標(biāo)題: Titlebook: Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular; Eric Reid,J. D. Robinson,Ian D. Wilson Book 1988 Sp [打印本頁] 作者: 萬能 時間: 2025-3-21 18:16
書目名稱Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular影響因子(影響力)
書目名稱Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular影響因子(影響力)學(xué)科排名
書目名稱Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular網(wǎng)絡(luò)公開度
書目名稱Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular被引頻次
書目名稱Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular被引頻次學(xué)科排名
書目名稱Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular年度引用
書目名稱Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular年度引用學(xué)科排名
書目名稱Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular讀者反饋
書目名稱Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular讀者反饋學(xué)科排名
作者: 頌揚國家 時間: 2025-3-21 22:25
Analysis of Eicosanoids by GC-MS/MSlar substances often found in much higher concentration. Hence past assays of insufficient specificity have given erroneous values. GC-MS, which is more specific than RIA, is effective for structure elucidation and assay of eicosanoids and metabolites, yet may be insufficiently selective at low eico作者: avenge 時間: 2025-3-22 03:52
Quantitative Determination of Several Prostaglandins and Thromboxane B2 in the Isolated Perfused Rated rat brain, perfused with a synthetic fluoro-carbon perfusion medium. After perfusion, the brains were frozen in isopentane at ?56°, freeze-dried at ?40° and pulverized (liq. N.). The powder (~100 mg) was spiked with 4 deuterated analytes and extracted with methanol/water. The supernatants were ap作者: 凝乳 時間: 2025-3-22 07:26
Analytical Methods for [3H]-Enisoprost, an Anti-Secretory PGE1 Analogue, and its MetabolitesLRC* were used. These methods were scaled up to allow isolation and purification of urinary metabolites. These were identified by GC-MS of their ME-MO-TMS and PFB-MO-TMS derivatives. The latter provided mol. wt. data from the intense [M-PFB]. ions formed by NCI with ammonia, and the former provided 作者: Gratuitous 時間: 2025-3-22 10:07
Identification of a New Metabolite of Leukotriene B4 by RP-HPLC and GC-MS Analysisunds precludes separating all of them within one system. Therefore RP-HPLC systems have been developed to isolate particular groups of compounds such as peptidoLT’s or LTB. and its isomers. A RP-HPLC system now described allows the separation of a new metabolite of LTB. from LTB. and its trans isome作者: 狂亂 時間: 2025-3-22 13:53
Radioimmunoassay of Eicosanoids: Its Application in the Development of Anti-Inflammatory and Analgesy including regulation of microvascular blood flow and permeability, leukocyte chemotaxis, hyperalgesia and anaphylaxis. Consequently, in recent years considerable effort has been expended in the search for agents that block the synthesis and antagonize the actions of these autocoids. Most of the bi作者: Guileless 時間: 2025-3-22 19:36 作者: Pageant 時間: 2025-3-22 22:32
The Stereochemical Analysis of Monohydroxyfatty Acids, Particularly 12-Hydroxy-5,8,10,14-Eicosatetrahanism of formation of these compounds stimulated investigation of their stereochemistry. Chiral methods using HPLC have been developed for separation and quantification of the hydroxyl enantiomers as well as for their multi-mg preparation.作者: 好開玩笑 時間: 2025-3-23 02:20
Analysis of the Actions of Anti-Inflammatory Drugs, with Particular Reference to Effects on Interleustimulated or unstimulated leucocytes. Assays developed for two main IL’s, viz. IL-1 and IL-2, include cell responses such as production of other mediators, or reactions (e.g. proliferation, aggregation) whose specificity depends on the responsiveness of the cell type as well as the purity of the ex作者: evasive 時間: 2025-3-23 07:45
Immunoassay of Beclomethasone 17,21-Dipropionate and Metabolites levels down to 0.1 (plasma) or 1 (urine) ng/ml. The 3-O-carboxymethyloxime derivative of BDP was coupled by a mixed-anhydride reaction to bovine serum albumin (BSA) for raising a rabbit antiserum, or to [..] iodohistamine to provide a radiolabel. Known BDP metabolites and endogenous steroids had ne作者: 名義上 時間: 2025-3-23 13:26
HPLC Analysis of Anti-Inflammatory Agents (Non-Steroidal and Steroidal)es fluorescence or EC). HPLC is also convenient in percutaneous absorption studies on AI agents in gels and creams. Solvent extraction is often not necessary if the drug concentration, e.g. in plasma, is relatively high: precipitation of plasma proteins is often sufficient, provided that a pre-colum作者: obstruct 時間: 2025-3-23 14:39 作者: Influx 時間: 2025-3-23 21:17
Enantiomeric Analysis of 2-Phenylpropionic Acid NSAID’s in Biological Fluids by HPLCtion of these agents by both direct and indirect methods are briefly reviewed. Problems associated with the choice of HPLC mobile phase for the resolution of, and derivatization methods for the formation of, stable diastereoisomeric derivatives are illustrated with reference to pirprofen. The applic作者: HERTZ 時間: 2025-3-23 22:30
Jewish Christians and Christian Jewss measurement in complex biological fluids entails problems. To circumvent these, attention has been turned to metabolites of PGD. that may have longer half-lives and be less susceptible to dehydration. Metabolism in primates including man was known to proceed via the formation of PGF-ring compounds作者: Arthritis 時間: 2025-3-24 03:16
Richard H. Popkin,Gordon M. Weinerlar substances often found in much higher concentration. Hence past assays of insufficient specificity have given erroneous values. GC-MS, which is more specific than RIA, is effective for structure elucidation and assay of eicosanoids and metabolites, yet may be insufficiently selective at low eico作者: semble 時間: 2025-3-24 08:56 作者: 傷心 時間: 2025-3-24 12:54
Jewish Conscience of the ChurchLRC* were used. These methods were scaled up to allow isolation and purification of urinary metabolites. These were identified by GC-MS of their ME-MO-TMS and PFB-MO-TMS derivatives. The latter provided mol. wt. data from the intense [M-PFB]. ions formed by NCI with ammonia, and the former provided 作者: BLANK 時間: 2025-3-24 16:01
,The Formative Years: Péguy 1877–1902,unds precludes separating all of them within one system. Therefore RP-HPLC systems have been developed to isolate particular groups of compounds such as peptidoLT’s or LTB. and its isomers. A RP-HPLC system now described allows the separation of a new metabolite of LTB. from LTB. and its trans isome作者: 原始 時間: 2025-3-24 20:23
Jewish Conscience of the Churchy including regulation of microvascular blood flow and permeability, leukocyte chemotaxis, hyperalgesia and anaphylaxis. Consequently, in recent years considerable effort has been expended in the search for agents that block the synthesis and antagonize the actions of these autocoids. Most of the bi作者: GLIDE 時間: 2025-3-24 23:31
https://doi.org/10.1007/978-3-030-88960-9hibition of gastric secretions and platelet aggregation. They are also implicated in imflammatory reactions, kidney function and immune responses [1]. Several articles in this vol. and in Vol. 16 deal with the determination of PG’s and TX’s and investigation of their biosynthesis. To define and eluc作者: 存心 時間: 2025-3-25 04:02
Stanley Marcus: Fashioning a Cityhanism of formation of these compounds stimulated investigation of their stereochemistry. Chiral methods using HPLC have been developed for separation and quantification of the hydroxyl enantiomers as well as for their multi-mg preparation.作者: Axon895 時間: 2025-3-25 09:45 作者: 發(fā)微光 時間: 2025-3-25 13:25
Buddhism and German-Jewish Orientalism, levels down to 0.1 (plasma) or 1 (urine) ng/ml. The 3-O-carboxymethyloxime derivative of BDP was coupled by a mixed-anhydride reaction to bovine serum albumin (BSA) for raising a rabbit antiserum, or to [..] iodohistamine to provide a radiolabel. Known BDP metabolites and endogenous steroids had ne作者: Libido 時間: 2025-3-25 18:44 作者: llibretto 時間: 2025-3-25 21:57
Listening to the Anxious AtheistsIn man, diclofenac is extensively metabolized mainly by oxidative pathways followed by glucuronide conjugation. A small percentage of the original drug is glucuronidated directly. As diclofenac has a high total clearance, the plasma levels are low, necessitating a specific and very sensitive assay f作者: aphasia 時間: 2025-3-26 00:43 作者: Hyaluronic-Acid 時間: 2025-3-26 05:53 作者: 不可救藥 時間: 2025-3-26 08:42 作者: 小說 時間: 2025-3-26 15:25 作者: CAB 時間: 2025-3-26 17:07 作者: 取消 時間: 2025-3-26 22:48
Immunoassay of Beclomethasone 17,21-Dipropionate and Metabolites levels down to 0.1 (plasma) or 1 (urine) ng/ml. The 3-O-carboxymethyloxime derivative of BDP was coupled by a mixed-anhydride reaction to bovine serum albumin (BSA) for raising a rabbit antiserum, or to [..] iodohistamine to provide a radiolabel. Known BDP metabolites and endogenous steroids had negligible cross-reactivity.作者: Harness 時間: 2025-3-27 03:39 作者: 沉思的魚 時間: 2025-3-27 08:23
The Assay of Diclofenac and Metabolites: A ReviewIn man, diclofenac is extensively metabolized mainly by oxidative pathways followed by glucuronide conjugation. A small percentage of the original drug is glucuronidated directly. As diclofenac has a high total clearance, the plasma levels are low, necessitating a specific and very sensitive assay for pharmacokinetic studies.作者: Spinal-Tap 時間: 2025-3-27 13:29
,The Formative Years: Péguy 1877–1902,unds precludes separating all of them within one system. Therefore RP-HPLC systems have been developed to isolate particular groups of compounds such as peptidoLT’s or LTB. and its isomers. A RP-HPLC system now described allows the separation of a new metabolite of LTB. from LTB. and its trans isomers.作者: mortgage 時間: 2025-3-27 16:19
Stanley Marcus: Fashioning a Cityhanism of formation of these compounds stimulated investigation of their stereochemistry. Chiral methods using HPLC have been developed for separation and quantification of the hydroxyl enantiomers as well as for their multi-mg preparation.作者: 牛的細(xì)微差別 時間: 2025-3-27 18:04
Buddhism and German-Jewish Orientalism, levels down to 0.1 (plasma) or 1 (urine) ng/ml. The 3-O-carboxymethyloxime derivative of BDP was coupled by a mixed-anhydride reaction to bovine serum albumin (BSA) for raising a rabbit antiserum, or to [..] iodohistamine to provide a radiolabel. Known BDP metabolites and endogenous steroids had negligible cross-reactivity.作者: 止痛藥 時間: 2025-3-28 01:34
Palgrave Series in Asian German Studieses fluorescence or EC). HPLC is also convenient in percutaneous absorption studies on AI agents in gels and creams. Solvent extraction is often not necessary if the drug concentration, e.g. in plasma, is relatively high: precipitation of plasma proteins is often sufficient, provided that a pre-column is used.作者: Venules 時間: 2025-3-28 02:14
Listening to the Anxious AtheistsIn man, diclofenac is extensively metabolized mainly by oxidative pathways followed by glucuronide conjugation. A small percentage of the original drug is glucuronidated directly. As diclofenac has a high total clearance, the plasma levels are low, necessitating a specific and very sensitive assay for pharmacokinetic studies.作者: CLAM 時間: 2025-3-28 07:48 作者: MAPLE 時間: 2025-3-28 12:01 作者: Lice692 時間: 2025-3-28 17:59 作者: 溫和女孩 時間: 2025-3-28 19:22
Analytical Approaches Adopted during the Development of FlurbiprofenBrief mention is made of the assay and stereoselective metabolism of ibuprofen. The NSAID. given attention in this article is flurbiprofen, the development of which entailed successive assay methods. That outlined below was used when the number of samples to be assayed was escalating.作者: ANNUL 時間: 2025-3-28 23:10 作者: Kidney-Failure 時間: 2025-3-29 06:16 作者: paleolithic 時間: 2025-3-29 09:24 作者: EVADE 時間: 2025-3-29 13:52 作者: 誘導(dǎo) 時間: 2025-3-29 15:55 作者: 代替 時間: 2025-3-29 21:35
Book 1988 induction decay to NMR practi tione:ts, who may pardon the term ‘Fid‘ as introduced editorially. The convention for ,0C‘ throughout the book is ‘0‘. Undefined but well-known abbreviations include GC, HPLC and TLC. MS (mass spectrometry), NPD (nitrogen-phosphorus detector), tr (retention time) and R作者: MARS 時間: 2025-3-30 03:44 作者: innovation 時間: 2025-3-30 04:30 作者: 疏遠(yuǎn)天際 時間: 2025-3-30 08:43
Radioimmunoassay of Eicosanoids: Its Application in the Development of Anti-Inflammatory and Analges. Within a mechanistic approach to new drug development, RIA of eicosanoids can be used at the pre-clinical and clinical stages of drug development and now plays an integral part in hypothesis testing and in the progression of pharmacological curiosities to effective medicines.作者: ONYM 時間: 2025-3-30 13:13
Jewish Christians and Christian Jewsation is given to the identification of these metabolites,-their sites of formation, to analytical implications, and especially to the actual methods used, notably HPLC, GC after derivatization, and MS.作者: 搖擺 時間: 2025-3-30 18:30 作者: 獎牌 時間: 2025-3-30 20:46
Book 1988withstanding the shortcomings or lateness of some texts, authors are thanked for compiling them amidst other pressures. Elsevier and the American Chemical Society are also thanked, for Figures now reproduced with source acknowledgement. This Editor has generally respected authors‘ phrasing, whilst s作者: 有惡意 時間: 2025-3-31 02:39
turer. Notwithstanding the shortcomings or lateness of some texts, authors are thanked for compiling them amidst other pressures. Elsevier and the American Chemical Society are also thanked, for Figures now reproduced with source acknowledgement. This Editor has generally respected authors‘ phrasing作者: NICE 時間: 2025-3-31 06:57 作者: 感激小女 時間: 2025-3-31 09:29 作者: ABYSS 時間: 2025-3-31 13:48
Jewish Christians and Christian Jewsplied to a BondElut RP-18 cartridge. The eluate was dried down, the residue dissolved in ether/p.e.? and the solution applied to a silica gel column. The eluate was dried down and the residue subjected to methoximation, PFB esterification and silylation. The derivatized COP’s were separated and quantitated by NCI GC-MS.
