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標(biāo)題: Titlebook: Biocombinatorial Approaches for Drug Finding; W. Wohlleben,T. Spellig,B. Müller-Tiemann Conference proceedings 2005 Springer-Verlag Berlin [打印本頁]

作者: Ejaculation    時間: 2025-3-21 16:37
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作者: 現(xiàn)任者    時間: 2025-3-21 23:57
https://doi.org/10.1007/978-3-322-81397-8e chemistry, genetics and molecular biology are indispensable. The NRPSs can provide such interesting tools to generate and modify novel products. The recently gained structural and mechanistic information on NRPSs have made this class of multienzymes a powerful native tool box that would help to ac
作者: Ankylo-    時間: 2025-3-22 03:42
Krankenkassen — Zwang oder Segen? these GTs show a remarkable flexibility towards the donor and the acceptor molecules making them most valuable for combinatorial biosynthesis. Future work is expected to focus on learning more about sugar biosynthesis, sugar modification and sugar attachment to support in vivo engineering of novel
作者: Acclaim    時間: 2025-3-22 07:57

作者: flourish    時間: 2025-3-22 08:54

作者: indoctrinate    時間: 2025-3-22 15:19
https://doi.org/10.1007/b138552Combinatorial Biosynthesis; Diversity; Nonribosomal peptides; Polyketides; Proteome; drug; drug discovery;
作者: adulterant    時間: 2025-3-22 18:16
978-3-642-42189-1Springer-Verlag Berlin Heidelberg 2005
作者: hypotension    時間: 2025-3-23 01:17
Biocombinatorial Approaches for Drug Finding978-3-540-27055-3Series ISSN 0947-6075
作者: incisive    時間: 2025-3-23 04:41

作者: 陶器    時間: 2025-3-23 08:39

作者: 使顯得不重要    時間: 2025-3-23 13:10
Einzelne ?u?erungen in den Frageb?gene critical for productive engineering efforts. Although mechanistic and specificity studies have shown that natural PKS domains are generally not best-suited to serve as universal combinatorial units, recent insights such as those afforded by the mycolactone PKS should allow progress towards this goal.
作者: 暗諷    時間: 2025-3-23 15:40

作者: LIKEN    時間: 2025-3-23 20:30

作者: 推延    時間: 2025-3-23 23:18

作者: Apogee    時間: 2025-3-24 02:42

作者: prostatitis    時間: 2025-3-24 08:26

作者: 全面    時間: 2025-3-24 14:04

作者: Pseudoephedrine    時間: 2025-3-24 17:58

作者: 現(xiàn)實    時間: 2025-3-24 19:14
Sources of Polyketides and Non-Ribosomal Peptides,
作者: 假裝是你    時間: 2025-3-25 01:40

作者: 嚴(yán)峻考驗    時間: 2025-3-25 03:38
Engineering Glycosylation in Bioactive Compounds by Combinatorial Biosynthesis,
作者: 易受騙    時間: 2025-3-25 08:43

作者: 機構(gòu)    時間: 2025-3-25 11:46
From Glucose to Antibiotics: What Controls the Fluxes?,
作者: FEAT    時間: 2025-3-25 18:34
Precursor-Directed Biosynthesis for the Generation of Novel Glycopetides,
作者: duplicate    時間: 2025-3-25 22:59

作者: 玉米棒子    時間: 2025-3-26 02:00
Natural Product Biosynthetic Assembly Lines: Prospects and Challenges for Reprogramming,
作者: ordain    時間: 2025-3-26 04:41
Polyketide Synthases: Mechanisms and Models,ketide medicines. We are beginning to understand those features of subunit organization and structure and their linking and docking elements, which are critical for productive engineering efforts. Although mechanistic and specificity studies have shown that natural PKS domains are generally not best
作者: GENUS    時間: 2025-3-26 12:22
Functional and Structural Basis for Targeted Modification of Non-Ribosomal Peptlde Synthetases,e chemistry, genetics and molecular biology are indispensable. The NRPSs can provide such interesting tools to generate and modify novel products. The recently gained structural and mechanistic information on NRPSs have made this class of multienzymes a powerful native tool box that would help to ac
作者: promote    時間: 2025-3-26 13:05
Glycosyltransferases and Other Tailoring Enzymes as Tools for the Generation of Novel Compounds, these GTs show a remarkable flexibility towards the donor and the acceptor molecules making them most valuable for combinatorial biosynthesis. Future work is expected to focus on learning more about sugar biosynthesis, sugar modification and sugar attachment to support in vivo engineering of novel
作者: 我不怕犧牲    時間: 2025-3-26 18:07
Installing into an Existing Treet decade Artificial Intelligence (AI) has seen a rapid growth in adoption across a range of industry verticals such as automotive, telecommunications, aerospace, and health care. It has been acknowledged that while adoption of AI in the travel industry has been slow, the potential incremental value
作者: 裂縫    時間: 2025-3-26 21:48
As Yeats was Going Down Grafton Street,and causing spoilage. Many cultures all over the world have been preserving fish for centuries using this age-old technique, particularly in areas without easy access to refrigeration. Because of its prolonged shelf life and concentrated flavours, dry fish is highly valued and is an essential food s
作者: inundate    時間: 2025-3-27 01:49
chst eine n?here Erl?uterung. In der neueren geldtheoretischen Diskussion . wird der Begriff der Liquidit?t vorwiegend im Sinne der Liquidit?tstheorie als die tats?chliche oder angenommene Verfügungsmacht über Zahlungsmittel verstanden. Die Liquidit?t beschreibt gleichsam den Rahmen, innerhalb desse
作者: Essential    時間: 2025-3-27 08:29

作者: coalition    時間: 2025-3-27 10:52
Yoshiko Arima Aerzte Dr. Wallbaum, Dr. Danzmann und Dr. Brehmer. Schon früher, in den Jahren 1793 und 1794, hatte ein Travemünder Einwohner Lohmann Projekte zur Errichtung eines Seebades entworfen, die aber aus Mangel an Mitteln nicht zur Ausführung gekommen waren. Die Lübecker konnten sich um die Wende des Jahr
作者: BINGE    時間: 2025-3-27 13:37
Giorgio Monti,Floriana Petronefeld and Günter T?rner, that will be of great interest to maEfforts to improve mathematics education have led educators and researchers to not only study the nature of proficiency, beliefs, and practices in mathematics learn?ing and teaching, but also identify and assess possible influences on stude
作者: 發(fā)生    時間: 2025-3-27 18:13
und Weise kombiniert wird. Ein grundlegender und viel versprechender Ansatz, Wissen aus verschiedenen Gebieten zusammen zu führen, um kreative Probleme zu l?sen, ist die Nutzung von Analogien. Hierbei findet ein Wissenstransfer von einem Objekt oder einer Situation (= Quelle der Analogie) zu einem a
作者: 混合物    時間: 2025-3-27 23:19
j.‘‘ met die woorden sloot Rene Tabak zijn TEDxRadboudUtalk in een muisstil en tot de nok toe gevuld auditorium in Nijmegen af. De pati?nt staat niet alleen centraal, hij is lid van het totale behandelteam, met een actieve rol. Mooie woorden, maar wat zegt dit nu eigenlijk? En vooral, wat betekent d
作者: cochlea    時間: 2025-3-28 03:11
Coherence in Synergeticsatural way to the definition of correlation functions. In chapter 3 I shall remind the reader of some basic properties of the laser and why it is such an interesting subject to study, also with respect to other disciplines. In chapter 4 I shall then explain what synergetics means and shall give an o
作者: 敵手    時間: 2025-3-28 07:24

作者: triptans    時間: 2025-3-28 12:42

作者: 牙齒    時間: 2025-3-28 15:21

作者: deface    時間: 2025-3-28 20:08
Book 2010arketplace. The advantages of using cloud computing include cost savings, speed to market, access to greater computing resources, high availability, and scalability.?.Handbook of Cloud Computing. includes contributions from world experts in the field of cloud computing from academia, research labora
作者: 沒有準(zhǔn)備    時間: 2025-3-28 23:20
Sustained Enablement of AI Ethics in Industrycritical field of study, focusing on the trustworthy development, deployment, and use of AI technologies. In this paper, we explore an AI Ethics concept with a particular focus on sustained enabling factors to guide organizations in navigating the ethical challenges associated with AI adoption.
作者: 農(nóng)學(xué)    時間: 2025-3-29 05:36
The Big Three: Class, Gender, Race, method design on conversation rather than artifact production . It is suggested that such a conversational framework based on Toulmin and Pask may provide a means to establish and test theory building views of enterprise architecture.
作者: 含糊    時間: 2025-3-29 10:42

作者: 執(zhí)    時間: 2025-3-29 14:42
Alessandro Lavacchi,Hamish Miller,Francesco Vizzaounds and scars of being part of multiple systems of oppression and power. Ultimately, Scars makes visible the psychological trauma and scarring that legacies of colonialism have caused to both the descendants of the colonized and the colonizer … and the potential for healing and reconciliation for
作者: Decline    時間: 2025-3-29 17:17

作者: 怪物    時間: 2025-3-29 20:18
Conference proceedings 2022heavily on those least able to bear them. It examines governments subsidies, which supported people and firms through wage subsidies, unemployment benefits, and other fiscal measures, and discusses the question of whether more investment in health care, education, and other public services will stil
作者: 粗魯?shù)娜?nbsp;   時間: 2025-3-30 00:43

作者: helper-T-cells    時間: 2025-3-30 04:13
Randolph Nelsonchnological problems for composite (composable) systems on t.Composite decisions consist of subdecisions and correspond to a composite system.?This approach extends the traditional paradigm of decision making of Herbert A. Simon, i.e. choice of the best alternative(s), and realizes a two-stage solvi
作者: 制度    時間: 2025-3-30 10:58





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