標(biāo)題: Titlebook: Bioassay Methods in Natural Product Research and Drug Development; Lars Bohlin,Jan G. Bruhn Book 1999 Springer Science+Business Media Dord [打印本頁(yè)] 作者: ambulance 時(shí)間: 2025-3-21 19:08
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書目名稱Bioassay Methods in Natural Product Research and Drug Development讀者反饋學(xué)科排名
作者: 最高點(diǎn) 時(shí)間: 2025-3-21 21:45
https://doi.org/10.1007/978-3-031-43943-8es themselves and finally, at the highest level, the living communities of ecosystems. The Rio Convention on Biological Diversity deals predominately with three crucial issues: ., and ., These issues are currently the focus of intensive research around the world e.g. on the characterization of genet作者: deforestation 時(shí)間: 2025-3-22 00:43
Shohei Minami,Toshio Endo,Akihiro Nomuraion through exogenous signalcompounds. From the physiological role of the secondary metabolites in plants one can draw some conclusions about the chance of finding new biologically active compounds. In the search for biologically active compounds, particularly young tissues and seedlings seem to be 作者: 過份艷麗 時(shí)間: 2025-3-22 05:31
https://doi.org/10.1007/978-3-030-88224-2ickly and efficiently. In order to accomplish this, the process of selecting which screening leads to pursue or advance has taken center stage as the most critical task in the discovery process. In programs emphasizing natural products as a source of such lead compounds, this task is complicated by 作者: CODA 時(shí)間: 2025-3-22 12:04 作者: aphasia 時(shí)間: 2025-3-22 14:11
Lecture Notes in Computer Sciencenopharmacology. Most traditional medicines have been found by coincidence, or by trial and error, not by systematic research. Thus it is very likely that the majority of useful drugs in nature so far have escaped discovery. This, together with the fact that only a minute fraction of natural sources 作者: 使人入神 時(shí)間: 2025-3-22 17:31
Shohei Minami,Toshio Endo,Akihiro Nomuraficient attention as a resource of possible medicinal agents. At the same time, it has been estimated that over half of the world’s 25 best selling pharmaceuticals for 1991 owed their origin to a natural source material (O’Neill and Lewis, 1993). Another statistic is that approximately 120 plant-der作者: 預(yù)定 時(shí)間: 2025-3-22 22:32 作者: GONG 時(shí)間: 2025-3-23 02:46 作者: 有法律效應(yīng) 時(shí)間: 2025-3-23 07:02 作者: paleolithic 時(shí)間: 2025-3-23 12:35
Process Tracking for Parallel Job Control, asthma. About 10 % of the children are said to have asthmoid disorders. In the U.S.A., 5.000 people die from asthma per year. In Germany it is 1 lethal case within 100.000 inhabitants per year. In Germany, also one sixth of the population is suffering from rheumatism. Out of them, 1.2 million have 作者: Substance 時(shí)間: 2025-3-23 13:51 作者: 多余 時(shí)間: 2025-3-23 20:30
https://doi.org/10.1007/3-540-39997-6f building the World’s premier natural products based drug discovery company. Our rationale is based on the role played by natural products as drugs or as lead molecules from which developed structure activity relationships has lead to a new drug. Cragg, et al. in an analysis of new chemical entitie作者: 脫離 時(shí)間: 2025-3-24 01:41
Lecture Notes in Computer Sciencewhich can rise to US$ 100 million. This figure itself can rise to several times that number if the costs of candidates which do not complete the development process are taken into consideration. Although it is impossible to give exact figures, it has been reliably estimated that the chance for a sin作者: 秘傳 時(shí)間: 2025-3-24 05:08 作者: 我的巨大 時(shí)間: 2025-3-24 07:20 作者: 走調(diào) 時(shí)間: 2025-3-24 14:01
https://doi.org/10.1007/978-94-011-4810-8chemistry; development; drug; drug development; drug discovery; evolution; future; lead; natural products; ph作者: 小畫像 時(shí)間: 2025-3-24 17:06
978-94-010-6019-6Springer Science+Business Media Dordrecht 1999作者: 反感 時(shí)間: 2025-3-24 21:21 作者: propose 時(shí)間: 2025-3-25 01:25 作者: Inkling 時(shí)間: 2025-3-25 03:53 作者: 討人喜歡 時(shí)間: 2025-3-25 08:55 作者: FLIP 時(shí)間: 2025-3-25 14:57 作者: 地名表 時(shí)間: 2025-3-25 16:29
Process Tracking for Parallel Job Control,al case within 100.000 inhabitants per year. In Germany, also one sixth of the population is suffering from rheumatism. Out of them, 1.2 million have chronic polyarthritis. Therefore, there is a real need for new and better anti-inflammatory drugs and concepts.作者: nautical 時(shí)間: 2025-3-25 23:00
Cyclooxygenase and 5-Lipoxygenase as Targets for Medicinal Plant Research,al case within 100.000 inhabitants per year. In Germany, also one sixth of the population is suffering from rheumatism. Out of them, 1.2 million have chronic polyarthritis. Therefore, there is a real need for new and better anti-inflammatory drugs and concepts.作者: faddish 時(shí)間: 2025-3-26 03:26
Shohei Minami,Toshio Endo,Akihiro Nomuraived chemical compounds are currently used as drugs. Many of these are extracted and purified directly from plants (Farnsworth ., 1985). A recent success story is the market for ., (Ginkgoaceae) extracts in disorders of peripheral blood circulation and geriatry. Annual sales in Europe are estimated at US $ 500 million (Sticher 1993).作者: 獸皮 時(shí)間: 2025-3-26 07:45 作者: 露天歷史劇 時(shí)間: 2025-3-26 11:21
https://doi.org/10.1007/978-3-031-43943-8lopment has resulted in that the world’s genetic and species diversity increasingly are viewed as industrial assets of great potential economic value. New search strategies for identifying valuable areas or taxa for biodiversity prospecting are rapidly under development, using a variety of phylogenetic, biogeographic, genetic, and ecological data.作者: Congeal 時(shí)間: 2025-3-26 13:25 作者: 你正派 時(shí)間: 2025-3-26 17:35
Lecture Notes in Computer Science screening bioassays including primary and broad bioassays and different specialized screening bioassays including lower organisms, isolated subcellular systems, isolated cellular systems, isolated organs of vertebrates and whole animals are systematically reviewed.作者: Hiatal-Hernia 時(shí)間: 2025-3-27 00:44
Marta Jaros,Dalibor Klusá?ek,Jiri Jarosubjects (patients with allergic, autoimmune, and/or rheumatic diseases) or transplantation patients. There are even examples of plant derived substances with more or less selective anti-lymphoproliferative effects.作者: NICHE 時(shí)間: 2025-3-27 05:04 作者: 不感興趣 時(shí)間: 2025-3-27 08:49
Chemodiversity and the Biological Role of Secondary Metabolites, Some Thoughts for Selecting Plant rs. Such compounds are particularly of interest for screening for antimicrobial and antitumor activity. Inducible pathways may also be the cause of considerable variation in different collections of plant material.作者: 受辱 時(shí)間: 2025-3-27 10:52 作者: 階層 時(shí)間: 2025-3-27 14:23
, Assays for Activity-Guided Enrichment of Immunomodulatory Plant Constituents,ubjects (patients with allergic, autoimmune, and/or rheumatic diseases) or transplantation patients. There are even examples of plant derived substances with more or less selective anti-lymphoproliferative effects.作者: 種族被根除 時(shí)間: 2025-3-27 18:42
Book 1999rojects are presented for the first time. .This volume bridges the gap between academic and industrial researchand scientists, and should be required reading in drug companies andfaculties of pharmacy, as well as serving scientists in pharmacognosy,pharmacology, phytochemistry, natural products and drug discovery.作者: cajole 時(shí)間: 2025-3-27 23:49 作者: 刺激 時(shí)間: 2025-3-28 02:52
Expediting Drug Development through the Use of Plants,gle drug to complete the whole process from the research idea to the marketplace is about one in ten thousand. This article looks at the causes of failure in the development process and attempts to give an account of some of the ways in which the use of plants either as leads or as a source of the drug material itself can expedite this process.作者: placebo 時(shí)間: 2025-3-28 08:45 作者: 催眠 時(shí)間: 2025-3-28 13:43 作者: adequate-intake 時(shí)間: 2025-3-28 15:50 作者: CONE 時(shí)間: 2025-3-28 19:53
The Future Role of Natural Products in Drug Discovery, protection in the next 5 years. Never before have so many important drugs come off patent in such a short period of time and the major pharmaceutical companies are racing to find new drugs to replace the billions of dollars in sales they stand to lose.作者: 性滿足 時(shí)間: 2025-3-29 01:44
The use of Receptor Binding, a Very Specific, High Capacity Screening Method, in the Identificatione broad term ‘combinatorial chemistry’ result in an unprecedented output of new compounds which are subjected to high throughput screening procedures. Thus, natural product research is obliged to make use of these new possibilities, or is doomed to fade away.作者: 合唱隊(duì) 時(shí)間: 2025-3-29 06:49
Natural Products with Antiprotozoal Activity,lso made an important impact. The polyene antibiotic ionophores monensin, lasalocid, narasin and salinomycin, are widely used in the prophylaxis of avian coccidiosis, and amphotericin B, is given in the treatment of leishmaniasis and some forms of amoebiasis. The aminoglycoside-aminocyclitol paromom作者: rheumatology 時(shí)間: 2025-3-29 10:48 作者: predict 時(shí)間: 2025-3-29 12:38 作者: ascend 時(shí)間: 2025-3-29 17:55 作者: 不透明 時(shí)間: 2025-3-29 23:18 作者: maudtin 時(shí)間: 2025-3-30 02:58
B. B. Zhou,R. P. Brent,D. Walsh,K. Suzakilso made an important impact. The polyene antibiotic ionophores monensin, lasalocid, narasin and salinomycin, are widely used in the prophylaxis of avian coccidiosis, and amphotericin B, is given in the treatment of leishmaniasis and some forms of amoebiasis. The aminoglycoside-aminocyclitol paromom作者: Abjure 時(shí)間: 2025-3-30 04:07 作者: Collar 時(shí)間: 2025-3-30 11:13
https://doi.org/10.1007/3-540-39997-6and natural product chemistry. Most large pharmaceutical companies have at least ten fold more research effort devoted to medicinal chemistry then natural product discovery. If we look at the area of anti-infective therapy the absolute numbers favor the natural products. Here 59 new products for the作者: 向下 時(shí)間: 2025-3-30 16:10
Bioassay Methods in Natural Product Research and Drug Development作者: BRIDE 時(shí)間: 2025-3-30 20:03
Bioassay Methods in Natural Product Research and Drug Development978-94-011-4810-8作者: capillaries 時(shí)間: 2025-3-30 20:42 作者: 類人猿 時(shí)間: 2025-3-31 03:45 作者: 十字架 時(shí)間: 2025-3-31 05:32
Evolving Strategies for the Selection, Dereplication and Prioritization of Antitumor and HIV-Inhibiickly and efficiently. In order to accomplish this, the process of selecting which screening leads to pursue or advance has taken center stage as the most critical task in the discovery process. In programs emphasizing natural products as a source of such lead compounds, this task is complicated by
