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標(biāo)題: Titlebook: Biochemical Approaches for Glutamatergic Neurotransmission; Sandrine Parrot,Luc Denoroy Book 2018 Springer Science+Business Media LLC 2018 [打印本頁(yè)]

作者: ARGOT    時(shí)間: 2025-3-21 19:34
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作者: 襲擊    時(shí)間: 2025-3-21 22:55

作者: 全面    時(shí)間: 2025-3-22 00:24
Positron Emission Tomography of Metabotropic Glutamate Receptors,linical research besides its well established use in routine clinical practice. PET is a highly multidisciplinary technique requiring specialized knowledge and skills from teams of Chemists, Physicists, and Biologists/Medical staff. In this chapter, we discuss PET methodology through explanation of
作者: Foreknowledge    時(shí)間: 2025-3-22 07:23

作者: 逢迎白雪    時(shí)間: 2025-3-22 10:27

作者: Constrain    時(shí)間: 2025-3-22 13:50

作者: Cholagogue    時(shí)間: 2025-3-22 17:29

作者: 大范圍流行    時(shí)間: 2025-3-22 21:17
Drugs to Tune Up Glutamatergic Systems: Modulators of Glutamate Metabotropic Receptors,ntral nervous system (CNS) disorders. Dysfunction or dysregulation of the glutamatergic system, the main excitatory neurotransmitter system in the CNS, is thought to be associated with multiple CNS disorders including schizophrenia, depression, anxiety, Fragile X syndrome, Parkinson’s disease, and r
作者: entrance    時(shí)間: 2025-3-23 03:52

作者: 狼群    時(shí)間: 2025-3-23 08:03

作者: HEW    時(shí)間: 2025-3-23 10:11

作者: 暫時(shí)別動(dòng)    時(shí)間: 2025-3-23 15:23

作者: ascend    時(shí)間: 2025-3-23 18:04
In Vivo Determination of Glutamate Uptake by Brain Microdialysis,hich induce neuronal dysfunctions and neurological diseases. An evaluation of in vivo glutamate transport can enable to verify the functional impact of alterations previously found in in vitro and ex vivo preparations. The use of brain microdialysis to sample the extracellular medium has allowed to
作者: liaison    時(shí)間: 2025-3-23 23:58

作者: neoplasm    時(shí)間: 2025-3-24 05:42
The Glutamatergic System as Potential Clinical Biomarkers for Blood and Cerebrospinal Fluid Monitortion, and signaling via glutamate receptors. Glutamate is synthesized from glutamine by glutaminase, while it is metabolized to the inhibitory amino acid γ-aminobutyric acid (GABA) by glutamic decarboxylase. Thus, the glutamine-glutamate-GABA cycle plays an important role in both excitatory and inhi
作者: 孵卵器    時(shí)間: 2025-3-24 10:29
Clinical CNS Microdialysis of Glutamate with a Special Methodological Focus on Human Spinal Cord,inical studies, the monitoring of glutamate has revealed tight links between the variations of its interstitial concentration and those of other metabolic biomarkers and partial pressure in oxygen within tissue. The use of microdialysis has allowed to monitor glutamate over several days in patients
作者: 滔滔不絕地講    時(shí)間: 2025-3-24 12:24
Biochemical Approaches for Glutamatergic Neurotransmission978-1-4939-7228-9Series ISSN 0893-2336 Series E-ISSN 1940-6045
作者: 慷慨援助    時(shí)間: 2025-3-24 17:11

作者: MENT    時(shí)間: 2025-3-24 20:37
978-1-4939-8423-7Springer Science+Business Media LLC 2018
作者: 騷動(dòng)    時(shí)間: 2025-3-24 23:51

作者: Common-Migraine    時(shí)間: 2025-3-25 04:00

作者: 暫時(shí)別動(dòng)    時(shí)間: 2025-3-25 10:44
?Das Verschwinden der Glühwürmchen“tamate transporters (vGluTs). Three isoforms of vGluTs have been cloned (vGluT1, vGluT2, and vGluT3), and shown by biochemical studies to selectively transport glutamate. The cloning of vGluTs has facilitated the anatomical and functional analysis of glutamatergic neurons, and while there are commer
作者: HPA533    時(shí)間: 2025-3-25 15:15

作者: CANT    時(shí)間: 2025-3-25 16:53

作者: Lymphocyte    時(shí)間: 2025-3-25 21:33
https://doi.org/10.1007/978-3-322-85774-3 and nitrogen metabolism. The dual roles of glutamate as a neurotransmitter and metabolite are intricately connected. Its unusually high concentration and rapid turnover in brain make it accessible to both proton and .C NMR spectroscopy methods. This has enabled researchers to study the various func
作者: cajole    時(shí)間: 2025-3-26 01:13

作者: disciplined    時(shí)間: 2025-3-26 05:14
Zusammenfassung und Konsequenzen ATP and .-serine. Various release mechanisms have been proposed depending on pathophysiological conditions. Among them, inverted transport, ion channels mediated release, and vesicular release. To better understand how cellular interactions alter glutamate release, we used live imaging techniques t
作者: Feature    時(shí)間: 2025-3-26 09:33

作者: ETHER    時(shí)間: 2025-3-26 14:29
Journalismus als soziales Systemntral nervous system (CNS) disorders. Dysfunction or dysregulation of the glutamatergic system, the main excitatory neurotransmitter system in the CNS, is thought to be associated with multiple CNS disorders including schizophrenia, depression, anxiety, Fragile X syndrome, Parkinson’s disease, and r
作者: DEMN    時(shí)間: 2025-3-26 20:33
Bürgerfunk als Vielfaltsreservent many of the neurophysiological advances that have been made using invertebrate model organisms, from receptor pharmacology to synaptic plasticity and glutamate recycling. We then direct your attention to the crayfish and fruit fly larva neuromuscular junctions, glutamatergic synapses that have be
作者: 恫嚇    時(shí)間: 2025-3-26 23:13

作者: BALK    時(shí)間: 2025-3-27 05:04
Bürgerfunk als Vielfaltsreserveto long-term neuronal damage seen in many neurological disorders, including traumatic brain injury (TBI) and stroke. Therefore, methods for continuous monitoring of extracellular Glu concentrations in the brain can be very useful to clinicians for determining the best timing for pharmacological inte
作者: lipids    時(shí)間: 2025-3-27 05:22
https://doi.org/10.1007/978-3-658-02417-8 microdialysis coupled to a separation micro-method, such an approach offering high chemical selectivity combined to good anatomical and temporal resolution. Among the two separation micro-methods used to determine glutamate in brain microdialysates, namely liquid chromatography and capillary electr
作者: 暫時(shí)別動(dòng)    時(shí)間: 2025-3-27 12:29
https://doi.org/10.1007/978-3-658-02417-8hich induce neuronal dysfunctions and neurological diseases. An evaluation of in vivo glutamate transport can enable to verify the functional impact of alterations previously found in in vitro and ex vivo preparations. The use of brain microdialysis to sample the extracellular medium has allowed to
作者: 鎮(zhèn)痛劑    時(shí)間: 2025-3-27 16:28

作者: 我要威脅    時(shí)間: 2025-3-27 19:41

作者: defray    時(shí)間: 2025-3-28 00:15
https://doi.org/10.1007/978-3-531-91562-3inical studies, the monitoring of glutamate has revealed tight links between the variations of its interstitial concentration and those of other metabolic biomarkers and partial pressure in oxygen within tissue. The use of microdialysis has allowed to monitor glutamate over several days in patients
作者: 四牛在彎曲    時(shí)間: 2025-3-28 03:05
Sandrine Parrot,Luc DenoroyIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
作者: Lice692    時(shí)間: 2025-3-28 08:00

作者: 并入    時(shí)間: 2025-3-28 12:49
Biochemical Approaches for Glutamatergic Neurotransmission
作者: 伙伴    時(shí)間: 2025-3-28 17:14

作者: mitten    時(shí)間: 2025-3-28 21:50

作者: oxidant    時(shí)間: 2025-3-29 01:41
Journalismus als soziales Systemh the potential to design drugs that target desired receptor responses at the exclusion of those leading to adverse effects. Collectively, these newer paradigms of drug action offer the promise for discovery of therapeutics with favorable outcomes and minimized adverse effects within the delicate CN
作者: 一窩小鳥    時(shí)間: 2025-3-29 03:37
Bürgerfunk als Vielfaltsreserveral methods for integrating MD with microchip electrophoresis (ME) have been described. Microdialysis coupled to microchip electrophoresis (MD-ME) can provide rapid analysis of complex samples using sample injection volumes less than 100?nL. However, the design and construction of MD-ME devices requ
作者: faucet    時(shí)間: 2025-3-29 08:47
https://doi.org/10.1007/978-3-658-02417-8 technology, including sample derivatization, injection procedures, modes of separation and their effects on analytical performance such as sensitivity, temporal resolution in glutamate monitoring and potential to simultaneously determine other neurotransmitters will be reviewed and discussed. Final
作者: Anthology    時(shí)間: 2025-3-29 13:55

作者: 不滿分子    時(shí)間: 2025-3-29 16:58
Identification of Glutamatergic Neurons,n transgenic mice has greatly facilitated the identification and manipulation of glutamatergic neurons. We will describe a multidisciplinary approach including neuronal track tracing, in situ hybridization, immuno-fluorescence, and immuno-electron microscopy that has allowed us the identification of
作者: Blood-Clot    時(shí)間: 2025-3-29 20:36

作者: 直言不諱    時(shí)間: 2025-3-30 03:48

作者: PLIC    時(shí)間: 2025-3-30 05:25

作者: 無(wú)效    時(shí)間: 2025-3-30 09:27
Brain Glutamate Monitoring by Microdialysis and Separation Methods with a Special Focus on Capillar technology, including sample derivatization, injection procedures, modes of separation and their effects on analytical performance such as sensitivity, temporal resolution in glutamate monitoring and potential to simultaneously determine other neurotransmitters will be reviewed and discussed. Final
作者: PAN    時(shí)間: 2025-3-30 12:32
Zusammenfassung und Konsequenzencs in the brain, especially glutamate, the most abundant excitatory neurotransmitter. Here, we discuss recent imaging approaches, particularly with a focus on the design and application of genetically encoded indicator iGluSnFR, in analyzing glutamate transients in vitro, ex vivo, and in vivo.
作者: emission    時(shí)間: 2025-3-30 19:39
Gesellschaftliche Differenzierungs for several CNS disorders. Herein, we describe selected compounds that alter extracellular concentration of glutamate by modulating the function of glutamate transporters. Their relevance for further understanding glutamate transport mechanisms and for drug discovery and therapy development is also discussed.
作者: 后退    時(shí)間: 2025-3-31 00:47

作者: MUT    時(shí)間: 2025-3-31 03:37
Christian Nuernbergk,Christoph Neubergeronotropic and metabotropic glutamate receptors may play crucial roles in the pathophysiology of a variety of psychiatric, neurologic as well as other peripheral disorders. In this chapter, the author discusses the glutamatergic system as potential clinical biomarkers for human blood and cerebrospinal fluid monitoring.
作者: Malaise    時(shí)間: 2025-3-31 06:05
https://doi.org/10.1007/978-3-531-91562-3 chronic pain compared to patients suffering from spasticity, with a stress on peculiarities on such a monitoring. We provide also a detailed discussion on the significant usefulness of microdialysis and its technical and methodological limits in the specific field of clinical research.




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