in the methodology for solution scattering data interpretation and model building during the last two decades brought the analysis far beyond the determination of作者: 確保 時間: 2025-3-22 18:31 作者: 擋泥板 時間: 2025-3-22 21:26
What Can We Learn from Wide-Angle Solution Scattering?,e (SAXS) data. It is possible to accurately predict WAXS scattering on the basis of atomic coordinate sets and thus use it as a means of testing molecular models constructed on the basis of crystallography, molecular dynamics (MD), cryo-electron microscopy or . modeling. WAXS data may provide insigh作者: intercede 時間: 2025-3-23 05:03 作者: guardianship 時間: 2025-3-23 06:55
High Resolution Distance Distributions Determined by X-Ray and Neutron Scattering,heir chemistry, biological macromolecules undergo structural changes over distances ranging from atomic to micrometer scales. X-ray and neutron scattering provide three key assets for tackling this challenge. First, they may be conducted on solutions where the macromolecules are free to sample the c作者: 種子 時間: 2025-3-23 11:32 作者: Mosaic 時間: 2025-3-23 14:29
Applications of SANS to Study Membrane Protein Systems,le in complement to other structural biology techniques such as cryo-EM, NMR and SAXS. In combination with deuteration of components and/or contrast variation (H.O:D.O exchange in the buffer) SANS allows to separate structural information from the protein and the detergent/lipid parts in solution. A作者: CAPE 時間: 2025-3-23 18:32 作者: Pde5-Inhibitors 時間: 2025-3-24 00:37
A Practical Guide to iSPOT Modeling: An Integrative Structural Biology Platform,tructural techniques. Here, we provide a practical protocol for implementing our integrated iSPOT platform by integrating three different biophysical techniques: small-angle X-ray scattering (SAXS), hydroxyl radical footprinting, and computational docking simulations. Specifically, individual techni作者: 催眠 時間: 2025-3-24 03:58
Small Angle Scattering for Pharmaceutical Applications: From Drugs to Drug Delivery Systems,As drug delivery devices become more functionalized and continue decreasing in size, the ability to elucidate details on size scales smaller than those available from optical techniques becomes extremely pertinent. Information gathered from small angle scattering therefore aids the endeavor of optim作者: accordance 時間: 2025-3-24 09:08
Biological Small Angle Scattering: Techniques, Strategies and Tips978-981-10-6038-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: jagged 時間: 2025-3-24 11:29 作者: conscribe 時間: 2025-3-24 15:23
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/b/image/187467.jpg作者: mastoid-bone 時間: 2025-3-24 21:08 作者: ascetic 時間: 2025-3-25 02:55
978-981-13-5555-4Springer Nature Singapore Pte Ltd. 2017作者: AVERT 時間: 2025-3-25 03:29 作者: cartilage 時間: 2025-3-25 07:36
https://doi.org/10.1007/978-3-642-87189-4ough a three-step process of planning, preparing and performing a basic SAXS measurement. The minimal requirements necessary to prepare samples are described specifically for protein and other macromolecular samples in solution. We address the very important aspects in terms of sample characterizati作者: judiciousness 時間: 2025-3-25 12:13
https://doi.org/10.1007/978-3-642-49918-0ing between the sample and background can be achieved using dialysis methods but in biological SAXS of monodisperse systems, sample preparation is routinely being performed with size exclusion chromatography (SEC). SEC is the most reliable method for SAXS sample preparation as the method not only pu作者: 著名 時間: 2025-3-25 16:13 作者: BOOM 時間: 2025-3-25 23:57
https://doi.org/10.1007/978-3-662-36560-1 of a multi-component biological assembly, as well as the spatial arrangements between the components. The large difference in the neutron scattering properties between hydrogen and deuterium is key to the method. Isotopic substitution of deuterium for some or all of the hydrogen in either the molec作者: 北極人 時間: 2025-3-26 02:01
https://doi.org/10.1007/978-3-662-36560-1ing inhomogeneities at low resolution. An important example of such systems are solutions of biological macromolecules. Rapid development in the methodology for solution scattering data interpretation and model building during the last two decades brought the analysis far beyond the determination of作者: 過于平凡 時間: 2025-3-26 08:00
Immunologische Herzerkrankungen,in cell regulation and signalling, and their malfunction is linked to severe pathologies. Understanding the functional role of disorder requires the structural characterization of IDPs and the complexes they form. Small-angle Scattering of X-rays (SAXS) and Neutrons (SANS) have notably contributed t作者: inclusive 時間: 2025-3-26 10:22
https://doi.org/10.1007/978-3-642-16481-1e (SAXS) data. It is possible to accurately predict WAXS scattering on the basis of atomic coordinate sets and thus use it as a means of testing molecular models constructed on the basis of crystallography, molecular dynamics (MD), cryo-electron microscopy or . modeling. WAXS data may provide insigh作者: inspired 時間: 2025-3-26 14:09
Angeborene Herzfehler im Erwachsenenalter,w, the aggregation process starts from an ensemble of native states that convert into transiently formed oligomers, higher order assemblies and protofibrils and, finally, fibrils. The different species exist in equilibrium in solution leading to a high degree of sample heterogeneity. It is impossibl作者: 鄙視讀作 時間: 2025-3-26 17:39
,Akute Herzinsuffizienz und Lungen?dem,heir chemistry, biological macromolecules undergo structural changes over distances ranging from atomic to micrometer scales. X-ray and neutron scattering provide three key assets for tackling this challenge. First, they may be conducted on solutions where the macromolecules are free to sample the c作者: Cervical-Spine 時間: 2025-3-27 00:05 作者: BLAND 時間: 2025-3-27 01:55 作者: 統(tǒng)治人類 時間: 2025-3-27 08:41 作者: 冥想后 時間: 2025-3-27 12:13 作者: Spangle 時間: 2025-3-27 17:07 作者: STAT 時間: 2025-3-27 21:09
0065-2598 surfactant micelles or vesicles. SAS is also used for studying dynamic processes of protein fibrillation in amyloid diseases, and pharmaceutical drug delivery. The combination with size-exclusion chromatograph978-981-13-5555-4978-981-10-6038-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 腐敗 時間: 2025-3-27 23:03 作者: 除草劑 時間: 2025-3-28 04:39 作者: insolence 時間: 2025-3-28 10:17
https://doi.org/10.1007/978-3-662-36560-1nd hybrid modelling approaches, solution scattering is synergistically used with other structural techniques utilizing the complementary information such as atomic models of the components, intramolecular contacts, subunits orientations etc. for the reconstruction of complex systems. The usual requi作者: 注意 時間: 2025-3-28 13:57
https://doi.org/10.1007/978-3-642-16481-1ovide information on the spatial extent of large-scale structural fluctuations that are difficult to obtain by other means. Direct comparison with the results of MD simulations are becoming possible. Because it is particularly sensitive to small changes in structure and flexibility it provides uniqu作者: Ferritin 時間: 2025-3-28 18:40
Angeborene Herzfehler im Erwachsenenalter,ing of the individual components involved during the fibrillation, notably without physical separation of the species. In this chapter we explain how to optimize a small angle scattering analysis of the fibrillation process and the basic principles behind analysis of the data. We include several pra作者: 共同時代 時間: 2025-3-28 20:43 作者: G-spot 時間: 2025-3-29 01:13 作者: MORPH 時間: 2025-3-29 03:34
G. Riecker,B. E. Strauer,B. Lüderitz,W. Hortcomplementary techniques. Second, solution scattering data are frequently applied in situations when a method such NMR or X-ray crystallography cannot provide a satisfactory structural picture, which makes these additional restraints highly desirable. Maturation of the hybrid bio-SAS approaches brin作者: Ablation 時間: 2025-3-29 07:30
Small Angle Scattering: Historical Perspective and Future Outlook, systems that are hard to crystalize, and in particular the development and availability of data analysis software together with the overall access to computational resources powerful enough to run them. Today, SAS is an established and widely used tool for structural studies on bio-macromolecules. 作者: 被詛咒的人 時間: 2025-3-29 11:33
Designing and Performing Biological Solution Small-Angle Neutron Scattering Contrast Variation Expeinciples of SANS theory that are important for contrast variation, essential considerations for experiment design and execution, and the proper approach to data analysis and structure modeling. As sample quality is extremely important for a successful contrast variation experiment, sample issues tha作者: hypertension 時間: 2025-3-29 18:37
SAS-Based Structural Modelling and Model Validation,nd hybrid modelling approaches, solution scattering is synergistically used with other structural techniques utilizing the complementary information such as atomic models of the components, intramolecular contacts, subunits orientations etc. for the reconstruction of complex systems. The usual requi作者: 銼屑 時間: 2025-3-29 20:40 作者: 詳細(xì)目錄 時間: 2025-3-30 01:45 作者: plasma 時間: 2025-3-30 04:49
High Resolution Distance Distributions Determined by X-Ray and Neutron Scattering, the scales and variety of phenomenon interrogated have led to an assortment of functions that describe distances and changes thereof. Here we review scattering studies that characterize biological phenomenon at distances ranging from atomic to 50?nm. We also distinguish the distance distribution fu作者: 榮幸 時間: 2025-3-30 08:15
Applications of SANS to Study Membrane Protein Systems,sing simple, geometric models. The next sections deal with more sophisticated modelling approaches including . shape reconstructions and full-atomic models in the presence of detergent/lipid and specific results obtained by these approaches. After a short comparison with the SAXS technique, this boo作者: accordance 時間: 2025-3-30 15:51
Hybrid Applications of Solution Scattering to Aid Structural Biology,complementary techniques. Second, solution scattering data are frequently applied in situations when a method such NMR or X-ray crystallography cannot provide a satisfactory structural picture, which makes these additional restraints highly desirable. Maturation of the hybrid bio-SAS approaches brin作者: 鄙視讀作 時間: 2025-3-30 18:34
Book 2017or studying multi-component assemblies as well as membrane proteins that are stabilized in surfactant micelles or vesicles. SAS is also used for studying dynamic processes of protein fibrillation in amyloid diseases, and pharmaceutical drug delivery. The combination with size-exclusion chromatograph作者: 喧鬧 時間: 2025-3-30 20:49 作者: Basilar-Artery 時間: 2025-3-31 02:30
https://doi.org/10.1007/978-3-662-08114-3ques are described from experimental and/or computational perspectives, and complementary structural information from these different techniques are integrated for accurate characterization of the structures of large protein-protein complexes.作者: Atrium 時間: 2025-3-31 07:03
