標(biāo)題: Titlebook: Bioassays in Experimental and Preclinical Pharmacology; Karuppusamy Arunachalam,Sreeja Puthanpura Sasidhar Book 2021 The Editor(s) (if app [打印本頁] 作者: GALL 時間: 2025-3-21 17:42
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作者: misshapen 時間: 2025-3-21 22:38
Phytochemical Analysis,s and hence various levels of research are concentrated on it. This chapter deals with the quantitative and qualitative analyses of different metabolites like total phenolics, flavonoids, saponins, tannins and phytosterols. In detail, the Folin-Ciocalteu colourimetric assay to analyse the total phen作者: 偽證 時間: 2025-3-22 02:29
Preclinical Drug Dose Calculation,art in drug research, is significant as it varies among species. Hence the pharmacokinetics and pharmacodynamics need to consider on dose fixation and various methods are available for this, few of which are described in this chapter. The conversion based on normalization of dose-to-body surface are作者: Lignans 時間: 2025-3-22 04:34
Toxicology Studies: In Vitro and In Vivo,l lines with the measurement of cell damage and an in vivo studies comprising acute and sub-acute toxicity steps using animals are well described in this chapter with detailed formulas and tables. Alamar Blue method, micronucleus and comet tests evaluating the chromosome/DNA level damage and analysi作者: 腐蝕 時間: 2025-3-22 11:52 作者: 展覽 時間: 2025-3-22 16:19 作者: glisten 時間: 2025-3-22 19:45
Animal Experiments on the Cardiovascular System,sk factors, while its treatment relies on reducing the risk factors like lowering bad cholesterol and reducing blood pressure (BP). This chapter deals with the various protocols related to the risk factors of cardiovascular disease that include the procedures like obtaining electrocardiogram (ECG) a作者: cardiovascular 時間: 2025-3-23 00:53 作者: Libido 時間: 2025-3-23 01:59 作者: 踉蹌 時間: 2025-3-23 08:42
Experiments of Antifungal Activities,tory concentration (MIC) and the minimum fungicidal concentration (MFC) are determined by the broth microdilution techniques while the synergistic antimicrobial activity of the tested complexes combined with two antifungal drugs (ketoconazole and amphotericin B) made by checkerboard and biofilm assa作者: Aerate 時間: 2025-3-23 12:23 作者: CERE 時間: 2025-3-23 13:59 作者: 詞匯 時間: 2025-3-23 21:37
Animal Experiment of Anti-nociceptive Activities,al mediators. In this chapter, we discuss the well-established procedures for the investigation of anti-nociceptive activity of crude extract and drugs with acetic acid-induced writhing, hot plate and formalin-induced paw licking tests. In the hot plate test, we analysed prolongation of nociception 作者: DEI 時間: 2025-3-23 22:52
Experiments of Antioxidant Activities,.), nitric oxide radical (NO·) and lipid peroxyl radical (LOO·) that cause damage to cellular components such as DNA, proteins, carbohydrates and lipids. Endogenous enzymatic (synthetic/physiological) antioxidants like phytochemicals, vitamins and exogenous non-enzymatic (natural) antioxidants like 作者: MAL 時間: 2025-3-24 06:10
Animal Experiments of Hepatoprotective Activities,roxidation of liver tissues, depletion in the tissue glutathione (GSH) levels, elevated the levels of biochemical markers like serum glutamate oxaloacetate transaminase (SGOT/AST) and serum glutamate pyruvate transaminase (SGPT/ALT) triglycerides, cholesterol, bilirubin and alkaline phosphatase. Thi作者: Antecedent 時間: 2025-3-24 07:53 作者: 物質(zhì) 時間: 2025-3-24 14:12 作者: excursion 時間: 2025-3-24 16:49 作者: 伴隨而來 時間: 2025-3-24 21:57
1949-2448 both in vitro and in vivo protocols for full coverage of theThis detailed book explores protocols for a wide array of preclinical pharmacology and toxicology evaluations to be applied to chemical drugs and their development through .in vitro., involving tissues and cell lines, and in vivo models, us作者: 宣誓書 時間: 2025-3-25 01:11
Frédéric Azevedo,Luc Gombert,Frédéric Suter various methods are available for this, few of which are described in this chapter. The conversion based on normalization of dose-to-body surface area and animal equivalent dose determination is explained with the guidelines for calculations.作者: Culpable 時間: 2025-3-25 04:40 作者: 出價 時間: 2025-3-25 08:46
Preclinical Drug Dose Calculation, various methods are available for this, few of which are described in this chapter. The conversion based on normalization of dose-to-body surface area and animal equivalent dose determination is explained with the guidelines for calculations.作者: 鐵砧 時間: 2025-3-25 14:38
Standard Procedure for Anaesthesia in Preclinical Experiments,es, which are conferred in this chapter with pre- and post-procedures, calculation examples for anaesthetic agent preparation, standard volumes of agents administered in animals and the animal handling.作者: 拋棄的貨物 時間: 2025-3-25 18:14
Book 2021r development through .in vitro., involving tissues and cell lines, and in vivo models, using animals as experimental systems, utilized to conduct pharmacological research. Written for the .Springer Protocols Handbooks. series, the methodologies included in this collection have been standardized by 作者: 現(xiàn)實(shí) 時間: 2025-3-25 21:40
Toxicology Studies: In Vitro and In Vivo,ng the toxicity effect of drug in cell cycle are the main protocols discussed here. The animal studies in acute and sub-acute tests evaluate the different physiological and neurological changes through various parameters in stipulated days, along with haematological and biochemical parameters followed in sub-acute method.作者: 單獨(dú) 時間: 2025-3-26 02:20 作者: MURAL 時間: 2025-3-26 08:13
Animal Experiments on the Cardiovascular System,nd blood pressure (BP) signals and myocardial ischemia induction. These methods involve the determination of BP, ECG, plasma concentration, and the histopathological analysis of heart tissues, which are also described here.作者: 遷移 時間: 2025-3-26 09:35
Animal Experiments of Anti-Diarrhoeal Activities,s. The effects of the extract on intestinal secretion are investigated by measuring the volume of the intestinal content and by dosing the electrolytes (H./K. pump-ATPase) in the intestinal content by the colorimetric method.作者: PANG 時間: 2025-3-26 15:14
Animal Experiments of Central Nervous System (CNS),ke behaviour. Finally, lipid profiles such as total cholesterol, triglycerides (TG) and high-density lipoprotein (HDL)-cholesterol, very-low-density lipoprotein (VLDL) behavioural analysis are evaluated. This chapter provides the clear step-wise methods with calculations for the antidepressant activity in OFT, ORT and EPM models of depression.作者: JOG 時間: 2025-3-26 20:05 作者: Dna262 時間: 2025-3-26 23:37
Thu D. Nguyen,Raj Vaswani,John Zahorjanbed. The stepwise standardized procedures of blood collection, including vein blood collection, collection from tail vein, through cardiac puncture, from posterior vena cava and orbital sinus, are discussed with safety measures for the storage.作者: Blazon 時間: 2025-3-27 02:53
Volunteer Computing on Clusters,nd blood pressure (BP) signals and myocardial ischemia induction. These methods involve the determination of BP, ECG, plasma concentration, and the histopathological analysis of heart tissues, which are also described here.作者: 非秘密 時間: 2025-3-27 08:47
Lecture Notes in Computer Sciences. The effects of the extract on intestinal secretion are investigated by measuring the volume of the intestinal content and by dosing the electrolytes (H./K. pump-ATPase) in the intestinal content by the colorimetric method.作者: 痛打 時間: 2025-3-27 09:45 作者: 陳腐思想 時間: 2025-3-27 15:54
Book 2021l, .Bioassays in Experimental and Preclinical Pharmacology. aims to assist undergraduate and postgraduate students, research scholars, scientists, and other academicians performing research in the vital field of drug discovery..作者: Neutropenia 時間: 2025-3-27 20:23
Anca I. D. Bucur,Dick H. J. Epemaoxide (NO) determination and scratch assay for testing the proliferation of fibroblast cells and inflammatory response in AGS cells model—elucidate the detailed and standardized protocols for the in vitro assays with cell lines.作者: CLEAR 時間: 2025-3-28 00:39
Job Scheduling for the BlueGene/L System,ray ionization mass spectrometry (ESI-MS) analysis. Besides, the procedure of HPLC-LC-ESI tandem mass spectrometry (HPLC-LC-ESI-MS/MS) that helps to identify the phenolic compounds in extract is also described in this chapter.作者: amyloid 時間: 2025-3-28 02:29
Eric W. Parsons,Kenneth C. Sevciksed in this chapter. The protocols thus help to investigate a great spectrum of antifungal pointing action of extract/drugs and its possible mode that confirming its high cytotoxic activity against fungal strains.作者: 癡呆 時間: 2025-3-28 06:31
https://doi.org/10.1007/b107134s via the ERK pathway, myofibroblast differentiation, the synthesis, production and maturation of collagen, re-epithelialization, and angiogenesis. Eventually, antioxidant action methods are also included.作者: violate 時間: 2025-3-28 11:35 作者: 哭得清醒了 時間: 2025-3-28 15:05 作者: SPER 時間: 2025-3-28 21:28 作者: JOG 時間: 2025-3-28 23:54
Experiments of Antifungal Activities,sed in this chapter. The protocols thus help to investigate a great spectrum of antifungal pointing action of extract/drugs and its possible mode that confirming its high cytotoxic activity against fungal strains.作者: HAUNT 時間: 2025-3-29 05:09
Animal Experiment of Wound Healing Activity,s via the ERK pathway, myofibroblast differentiation, the synthesis, production and maturation of collagen, re-epithelialization, and angiogenesis. Eventually, antioxidant action methods are also included.作者: 忙碌 時間: 2025-3-29 07:59
Animal Experiment of Anti-nociceptive Activities,he incidences of contractions of the abdomen, elongation of the body, twisting of the trunk and/or pelvis ending are considered as complete writhing which is counted. In formalin-induced nociception, the licking or biting of the injected paw is then recorded from 0 to 5?min as neurogenic phase and 15 to 30?min for inflammatory phase.作者: 任意 時間: 2025-3-29 12:46 作者: 描繪 時間: 2025-3-29 16:52 作者: harpsichord 時間: 2025-3-29 21:54
Karuppusamy Arunachalam,Sreeja Puthanpura SasidharIncludes detailed protocols that are lab-ready.Features advice from the authors on how best to implement the well-honed techniques.Contains both in vitro and in vivo protocols for full coverage of the作者: characteristic 時間: 2025-3-30 01:25 作者: 愛國者 時間: 2025-3-30 06:55 作者: 采納 時間: 2025-3-30 10:39 作者: 溫順 時間: 2025-3-30 12:30
Frédéric Azevedo,Luc Gombert,Frédéric Suterart in drug research, is significant as it varies among species. Hence the pharmacokinetics and pharmacodynamics need to consider on dose fixation and various methods are available for this, few of which are described in this chapter. The conversion based on normalization of dose-to-body surface are作者: 聰明 時間: 2025-3-30 16:56
Lecture Notes in Computer Sciencel lines with the measurement of cell damage and an in vivo studies comprising acute and sub-acute toxicity steps using animals are well described in this chapter with detailed formulas and tables. Alamar Blue method, micronucleus and comet tests evaluating the chromosome/DNA level damage and analysi作者: 谷物 時間: 2025-3-30 23:08 作者: 欲望 時間: 2025-3-31 02:42
Thu D. Nguyen,Raj Vaswani,John Zahorjan follow systematic approach since it may affect the results. Therefore, the procedure of collection, area of collection (blood) and storage of samples need significant assurance of perfect quality. In this chapter, the protocols for various ways of blood collection and pre-procedure steps are descri作者: semble 時間: 2025-3-31 06:38 作者: 山羊 時間: 2025-3-31 11:56 作者: 迅速成長 時間: 2025-3-31 13:51 作者: 使激動 時間: 2025-3-31 21:15
Eric W. Parsons,Kenneth C. Sevciktory concentration (MIC) and the minimum fungicidal concentration (MFC) are determined by the broth microdilution techniques while the synergistic antimicrobial activity of the tested complexes combined with two antifungal drugs (ketoconazole and amphotericin B) made by checkerboard and biofilm assa作者: Brain-Imaging 時間: 2025-3-31 23:35 作者: BANAL 時間: 2025-4-1 02:21 作者: BINGE 時間: 2025-4-1 09:57 作者: flutter 時間: 2025-4-1 10:34 作者: 背書 時間: 2025-4-1 14:33
