作者: 鄙視讀作 時(shí)間: 2025-3-21 23:44 作者: 船員 時(shí)間: 2025-3-22 02:27 作者: 大氣層 時(shí)間: 2025-3-22 05:35
Bacterial Cytochrome P-450 Monooxygenasesvement in many different types of biological functions. In the endoplasmic reticulum of hepatic cells, P450 cytochromes participate in the detoxification of xenobiotic compounds, such as the hydroxylation of the pharmaceutical sedative phenobarbital. Other liver microsomal P450 systems will catalyze作者: vascular 時(shí)間: 2025-3-22 09:48 作者: 可用 時(shí)間: 2025-3-22 13:35 作者: 極小量 時(shí)間: 2025-3-22 19:10
https://doi.org/10.1007/978-3-658-27884-7uction reactions, where one substrate is oxidized and a second is reduced. For all these enzymes, each catalytic cycle consists of two distinct processes, the acceptance of redox equivalents from a reducing substrate and the transfer of these equivalents to an oxidized acceptor. Accordingly, catalys作者: Expiration 時(shí)間: 2025-3-22 23:09
Statistisch-klimatologische Methodik,vement in many different types of biological functions. In the endoplasmic reticulum of hepatic cells, P450 cytochromes participate in the detoxification of xenobiotic compounds, such as the hydroxylation of the pharmaceutical sedative phenobarbital. Other liver microsomal P450 systems will catalyze作者: oxidize 時(shí)間: 2025-3-23 03:54 作者: 龍蝦 時(shí)間: 2025-3-23 06:00 作者: chance 時(shí)間: 2025-3-23 11:26
Klimatologische Informationsquellen, the cyclo-oxygenase enzyme, which biosynthesises the prostaglandin endoperoxides is a fascinating and unique dioxygenase and there can be few other enzymes in the body, which are capable of producing such a wide range of biologically active substances.作者: Synthesize 時(shí)間: 2025-3-23 16:38 作者: fertilizer 時(shí)間: 2025-3-23 19:19
Lipoxygenases from Plant and Animal Originperoxides. For example, the products of the enzymic dioxygenation of linoleic acid are 13-S(L)-hydroperoxy-9-.,11-.- (13-S-HPOD), 9-R(L)-hydroperoxy-10-.,12-.- (9-R-HPOD) or 9-S(D)-hydroperoxy-10-.,12-.-octadecadienoic acid (9-S-HPOD) (Scheme 1).作者: anarchist 時(shí)間: 2025-3-24 00:17
Physiological Reactions of Arachidonic Acid Oxygenation Products the cyclo-oxygenase enzyme, which biosynthesises the prostaglandin endoperoxides is a fascinating and unique dioxygenase and there can be few other enzymes in the body, which are capable of producing such a wide range of biologically active substances.作者: minaret 時(shí)間: 2025-3-24 03:05
Vorbehalte gegenüber Klimaschutzproblemenscovered (Mason et al. 1955; Hayaishi et al. 1955) and the number and variety of known biological dioxygen activation reactions greatly increased. The chemical biology of dioxygen is now very diverse and involves intercession of many dioxygen binding and activating proteins (Keevil and Mason 1978; Mason 1981).作者: Torrid 時(shí)間: 2025-3-24 06:35
https://doi.org/10.37307/b.978-3-503-20687-23; Stenkamp and Jensen 1979; Stenkamp et al. 1981), and hemocyanins (Mangum 1980; Markl et al. 1982; van Holden and Miller 1982; Preaux and Gielens 1983), which utilize dinuclear iron and copper centers, respectively, for this purpose (see Table 1).作者: 獨(dú)行者 時(shí)間: 2025-3-24 12:48 作者: 自負(fù)的人 時(shí)間: 2025-3-24 16:42 作者: LEVY 時(shí)間: 2025-3-24 22:29
Reversible Dioxygen Binding3; Stenkamp and Jensen 1979; Stenkamp et al. 1981), and hemocyanins (Mangum 1980; Markl et al. 1982; van Holden and Miller 1982; Preaux and Gielens 1983), which utilize dinuclear iron and copper centers, respectively, for this purpose (see Table 1).作者: exceptional 時(shí)間: 2025-3-25 02:46
Reactive Intermediates Derived from Cytochrome P-450 Monooxygenases). These cytochromes P-450 play a key role not only in pharmacology since they control the elimination rate of drugs, but also in toxicology since they seem to be the privileged sites of formation of reactive intermediates inside the cell.作者: Bother 時(shí)間: 2025-3-25 04:19 作者: Muscularis 時(shí)間: 2025-3-25 08:46 作者: eustachian-tube 時(shí)間: 2025-3-25 11:56
Otto Warburg:A Personal Recollectionto this, he studied the roots of Warburg’s personality and investigated the sources of the publications. After this biography, which in its affectionate sincerity honors both the biographer and his subject, what can be the further purpose and sense of my contribution?作者: 閑蕩 時(shí)間: 2025-3-25 16:37
Cytochrome , Oxidase and Related Enzymesknow that the views of these two pioneer investigators were, in fact, both correct: the functional unit of cytochrome oxidase contains two heme A prosthetic groups and two ions of copper (Malmstr?m 1982).作者: 萬靈丹 時(shí)間: 2025-3-25 22:53
https://doi.org/10.1007/978-3-642-69467-7Activation; Atmungskette; Oxidation; Warburg, Otto; biochemistry; enzymes; regulation作者: 補(bǔ)充 時(shí)間: 2025-3-26 03:27 作者: STENT 時(shí)間: 2025-3-26 06:33
https://doi.org/10.1007/978-3-658-39354-0], it was also published in German [2]. The first written communication by Krebs from Warburg’s laboratory dates from 1927 [3]. In the 43 years preceding Warburg’s death, there existed a bond between the two men profiting in its personal as well as in its professional aspect from the stimulating ten作者: BOGUS 時(shí)間: 2025-3-26 11:43
Jens Rüdiger,Franziska R?hrig,Teresa Stuckes, extensive results are also available for complexes of these enzymes with substrates, inhibitors, coenzymes, and coenzyme analogs. I shall review here the wealth of information obtained from these studies and show the stimulus derived in some quite unexpected topics.作者: 集中營 時(shí)間: 2025-3-26 13:40 作者: wreathe 時(shí)間: 2025-3-26 17:13
Schriften zu Tourismus und Freizeittein and to the (kinetic) mechanism by which the covaient polypeptide chain achieves its three-dimensional structure (Jaenicke 1980). In this article, we refer to the second alternative which may be considered the postlude of translation. The experimental approach makes use of the reversibility of p作者: 專橫 時(shí)間: 2025-3-27 00:14 作者: 礦石 時(shí)間: 2025-3-27 02:07 作者: 值得尊敬 時(shí)間: 2025-3-27 06:08 作者: 誹謗 時(shí)間: 2025-3-27 10:36
Vorbehalte gegenüber Klimaschutzproblemensince he and Negelein established cytochrome a. as the “oxygen transporting” or autoxidizable component of the respiratory chain (Warburg and Negelein 1928), laying foundations for the modern structure of bioenergetics (Keilin 1966). Twenty-five years later, a new mode of dioxygen utilization was di作者: Conscientious 時(shí)間: 2025-3-27 15:19
https://doi.org/10.37307/b.978-3-503-20687-2tenberg et al. 1974) reversible dioxygen-metal adducts have to be formed (Antonini and Brunori 1971). Three classes of such adducts exist:Hemoglobins and myoglobins which provide mononuclear iron centers for binding of dioxygen (Antonini and Brunori 1971; Christomanos 1973), hemerythrins (Llinas 197作者: conference 時(shí)間: 2025-3-27 18:40 作者: Nausea 時(shí)間: 2025-3-27 23:43 作者: 肉身 時(shí)間: 2025-3-28 04:54
Klimatologische Informationsquellen,ntific interests, he never worked directly in the field of prostaglandin biosynthesis or action. As the previous speaker Vliegenthart has pointed out, the cyclo-oxygenase enzyme, which biosynthesises the prostaglandin endoperoxides is a fascinating and unique dioxygenase and there can be few other e作者: 大酒杯 時(shí)間: 2025-3-28 06:31
Statistisch-klimatologische Methodik,uce unique spectroscopic properties (1). Together with associated redox components, the P450 heme proteins function as monooxygenases, catalyzing the two-electron reduction of dioxygen to form a molecule of water and an activated oxygen atom (2). The subsequent transfer of this oxygen atom to hydroc作者: 避開 時(shí)間: 2025-3-28 13:49
https://doi.org/10.1007/978-3-663-02626-6in several organs and tissues with a maximum concentration in the liver. Some of them are in charge of the elimination of foreign compounds (xenobiotics) from the body and have to hydroxylate a broad spectrum of lipophilic compounds making them more hydrophilic and more easily excreted (Ullrich 1979作者: 易怒 時(shí)間: 2025-3-28 18:13 作者: 上流社會 時(shí)間: 2025-3-28 21:03
Binding of Coenzyme Analogs to NAD-Dependent Dehydrogenaseseceived great impetus from the structural analysis of this enzyme by the cristallographic group of Br?ndén (Uppsala). The collaboration of both groups has led us to draw a number of conclusions of general interest to biochemistry.作者: 伸展 時(shí)間: 2025-3-29 02:33
Biological Oxidations978-3-642-69467-7Series ISSN 0366-5887 作者: 帶子 時(shí)間: 2025-3-29 06:36
0366-5887 Overview: 978-3-642-69469-1978-3-642-69467-7Series ISSN 0366-5887 作者: 冰雹 時(shí)間: 2025-3-29 09:03 作者: Neuropeptides 時(shí)間: 2025-3-29 15:21
https://doi.org/10.37307/b.978-3-503-23769-2eceived great impetus from the structural analysis of this enzyme by the cristallographic group of Br?ndén (Uppsala). The collaboration of both groups has led us to draw a number of conclusions of general interest to biochemistry.作者: 作嘔 時(shí)間: 2025-3-29 15:51 作者: Pelvic-Floor 時(shí)間: 2025-3-29 23:44
Otto Warburg:A Personal Recollection], it was also published in German [2]. The first written communication by Krebs from Warburg’s laboratory dates from 1927 [3]. In the 43 years preceding Warburg’s death, there existed a bond between the two men profiting in its personal as well as in its professional aspect from the stimulating ten作者: 詳細(xì)目錄 時(shí)間: 2025-3-30 00:23 作者: Intuitive 時(shí)間: 2025-3-30 06:38
Binding of Coenzyme Analogs to NAD-Dependent Dehydrogenaseseceived great impetus from the structural analysis of this enzyme by the cristallographic group of Br?ndén (Uppsala). The collaboration of both groups has led us to draw a number of conclusions of general interest to biochemistry.作者: Exhilarate 時(shí)間: 2025-3-30 08:40 作者: 改變 時(shí)間: 2025-3-30 13:59
Flavoproteins of Known Three-Dimensional Structureno acid oxidase, respectively. More than 100 flavoenzymes have been described in the meantime (Dixon and Webb 1979); for four of them, structural data are known. These are glycolate oxidase (Lind quist and Br?nden 1980), an FMN-dependent enzyme which probably has a chain fold in common with triose p作者: Abjure 時(shí)間: 2025-3-30 18:36
The Mechanism of Action of Flavoprotein - Catalyzed Reactionsvin chromophore by Kuhn and Wagner-Jauregg (1930) and the 50th anniversary of the isolation of the first flavoprotein, the Old Yellow Enzyme of brewers bottom yeast (Warburg and Christian 1933). In the intervening 50 years, some 200 different flavoproteins have been recognized, making this one of th作者: 潛伏期 時(shí)間: 2025-3-31 00:03
Mechanistic Studies on Mercuric Ion Reductase and Cyclohexanone Oxygenase:Pharmacologic and Toxicoloars ago, a vast amount of biochemical and chemical information has accumulated on the redox roles of flavins in biological systems. Flavoenzymes are unmatched in their redox versatility and in the diversity of substrate structural types oxidized and reduced, reflecting the finely balanced chemical p
