標(biāo)題: Titlebook: Beta-Lactams; Novel Synthetic Path Bimal K. Banik Book 2017 Springer International Publishing AG 2017 Beta Lactams research.Synthesis antib [打印本頁] 作者: 明顯 時(shí)間: 2025-3-21 16:37
書目名稱Beta-Lactams影響因子(影響力)
書目名稱Beta-Lactams影響因子(影響力)學(xué)科排名
書目名稱Beta-Lactams網(wǎng)絡(luò)公開度
書目名稱Beta-Lactams網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Beta-Lactams被引頻次
書目名稱Beta-Lactams被引頻次學(xué)科排名
書目名稱Beta-Lactams年度引用
書目名稱Beta-Lactams年度引用學(xué)科排名
書目名稱Beta-Lactams讀者反饋
書目名稱Beta-Lactams讀者反饋學(xué)科排名
作者: 光滑 時(shí)間: 2025-3-21 22:15
,Role of Transition Metal Reagents in β-Lactam Synthesis: New Paradigms,ed considerable interest of the research community around the world. Their applications as key synthons for biologically active natural/unnatural compounds, valuable building blocks and diverse pharmacological activities have accelerated the efforts in β-lactam synthesis. In this regard, transition 作者: 長矛 時(shí)間: 2025-3-22 01:02 作者: TAP 時(shí)間: 2025-3-22 08:08
,-Lactams from Ketene-Imine Cycloadditions: An Update,thermal and photochemical means, with examples of stable and isolable ketenes, as well as reactive intermediates, sometimes observable by spectroscopic methods. Preparations of bis(.-lactams) by such processes are also described.作者: 懲罰 時(shí)間: 2025-3-22 11:27
,Recent Approaches Toward the Generation of Molecular Diversity Based on β-Lactam Structures,caffolds yielded useful small molecule tools for chemical genetic studies of cellular protein functions, apart from “classic” drug discovery approaches. In this chapter, the latest developments for the transformation of β-lactam monocyclic moieties into complex and diverse structures are discussed. 作者: Bravado 時(shí)間: 2025-3-22 13:54
,Synthesis of Five-Membered Heterocycles Through β-Lactam Ring-Expansion Reaction,d in compounds with other pharmacological profile, such as antidiabetic, anticancer and cholesterol absorption inhibition among others. Besides, to its biological relevance, the β-lactam ring is a versatile building block for the synthesis of a huge amount of acyclic and cyclic structures by selecti作者: Patrimony 時(shí)間: 2025-3-22 19:24 作者: 討人喜歡 時(shí)間: 2025-3-22 21:43
,Solid Phase Synthesis of β-Lactams: Results and Scope,s clinically relevant antibiotics, such as penicillins, cephalosporins, carbacephems, monobactam, etc. Therefore, continued efforts are being made in developing new methods for synthesizing β-lactams more efficiently than the previous methods. Solid phase organic (SPS) synthesis of β-lactams has gai作者: keloid 時(shí)間: 2025-3-23 04:51 作者: 變形詞 時(shí)間: 2025-3-23 08:53
Nanochemistry in Drug Design,mically modified organic compounds of natural origin, e.g. penicillins, cephalosporins, macrolides, fluoroquinolones, etc. The efficacy of these drugs is declining due to spreading of antibiotic resistance around the microbial world. Herein, we examine current strategies of designing new antimicrobi作者: Blood-Clot 時(shí)間: 2025-3-23 13:42 作者: 凝結(jié)劑 時(shí)間: 2025-3-23 14:41
,The Never-Ending Story of β-Lactams: Use as Molecular Scaffolds and Building Blocks,ce in the field of antibacterial therapautics, but also because of their role as chiral synthons towards the synthesis of other bioactive heterocycles. In this chapter, we primarily aim at discussing three major issues: Kinugasa reaction as a highly successful synthetic route for the synthesis of va作者: compose 時(shí)間: 2025-3-23 20:56
https://doi.org/10.1007/978-3-319-55621-5Beta Lactams research; Synthesis antibiotics beta lactams; Stereochemistry beta lactams; Biological Pro作者: Insatiable 時(shí)間: 2025-3-23 22:37
978-3-319-85711-4Springer International Publishing AG 2017作者: 磨坊 時(shí)間: 2025-3-24 04:29
Bimal K. BanikProvides an essential overview of the field.Written by experienced experts.Covers synthesis, mechanism of formation, biological effects as well as use for the synthesis of other heterocycles.Includes 作者: 招人嫉妒 時(shí)間: 2025-3-24 07:35 作者: 考博 時(shí)間: 2025-3-24 12:57
,-Lactams from Ketene-Imine Cycloadditions: An Update,thermal and photochemical means, with examples of stable and isolable ketenes, as well as reactive intermediates, sometimes observable by spectroscopic methods. Preparations of bis(.-lactams) by such processes are also described.作者: Kaleidoscope 時(shí)間: 2025-3-24 17:49 作者: 歡笑 時(shí)間: 2025-3-24 20:33
Institutionalisierung politischen Handelnsamino acids, alkaloids and taxoids. Their biological behaviour of β-lactam is derived from its unique structure and reactivity. Monocyclic β-lactams, one of its major classes is popular due their wide range of pharmacological applications and the recent interest in this field is towards the monocycl作者: CT-angiography 時(shí)間: 2025-3-25 02:18 作者: aristocracy 時(shí)間: 2025-3-25 04:52
https://doi.org/10.1007/978-3-658-01326-4the synthesis of a variety of mono-, bi- and polycyclic β-lactams since its development in 1996. This novel substrate can be directly alkylated on the nitrogen atom of the β-lactam ring in contrast to commercially available 4-acyloxyazetidin-2-one. Moreover, subsequent cyclization via intramolecular作者: Climate 時(shí)間: 2025-3-25 09:16 作者: fender 時(shí)間: 2025-3-25 13:37 作者: 參考書目 時(shí)間: 2025-3-25 19:19 作者: 動(dòng)脈 時(shí)間: 2025-3-25 21:07
https://doi.org/10.1007/978-3-8350-5509-4s chapter will cover significant success in the synthesis of innovative 2-azetidinones through the formation of a single bond, either C–C or N–C. While the C2–C3 bond formation has scarcely been explored, the intramolecular cyclization through the C3–C4 bond using different approaches are among the 作者: senile-dementia 時(shí)間: 2025-3-26 02:18
https://doi.org/10.1007/978-3-8350-5509-4s clinically relevant antibiotics, such as penicillins, cephalosporins, carbacephems, monobactam, etc. Therefore, continued efforts are being made in developing new methods for synthesizing β-lactams more efficiently than the previous methods. Solid phase organic (SPS) synthesis of β-lactams has gai作者: 真實(shí)的你 時(shí)間: 2025-3-26 05:54 作者: 托運(yùn) 時(shí)間: 2025-3-26 09:16 作者: 咆哮 時(shí)間: 2025-3-26 14:59
Spyros Vliamos,Michel S. Zouboulakis in situ formed ketenes, namely amino-, oxy-, thio-, halo- and alkylketenes, are competent reaction partners which upon reaction with the corresponding .-protected C-aryl-, alkyl-, or acyl-imine give access to β-lactam products with a large variety of substitution patterns at the three available pos作者: Parameter 時(shí)間: 2025-3-26 20:24 作者: BRAND 時(shí)間: 2025-3-26 21:18 作者: BURSA 時(shí)間: 2025-3-27 04:17 作者: arrhythmic 時(shí)間: 2025-3-27 09:05
,β-Lactams Through Single Bond Ring Closing: Methods, Transformations and Bioactivity,mides, the oxidative bond formation and different radical cyclizations, leading to original 2-azetidinones, including some spiro derivatives. Classical methodologies, like the use of Grignard reagents, the base-induced cyclization of β–aminoesters and the application of coupling methods to β–amino a作者: FUSE 時(shí)間: 2025-3-27 13:00 作者: LAP 時(shí)間: 2025-3-27 16:48
Institutionalisierung politischen Handelns deal with the importance and recently developed methodologies for the synthesis of variety of heterocyclic β-lactams. Further, the biological potentials of novel heterocyclic β-lactams have also been described.作者: Deduct 時(shí)間: 2025-3-27 18:46 作者: 改進(jìn) 時(shí)間: 2025-3-28 01:57 作者: 展覽 時(shí)間: 2025-3-28 03:58
https://doi.org/10.1007/978-3-658-01326-4o other known methods based on the condensation of 4-acetoxyazetidin-2-one with alcohols or [2?+?2] cycloaddition with chiral vinyl ethers. Particularly attractive are highly stereoselective approaches to 5-oxacephams and carbacephams which can be easily applied to solid-phase conditions.作者: doxazosin 時(shí)間: 2025-3-28 07:49
https://doi.org/10.1007/978-3-322-83601-4non-β-lactamic) scaffolds, as well as new heterocyclic derivatives of pyrroles, γ-lactones, γ-lactams, oxazinones, imidazolidines, piperazines, piperidines, among others. Finally, the importance of β-lactam-based hybrids as a new source of potential biologically active compounds, have been also highlighted.作者: falsehood 時(shí)間: 2025-3-28 13:54
https://doi.org/10.1007/978-3-8350-5509-4 automation, among others. In this paper, recent advances of solid phase synthesis along with the stereochemistry of β-lactams (2-azetidinone) involving different resins have been discussed covering the literature up to 2015.作者: 圓木可阻礙 時(shí)間: 2025-3-28 17:07
Institutionalising Backwardness,description covering their use and resistance in recent years is performed. Therefore, we report here the medical use of β-lactams as therapeutic agents with the understanding that researchers may find this chapter useful in their endeavor in future research.作者: Meditate 時(shí)間: 2025-3-28 20:05
Institutionalising Backwardness,, nanoparticles self-cytotoxicity, perspectives of targeted drug delivery and application of “green” chemistry, vital for the prospective production of β-lactams nanoformulations with enhanced efficacy and low toxicity.作者: Prostaglandins 時(shí)間: 2025-3-29 01:11
,4-Vinyloxyazetidin-2-one, a Novel Substrate for β-Lactam Synthesis,o other known methods based on the condensation of 4-acetoxyazetidin-2-one with alcohols or [2?+?2] cycloaddition with chiral vinyl ethers. Particularly attractive are highly stereoselective approaches to 5-oxacephams and carbacephams which can be easily applied to solid-phase conditions.作者: triptans 時(shí)間: 2025-3-29 03:18 作者: Accommodation 時(shí)間: 2025-3-29 11:07 作者: hardheaded 時(shí)間: 2025-3-29 13:17 作者: 放牧 時(shí)間: 2025-3-29 19:24 作者: enterprise 時(shí)間: 2025-3-29 20:44
e in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance..978-3-319-85711-4978-3-319-55621-5作者: 類人猿 時(shí)間: 2025-3-30 03:40
