標題: Titlebook: Bioactive Sphingolipids in Cancer Biology and Therapy; Yusuf A. Hannun,Chiara Luberto,Lina Marie Obeid Book 2015 Springer International Pu [打印本頁] 作者: 與生 時間: 2025-3-21 19:16
書目名稱Bioactive Sphingolipids in Cancer Biology and Therapy影響因子(影響力)
書目名稱Bioactive Sphingolipids in Cancer Biology and Therapy影響因子(影響力)學科排名
書目名稱Bioactive Sphingolipids in Cancer Biology and Therapy網絡公開度
書目名稱Bioactive Sphingolipids in Cancer Biology and Therapy網絡公開度學科排名
書目名稱Bioactive Sphingolipids in Cancer Biology and Therapy被引頻次
書目名稱Bioactive Sphingolipids in Cancer Biology and Therapy被引頻次學科排名
書目名稱Bioactive Sphingolipids in Cancer Biology and Therapy年度引用
書目名稱Bioactive Sphingolipids in Cancer Biology and Therapy年度引用學科排名
書目名稱Bioactive Sphingolipids in Cancer Biology and Therapy讀者反饋
書目名稱Bioactive Sphingolipids in Cancer Biology and Therapy讀者反饋學科排名
作者: dissent 時間: 2025-3-22 00:13
Role of Sphingolipids in Hematological Malignancies: Lymphoproliferative Disorderside, the putative different functions of ceramide species, and their metabolic regulation have been investigated in regard to induction of cell death of many types of cancers. Recently not only ceramide but also sphingosine-1-phosphate (S1P), sphingomyelin (SM) and ceramide-1-phosphate are being app作者: 混合,攙雜 時間: 2025-3-22 03:23 作者: Evacuate 時間: 2025-3-22 04:38
Sphingolipids as Mediators of Breast Cancer Progression, Metastasis, Response and Resistance to Chem has been put into developing a thorough understanding of the molecular and genetic events that contribute to tumor progression due to mounting evidence that breast cancers are driven by predictable and identifiable genetic mutations, Sphingolipids modulate many of the growth, apoptosis, inflammator作者: inflate 時間: 2025-3-22 12:37
Role of Sphingolipids in Non-melanoma Skin Cancerarcinoma (BCC) and squamous cell carcinoma (SCC), both of which arise from malignant keratinocytes, the major cell type in the epidermis of the skin. Most cases of NMSC can be cured by existing new surgical techniques and chemo- or radiotherapy. However, NMSC remains a leading cause of cancer-relate作者: 知識 時間: 2025-3-22 13:39 作者: 膠狀 時間: 2025-3-22 18:48 作者: 和音 時間: 2025-3-22 23:04
Dietary Sphingolipids in Colon Cancer Preventioner day. In the intestinal tract, they are digested to the bioactive metabolites ceramide and free sphingoid bases. These metabolites regulate proliferation, survival and cell death, alter gene expression levels and modulate functions such as angiogenesis, migration and invasion. They also impact loc作者: 疲勞 時間: 2025-3-23 01:40 作者: 旁觀者 時間: 2025-3-23 07:40 作者: 擔心 時間: 2025-3-23 10:52
Sphingolipids in the Pathogenesis of Head and Neck and Lung Cancers: Translational Aspects for Theran addition to being important for membrane structures. With the identification of enzymes involved in metabolism of various bioactive molecules of the sphingolipid pathway, a better and broader understanding has been gained of how cells control signaling events, such as proliferation and apoptosis, 作者: 放肆的我 時間: 2025-3-23 15:01 作者: Dealing 時間: 2025-3-23 19:31
Systems Biology Approaches for Studying Sphingolipid Signalingee other chapters in this volume). However, much remains unknown in terms of the signaling mechanisms and downstream pathways affected by sphingolipids in cancers, such as which sphingolipid pathway is involved, which sphingolipid species contributes to a specific cancer’s biologic response, and whi作者: Immunoglobulin 時間: 2025-3-24 02:09 作者: Gratulate 時間: 2025-3-24 04:47 作者: lethal 時間: 2025-3-24 07:44
Sphingoproteomics: Proteomic Strategies to Examine Sphingolipid Biologyclude roles in inflammation, proliferation, survival, and metastasis. Sphingolipids can exert these effects through an increasing number of identified interacting cellular targets. To facilitate the understanding of the intrinsic biology of sphingolipids and the development of sphingolipid-based the作者: NADIR 時間: 2025-3-24 14:42
Utilization of Caged Ceramide and Ceramide 1-Phosphate Analogs for Monitoring Cellular Events after es, ceramide and ceramide 1-phosphate. Biophysical studies were carried out after a 6-bromo-7-hydroxycoumarinyl-ceramide conjugate was inserted into model bilayer membranes. Uncaging with long-wavelength UV light liberated .-palmitoylceramide, and reorganization of lipid domains in the bilayer was m作者: 怕失去錢 時間: 2025-3-24 16:33 作者: Ingredient 時間: 2025-3-24 19:10
978-3-319-35371-5Springer International Publishing Switzerland 2015作者: GLIB 時間: 2025-3-25 01:48 作者: 黃瓜 時間: 2025-3-25 04:06 作者: flutter 時間: 2025-3-25 10:25
Ian C. W. Hardy,Daniel R. Smithr bioactive role in apoptosis and differentiation. Ever since, hematological malignancies have represented a powerful model to discover and dissect sphingolipid-related functions in the context of cell proliferation, differentiation, autophagy, immunological responses and neoplastic transformation. 作者: BRINK 時間: 2025-3-25 12:19
https://doi.org/10.1007/978-3-031-23880-2 has been put into developing a thorough understanding of the molecular and genetic events that contribute to tumor progression due to mounting evidence that breast cancers are driven by predictable and identifiable genetic mutations, Sphingolipids modulate many of the growth, apoptosis, inflammator作者: Blemish 時間: 2025-3-25 18:30 作者: GIST 時間: 2025-3-25 23:00
Clavius and Mathematics in the ,, of cancer death and consequently has become a significant public health problem worldwide in fair-skinned populations. The discovery of the prevalent mutation BRAFV600E, which drives melanoma cell growth, has made this oncogenic protein an ideal therapeutic target. However, the beneficial effects o作者: 運動吧 時間: 2025-3-26 03:07
New Transculturalisms, 1400–1800ountries. Although recent studies provide knowledge of the molecular signaling pathways that are implicated in colon carcinogenesis, treatments and outcomes still need further improvement. Bioactive sphingolipids, such as ceramide, sphingosine, and sphingosine-1-phosphate (S1P), are signaling molecu作者: 中子 時間: 2025-3-26 08:01 作者: deadlock 時間: 2025-3-26 09:48
https://doi.org/10.1007/978-981-99-2464-6ely, current therapy is inefficient and advanced HCC is highly resistant to chemotherapy, making early diagnosis crucial for survival. HCC develops in the course of chronic liver disease and inflammation. Progressive non-alcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease作者: averse 時間: 2025-3-26 15:13
https://doi.org/10.1007/978-981-99-2464-6e ceramide, the aliphatic backbone of sphingolipids, can act as a powerful tumor censor; a favorable attribute. However, cancer cells are equipped to efficiently inactivate ceramide via various metabolic routes: glycosylation to form glucosylceramide, and hydrolysis, which generates sphingosine and 作者: resuscitation 時間: 2025-3-26 20:19
Jesus in an Age of Enlightenmentn addition to being important for membrane structures. With the identification of enzymes involved in metabolism of various bioactive molecules of the sphingolipid pathway, a better and broader understanding has been gained of how cells control signaling events, such as proliferation and apoptosis, 作者: ENNUI 時間: 2025-3-26 23:59
Jesus in an Age of Enlightenmentt lethal cancers in humans. A major player is sphingosine-1-phosphate, that pressures GBM cells to exhibit its hallmarks, leading to increased proliferation, invasiveness, stemness, angiogenesis and death resistance, this indicating a fine balance and interplay between S1P function and this malignan作者: 分開如此和諧 時間: 2025-3-27 03:16
https://doi.org/10.1007/978-1-349-05513-5ee other chapters in this volume). However, much remains unknown in terms of the signaling mechanisms and downstream pathways affected by sphingolipids in cancers, such as which sphingolipid pathway is involved, which sphingolipid species contributes to a specific cancer’s biologic response, and whi作者: AND 時間: 2025-3-27 07:31
https://doi.org/10.1007/978-3-211-49647-3 signal transduction. As the already immense database of identified bioactive SL subspecies continues to expand, the need for structure-specific identification and quantification continues to rise. The characterization and analysis of the sphingolipidome by mass spectrometry has advanced steadily ov作者: Hamper 時間: 2025-3-27 09:42 作者: 平淡而無味 時間: 2025-3-27 13:55
https://doi.org/10.1007/978-3-211-49647-3clude roles in inflammation, proliferation, survival, and metastasis. Sphingolipids can exert these effects through an increasing number of identified interacting cellular targets. To facilitate the understanding of the intrinsic biology of sphingolipids and the development of sphingolipid-based the作者: 借喻 時間: 2025-3-27 20:47 作者: 令人不快 時間: 2025-3-28 00:12
Yusuf A. Hannun,Chiara Luberto,Lina Marie ObeidExamines the roles and functions of sphingolipids in the development, progression and treatment of various cancers.Explores the use of innovative approaches for quantitative analysis and imaging which作者: 生命層 時間: 2025-3-28 03:14
http://image.papertrans.cn/b/image/186479.jpg作者: 即席 時間: 2025-3-28 09:00 作者: Paleontology 時間: 2025-3-28 13:24
Book 2015 critical examination of the specific pathways and pathobiologies associated with the altered regulation of sphingolipid metabolism as a contributor to the development and/or maintenance of pathological conditions such as cancer..作者: nonchalance 時間: 2025-3-28 18:26
op novel cancer therapeutics. As well, the volume includes a critical examination of the specific pathways and pathobiologies associated with the altered regulation of sphingolipid metabolism as a contributor to the development and/or maintenance of pathological conditions such as cancer..978-3-319-35371-5978-3-319-20750-6作者: 向下五度才偏 時間: 2025-3-28 21:18 作者: 流浪 時間: 2025-3-29 02:14
Jesus in an Age of Enlightenmentung and head and neck cancers. Specifically, recent discoveries on the roles of sphingolipids in the regulation of head and neck squamous cell carcinoma and lung cancers will be discussed. Moreover, recent efforts on the identification of sphingolipid metabolism related biomarker development will be deliberated.作者: RACE 時間: 2025-3-29 04:18 作者: insolence 時間: 2025-3-29 08:56
Sphingolipids in the Pathogenesis of Head and Neck and Lung Cancers: Translational Aspects for Theraung and head and neck cancers. Specifically, recent discoveries on the roles of sphingolipids in the regulation of head and neck squamous cell carcinoma and lung cancers will be discussed. Moreover, recent efforts on the identification of sphingolipid metabolism related biomarker development will be deliberated.作者: Amenable 時間: 2025-3-29 14:28 作者: Irrigate 時間: 2025-3-29 15:54
Book 2015udes discussions of the innovative techniques and approaches for quantitative analysis and imaging that could significantly impact the general understanding of this topic, and the potential benefit of targeting sphingolipid enzymes to develop novel cancer therapeutics. As well, the volume includes a作者: Antagonist 時間: 2025-3-29 21:24 作者: ACRID 時間: 2025-3-30 00:06 作者: Increment 時間: 2025-3-30 07:58
Sphingolipids as Mediators of Breast Cancer Progression, Metastasis, Response and Resistance to Chemstance. In basal type breast tumors CERT and GCS play a role in resistance to taxanes suggesting that targeting these pathways may be an effective route for the treatment of aggressive triple negative tumors. The role of sphingolipids in Her2-like tumors has not been thoroughly studied. However, CER作者: Counteract 時間: 2025-3-30 11:47
Role of Sphingolipids in Non-melanoma Skin Cancerf cells that it originates from. Emerging evidence suggests that sphingolipids play an important role in regulating these cellular responses of keratinocytes and the homeostasis of the epidermis. In this review, we will discuss the role for sphingolipids and their metabolizing enzymes in regulating 作者: generic 時間: 2025-3-30 14:31
Dysregulation of Sphingolipid Metabolism in Melanoma: Roles in Pigmentation, Cell Survival and Tumortes and enzymes that contribute to this metabolic dysregulation in melanoma, to discuss the emerging roles of sphingolipids on melanogenesis, tumor microenvironment and melanoma progression, and to highlight relevant therapeutic approaches applicable for melanoma treatment.作者: Decline 時間: 2025-3-30 19:48
Colon Cancer: The Role of Sphingolipid Metabolic Enzymes, suggesting that the balance between these potent bioactive lipids may dictate cell fate. In this chapter, we review the roles of these bioactive sphingolipids and their metabolic enzymes in colitis, colitis associated cancer, and colorectal cancer.作者: ventilate 時間: 2025-3-30 21:36
