標(biāo)題: Titlebook: Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates; W. E. G. Müller,H. C. Schr?der Book 1994 Sprin [打印本頁] 作者: 關(guān)稅 時間: 2025-3-21 17:20
書目名稱Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates影響因子(影響力)
書目名稱Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates影響因子(影響力)學(xué)科排名
書目名稱Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates網(wǎng)絡(luò)公開度
書目名稱Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates被引頻次
書目名稱Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates被引頻次學(xué)科排名
書目名稱Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates年度引用
書目名稱Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates年度引用學(xué)科排名
書目名稱Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates讀者反饋
書目名稱Biological Response Modifiers — Interferons, Double-Stranded RNA and 2′,5′-Oligoadenylates讀者反饋學(xué)科排名
作者: AWRY 時間: 2025-3-21 22:39
Klinisch angewandte Immunologieosenthal 1988) and the inhibition of glycosylation by prostaglandin A (Santoro et al. 1989) or 2-deoxyglucose (Blough and Ray 1980). However, if the virus is not killed, such a strategy can lead to the development of a drug-resistant virus (Field and Goldthorpe 1989).作者: 使無效 時間: 2025-3-22 02:58
Double-Stranded RNAs as Gene Activators,f dsRNA are achieved through activation of a defined set of genes (O’Malley et al. 1979; Stewart 1979; De Maeyer and De Maeyer-Guignard 1988; Haines et al. 1991). As a consequence, cells synthesize new proteins that change their growth capacity and modulate their functions.作者: FEAS 時間: 2025-3-22 04:41 作者: 多骨 時間: 2025-3-22 10:25 作者: 谷物 時間: 2025-3-22 16:32
,Chemical Synthesis of 2′,5′-0ligoadenylate Analogues,heir antiviral properties (Sehgal et al. 1983), the inhibition of cell growth, the inhibition of tumor cell proliferation, their augmentation of natural killer (NK) activity, the modulation of immune response, the interaction of nuclear formation and the delay of cells entering into S-phase of the cell cycle (Suhadolnik et al. 1983).作者: 浮雕 時間: 2025-3-22 17:44
,2′,5′-0ligoadenylate Synthetase in Autoimmune BB Rats,n the destructive process, but the triggering event still remains elusive. In the many attempts to understand the etiopathogenesis of IDDM great help has come from different animal models like the streptozotocin-treated mice, the NOD (nonobese diabetic) mice, and the spontaneously diabetic BB rat.作者: 的染料 時間: 2025-3-23 00:59
0079-6484 also help to develop further a solid scientific rationale for the practical use of heterologous immunomodulators in the clinics.978-3-642-78551-1978-3-642-78549-8Series ISSN 0079-6484 Series E-ISSN 2197-8484 作者: Gleason-score 時間: 2025-3-23 03:22 作者: 江湖騙子 時間: 2025-3-23 06:12 作者: 使人入神 時間: 2025-3-23 13:12 作者: 較早 時間: 2025-3-23 15:02 作者: 蹣跚 時間: 2025-3-23 20:28 作者: gain631 時間: 2025-3-24 00:45 作者: 載貨清單 時間: 2025-3-24 05:25
D. H?lzel,G. Schubert-Fritschle,Ch. Thiemeons. A restriction of available bioactive dsRNA (or of dsRNA-dependent enzymes) may play an important role in the disease progression. The results summarized in this review show that defects in dsRNA-dependent pathways exhibited by AIDS patients can be reversed, at least in part, by exogenously supplied dsRNA.作者: Affection 時間: 2025-3-24 08:40
https://doi.org/10.1007/978-3-7091-9188-0e, 2- and 8-azido analogs of 2-5A to RNase L, and azido dsRNAs to 2-5A synthetase and p68 kinase is described. In addition, the newly discovered role of the 2-5A molecule as an inhibitor of HIV-l reverse transcriptase (RT) is discussed.作者: uncertain 時間: 2025-3-24 14:37
Activation of the dsRNA-Dependent Kinase,to a functional enzyme, and in some cases prevention of its activation, is dependent on RNAs containing accessible double-stranded structures. However, like several other protein kinases, once activated, it elicits a modulating effect that alters cellular processes.作者: avulsion 時間: 2025-3-24 15:31 作者: 先行 時間: 2025-3-24 20:09
Photolabeling of the Enzymes of the 2-5A Synthetase/RNase L/p68 Kinase Antiviral Systems with Azidoe, 2- and 8-azido analogs of 2-5A to RNase L, and azido dsRNAs to 2-5A synthetase and p68 kinase is described. In addition, the newly discovered role of the 2-5A molecule as an inhibitor of HIV-l reverse transcriptase (RT) is discussed.作者: 口味 時間: 2025-3-24 23:28 作者: 山頂可休息 時間: 2025-3-25 04:52
https://doi.org/10.1007/978-3-642-78549-8Doppelstrang-RNA; HIV; Immunantwort; RNA; Virusinfektion; Zytokine; cancer; cancer therapy; cytokine; cytokin作者: Delectable 時間: 2025-3-25 08:56
978-3-642-78551-1Springer-Verlag Berlin Heidelberg 1994作者: 金絲雀 時間: 2025-3-25 15:19
2-5A and Virus Infection,ately, cells and living organisms are provided with various defense mechanisms against viral infection. The most important of these is interferon (IFN), which performs a multitude of functions, particularly in the regulation of cell growth, cell differentiation and immune responses (Gastl and Huber 1988).作者: 粗語 時間: 2025-3-25 16:25 作者: 創(chuàng)作 時間: 2025-3-25 23:05 作者: indoctrinate 時間: 2025-3-26 01:26 作者: 敘述 時間: 2025-3-26 08:11
Zusammenfassende Diskussion und Ausblick,ulation of host factors during initial host-pathogen interactions is initiated by host recognition of viral signals, and disease development is conditioned by the subsequent response to these signals. The identity and function of host proteins involved in the recognition and response to pathogen sig作者: Strength 時間: 2025-3-26 11:09
D. H?lzel,G. Schubert-Fritschle,Ch. Thiemes, see Petska et al. 1987; Sen and Lengyel 1992). In this review, we will discuss the regulation of the double-stranded (ds) RNA-activated protein kinase which is one of more than 30 proteins induced by interferon. The dsRNA-activated protein kinase will be referred to as the P68 kinase (Katze et al作者: parsimony 時間: 2025-3-26 14:57
D. H?lzel,G. Schubert-Fritschle,Ch. Thiemeosynthesis of interferon (IFN), production of 2′,5′-oligoadenylate (2-5A), ribonuclease L (RNase L) activity and different cell-mediated immune functions. A restriction of available bioactive dsRNA (or of dsRNA-dependent enzymes) may play an important role in the disease progression. The results sum作者: Militia 時間: 2025-3-26 18:30
Klinisch angewandte Immunologieogenic, and specific for viral functions. Effective viral chemotherapy has been hindered because viruses employ host cell systems to replicate. Recent advances in molecular virology provide a rational basis for the development of antiviral compounds that will interfere with biochemically defined, vi作者: idiopathic 時間: 2025-3-26 22:37 作者: Accolade 時間: 2025-3-27 02:59 作者: Inclement 時間: 2025-3-27 06:51
https://doi.org/10.1007/978-3-211-99468-9ately, cells and living organisms are provided with various defense mechanisms against viral infection. The most important of these is interferon (IFN), which performs a multitude of functions, particularly in the regulation of cell growth, cell differentiation and immune responses (Gastl and Huber 作者: LAPSE 時間: 2025-3-27 11:51 作者: 形容詞 時間: 2025-3-27 16:16
Klinisch-mikrobiologisches Managemento-thetopoulos et al. 1984; Marliss et al. 1982). This syndrome is believed to be a cell-mediated autoimmune process that selectively destroys the insulin producing .-cells in the islets of Langerhans in the pancreas. Throughout the years many ingenious hypotheses have been created in order to explai作者: cipher 時間: 2025-3-27 21:07
Erregerbedingte Darmerkrankungen,ent when an involvement of both low molecular weight intracellular regulators in the control of cell proliferation was demonstrated: the action of both cAMP and 2–5A on cell growth processes suggested a coordination of their activity and a regulation of each of these agents by the other.作者: 面包屑 時間: 2025-3-27 23:50 作者: 男生如果明白 時間: 2025-3-28 04:49 作者: Sleep-Paralysis 時間: 2025-3-28 08:03 作者: Keshan-disease 時間: 2025-3-28 12:24 作者: 慢慢沖刷 時間: 2025-3-28 17:13 作者: 變異 時間: 2025-3-28 22:12 作者: 治愈 時間: 2025-3-29 01:06
Progress in Molecular and Subcellular Biologyhttp://image.papertrans.cn/b/image/187453.jpg作者: 正常 時間: 2025-3-29 06:34
Activation of the dsRNA-Dependent Kinase,tein kinase, is an interferon-induced serine/threonine protein kinase. It is uniquely distinguished from other protein kinases in that its activation to a functional enzyme, and in some cases prevention of its activation, is dependent on RNAs containing accessible double-stranded structures. However作者: hauteur 時間: 2025-3-29 10:21
Double-Stranded RNAs as Gene Activators,d that dsRNA is the active agent in an extract of a . preparation which, following injection into rabbits, induces interferon (IFN) in serum. They also showed that various natural (i.e. reovirus genomic RNA) or synthetic (i.e. poly rI:rC) dsRNAs induce IFN-α/β in animals and cultured animal cells (F作者: 策略 時間: 2025-3-29 14:51 作者: NEX 時間: 2025-3-29 15:40 作者: Bridle 時間: 2025-3-29 23:23
Mechanism of the Antiretroviral Effect of dsRNA,osynthesis of interferon (IFN), production of 2′,5′-oligoadenylate (2-5A), ribonuclease L (RNase L) activity and different cell-mediated immune functions. A restriction of available bioactive dsRNA (or of dsRNA-dependent enzymes) may play an important role in the disease progression. The results sum作者: affect 時間: 2025-3-30 01:24
The Antiviral Activity of RNA-Dye Combinations,ogenic, and specific for viral functions. Effective viral chemotherapy has been hindered because viruses employ host cell systems to replicate. Recent advances in molecular virology provide a rational basis for the development of antiviral compounds that will interfere with biochemically defined, vi作者: ABIDE 時間: 2025-3-30 04:48 作者: 借喻 時間: 2025-3-30 09:46 作者: 消散 時間: 2025-3-30 16:09
2-5A and Virus Infection,ately, cells and living organisms are provided with various defense mechanisms against viral infection. The most important of these is interferon (IFN), which performs a multitude of functions, particularly in the regulation of cell growth, cell differentiation and immune responses (Gastl and Huber 作者: Thymus 時間: 2025-3-30 18:51
The 2-5A System and HIV Infection,al disease is associated with various clinical manifestations, including the acquisition of an immunodeficient state, the frequent presence of neurological disorders, and some malignancies (reviewed in Barré-Sinoussi et al. 1983; Wong-Staal and Gallo 1985; Fauci 1988). Immunologic dysfunctions cause作者: 牌帶來 時間: 2025-3-30 23:48 作者: ovation 時間: 2025-3-31 03:15
